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Inducible Enzymes in the Inflammatory Response (Paperback, Softcover reprint of the original 1st ed. 1999)
Loot Price: R1,577
Discovery Miles 15 770
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Inducible Enzymes in the Inflammatory Response (Paperback, Softcover reprint of the original 1st ed. 1999)
Series: Progress in Inflammation Research
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This volume will be of great value to all those researchers in the
area of the inflam matory response, notably academics, clinicians
and members of the pharmaceutical industry. The book has in the
main been restricted to three inducible enzymes, namely nitric
oxide synthase (iNOS), cyclooxygenase (COX-2) and hemeoxygenase
(HO-l), although matrix metalloproteinases, xanthine oxidoreductase
and tissue transgluta minases are reviewed. The modulation of these
enzymes is viewed as possible novel therapeutic advances in the
area of inflammation and also cancer. The latter topic may well be
the subject of a further book. It will be interesting to observe
the progress of such new therapies in the next decade. Already some
of these enzyme modulators have been approved for the treat ment of
inflammatory disease, as evidenced by the new families of COX-2
inhibitors. We believe such advances will herald a series of new
and exciting agents to be included in the clinician's armamentarium
in the constant struggle against inflammatory disease. The editors
wish to thank all contributors to this volume on inducible enzymes.
It should however be stressed that the views expressed by the
authors are personal and do not necessarily reflect those of the
editors. Indeed, the reader may find con flicting statements in a
number of the chapters. We believe that this is entirely appro
priate as this volume reflects the latest work in a rapidly
developing area."
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