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Glutamate and Neuropsychiatric Disorders - Current and Emerging Treatments (Hardcover, 1st ed. 2022)
Loot Price: R6,984
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Glutamate and Neuropsychiatric Disorders - Current and Emerging Treatments (Hardcover, 1st ed. 2022)
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This volume provides a comprehensive overview of recent advances in
targeting glutamate signaling for the treatment of major
psychiatric and neurological disorders. It draws on the latest
findings in glutamate neurobiology and offers valuable insights
into the application of translational principles in neuroscience
drug discovery and development. In each chapter, glutamate as a
neurotransmitter, its receptors and transporters, and their
interplay with other neurotransmitters and neurotrophic factors,
are discussed in the context of a specific, highly prevalent and
disabling CNS disease. Most recent and detailed information is
provided on Ischemic Stroke, Chronic Stress, Major Depressive
Disorder, Bipolar Disorder, Autism Spectrum Disorders (ASD),
Posttraumatic Stress Disorder (PTSD), Alzheimer's Dementia,
Schizophrenia, Impulsive Aggression, Substance Use Disorders (SUD),
Amyotrophic Lateral Sclerosis (ALS), Chronic Pain, Multiple
Sclerosis, Parkinson's Disease, Attention Deficit Hyperactivity
Disorder (ADHD), Migraine, Epilepsy and Anxiety disorders.
Moreover, the book includes an extensive overview of glutamatergic
treatments already available on the market, and those which are
currently in pharmaceutical drug development pipelines. The primary
beneficiaries will be neurology and psychiatry specialists and
residents, neuroscientists, neuropharmacologists, pharmaceutical
industry and clinical research organization professionals,
academics, and clinicians working with psychiatric and neurological
patients with comorbidities such as cardiologists, pulmonologists,
and endocrinologists. This book will also appeal to psychiatry and
neurology subspecialists and clinicians working in neuroscience
labs seeking an easy-to-understand yet comprehensive overview of
contemporary evidence-based clinical insights backed by basic
science (preclinical) research evidence. Given its scope, the book
is also a unique and indispensable resource for both preclinical
and clinical neuroscientists, medical advisors, and clinical
research specialists in the pharmaceutical industry. In addition,
it will appeal to neuroscience and neuropsychopharmacology students
and guide them through the complexities of glutamate involvement in
the pathophysiology of the most common debilitating brain diseases
with high unmet medical needs.
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