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The Reference Materials of the European Communities - Results of Hemocompatibility Tests (Hardcover, 1992 ed.)
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The Reference Materials of the European Communities - Results of Hemocompatibility Tests (Hardcover, 1992 ed.)
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The demand for hemocompatibility is one of the fundamental
requirements for a safe and sufficient application of artificial
surfaces in contact with blood. Thrombus formation and infarctions
of the capillary vascular system after blood-biomaterial
interaction, as well as the activation of the complement system and
the phenomenon of biodegradation, remain problematic areas.
However, medical devices where large areas of artificial surfaces
contact the blood of patients are applied in enormous quantities.
In spite of the significance of this branch of modern medicine and
some spectacular successes in therapy, organ support and organ
replacement, clearly specified criteria and instructions for the
design of devices and artificial blood-contacting surfaces do not
yet exist. Standardized and generally-accepted test procedures for
the precise quantification and validation of events at the
blood-biomaterial interface are urgently needed: their absence
limits safe medical therapy and the development of more efficient
hemocompatible materials. This volume addresses the need for
hemocompatibility standards by presenting the results of tests
performed on the surfaces of the Reference Materials of the
European Communities. Promoted by the EUROBIOMAT Research program
of the European Communities in cooperation with the International
Standards organization, this is a major contribution to the
development of internationally accepted hemocompatibility test
standards.
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