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Chiral Liquid Chromatography (Paperback, Softcover reprint of the original 1st ed. 1989)
Loot Price: R1,574
Discovery Miles 15 740
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Chiral Liquid Chromatography (Paperback, Softcover reprint of the original 1st ed. 1989)
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While working as a chromatographer in the pharmaceutical industry,
it became apparent to the editor that there was a pressing need for
a comprehensive reference text for analysts working on the
resolution of enantiomers by liquid chromatography (LC). This need
arises from the fact that, whereas previously it was very difficult
to determine enantiomers by direct means, there is now a wide
choice of direct LC methods. At the same time, regulatory
authorities have been changing their attitudes towards the
administration of pharmaceuticals as racemates, partly because it
is now possible to study the individual enantiomers. Clearly this
abundance of new information needs to be rationalized. More
importantly, the chiral LC systems which are commercially available
or readily accessible to the practising chromatographer needed to
be reviewed and, to a much greater extent than in existing reviews
or books, discussed in terms of their practical application.
Accordingly this book is very much orientated towards the practical
aspects of these commercially available and readily accessible
chiral LC systems. To this end, it is written for practising
chromatographers by a team of practising, experienced
chromatographers who have spent many years tackling the problems
presented by resolving enantiomers by LC. The practical aspects of
common chiral LC systems cannot be fully understood if discussed in
isolation.
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