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Head and Neck Cancer - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1995)
Loot Price: R8,075
Discovery Miles 80 750
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Head and Neck Cancer - Basic and Clinical Aspects (Paperback, Softcover reprint of the original 1st ed. 1995)
Series: Cancer Treatment and Research, 74
Expected to ship within 10 - 15 working days
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Throughout the world, head and neck cancer is a major threat to
public health and a significant challenge to both clinicians and
basic scientists. Despite extensive efforts in primary prevention,
screening, early detection, and therapy, long-term survival rates
have not improved substantially in the last three decades. This
book covers a wide range of exciting new findings in both clinical
and basic sciences as they are relevant to head and neck cancer.
These findings have recently enhanced our understanding of head and
neck carcinogenesis at the genetic and molecular levels, offering
the promise of improved preventive and therapeutic strategies. This
book will also present information on the important clinical
advances that have been made in chemoprevention, organ
preservation, and the simultaneous use of chemo therapy and
radiotherapy. The first part provides an overview of the etiology
and biology of head and neck cancer, including an examination of
human papillomaviruses in both benign and malignant lesions. This
section also discusses the carcinogenic process at the genetic and
molecular levels, as well as aberrant squamous differentiation;
increased understanding of these areas has great potential to
translate into new strategies for cancer prevention. The second
part describes recent advances in developing a risk model for head
and neck cancer, as well as the application of genetic
susceptibility data in chemoprevention. This section also includes
overviews of the status of chemoprevention trials and of the
process of invasion and metastasis in head and neck cancer."
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