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Books > Professional & Technical > Biochemical engineering > Biotechnology > Biosensors
Over the past 20 years, the field of biosensor research has had a
significant impact in both laboratory research and the commercial
sector. Over that period, biosensors have revolutionized the care
and management of diabetes and have had important impacts in
several other areas of clinical diagnostics. Europe, North America
and Asia-Pacific have all seen the rise of small and medium sized
companies seeking technical and application niches in the
manufacture or use of biosensors. The current activity in both gene
and protein 'biochips' can be seen as the latest set of tools that
allow users who are not analytical science practitioners to make
technically complex and reliable biological weapons and the need
for their rapid and reliable detection will need to be met by
devices that have many characteristics in common with biosensors.
Biosensors are becoming increasingly important bioanalytical tools
in the pharmaceutical, biotechnology, food, and other consumer
oriented industries. The technology, though well developed in
Europe, is slowly developing and has begun to generate interest in
the United States only over the past couple of years. Research is
now being directed toward the development of biosensors that are
versatile, economical, and simple to use.
In a bid to develop synthetic molecules and materials that are capable of mimicking biological recognition and function, intensive research in the fields of synthetic receptor technologies, smart materials, synthetic biology and smart indicators has been under way for the past 20-30 years. The development of synthetic receptors continues to grow rapidly. Novel molecular architectures, with ever improving selective binding properties are constantly being described, and in some cases providing much-needed physical insights into the nature of non-covalent interactions and molecular recognition. Such receptor systems are finding increasingly esoteric applications and this book captures the key developments at the synthetic receptor/biology/detection science interface. Both editors have had extensive experience in applying smart materials and synthetic receptors to the development of biosensors. Reddy has developed smart, permselective and biocompatible molecularly imprinted polymers and membrane materials for the sensor/sample interface and the advancement of smart materials-based electrochemical, quartz crystal and optical sensors for medical, food and environmental applications. Thompson has had extensive experience in modified surfaces and development of biosensor technologies. Chapters demonstrate how growing disciplines such as biomimetics, synthetic receptor technologies, pattern recognition and nanotechnology are being used to develop new smart materials for diagnostic sensor and biosensor applications. Postgraduate students and researchers in academia and industry will benefit from this resourceful handbook.
As the elderly population increases, the importance of creating sophisticated information support to humans with limited sensing performance has also grown. This book discusses human and artificial sensing in conjunction with human perception capabilities (auditory, taste, smell, vision, and touch). It also discusses the fusion of this sensing information to find answers to questions such as how we can increase our human "fuzzy" decision capability (perception). The book presents intelligent new technologies that can enhance the natural sensing, perception, and mobility abilities of humans, allowing them to have healthier, more productive, safer lives.
This book gives an overview of the present trends in a rapidly growing interdisciplinary field, namely the research and development of biosensors. It focuses on the development of new biosensors which combine the sensitivity and specificity of biological systems (enzymes, immunosystems, microbial cells, tissue, plants, etc.) with the efficiency of electrochemical transducers. The molecular mechanisms of the processes in biosensors as well as the new methods for transduction and immobilization of biosystems are described in detail. Also, important fields of application are evaluated, i.e. medicinal chemistry including in vivo monitoring, environment pollution monitoring, biotechnology process control, determination of food contaminants and food quality control.
The use of biosensors is accelerating at an enormous rate. Increasingly robust and rapid sensors are being developed for the detection of a wide range of biological molecules and chemicals within the environment. "Biosensors: Methods Express" is a practical guide to all the major classes of electrical and mechanical biosensors in current use. Every chapter discusses the merits and limitations of potential approaches and then provides selected tried-and-tested protocols, with full guidance to ensure success. This book is one which will benefit all researchers who use, or seek to use, biosensors in their research.
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