This book is written for chemists, chemical engineers and chemical technologists who are not expert users of Raman spectroscopy technology. The background to the technique is covered along with its analytical applications. A brief introduction to Raman spectroscopy and instrumentation in general is included, along with detailed explanations of the advantages of Raman over other techniques. Emphasis is placed on the way it has been used to solve a range of analytical problems in the chemical and allied industries.

Biological Applications of Infrared Spectroscopy Infrared spectroscopy (IR) is a well established analytical technique for the identification of organic molecules. However, it is now being used more and more by biologists and biochemists in the analysis of complex biological molecules, such as proteins, lipids and nucleic acids. In this first dedicated volume, which is aimed at the beginner user level, the theory of IR is described and is then related to various biological systems. Chapters on instrumentation, sample preparation and the interpretation of spectra give the reader practical help in using the technique. A comprehensive applications chapter illustrates the diversity and power of this technique in real systems. Analytical Chemistry by Open Learning This series provides a uniquely comprehensive and integrated coverage of analytical chemistry, covering basic concepts, classical methods, instrumental techniques and applications. The learning objectives of each text are clearly identified and the student’s understanding of the material is constantly challenged by self-assessment questions with reinforcing or remedial responses. The overall objective of Analytical Chemistry by Open Learning is to enable the student to select and apply appropriate methods and techniques to solve analytical problems, and to interpret the results obtained.

Frontiers and Advances in Molecular Spectroscopy once again brings together the most eminent scientists from around the world to describe their work at the cutting-edge of molecular spectroscopy. Much of what we know about atoms, molecules and the nature of matter has been obtained using spectroscopy over the last one hundred years or so. Going far beyond the topics discussed in Jaan Laane's earlier book on the subject, these chapters describe new methodologies and applications, instrumental developments and theory, which are taking spectroscopy into still new frontiers. The robust range of topics once again demonstrates the wide utility of spectroscopic techniques. New topics include ultrafast spectroscopy of the transition state, SERS/far-uv spectroscopy, femtosecond coherent anti-Stokes Raman spectroscopy, high-resolution laser induced fluorescence spectroscopy, Raman spectroscopy and biosensors, vibrational optical activity, ultrafast two-dimensional spectroscopy, biology with x-ray lasers, isomerization dynamics and hydrogen bonding, single molecule imaging, spectra of intermediates, matrix isolation spectroscopy and more.

Including contributions from instrument manufacturers! Geological aging, chemical reaction mechanism studies, determination of atomic weights and investigation of metabolic pathways—these are all examples of the truly diverse nature of isotope ratio mass spectrometry (IRMS). With applications in fields as far apart as analytical chemistry and astronomy, geochemistry and biomedical science, it is little wonder that this technique is becoming increasingly popular. In Modern Isotope Ratio Mass Spectrometry,the first comprehensive book written on the subject for twenty-five years, examples from all these areas, and many more,are given. All modern developments in this fascinating field are discussed with special attention paid to technical details and instrumentation.
Features of the book include:

• comprehensive element-by-element review including 94 elements
• applications chapter which stresses multi-disciplinary nature of subject
• instrumentation chapter with contributions from three leading industrialists on state-of-the-art instrumentation

Lasers in Analytical Atomic Spectroscopy Edited by Joseph Sneddon • Terry L. Thiem • Yong-Ill Lee This book focuses primarily on the use of lasers in analytical atomic spectroscopy with optical detection, and also includes a chapter describing the use of lasers in inductively coupled plasma—mass spectroscopy (ICP—MS). The book begins with a brief introduction to atomic spectroscopy and lasers, providing the reader with basic theory and information on instrumentation in conventional atomic spectroscopy. Next, the properties, types, and principles of lasers are discussed using a non-mathematical approach. The main section of the book provides detailed descriptions of the four major areas of laser application in analytical atomic spectroscopy, each discussed by an expert in the field: laser excited atomic fluorescence spectrometry (LEAFS); laser ablation for sample introduction, particularly in inductively coupled plasma—atomic emission spectrometry (ICP—AES) and ICP—MS; laser induced breakdown (emission) spectrometry (LIBS); and laser-enhanced ionization (LEI) spectrometry. Lasers in Analytical Atomic Spectroscopy will be of interest to spectroscopists, analytical chemists, and graduate students in these areas. Also available from VCH Applied Laser Spectroscopy Techniques, Instrumentation, and Applications D.L. Andrews, ed. Hardcover. ISBN 1-56081-023-8 Inductively Coupled Plasmas in Analytical Atomic Spectroscopy Second, Revised and Enlarged Edition A. Montaser and D.W. Golightly, eds. Hardcover. ISBN 1-56081-514-0 Atomic Absorption Spectrometry Second, Completely Revised Edition B. Welz Hardcover. ISBN 3-527-26193-1

Raman spectroscopy is now well established as one of the most versatile techniques for the chemical analysis of molecular species. Major advances have been made in a number of areas in the field in recent years which enable the researcher and practising analytical scientist to solve the complex chemical problems of today. The ten chapters in Modern Techniques in Raman Spectroscopy cover some of the most exciting fields of research in modern Raman techniques, and illustrate the power of modern Raman spectroscopy for molecular analysis in both theoretical and practical problems. The volume opens with chapters on signal expressions and instrumentation in Raman spectroscopy, and then goes on to discuss in detail Fourier and Hadamard Transform Raman spectroscopies, micro-Raman spectroscopy, surface-enhanced Raman spectroscopy, Raman optical activity, coherent and time-resolved techniques and the use of optical fibres in Raman spectroscopy. The chapters are written by leading researchers from a broad range of disciplines. Throughout, applications of the various techniques are discussed. Modern Techniques in Raman Spectroscopy will be of great interest to all those involved in molecular spectroscopy, in both industry and academia. The inclusion of a wide range of modern techniques in a single volume will make this a particularly valuable work to researchers across the whole field of Raman spectroscopy.

The accurate interpretation of infrared spectra of organic structures is an extremely important tool for the analytical chemist. Using up-to-date source material, this volume presents a compilation of the infrared absorption regions of ninety of the most important organic molecular fragments. This highly practical guide introduces the reader to a straightforward technique for determining all the fundamental vibrations of a molecular fragment. The set of normal vibrations and the infrared absorption regions of ninety molecular fragments are then discussed and tabulated. The discussion of each fragment is accompanied by a large number of references. A Guide to the Complete Interpretation of Infrared Spectra of Organic Structures offers the analytical chemist the possibility of a more profound interpretation of infrared spectra. In addition, it assumes only a basic knowledge of infrared spectra, and so will prove very useful for non-specialists who use infrared spectroscopy in analysis.

UV-Visible Spectrophotometry of Water and Wastewater, Second Edition, represents an update to the first book dedicated to the use of UV spectrophotometry for water and wastewater quality monitoring. Using practical examples, the book illustrates how this technique can be a source of new methods of characterization and measurement. Easy and fast to run, this simple and robust analytical technique must be considered as one of the best ways to obtain a quantitative estimation of specific or aggregate parameters (e.g., Nitrate, TOC) and simultaneously qualitative information on the global composition of water and its variation. This second edition presents the current methods and applications for water quality monitoring based on UV spectra, including the most recent works and developments. After the introduction of the basics for UV spectrophotometry understanding, the applications of UV measurement are presented, both from the family of chemicals and water quality parameters and from the type of water. Writing from years of experience in the development and applications of UV systems and from scientific and technical works, the authors provide several useful examples showing the great interest of UV spectrophotometry for water quality monitoring. At the end of the book, the UV spectra library of the first edition is updated with dozens of new chemicals of interest.

The nuclear shell model has had much success when describing nuclear structure. It is able to describe the single-particle states of nuclei, and gives understanding as to how nuclear structure evolves as the number of nucleons changes in a nucleus. This led to the discovery of the so-called magic numbers, which designate particularly stable configurations of protons and neutrons in nuclei. With the advent of radioactive ion beams, it has become possible to probe exotic nuclei to test current theories of nuclear structure. These investigations have led to the discovery of exotic nuclear phenomena, with structures different to those found in stable nuclei. One of these is the N=20 island of inversion, where configurations that appear in stable nuclei become less bound than more exotic particle-hole configurations across a shell gap. Another is the weakening of the magic N=20 shell gap to N=16 as the number of protons is reduced in this isotonic chain. Of particular interest are the magnesium isotopes, which exhibit a swift transition into the island of inversion with 29Mg lying outside and 31Mg lying inside. In addition, 29Mg lies one neutron outside N=16, so is also able to give insight on the weakening of the N=16 shell gap. Mapping this region of the chart of nuclides helps in the understanding of the evolution of this nuclear structure. A useful probe for this task is single-particle transfer reactions. However, these reactions have been hindered by low yields from radioactive ion beams, as well as suffering from kinematic effects that obscure the states that need to be observed. The ISOLDE Solenoidal Spectrometer (ISS), that measures these transfer reactions in a solenoidal magnetic field, was designed to counteract these effects. With the high-yield radioactive ion beams at ISOLDE, CERN, these transfer reactions became viable. Therefore, the nuclear structure of 29Mg was probed using the d(28Mg,p) reaction using this device. This work marks the first measurement using the ISOLDE Solenoidal spectrometer and the first time that a solenoidal spectrometer has been used at an ISOL radioactive beam facility. The measurements highlight the interplay of nucleon-nucleon interactions and the geometry of the nuclear potential in driving observed trends in single-particle structure, in particular the changes in closed shells towards doubly magic 24O

Correlative Light and Electron Microscopy III, Volume 140, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics discussed in this new release include Millisecond time-resolved CLEM, Super resolution LM und SEM of high-pressure frozen C. elegans, Preservation fluorescence, super res CLEM, APEX in Tissue, Corrsight mit IBIDI flowthrough chamber, Correlative Light Atomic Force Electronic Microscopy (CLAFEM), Atmospheric EM CLEM, and High-precision correlation, amongst other topics. Chapters in this ongoing series deal with different approaches for analyzing the same specimen using more than one imaging technique. The strengths and application area of each is presented, with this volume exploring the aspects of sample preparation of diverse biological systems for different CLEM approaches.

Keeping mathematics to a minimum, this book introduces nuclear properties, nuclear screening, chemical shift, spin-spin coupling, and relaxation. It is one of the few books that provides the student with the physical background to NMR spectroscopy from the point of view of the whole of the periodic table rather than concentrating on the narrow applications of 1H and 13C NMR spectroscopy. Aids to structure determination, such as decoupling, the nuclear Overhauser effect, INEPT, DEPT, and special editing, and two dimensional NMR spectroscopy are discussed in detail with examples, including the complete assignment of the 1H and 13C NMR spectra of D-amygdain. The authors examine the requirements of a modern spectrometer and the effects of pulses and discuss the effects of dynamic processes as a function of temperature or pressure on NMR spectra. The book concludes with chapters on some of the applications of NMR spectroscopy to medical and non-medical imaging techniques and solid state chemistry of both I = F1/2 and I > F1/2 nuclei. Examples and problems, mainly from the recent inorganic/organometallic chemistry literature support the text throughout. Brief answers to all the problems are provided in the text with full answers at the end of the book.

Packed with reviews plus new results from the author's laboratories, the first-of-its-kind work offers a timely and authoritative treatise on the use of mass spectral techniques in organic stereochemistry.
Featuring 22 chapters contributed by eminent and active researchers in the field, this unique sourcebook offers comparative information on the use of a variety of mass-spectral techniques to characterize stereoisomers and conformers of both large and small biologically important organic molecules. It also discusses techniques for studying gas-phase conformational equilibria in conformationally mobil systems.
Applications of Mass Spectrometry to Organic Stereochemistry will dramatically aid the lab applications of organic, biological, pharmaceutical, and analytical chemists in university and industrial laboratories.

This third edition of the Encyclopedia of Spectroscopy and Spectrometry, Three Volume Set provides authoritative and comprehensive coverage of all aspects of spectroscopy and closely related subjects that use the same fundamental principles, including mass spectrometry, imaging techniques and applications. It includes the history, theoretical background, details of instrumentation and technology, and current applications of the key areas of spectroscopy. The new edition will include over 80 new articles across the field. These will complement those from the previous edition, which have been brought up-to-date to reflect the latest trends in the field. Coverage in the third edition includes: Atomic spectroscopy Electronic spectroscopy Fundamentals in spectroscopy High-Energy spectroscopy Magnetic resonance Mass spectrometry Spatially-resolved spectroscopic analysis Vibrational, rotational and Raman spectroscopies The new edition is aimed at professional scientists seeking to familiarize themselves with particular topics quickly and easily. This major reference work continues to be clear and accessible and focus on the fundamental principles, techniques and applications of spectroscopy and spectrometry.

This book presents recent developments in ore microscopy to support the work of engineers and scientists actively engaged in the field of mineral raw materials (processing plant engineers in mines, process mineralogists and chemists, exploration geologists, etc.) or in ore deposit research. Textural analysis must be rigorous, and simple to be practical. With this aim, the author proposes a specific and user-friendly systematic for textural analysis. A high-performance tool to acquire, quantify, and process the data applied for automated ore characterization is key to predict ore behavior, a fundamental aim of geometallurgy. The recently developed AMCO System (Automated Microscopic Characterization of Ores) provides the tool, first prototype available using computer vision coupled with reflected light microscopy. This innovation is introduced in the text and discussed through case studies of actual mining problems. This second volume of the book "A Practical Guide to Ore Microscopy" includes references, indexes, and other relevant information, plus Annexes 1 to 5. The latter include ore and gangue mineral indexes and mineral abbreviations (Annex 1), a brief compendium of common mineral associations in the main ore deposit types (Annex 2), an introduction to the procedures and techniques used to prepare polished sections (Annex 3), and the various tables used to identify common ores by direct microscopic observation (Annexes 4 and 5).

The book highlights the current practices and future trends in structural characterization of impurities and degradants. It begins with an overview of mass spectrometry techniques as related to the analysis of impurities and degradants, followed by studies involving characterization of process related impurities (including potential genotoxic impurities), and excipient related impurities in formulated products. Both general practitioners in pharmaceutical research and specialists in analytical chemistry field will benefit from this book that will detail step-by-step approaches and new strategies to solve challenging problems related to pharmaceutical research.

The 6th edition of this classic comprises the most comprehensive guide to infrared and Raman spectra of inorganic, organometallic, bioinorganic, and coordination compounds. From fundamental theories of vibrational spectroscopy to applications in a variety of compound types, it is extensively updated. Part B details applications of Raman and IR spectroscopy to larger and complex systems. It covers interactions of cisplatin and other metallodrugs with DNA and cytochrome c oxidase and peroxidase. This is a great reference for chemists and medical professionals working with infrared or Raman spectroscopies and for graduate students.

This guide to two-dimensional NMR spectroscopy helps the novice who want e the technique, but needs a path through the bewildering array of metho acronyms and the mathematical rigor found in most books.
The authors provide a clear explanation of experiment performance, param lection, data processing and presentation as well as a description of wh rmation is provided by each experiment and how it is extracted and inter They group presentations of two-dimensional NMR experiments according t zation, e.g. COSY, LRCOSY, ZQCOSY, DQCOSY ... for establishing proton-pr nnectivities.
The book also presents spectra of the same model compound using various ues to enable the reader to make direct comparisons and facilitate his e nt selection. Examples of the concerted utilization of various two-dimen NMR experiments to solve complex structural problems are also given.

Annual Reports on NMR Spectroscopy, Volume 108, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

An Introduction to Analytical Atomic Spectrometry is a thoroughly revised and updated version of the highly successful book by Les Ebdon, An Introduction to Atomic Absorption Spectroscopy. The change in title reflects the number of significant developments in the field of atomic spectrometry since publication of the earlier book. New topics include plasma atomic emission spectrometry and inductively coupled plasma mass spectrometry. Key features:

• Self assessment questions throughout book to test understanding
• Keywords highlighted to facilitate revision
• Practical exercises using modern techniques
• Comprehensive bibliography for further reading

The accessibility of An Introduction to Analytical Atomic Spectrometry, makes it an ideal revision text for postgraduates, or for those studying the subject by distance learning.

At a point where most introductory organic chemistry texts end, this problems-based workbook picks up the thread to lead students through a graduated set of 120 problems. With extensive detailed spectral data, it contains a variety of problems designed by renowned authors to develop proficiency in organic structure determination. This workbook leads you from basic problems encountered in introductory organic chemistry textbooks to highly complex natural product-based problems. It presents a concept-based learning platform, introducing key concepts sequentially and reinforcing them with problems that exemplify the complexities and underlying principles that govern each concept. The book is organized in such a way that allows you to work through the problems in order or in selections according to your experience and desired area of mastery. It also provides access to raw data files online that can be downloaded and used for data manipulation using freeware or commercial software. With its problem-centered approach, integrated use of online and digital resources, and appendices that include notes and hints, Problems in Organic Structure Determination: A Practical Approach to NMR Spectroscopy is an outstanding resource for training students and professionals in structure determination. Key Features Offers a concept-based learning platform using a graduated series of problems Presents a problem-based approach to understanding and mastery of structure determinations suitable for students and professionals Includes notes and hints to solutions in the appendices Provides access to raw data files via website for data manipulation using freeware or commercial software Ancillary materials include: A complete set of original fids for all compounds, including both 1D and 2D spectra A full color answer key Complete PDF layouts for all complex natural product problems from section 6 Condensed 1H and 13C spectra

E = mc2 and the Periodic Table . . .
RELATIVISTIC EFFECTS IN CHEMISTRY
This century's most famous equation, Einstein's special theory of relativity, transformed our comprehension of the nature of time and matter. Today, making use of the theory in a relativistic analysis of heavy molecules, that is, computing the properties and nature of electrons, is the work of chemists intent on exploring the mysteries of minute particles.
The first work of its kind, Relativistic Effects in Chemistry details the computational and analytical methods used in studying the relativistic effects in chemical bonding as well as the spectroscopic properties of molecules containing very heavy atoms. The first of two independent volumes, Part A: Theory and Techniques describes the basic techniques of relativistic quantum chemistry. Its systematic five-part format begins with a detailed exposition of Einstein's special theory of relativity, the significance of relativity in chemistry, and the nature of relativistic effects, especially with molecules containing both main group atoms and transition metal atoms.
Chapter 3 discusses the fundamentals of relativistic quantum mechanics starting from the Klein-Gordon equation through such advanced constructs as the Breit-Pauli and Dirac multielectron Hamiltonian. Modern computational techniques, of importance with problems involving very heavy molecules, are outlined in Chapter 4. These include the relativistic effective core potentials, ab initio CASSCF, CI, and RCI techniques. Chapter 5 describes relativistic symmetry using the double group symmetry of molecules and the classification of relativistic electronic states and is of special importanceto chemists or spectroscopists interested in computing or analyzing electronic states of molecules containing very heavy atoms.
An exceptional introduction to one of chemistry's foremost analytical techniques, Relativistic Effects in Chemistry is also evidence of the still unending reverberations of Einstein's revolutionary theory.

Capacitance spectroscopy refers to techniques for characterizing the electrical properties of semiconductor materials, junctions, and interfaces, all from the dependence of device capacitance on frequency, time, temperature, and electric potential. This book includes 15 chapters written by world-recognized, leading experts in the field, academia, national institutions, and industry, divided into four sections: Physics, Instrumentation, Applications, and Emerging Techniques. The first section establishes the fundamental framework relating capacitance and its allied concepts of conductance, admittance, and impedance to the electrical and optical properties of semiconductors. The second section reviews the electronic principles of capacitance measurements used by commercial products, as well as custom apparatus. The third section details the implementation in various scientific fields and industries, such as photovoltaics and electronic and optoelectronic devices. The last section presents the latest advances in capacitance-based electrical characterization aimed at reaching nanometer-scale resolution.

This unique, self-contained resource is the first volume on electron paramagnetic resonance (EPR) spectroscopy in the eMagRes Handbook series. The 27 chapters cover the theoretical principles, the common experimental techniques, and many important application areas of modern EPR spectroscopy. EPR Spectroscopy: Fundamentals and Methods is presented in four major parts: A: Fundamental Theory, B: Basic Techniques and Instrumentation, C: High-Resolution Pulse Techniques, and D: Special Techniques. The first part of the book gives the reader an introduction to basic continuous-wave (CW) EPR and an overview of the different magnetic interactions that can be determined by EPR spectroscopy, their associated theoretical description, and their information content. The second provides the basics of the various EPR techniques, including pulse EPR, and EPR imaging, along with the associated instrumentation. Parts C and D builds on parts A and B and offer introductory accounts of a wide range of modern advanced EPR techniques, with examples of applications. The last two parts presents most of the new advances that do not appear in most of the classical EPR textbooks that focus on CW EPR. EPR Spectroscopy: Fundamentals and Methods contains, in concise form, all the material needed to understand state-of-the-art EPR spectroscopy at the graduate school/research level, whilst the editors have ensured that it presents the topic at a level accessible to newcomers to the field and others who want to know its range of application and how to apply it.

THE PRINCIPLES, APPLICATIONS, AND TRENDS OF A KEY TOOL IN FOOD SCIENCE

Maximizing food potential has become one of the priorities of the food industry and near-infrared spectroscopy (NIRS) is fast becoming a key "ingredient" in achieving that goal. Taking its place among other proven spectroscopic tools, near-infrared spectroscopy facilitates, for example, quality measurements made early in the production when fresh products are still edible, helping to determine whether the product goes to fresh market or to processing and thereby minimizing waste.

Near-Infrared Spectroscopy in Food Science and Technology is one of the few available resources that applies this valuable technique specifically to the food science and technology industries. Written by authors with extensive expertise in NIRS and food science, this comprehensive resource provides an introduction to and overview of the technical aspects of NIRS, including: Basic principles of near-infrared spectroscopy Characteristics of the NIR spectra Instrumentation Sampling techniques Chemometrics

Stressing the practical application of near-infrared technology, the book details the method's use in four key areas of food science and technology: agricultural and marine products, foodstuffs and processed foods, engineering and process monitoring, and food safety and disease diagnosis. Nearly encyclopedic in its coverage, Near-Infrared Spectroscopy in Food Science and Technology will prove a valuable guide for food science professionals as well as scientists and engineers in a wide range of related fields.

This new volume of "Methods in Enzymology" continues the legacy of this premier serial by containing quality chapters authored by leaders in the field. This volume coversFluorescence Fluctuation Spectroscopy
Contains chapters on such topics as Time-integrated fluorescence cumulant analysis, Pulsed Interleaved Excitation, and raster image correlation spectroscopy and number and brightness analysis.
Continues the legacy of this premier serial with quality chapters authored by leaders in the fieldCovers fluorescence fluctuation spectroscopyContains chapters on such topics as time-integrated fluorescence cumulant analysis, pulsed interleaved excitation, and raster image correlation spectroscopy and number and brightness analysis."