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Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection (Hardcover, 1st ed. 2018)
Loot Price: R2,860
Discovery Miles 28 600
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Understanding the Host Immune Response Against Mycobacterium tuberculosis Infection (Hardcover, 1st ed. 2018)
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According to the World Health Organization, approximately one third
of the world's population is latently infected with Mycobacterium
tuberculosis (M. tb [LTBI]), of whom about 9 million have active
tuberculosis (TB). It is estimated that approximately 2 million
individuals die each year from active TB. An estimated 14.4% of
these individuals have HIV and M. tb co-infection. TB has long been
known to be one of the leading causes of death in HIV-infected
individuals. Recent evidence now indicates that individuals with
type 2 diabetes, the elderly, and chronic smokers are also
increasingly susceptible to TB infection, the ability of their
immune system to fight off active TB infection having been
compromised by their condition. This book therefore aims to provide
a detailed review of recent advances in the research that involves
characterizing the host's immune responses against TB infection in
conditions such as HIV, diabetes, chronic cigarette smoking and
aging, and strategies to restore favorable immune responses against
this deadly pathogen.
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