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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes
The future of persons with Type 1 Diabetes Mellitus is continuing to "look brighter" with the advent of biomedical technology. Nevertheless, the acute consequences of this disease remains a significant threat. Diabetic ketoacidosis [DKA] remains the most serious challenge for primary care physicians and subspecialists caring for children and young persons with Diabetes Mellitus. Its prevention is possible only among those already diagnosed. Awareness of the etiology and clinical presenting signs among children of all ages is requisite for primary care and emergency department staff [Chapter 1]. While more likely to occur among those with Type 1 diabetes, a significant proportion of children with Type 2 diabetes are also at risk [Chapter 3]. Once diagnosed, the physician team must understand not only what biochemical imbalances must be corrected, but also what life-threatening complications must be avoided [Chapter 1]. The path through that "maze" is not yet fully interpreted; many choices remain as options, but each must be carefully evaluated. Diagnosis among the very young is a challenge because of they lack self-awareness and clarity of signs and symptoms [Chapter 2]. Education of the primary care staff is critical and able to alter the incidence of DKA at the time of diagnosis. Institutions that treat children and adolescents with DKA need an informed Emergency Department as well as Pediatric Intensive Care Facilities. Access to appropriate consultations, such as pediatric endocrinology, cardiology, neurology and neurosurgery are crucial. The initiation of care is critical, and occurs invariably in the Emergency Department [Chapter 4]. Meticulous documentation of fluid composition and volume, insulin administration, vital signs and neurological state of well-being is essential. These will facilitate the transition to the appropriate in-patient service, whose task is to understand the biological impact of fluid rehydration and fluid flux, as well as hypocapnea, hyperglycemia and cranial perfusion [Chapter 5]. The current standards of care all but prevent most of the varied biochemical complications of "appropriate" care for persons with DKA. However, awareness of these possibilities is crucial [Chapter 6]. Yet, one complication remains unexplained and too often unpredicted, and it is devastating to the pediatric patient: cerebral edema. This complication, its prevention and treatment are discussed [Chapter 6]. Type 2 diabetes mellitus is continuing to increase in incidence and prevalence among all ages. Once thought to be "non-ketosis prone" diabetes, now persons undiagnosed or previously diagnosed do obtain DKA. They, however, have other unique medical requirements that must be applied to their treatment [Chapter 3]. Hyperglycemic hyperosmolar state is a complication no longer limited to adults with diabetes or children with Type 2 diabetes mellitus. While the incidence is fortunately lower than that of DKA, its outcome is potentially direr. Appreciation of the unique treatment requirements and guidelines are discussed [Chapter 7]. This monograph provides a comprehensive compendium to those caring for children of all ages with diabetic ketoacidosis, its related disorders and associated conditions.
Diabetes has garnered worldwide attention and research funding as clinicians and researchers seek to better understand its pathogenesis, prevention, complications management, and impact and relationship to other diseases (heart disease, kidney disease, infections, and inflammation). Clinicians are overwhelmed with rapidly evolving developments regarding the science and clinical management of diabetes and are struggling to understand and apply new diabetes information. This book will provide a concise interpretation of translational diabetes research for the purpose of preparing clinicians to understand and effectively deploy new strategies and therapeutics into the clinical care of diabetes patients by examining: the contrast between existing information in the clinical practice versus the basis and need for future clinical trials breakthroughs within clinical trials and methods to incorporate bench to bedside material for the clinical practice the synthesis and interpretation of the scientific principles, trial results, and clinical implications of emerging and translational therapies, and the management strategies for diabetic patients the entire scope of translational diabetes research from biology to screening and prognosis, new therapeutics, insulin, transplantation, and complications management new therapeutic strategies to knowledgeably and effectively equip the practicing clinician assembles information that is scattered throughout the diabetic community into one concise single reference
Given the rapid increase in the worldwide incidence of gestational diabetes, the need for defining the risks and effects associated with raised glucose concentrations in pregnancy is great. Recent large studies are helping to define the risks, as well as identify the benefits of reducing glucose intolerance. Written by an esteemed list of international authors, Gestational Diabetes: Origins, Complications, and Treatment presents timely reviews relating to some of the most important aspects of gestational diabetes, specifically its causes, consequences, and treatments. Divided into five sections, the book begins with a section on metabolism in pregnancy and gestational diabetes, dealing with maternal and foetal glucose metabolism and the controversial area of what actually constitutes gestational diabetes. The next section examines risk factors and causes of gestational diabetes, including the obvious but often overlooked factors-being female and pregnant. The text also outlines environmental and genetic risk factors. The third section deals with the potential complications of gestational diabetes for both mother and offspring, considering short-term and long-term effects. The largest section in the book addresses treatments in an effort to improve the outcome for the mother and the baby. Chapters describe the nutritional approach, considered the cornerstone of treating gestational diabetes, as well as evidence for the role of exercise in its treatment and a useful strategy for treating gestational diabetes pharmacologically. The final section discusses future prospects in screening, diagnosis, prevention, pathophysiology, and treatment of gestational diabetes.
Pancreas and Beta Cell Replacement is the inaugural volume of the Regenerative and Transplant Medicine series. The idea for this new book series spawned from the observation that the regenerative medicine field is progressing at such a fast pace that the way we currently think and practice transplant medicine is rapidly changing, faster than we could ever imagine. This series was therefore conceived to bring together experts from both the transplant and regenerative medicine fields, to share knowledge first, but also to introduce the transplant audience to the remarkable progress that has occurred in regenerative medicine over the past few decades. At the same time, we intend to illustrate to researchers and operators in the regenerative medicine field the numerous platforms that transplant medicine offers for the application of their technologies. To the publisher and the editors of this series and volumes there is no doubt that regenerative medicine will shape and define the future of transplant medicine. This volume focuses on pancreas and beta cell replacement and illustrates how progress in biomaterial sciences, stem cell biology, gene editing, cell, tissue and organ bioengineering and regeneration, along with advances in xenotransplantation are revolutionizing the field. Written by the world's experts in the fields of pancreas, islet and xenotransplantation, as well as regenerative medicine, it represents a valuable educational tool for those in the fields of clinical transplantation, researchers in the field of regenerative medicine, transplant medicine, diabetes and immunology, as well as for medical and health science students, those in academia, the biotech industry and regulatory agencies working to advance the field. At the end of the book, it will become clear to the reader that beta cell replacement offers a vast array of platforms for the application of regenerative medicine technologies to transplant medicine.
The right diet is the foundation for successful management of Diabetes. Published in association with The British Diabetic Association 'Recipes For Health: Diabetes' contains over 200 delicious recipes each carefully designed to meet the special nutrition needs of people with diabetes. Calorie counts and carbohydrate rating are provided for every recipe so it's easy to keep track of your glucose levels. • Children's recipes and advice to help the child with diabetes Azima Govindji was formerly Chief Dietician for the British diabetic Association. Jill Myers is the former Home economist to the British Diabetic association
This is the second edition of the comprehensive guide to diabetes for nurses and is updated to take account of changes in dietary advice, legislation and terminology. The text addresses diabetes as both a biochemical disease and a psychosocial problem. It provides research-based information with suggestions for problem solving and planning. The book is divided into three sections. The first introduces diabetes and examines the altered physiology, the diagnosis, the treatments available and the complications of diabetes. The second section addresses the practice of patient education and the clinical management of diabetes. The third section puts diabetes in care into context. It examines the broader issues involved in diabetes care, including the psychological and ethical aspects of diabetes.
Changing when you eat, sleep and exercise can help you to treat, manage - and even reverse - type 2 diabetes and prediabetes. Circadian rhythms are personal biological clocks that exist in each one of our cells and they influence every aspect of our health. The Circadian Diabetes Code now applies this cutting-edge science to tackling type 2 diabetes. Combining circadian rhythms with intermittent fasting - the worldwide phenomenon launched in Dr Panda's lab - you'll find out how to use this unique protocol to take back control of diabetes and achieve life-long health. - Discover the best way to use intermittent fasting to lose weight - Learn when to exercise to optimise blood glucose levels - Identify ideal times to eat meals and take medication - Why the science of circadian rhythms can help you reverse type two diabetes
This book provides comprehensive information on continuous glucose monitoring (CGM). The first section focuses on the fundamentals of CGM technology, including the principles of CGM, accuracy assessment, operation procedure, management processes, the picture-interpretation methodology, the clinical value of CGM parameters, reference values, clinical applications of CGM report and management systems, and clinical indications. In turn, the second section describes the clinical application of CGM, including assessing blood glucose fluctuation and hypoglycemic effects, detecting hypoglycemia and identifying fasting hyperglycemia. It also describes the role of CGM in connection with specific diseases, such as fulminant type 1 diabetes, gestational diabetes mellitus, steroid diabetes, and insulinoma. The closing chapter outlines the future of CGM. In addition, the book presents typical cases and analyses of nearly a hundred typical monitoring maps. As such, it offers diabetic health care doctors a valuable reference guide to the clinical application of and scientific research on CGM.
UPDATED 2018. This substantially updated new edition offers detailed help on cooking for people with diabetes, including an extensive introduction that helps to explain the condition and offers advice on all aspects of nutrition as well as weight management and exercise. Guidance is given on how to live with diabetes, with advice on managing the condition, alleviating the symptoms, controlling your weight and reducing medication, and bringing together the latest thinking on dietary and lifestyle advice to help understand the condition while offering clear guidelines on what and when to eat. There is then a fantastic selection of tempting but healthy recipes, to help tailor food intake to individual requirements, with recipes to inspire diabetic cooks and enable them to continue to enjoy food with family and friends, with breakfast suggestions, snacks, light meals, main courses, and even puddings and desserts. There is a special section on diabetes in children, as well as advice and support for how to manage the condition through puberty, pregnancy and through the ageing process. The 150 recipes provide everything that is needed for a varied and enjoyable diet, with recipes that friends and family will enjoy such as Roasted Chicken with Mediterranean Vegetables, Grilled Mackerel with Spicy Dahl, and Wild Mushroom and Fontina Tarts. Each recipe comes with complete nutritional notes Fully illustrated with over 650 photographs, this book will be welcome reading for anyone living with diabetes.
Understanding Insulin and Insulin Resistance is written in a simple and clear language illustrated with diagrams that show the complex interplay of various factors in the initiation of insulin resistance. The design is systematic and meticulous, portraying topics in a flow from simple to complex. This resource is intended for a broad audience spanning across biochemistry, medicine, dentistry, academia, physicians, and research scholars. It extends the approach to biochemistry, physiology, metabolism of insulin along with the coverage of pathophysiology of insulin resistance, its effects on the body tissues, and its analysis on insulin resistance syndrome.
Learn the best ways to manage your diet for a full and healthy life with diabetes. Managing Type 2 diabetes may mean making some changes to your diet, but with this easy-to-use recipe book, you can continue to enjoy the food you love. There are over 250 healthy recipes guaranteed to tempt your taste buds - and the best part? Each one will fit perfectly into a healthy eating plan tailored to your wellbeing. Track your glucose, saturated fat, and cholesterol intake with a simple points system while enjoying delicious, nutritious meals and healthy snacks. The Diabetes Cooking Book will be your go-to cookbook to keep your blood sugar levels in balance every day.
Diabetes Digital Health and Telehealth explains, from technologic, economic and sociologic standpoints how digital health and telehealth have come to dominate the management of diabetes. The book also includes information on improved telemedicine tools and platforms for communicating with patients, reviewing medical records, and interpreting data from wearable devices. In addition, evolving wearable sensors such as continuous glucose monitors, closed loop automated insulin delivery systems, cuffless blood pressure monitors, exercise monitors and smart insulin pens are covered.
Metabolic Syndrome: From Mechanisms to Interventions covers all aspects of this complex and multifactorial disease, providing a cutting-edge understanding of the problem of MetS, with a particular focus on its prevention and clinical management. The book discusses practical implementable approaches to its reversal in clinical practice, encompassing the entire spectrum of MetS, from molecular understanding to clinical therapeutics and prevention. This book is a valuable resource for clinicians in multiple specialties, including endocrinologists, diabetologists, hepatologists, gynecologists and researchers in related fields who need a deep understanding of the full range of scientific and clinical aspects of metabolic syndrome.
Sarcopenia: Molecular Mechanism and Treatment Strategies provides answers and guidance on a disease that has serious health consequences in terms of fractures, frailty, disability and diminished quality of life. Written by experts around the world, this book is for all those that care for aging populations. As the global population ages, sarcopenia remains a therapeutic challenge and major public health concern. Difficulties in defining sarcopenia as a clinical phenotype remain and have hindered treatment.
This book aims to aid the selection of the most appropriate methods for use in early phase (1 and 2) clinical studies of new drugs for diabetes, obesity, non-alcoholic fatty liver disease (NAFLD) and related cardiometabolic disorders. Clinical research methods to assess the pharmacokinetics and pharmacodynamics of new diabetes drugs, e.g. the euglycemic clamp technique, have become well-established in proof-of-mechanism studies. However, selection of the most appropriate techniques is by no means straightforward. Moreover, the application of such methods must conform to the regulatory requirements for new drugs. This book discusses the need for new pharmacotherapies for diabetes, obesity and NAFLD and the molecular targets of drugs currently in development. Emerging technologies including functional imaging, circulating biomarkers and omics are considered together with practical and ethical issues pertaining to early phase clinical trials in subjects with cardiometabolic disorders. Translational Research Methods in Diabetes, Obesity, and Non-Alcoholic Fatty Liver Disease is of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.
This second edition volume expands on the previous editions with updates on the commonly used techniques and analysis used by clinicians and scientists to study diabetes. The chapters in this book cover topics such as nutritional models of type 2 diabetes mellitus; the isolation and purification of rodent pancreatic islets of Langerhans; nitric oxide and redox state measurements in pancreatic beta cells; and primary adipocytes as a model for insulin sensitivity. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Type 2 Diabetes: Methods and Protocols, Second Edition is a valuable resource for all researchers who are interested in learning more about this important and evolving field.
Diabetes Mellitus: Impact on Bone, Dental and Musculoskeletal Health focuses on the under recognized and managed conditions associated with diabetes, including impacts on bone health, dental health, hand, and foot disorders, wounds, infections, and musculoskeletal disorders. A full understanding of the relationship of diabetes to skeletal disorders remains elusive and many physicians who deal with such issues are unclear about causes and management. While the macro- and microvascular complications associated with diabetes mellitus are well known, complications associated with bone, dental and musculoskeletal health are not. Endocrinologists, primary care physicians, geriatricians, podiatrists, dentists, and researchers interested in diabetes mellitus associated bone, dental and musculoskeletal disorders will find this to be a comprehensive tome on the topic.
Understanding the importance of nanosciences in diabetes is problematic as some texts can be too technical for the novice. This book uses a reader friendly format suitable not only for practitioners but newcomers as well. It begins with general aspects of nanotechnology and nanomedicine in diabetes. It then discusses glucose and glucose sensors based on functional nanocomposites before moving on to a discussion of insulin and the use of nanoprobes to monitor cell processes in the pancreas. Finally, it explores drugs and other treatments, including second-generation sulfonylurea glipizide loaded biodegradable nanoparticles and nanoparticle-mediated delivery of angiogenic inhibitors in diabetic retinopathy."
This title features expert advice about managing diabetes, with a full guide to healthy living and over 80 delicious recipes. It is a guide to living with diabetes, with helpful advice on managing the condition, alleviating the symptoms, controlling weight and reducing medication. It includes 80 recipes to inspire the diabetic cook, with tempting meals that can be enjoyed with family and friends, such as Wild Mushroom and Fontina Tarts, Grilled Mackerel with Dahl, and Baked Ricotta Cakes with Red Fruits. It brings together the latest thinking on dietary and lifestyle advice to help explain the condition, provide guidelines on what and when to eat, and how to tailor food intake to individual requirements. It covers full nutritional notes, including glycemic load, are supplied for every recipe, with over 400 photographs, including step-by-step sequences for every dish. This authoritative, practical recipe book begins with a detailed introduction on living with diabetes, the necessity of weight control and the importance of exercise. Carbohydrate counting, fat reduction, cholesterol control and portion management are all covered, as is the complex but vital low-glycaemic index. There is a special section on diabetes in children, as well as advice and support for how to manage the condition in puberty, pregnancy and throughout the aging process. The 80 recipes that follow provide everything that is needed for a varied and enjoyable diet, with recipes that friends and family will enjoy eating. Chapters include healthy and sustaining snacks, as well as breakfasts, main dishes, appetizers and puddings. To prove that diabetes does not mean denial, all these satisfying recipes are packed with taste as well as goodnes,s and are presented with full breakdowns of nutritional values.
Given the rapid increase in the worldwide incidence of gestational diabetes, the need for defining the risks and effects associated with raised glucose concentrations in pregnancy is great. Recent large studies are helping to define the risks, as well as identify the benefits of reducing glucose intolerance. Written by an esteemed list of international authors, Gestational Diabetes: Origins, Complications, and Treatment presents timely reviews relating to some of the most important aspects of gestational diabetes, specifically its causes, consequences, and treatments. Divided into five sections, the book begins with a section on metabolism in pregnancy and gestational diabetes, dealing with maternal and foetal glucose metabolism and the controversial area of what actually constitutes gestational diabetes. The next section examines risk factors and causes of gestational diabetes, including the obvious but often overlooked factors-being female and pregnant. The text also outlines environmental and genetic risk factors. The third section deals with the potential complications of gestational diabetes for both mother and offspring, considering short-term and long-term effects. The largest section in the book addresses treatments in an effort to improve the outcome for the mother and the baby. Chapters describe the nutritional approach, considered the cornerstone of treating gestational diabetes, as well as evidence for the role of exercise in its treatment and a useful strategy for treating gestational diabetes pharmacologically. The final section discusses future prospects in screening, diagnosis, prevention, pathophysiology, and treatment of gestational diabetes.
Language spoken Hindi. Diagnosis of Prediabetes is like the warning sign on the road. It warns one of the impending dangers. That is the best opportunity for the patient to control not only the blood sugar levels but also address other related issues that may lead to a heart attack in the future. Learn what prediabetes is. What can you do to prevent occurrence of full blown diabetes in the future. Cure for diabetes has always attracted the diabetics into buying different products. Whether diabetes is curable or not depends on what you mean by the word 'cure'? Many are duped into buying cures for diabetes. Learn what is really meant by cure of diabetes. How and why companies claim that they have cure for diabetes. Then make an intelligent informed decision on spending your money. Also in our opinion now is the best time to live a life as good as a non diabetic. Now we have the means, the understanding and the information on diabetes that we never had before. You as a diabetic will need to take the final step. This DVD will make you understand that how can you now live a life as healthy and as long as a non-diabetic or even better. Approximate running time: 45 minutes.
Wound Healing, Tissue Repair and Regeneration in Diabetes explores a wide range of topics related to wound healing, tissue repair and regeneration, putting a special focus on diabetes and obesity. The book addresses the molecular and cellular pathways involved in the process of wound repair and regeneration. Other sections explore a wide spectrum of nutritional supplements and novel therapeutic approaches, provide a comprehensive overview, present various types of clinical aspects related to diabetic wounds, including infection, neuropathy, and vasculopathy, provide an exhaustive review of various foods, minerals, supplements and phytochemicals that have been proven beneficial, and assess future directions. This book is sure to be a welcome resource for nutritionists, practitioners, surgeons, nurses, wound researchers and other health professionals.
Don't just survive - thrive! That's the message of this state-of-the-art guide to diabetes management. From causes, symptoms and side effects to treatments and diet, this book will help British diabetics understand all types of diabetes and delivers sound advice on staying fit and feeling great. The best-selling second edition has been updated to cover key information on managing pre-diabetes, plus new content on screening tests, medications and lifestyle advice. With additional information on the latest advances in therapy for diabetes and its complications, this new edition will make sure you're covered from every aspect.
By 2030, diabetes will be the 7th leading cause of premature mortality worldwide, according to the World Health Organisation. The application of nanotechnology in medicine holds many possible advantages and over the past few decades, there has been huge progress in its utilisation. Nanotechnology is widely applied for cancer treatment and other diseases but, the use of it for diabetes treatment is now starting to flourish. This book presents the latest developments of nanomedicine for the treatment of different facets of diabetes and related disorders. With a multidisciplinary approach, chapters focus on previously overlooked topics in glucose sensing, insulin delivery and secretion, bioimaging and transplantation of islets. This book is suitable for researchers of nanomedicine, nanotechnology and diabetes looking into the emergence of new approaches for the treatment of this life-threatening disease. |
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