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HLA in Narcolepsy (Paperback, Softcover reprint of the original 1st ed. 1988)
Loot Price: R2,991
Discovery Miles 29 910
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HLA in Narcolepsy (Paperback, Softcover reprint of the original 1st ed. 1988)
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The Second International Symposium on Narcolepsy was held at
Fairchild Auditorium, Stanford University, on 6-7 July 1985 under
the presidency of Drs. William C. Dement and Christian Guillemi
nault. It succeeded the First International Symposium on Narco
lepsy held in La Grande Motte, France, organized by Pierre Pas
souant in July 1975 in commemoration of the 100th anniversary of
the publication of Jean B. E. Gelineau's paper which proposed the
naming of narcolepsy. At the second narcolepsy symposium, many
important research reports on both basic and clinical aspects of
narcolepsy were given by investigators from many countries of the
world. Audience inter est was particularly attracted by the section
on the relationship be tween HLA and narcolepsy, in which recent
evidence that almost all narcoleptic patients are HLA-DR2 positive
was reported by in vestigators from Japan, England, France, Canada,
and the United States. The close relationship between the HLA
antigens, hitherto considered as immune-related genetic markers
encoded by genes on human chromosome 6, and narcolepsy appeared to
open a new approach not only for the research of narcolepsy but
also for the mechanism of sleep in general. Publication of all
these new findings on the association of HLA and narcolepsy was
considered; an outline was worked out and all the groups agreed to
prepare a contribution covering the various aspects of this topic."
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