|
Books > Medicine > Clinical & internal medicine > Diseases & disorders > Infectious & contagious diseases
|
Buy Now
Macrolide Antibiotics (Paperback, Softcover reprint of the original 1st ed. 2002)
Loot Price: R4,453
Discovery Miles 44 530
|
|
|
Macrolide Antibiotics (Paperback, Softcover reprint of the original 1st ed. 2002)
Series: Milestones in Drug Therapy
Expected to ship within 10 - 15 working days
|
There are only very few chemical classes of antibiotics in medical
use, and these have originated over a span of more than 60 years of
research. Almost half a century ago, the first member of the
macrolides, erythromycin, was introduced as a treatment option for
bacterial infections. Erythromycin is a very complex fermentation
product obtained from the soil bacterium Saccharopolyspora ery
thraea (originally named Streptomyces erythreus). The success of
erythromycin, based on its efficacy and tolerability, stimulated
researchers throughout the world to undertake intense efforts to
understand the biology and chemistry of macrolides and to use this
experience to improve the properties of this compound class. The
second generation of macrolides, based on chemical modifications of
erythromy cin, is currently being in broad use, especially for
treatment of respiratory tract infections. We presently foresee the
introduction of a new generation of macro lides, i. e. the
ketolides, which have the potential to overcome rising resistance
problems. This monograph is intended to give the interested reader
an overview on "macrolide experience," covering important areas
from basic research to clinical use. Starting from a historic
overview, the essential basic parameters - efficacy,
pharmacokinetics, pharmacodynamics, and pharmacology - are
highlighted in order to introduce the reader to the rationale for
clinical use of macrolides. The following group of chapters cover
the complex chemistry of the macro lactone structures, giving
historic background, basic structure-activity relation ships of
various derivatization strategies, and perspectives for future
discovery of new semisynthetic macrolide antibiotics."
General
Is the information for this product incomplete, wrong or inappropriate?
Let us know about it.
Does this product have an incorrect or missing image?
Send us a new image.
Is this product missing categories?
Add more categories.
Review This Product
No reviews yet - be the first to create one!
|
You might also like..
|
Email address subscribed successfully.
A activation email has been sent to you.
Please click the link in that email to activate your subscription.
Welcome to Loot.co.za!
Sign in / Register |Wishlists & Gift Vouchers |Help | Advanced search
(5)
(1)
