Recent advances witness the potential to employ nanomedicine and
game-changing methods to deliver drug molecules directly to
diseased sites. To optimize and then enhance the efficacy and
specificity, the control and guidance of drug carriers in
vasculature has become crucial. Current bottlenecks in the optimal
design of drug carrying particles are the lack of knowledge about
the transport of particles, adhesion on endothelium wall and
subsequent internalization into diseased cells. To study the
transport and adhesion of particle in vasculature, the authors have
made great efforts to numerically investigate the dynamic and
adhesive motions of particles in the blood flow. This book
discusses the recent achievements from the establishment of
fundamental physical problem to development of multiscale model,
and finally large scale simulations for understanding transport of
particle-based drug carriers in blood flow.
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