The scope of this book deals with biosensors and microarrays that
take advantage of the specific biological recognition between a
surface-immobilised "probe" and a biological "target" in solution.
In order to preserve the integrity of the biological interaction
taking place on a sensor, surface immobilisation of the probe
should guarantee the preservation of the probe conformation,
orientation and availability. Herein, we will first give a brief
definition of biosensors and their requirements. The use of
organosilanes as anchoring layers for biomolecules on different
materials is then discussed. Finally, the biofunctionalisation of
organosilanes and their applications are described.
General
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