Molecular Genetics of Liver Neoplasia (Paperback, 2011 ed.)

Primary liver cancer is the third most deadly and fifth most common cancer worldwide (~500,000 deaths annually), with a sharp increase of incidence in the United States in recent years. Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CC) are the major types of primary liver cancer. Risk factors include gender, hepatitis B virus (HBV), hepatitis C virus (HCV), cirrhosis, metabolism diseases, diabetes, obesity, toxins, excess alcohol consumption and smoking. Liver cancer arises most frequently in inflammatory livers with extensive oxidative stress due to viral hepatitis which causes over 80% of HCC cases worldwide. Currently, survival remains dismal for most HCC and CC patients, largely due to the tumor's aggressiveness at the time of diagnosis and the lack of effective therapy.

General

Imprint:	Springer-Verlag New York
Country of origin:	United States
Series:	Cancer Genetics
Release date:	December 2012
First published:	2010
Editors:	Xinwei Wang • Joe W. Grisham • Snorri S. Thorgeirsson
Dimensions:	235 x 155 x 22mm (L x W x T)
Format:	Paperback
Pages:	399
Edition:	2011 ed.
ISBN-13:	978-1-4614-2731-5
Categories:	Books > Medicine > Clinical & internal medicine > Hepatology Books > Medicine > Other branches of medicine > Pharmacology > General Books > Medicine > Clinical & internal medicine > Diseases & disorders > Oncology > General
LSN:	1-4614-2731-2
Barcode:	9781461427315

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