Extensive research into the molecular mechanisms of cancer disease
has heralded a new age of targeted therapy. In malignant cells, key
proteins that are crucial to tumor growth and survival are now
being targeted directly with rationally designed inhibitors. Apart
from monoclonal antibodies, small molecule therapeutics such as
oncogenic protein kinase inhibitors are attracting a vast amount of
investigational attention. This textbook, written by acknowledged
experts, provides a broad overview of the small molecules currently
used for the treatment of malignant diseases and discusses
interesting novel compounds that are in the process of clinical
development to combat cancer.
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