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The Blood-Cerebrospinal Fluid Barrier (Paperback)
Loot Price: R1,353
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The Blood-Cerebrospinal Fluid Barrier (Paperback)
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Despite the existence of two barrier systems in the brain, research
over the last century has mostly focused on the blood-brain barrier
rather than on the blood-CSF barrier. Today, there is a greater
understanding of the function of the blood-CSF barrier and of the
choroid plexus, a tissue that is the primary site of this barrier.
With the growing number of studies that focus on the role of the
blood-CSF barrier in CNS homeostasis and neurological disorders, a
modern overview of the blood-CSF barrier is long overdue. The
Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the
blood-CSF barrier. Internationally renowned experts discuss the
most recent progress in the field of choroid plexus physiology and
update our knowledge of the function of the blood-CSF barrier. The
book begins with an overview of the development and morphology of
the choroid plexus, and then covers various aspects of its
function, such as the regulation of choroidal blood flow, ion
transport, and the production and transport of polypeptides.
Following an extensive section on the role of the choroid plexus in
CNS disorders, the final section discusses in vitro, in vivo, and
in situ models of the blood-CSF barrier. This unique book analyzes
a wealth of new research on the proven and potential roles of the
choroid plexus/blood-CSF barrier in the brain. It is a valuable
resource that will foster future studies in neuroscience,
pharmacology, and toxicology.
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