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Genetics, Evolution and Radiation - Crossing Borders, The Interdisciplinary Legacy of Nikolay W. Timofeeff-Ressovsky (Hardcover, 1st ed. 2016)
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Genetics, Evolution and Radiation - Crossing Borders, The Interdisciplinary Legacy of Nikolay W. Timofeeff-Ressovsky (Hardcover, 1st ed. 2016)
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This book is dedicated to the great scientist and outstanding
individual Nikolay Wladimirovich Timofeeff-Ressovsky. The book
brings together a number of brief stories/essays about
Timofeeff-Ressovsky including "Stories told by himself", and
scientific chapters addressing his major research areas: genetics,
radiobiology, radiation ecology and epidemiology, and evolution.
Timofeeff-Ressovsky contributed to several fields of biology and
established new directions of scientific research. He often
repeated the phrase, which would later become famous: "Science
should not be approached with the ferocity of wild animals". In
keeping with that philosophy, the issues discussed here are still
open. Each scientific part starts with a current review; the
chapters present leading scientific schools and views. The main
theme discussed in the genetics part is mutation variability in the
context of linear (replication, transcription, translation) and
conformational template processes, and its dependence on
phylogenetic group. In turn, the radiobiology chapters focus on the
reorganization of DNA, cell, and population variability under
low-dose irradiation, sparking indirect processes and adaptive
response. The radiation ecology and epidemiology parts present data
on the consequences of nuclear plants and related accidents for
ecological systems and human beings. Here some approaches to
estimating radiation risks are also offered. Evolution laws are
demonstrated in the genomic universe, plant-microbe symbiosis,
stabilizing and destabilizing (directional) selection. The last
essay demonstrates the principles of organization operating in
local animal populations, which are approached as social organisms
of complex systemic nature. The chapter 'Radiation-Induced Aging
and Genetic Instability of Mesenchymal Stem Cells: An Issue for
Late Health Effects?' is available open access under a CC BY 4.0
license.
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