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Books > Professional & Technical > Biochemical engineering
Systems Immunology and Infection Microbiology provides a large
amount of biological system models, diagrams and flowcharts to
illustrate development procedures and help users understand the
results of systems immunology and infection microbiology. Chapters
discuss systems immunology, systems infection microbiology,
systematic inflammation and immune responses in restoration and
regeneration process, systems' innate and adaptive immunity in
infection process, systematic genetic and epigenetic
pathogenic/defensive mechanism during bacterial infection on human
cells is introduced, and the systematic genetic and epigenetic
pathogenic/defensive mechanisms during viral infection on human
cells. This book provides new big data-driven and systems-driven
systems immunology and infection microbiology to researchers
applying systems biology and bioinformatics in their work. It is
also invaluable to several members of biomedical field who are
interested in learning more about those approaches.
Multifunctional Theranostic Nanomedicines in Cancer focuses on new
trends, applications, and the significance of novel multifunctional
nanotheranostics in cancer imaging for diagnosis and treatment.
Cancer nanotechnology offers new opportunities for cancer diagnosis
and treatment. Multifunctional nanoparticles harboring various
functions-including targeting, imaging, and therapy-have been
intensively studied with the goal of overcoming the limitations of
conventional cancer diagnosis and therapy. Thus theranostic
nanomedicines have emerged in recent years to provide an efficient
and safer alternative in cancer management. This book covers
polymer-based therapies, lipid-based therapies, inorganic
particle-based therapies, photo-related therapies, radiotherapies,
chemotherapies, and surgeries. Multifunctional Theranostic
Nanomedicines in Cancer offers an indispensable guide for
researchers in academia, industry, and clinical settings; it is
also ideal for postgraduate students; and formulation scientists
working on cancer.
Oligonucleotides represent one of the most significant
pharmaceutical breakthroughs in recent years, showing great promise
as diagnostic and therapeutic agents for malignant tumors,
cardiovascular disease, diabetes, viral infections, and many other
degenerative disorders. The Handbook of Analysis of
Oligonucleotides and Related Products is an essential reference
manual on the practical application of modern and emerging
analytical techniques for the analysis of this unique class of
compounds. A strong collaboration among thirty leading analytical
scientists from around the world, the book provides readers with a
comprehensive overview of the most commonly used analytical
techniques and their advantages and limitations in assuring the
identity, purity, quality, and strength of an oligonucleotide
intended for therapeutic use. Topics discussed include: Strategies
for enzymatic or chemical degradation of chemically modified
oligonucleotides toward mass spectrometric sequencing Purity
analysis by chromatographic or electrophoretic methods, including
RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of
sequence-related impurities in oligonucleotides by mass
spectrometry and chromatography Structure elucidation by
spectroscopic methods (IR, NMR, MS) as well as base composition and
thermal melt analysis (Tm) Approaches for the accurate
determination of molar extinction coefficient of oligonucleotides
Accurate determination of assay values Assessment of the overall
quality of oligonucleotides, including microbial analysis and
determination of residual solvents and heavy metals Strategies for
determining the chemical stability of oligonucleotides The use of
hybridization techniques for supporting pharmacokinetics and drug
metabolism studies in preclinical and clinical development Guidance
for the presentation of relevant analytical information towards
meeting current regulatory expectations for oligonucleotide
therapeutics This resource provides a practical guide for applying
state-of-the-art analytical techniques in research, development,
and manufacturing settings.
Despite their widespread impact, computer networks that provide the
foundation for the World Wide Web and Internet have many
limitations. These networks are vulnerable to security threats,
break easily, and have a limited ability to respond to changing
conditions. Recent research on overcoming these limitations has
used biological systems for inspiration, resulting in the
development of biologically-inspired computer networks. These
networks are designed and developed using principles that are
commonly found in natural and biological systems. Biologically
Inspired Networking and Sensing: Algorithms and Architectures
offers current perspectives and trends in biologically-inspired
networking, exploring various approaches aimed at improving network
paradigms. Research contained within this compendium of papers and
surveys introduces studies in the fields of communication networks,
performance modeling, and distributed computing, as well as new
advances in networking.
This concise monograph series focuses on the implementation of
various engineering principles in the conception, design,
development, analysis and operation of biomedical, biotechnological
and nanotechnology systems and applications. Authors are encouraged
to submit their work in the following core topics, but authors
should contact the commissioning editor before submitting a
proposal.
This book provides recent developments and future perspectives of
pulp and paper processing based on biotechnology to replace
conventional environmental unfriendly chemical processes. The use
of microorganism and microbial enzymes in various processes such as
bleaching, deinking, refining, dissolving pulp, debarking &
pitch removal, slime control, wastewater treatment and waste
material valorisation are discussed.
The Era of Artificial Intelligence, Machine Learning and Data
Science in the Pharmaceutical Industry examines the drug discovery
process, assessing how new technologies have improved
effectiveness. Artificial intelligence and machine learning are
considered the future for a wide range of disciplines and
industries, including the pharmaceutical industry. In an
environment where producing a single approved drug costs millions
and takes many years of rigorous testing prior to its approval,
reducing costs and time is of high interest. This book follows the
journey that a drug company takes when producing a therapeutic,
from the very beginning to ultimately benefitting a patient's life.
This comprehensive resource will be useful to those working in the
pharmaceutical industry, but will also be of interest to anyone
doing research in chemical biology, computational chemistry,
medicinal chemistry and bioinformatics.
The Economics of Biotechnology is a highly accessible book dealing
with some of the most crucial issues to arise in this area. Special
attention is paid to consumer, ethical and environmental concerns
as well as questions relating to trade policy, intellectual
property, who will receive the benefits, international development
and the role of international institutions such as the WTO. The
authors examine concerns arising from the application of
biotechnology in the agri-food industrial complex, and many of the
issues discussed also have implications for the medical and
pharmaceutical aspects of biotechnology. Fundamental questions
regarding the application of standard economic analysis to
biotechnology are resolved using traditional neo-classical analyses
as well as less mainstream methods. Through exploring a number of
approaches, original and unexpected conclusions are reached. This
coherent and relevant treatment of the myriad facets of
biotechnology will be welcomed by academics, scholars, and
economists with a specific interest in international economics or
technology, international policymakers, and economic commentators.
Calculations for Molecular Biology and Biotechnology: A Guide to
Mathematics in the Laboratory, Second Edition, provides an
introduction to the myriad of laboratory calculations used in
molecular biology and biotechnology. The book begins by discussing
the use of scientific notation and metric prefixes, which require
the use of exponents and an understanding of significant digits. It
explains the mathematics involved in making solutions; the
characteristics of cell growth; the multiplicity of infection; and
the quantification of nucleic acids. It includes chapters that deal
with the mathematics involved in the use of radioisotopes in
nucleic acid research; the synthesis of oligonucleotides; the
polymerase chain reaction (PCR) method; and the development of
recombinant DNA technology. Protein quantification and the
assessment of protein activity are also discussed, along with the
centrifugation method and applications of PCR in forensics and
paternity testing.
This volume discusses the role of ZIF-8 composites in water
decontamination as an adsorbent and photocatalyst. Metal-organic
frameworks (MOFs) are advanced porous materials and are promising
adsorbents with facile modifications, high specific surface area,
controllable porosity, and tailored surface properties. Water
pollution is a major concern and has endangered human health.
Recently, researchers have designed MOFs for use in remediation.
This book focuses on the characterization of the amorphous phase of
polymers, whether they are pure amorphous or semi-crystalline ones,
above Tg or below Tg, by studying the relaxation of dipoles and
space charges naturally found in their structure after they have
been activated by the application of a voltage field. The
experimental deconvolution of the relaxation modes responsible for
internal motion in the amorphous phase is coupled with a
mathematical procedure (Thermal-Windowing Deconvolution-TWD) that
leads to the understanding of their coupling characteristics which,
it is shown, relate to the state of the material itself, for
instance its non-equilibrium state or its internal stress for
matter belonging to interfaces between aggregated or dispersed
phases. Describes quantitatively the Thermal Stimulated
Depolarization techniques of polymer characterization (TSD, TWD),
i.e. how to decouple the relaxation modes collectively interacting
(interactive coupling) and relate it to the thermodynamic
properties of the amorphous phase. Understands the results of
depolarization in terms of the new physics of polymer interactions:
the Dual-Phase model, here applied to the dipoles-space charge
dynamics. Provides a roaster of CASE STUDIES: practical
applications of the TSD and TWD characterization techniques to
describe coupled molecular motions in resins, medical tissues,
wood, blends and block copolymers interfaces, rubbers, can
coatings, internal stress in molded parts, etc
The 6th volume of Green Chemical Processing considers sustainable
chemistry in the context of innovative and emerging technologies,
explaining how they can support the "greening" of industry
processes. The American Chemical Society's 12 Principles of Green
Chemistry are woven throughout this text as well as the series to
which this book belongs.
Stem Cells: Scientific Facts and Fiction, Third Edition, provides a
state-of-the-art overview on the field of stem cells and their
current applications. The book incorporates the history and
firsthand commentaries in the field from clinical and research
leaders, covering interesting topics of note, including the first
clinical trials to treat Parkinson disease, macular degeneration,
and corneal replacement, the cloning of monkeys, the organoid
field, and CRISPR-edited genomics. In addition, coverage of adult,
embryonic stem cells and iPS cells is included. This new edition
distinguishes itself from the multiplicity of websites about stem
cells with a broad view of the field.
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