This book on the metabolic aspects of polycystic ovary syndrome (PCOS) reviews the scientific evidence for the key etiological role of insulin resistance in the pathogenesis of PCOS. It also presents a new clinical and diagnostic approach and clearly explains the value of insulin-sensitizing agents, or "insulin sensitizers," in reducing hyperandrogenism and improving fertility outcome. Detailed information is provided on the use of insulin sensitizers such as metformin and inositol and suitable therapeutic protocols are described. All too often, PCOS is treated by gynecologists only as an endocrine disorder, without recognition of the very important part that insulin plays in the syndrome. Practitioners will find this book to be a valuable source of information on PCOS as a metabolic syndrome and a comprehensive guide to achieving good treatment results.

Diabetes and Wellbeing presents a range of effective psychological principles proven to positively impact the emotional wellbeing of individuals with type 1 and 2 diabetes. The guide takes an explicitly CBT approach to motivate sufferers in essential self-care tasks. * Written in a practical style, for those newly diagnosed with diabetes, individuals managing its challenges for many years, and healthcare professionals * Reveals how the stress of daily diabetes management can affect an individual s ability to stay motivated and engaged in essential self-care tasks that are vital for good health * Presents proven techniques for improving emotional wellbeing * First book to take an explicitly CBT approach to diabetes, simultaneously drawing on solution-focused behavioural therapy and mindfulness approaches * Fills the gap information of this kind among healthcare professionals and individuals with diabetes

Practical Diabetes Care for Healthcare Professionals, Second Edition, helps healthcare professionals get up-to-speed on type 2 diabetes care. Type 2 diabetes is multifaceted, affecting a person's daily life, family and workplace. Beyond the usual health impact, diabetes may also carry significant psychological burdens. Successful care means whole [person] care which can be daunting for an individual healthcare provider. The complete assessment of people with diabetes must include a review of diabetes medications, blood glucose levels, nutritional intake, physical activity, and stress. Also important is a review of possible micro- and macrovascular complications. This practical guide translates research and evidence-based recommendations into everyday clinical practice, with the goal of helping all members of the healthcare team more effectively manage their diabetic patients.

This book will interest practitioners and researchers in the food science and nutrition fields, and possibly others with an interest in the interaction between diet and health. There have been considerable advances in scientific techniques in the last few decades and these have been used to examine the composition and applications of traditional cures. Modern science has also seen the investigation of herbs, spices and botanicals beyond their traditional usage. The evidence-based approach that the Editors propose is relatively rare for this type of topic.

This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally. For each operation, indications, the surgical technique, potential complications, and the outcomes with respect to weight and obesity-associated comorbidities are presented. In view of the significant failure rate revealed by studies on the long-term results of bariatric surgery, the problem of weight regain and revision surgery are also discussed in detail, covering the different types of revision, conversion to other procedures, and the main outcomes. In addition, individual chapters focus on selected topics of importance. The role of bariatric surgery in the cure of type 2 diabetes ("diabetes surgery") is discussed and the debate over the significance of gastroesophageal reflux disease and hiatal hernia for choice of procedure is summarized. Finally, the most common endoluminal procedures, which have been gaining in importance, are described and other bariatric operations, outlined.

100 simple lifestyle changes you can make right now to prevent Type 2 diabetes and reverse a pre-diabetic diagnosis in an easy-to-use, user-friendly handbook. There are currently 84 million people in the United States living with a prediabetes diagnosis-left untreated, prediabetes can turn into full Type 2 diabetes within 5-10 years. While being told you are prediabetic can be scary, Healthy Habits for Managing and Reversing Prediabetes shows you 100 simple habits that you can implement in your daily life to lower your risk of developing diabetes. Healthy Habits for Managing and Reversing Prediabetes is packed with easy, straightforward tips to help you stop diabetes in its tracks. The secret? It's all about lifestyle changes-from eating less fat to incorporating more vegetables into your diet to exercising 150 minutes per week. This handbook will show you how easy it is to apply these changes and many more into your routine to live a full, happy, and healthy life. These simple modifications could be the difference between a healthy diabetes-free life and a diabetes diagnosis. You can control your fate-start now.

Diabetes Mellitus (DM, commonly referred to as diabetes, is a metabolic disorder in which there are high blood sugar levels over a prolonged period. Lack of sufficient insulin causes presence of excess sugar levels in the blood. As a result the glucose levels in diabetic patients are more than normal ones. It has symptoms like frequent urination, increased hunger, increase thirst and high blood sugar. There are mainly three types of diabetes namely type-1, type-2 and gestational diabetes. Type-1 DM occurs due to immune system mistakenly attacks and destroys the beta-cells and Type-2 DM occurs due to insulin resistance. Gestational DM occurs in women during pregnancy due to insulin blocking by pregnancy harmones. Among these three types of DM, type-2 DM is more prevalence, and impacting so many millions of people across the world. Classification and predictive systems are actually reliable in the health care sector to explore hidden patterns in the patients data. These systems aid, medical professionals to enhance their diagnosis, prognosis along with remedy organizing techniques. The less percentage of improvement in classifier predictive accuracy is very important for medical diagnosis purposes where mistakes can cause a lot of damage to patient's life. Hence, we need a more accurate classification system for prediction of type-2 DM. Although, most of the above classification algorithms are efficient, they failed to provide good accuracy with low computational cost. In this book, we proposed various classification algorithms using soft computing techniques like Neural Networks (NNs), Fuzzy Systems (FS) and Swarm Intelligence (SI). The experimental results demonstrate that these algorithms are able to produce high classification accuracy at less computational cost. The contributions presented in this book shall attempt to address the following objectives using soft computing approaches for identification of diabetes mellitus. Introuducing an optimized RBFN model called Opt-RBFN. Designing a cost effective rule miner called SM-RuleMiner for type-2 diabetes diagnosis. Generating more interpretable fuzzy rules for accurate diagnosis of type2 diabetes using RST-BatMiner. Developing accurate cascade ensemble frameworks called Diabetes-Network for type-2 diabetes diagnosis. Proposing a Multi-level ensemble framework called Dia-Net for improving the classification accuracy of type-2 diabetes diagnosis. Designing an Intelligent Diabetes Risk score Model called Intelli-DRM estimate the severity of Diabetes mellitus. This book serves as a reference book for scientific investigators who need to analyze disease data and/or numerical data, as well as researchers developing methodology in soft computing field. It may also be used as a textbook for a graduate and post graduate level course in machine learning or soft computing.

This book combines the reference material of a nephrology textbook with the everyday relevance of a clinical handbook. This second edition develops and expands upon the success of the first. All the content has been updated and entirely new chapters on acid-base disorders and stone disease have been added. Understanding Kidney Diseases includes over 60 real-life case studies and is illustrated with over 200 figures. Readers can test their knowledge with a bank of multiple-choice questions and put it into practice by answering questions that patients frequently ask. The book provides all that students, residents and fellows need in order to approach a patient with a kidney problem with confidence.

This book unravels the role of Point-of-Care (POC) glucose monitoring as an essential part of diabetes management. It provides the reader with an in-depth knowledge and understanding of diabetes management, including: the need for POC glucose monitoring the glucose detection technologies (invasive, noninvasive and continuous) being used in the POC devices the analytical performance, characteristics, pros and cons of the POC devices developed to date the importance and role of glycated hemoglobin (HbA1c) monitoring for diabetes management the various POC devices and analyzers for the determination of HbA1c. This is the first book to provide complete up-to-date information on POC glucose detection technologies and devices for diabetic monitoring and management. It will be an important reference for healthcare professionals, biomedical engineers, researchers, economists and policy makers. This book also serves as an asset and teaching aid for professionals and researchers in diabetic monitoring and management.

It is possible to manage and even reverse diabetes through natural means, and in "Reversing Diabetes," Dr. Colbert shows you how. Most people view diabetes as a dead-end street. Once you receive a diabetes diagnosis, your only option is to manage the symptoms with a restricted diet, close monitoring of blood sugar, and expensive medications. Dr. Colbert shows that diabetes can be treated instead through safe, natural means, like healthy food and vitamins rather than strictly relying on prescription drugs. He shows you how to manage your weight and your glucose intake with a whole-body approach, using nutritional supplements along with dietary and lifestyle changes to lose weight, repair cell damage, improve insulin function, and reduce the side effects from prescription drugs, many of which rob nutrients from the body and cause additional symptoms.
Based on the same life-changing principles of the low-glycemic, high-fiber eating plan provided in Dr. Colbert's "New York Times "best-selling book, "Dr. Colbert's "I Can Do This" Diet," this book adapts that plan in a way that makes it ideal for diabetics who need to manage their glucose levels and their weight. "Siloam, an imprint of Charisma House Book Group, is the leader in the Christian health and fitness genre, with several best-sellers...including Don Colbert's The Bible Cure series." --"Christian Retailing" "Physician Don Colbert Preaches The Gospel Of Good Nutrition, Advising His Patients To Follow In The Footsteps Of One Of History's Better-known Role Models." --"Orlando Sentinel"

The incidence and severity of diabetes mellitus is increasing worldwide, presenting a significant burden to society both in economic terms and overall well-being. Fortunately, time-tested anti-diabetes mellitus plant foods exist that are safe and could be effective in addressing this condition when consumed judiciously with a concomitant change in lifestyle. Plants with Anti-Diabetes Mellitus Properties presents an exhaustive compilation of the anti-diabetes mellitus activities of more than 1000 plants occurring worldwide. The author provides a brief botanical description, distribution, pharmacological properties, and phytochemicals, where appropriate. A list of traditional medicinal plants used to treat diabetes, but not tested for anti-diabetic activity, is also given. This unique reference highlights anti-diabetes mellitus plant foods along with a list of the edible parts of plants with anti-diabetes mellitus properties. Anti-diabetes mellitus nutraceuticals are described with guidelines for the development of food supplements and formulations of diets appropriate for diabetic patients. This is a valuable source of information for researchers, students, doctors, diabetic patients, and other individuals wanting to learn more about plant-based treatments for diabetes mellitus.

Women have long needed a book devoted to their unique issues with diabetes. This up-to-date and practical guide advocates simple lifestyle changes that can help women reduce their risk of getting diabetes or, if already diagnosed, prevent the disease's most serious complications. "Every Woman's Guide to Diabetes" translates the latest findings from diabetes research into proven strategies busy women can use to stay healthy and gain control over an often overwhelming disease. The authors discuss the nature of diabetes, helping readers through the complex medical decisions involved in diabetes treatment. They highlight strategies to decrease the emotional stress and social isolation that often accompany diagnosis, and offer everyday techniques for managing blood sugar.

Key features include: unique aspects of diabetes for women throughout the life cycle timetable of recommended tests and check-ups guide to medications with common dosages charts to help organize diabetes-care tasks and supplies time-management tips for better disease regulation guide to contraceptives available to women with diabetes review of issues critical to women before, during, and following pregnancy advice for overcoming barriers to weight loss and exercise plan for intelligent diet trade-offs while still enjoying meals practical tips for planning exercise strategies to avoid diabetes "burn-out"

Written by two physicians, one of whom is a woman living with diabetes, and an experienced medical writer, "Every Woman's Guide to Diabetes" recognizes the power that women have in their households to effect lifestyle changes that will benefit themselves and loved ones, including their mothers, daughters, sisters, and partners. This power can reduce the toll of the diabetes epidemic.

This comprehensive volume covers all aspects of nutrition in different scenarios of maternal diabetes, including the Type 1 or Type 2 diabetic mother, gestational diabetes, and postpartum diabetes. The volumes offer a comprehensive, yet thorough, overview of the subject, from the prevalence, risk factors, and insulin requirements of the mother; to possible outcomes and effects on the infant; to dietary advice in general and specific scenarios; and information on macro and micronutrient supplements. There is also a special section on international perspectives on maternal diabetes, with ten chapters that each focus on a different country. Nutrition and Diet in Maternal Diabetes: An Evidence-Based Approach offers an overview of the Type 1 and type 2 diabetic mother, maternal and offspring aspects of gestation diabetes, and breastfeeding and maternal gestational diabetes.

Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin resistance is a hallmark of pre-diabetes and type 2 diabetes mellitus, and is characterized by impaired insulin- signaling transduction. Authoritative and comprehensive, Lipoproteins in Diabetes Mellitus details the many changes wrought by insulin resistance and diabetes mellitus on lipid and lipoprotein metabolism. The book begins by summarizing the various techniques to measure lipoproteins and their subclasses. The mechanisms by which insulin resistance and diabetes mellitus increase risk for atherosclerosis, diabetic retinopathy, and diabetic nephropathy are then explored in detail. Finally, the effects of lifestyle modification and the results of clinical trials using established and investigational drugs are discussed. An invaluable contribution to the literature, Lipoproteins in Diabetes Mellitus is a comprehensive reference on the clinical and scientific aspects of lipoproteins in diabetes. It will have a long-lasting and significant effect on the medical management of people with diabetes.

Diabetes is a chronic disease involving self-management by the patients. This book teaches providers the skills to translate and transfer complex medical information to empower patients to participate in making well-informed decisions about their own care on a daily basis, as directed by the American Diabetes Association. It provides the basic knowledge around the pathophysiology of diabetes, different management options including insulin management and calculations, information on how foods affect blood sugars and how to address cardiovascular risk factors. This book aims to change clinical outcomes through its unique presentation of information and its approach to awareness. Key Features Follows a unique approach in imparting techniques that bring long-term patient behaviour changes, making the provision of chronic disease management more efficient and satisfying Serves to help professionals in their day-to-day patient management to achieve better outcomes Addresses the area of need for primary care and helps to make well-informed decisions by understanding the essential cost of care

Pancreas transplantation has rapidly moved from an experimental procedure associated with high rates of morbidity and mortality to a mainstream technique with excellent patient and graft survival. Over 30,000 pancreas transplants have already been performed. The value of pancreas transplantation however must be balanced against the risk of the operative procedure and the innovative long-term immunosuppressive therapy. The indications for this procedure and the selection of the patients are critical to ensure low mortality and any improvements in quality of life.
This second edition reflects recent advances in the field, especially the increasing number of islet transplantations and the growing interest in stem cell research applicable to this condition. It provides an authoritative account on the current status of the whole organ pancreas transplantation and islet and pancreatic stem cell transplantation.

This education tool covers how insulin works in the body, types of insulin and treatment plans, and how to calculate mealtime insulin and correction insulin. Clients will also learn about testing patterns to check insulin doses along with the signs, symptoms, and treatment of hypoglycemia. An insulin dosing worksheet is provided for the diabetes educator to personalize a client's blood glucose target and insulin plan, and it shows a stepwise approach for calculating mealtime insulin. This booklet is an excellent follow-up to Choose Your Foods: Count Your Carbs.

Diabetes Digital Health brings together the multifaceted information surrounding the science of digital health from an academic, regulatory, industrial, investment and cybersecurity perspective. Clinicians and researchers who are developing and evaluating mobile apps for diabetes patients will find this essential reading, as will industry people whose companies are developing mobile apps and sensors.

Global Health Complications of Obesity presents a valuable resource for research scientists and clinicians by covering the burden of obesity and related diseases and serving as a starting point for in-depth discussions in academic settings and for obesity-treatment specialists. Obesity is associated with a statistically higher risk of heart disease, hypertension, insulin resistance, type 2 diabetes and many other diseases. This succinct resource focuses on the current data, research and management of obesity. It is essential reading for healthcare professionals, endocrinologists, nutritionists, public health students and medical students.

This issue of Physician Assistant Clinics, Guest Edited by Kim Zuber, PA-C and Jane S. Davis, CRNP, DNP, is devoted to Diabetes. Articles in this outstanding issue include: A Century of Discovery: The Centennial of Insulin; What it is and How we know: Diabetes in the 21st Century; The Ominous Octet and other Scary Diabetes Stories; Putting the Diabetes Patient in Charge; Diabetes: Counting Carbs Instead of Pennies; Non-insulin Therapy for Diabetes; Pens and Needles: Insulin Therapy for Diabetes; Managing Diabetes in the Digital Age; When Crisis Strikes: The acute complications of diabetes; Living Day to Day: Chronic Complications in Diabetes; Sugar Babies: Diabetes in the Pediatric Population; And Baby Makes 2: Gestational Diabetes; The Boomers Come of Age: Elderly and Frail Diabetes Patients; The Rising Price of Sugar; and The Future of Diabetes. A CME program is also available to subscribers of Physician Assistant Clinics.

Stem Cell Therapy for Diabetes, one of the latest installments of the Stem Cell Biology and Regenerative Medicine series, reviews the three main approaches for generation of sufficient numbers of insulin-producing cells for restoration of an adequate beta-cell mass: beta-cell expansion, stem-cell differentiation, and nuclear reprogramming. Adeptly collecting the research of the leading scientists in the field, Stem Cell Therapy for Diabetes compares the merits of employing autologous versus banked allogeneic cell sources for generation of surrogate beta cells, and addresses tissue engineering and ways for cell protection from recurring autoimmunity and graft rejection. Stem Cell Therapy for Diabetes provides essential reading for those especially interested in tracking the progress in applying of one of the most exciting new developments in bio-medicine towards a cure for diabetes.

This issue of Endocrinology and Metabolism Clinics, guest edited by Dr. Grazia Aleppo, will cover key topics in Technology in Diabetes. This issue is one of four selected each year by our series consulting editor, Dr. Adriana G. Ioachimescu. Topics discussed in this issue will include: Evolution of Diabetes Technology, Diabetes Technology in children, Diabetes Technology in adults with type 1 and type 2 Diabetes, Benefits and challenges of Diabetes Technology use in older adults, Integration of Diabetes Technology in Clinical Practice, Diabetes Technology in the inpatient setting for management of hyperglycemia, Standardization of CGM reports, Diabetes Technology and Exercise, Psychosocial Aspects of Diabetes Technology use, Automated insulin delivery, and Glucagon, among others.

The traditional agents for controlling the levels of glucose in the blood remain important therapies but they have their downside from the point of view of tolerability and side effects. Moreover, they appear not to be able to counter the natural history deterioration of the disease in terms of the onset of diabetic-related complications.

Recent years have seen an influx of new treatment therapies and technologies aimed at achieving better glycaemic control for diabetic patients such as liraglutide (Novo Nordisk) and saxagliptin (BMS/Astra-Zeneca) and insulin pumps, away from the more traditional therapies used (classic insulin therapy, oral hypoglycaemics).

This book outlines these new technologies/treatments by collating the best journal articles published in the last year, and providing expert analysis on each one.

Advanced Technologies and Treatment for Diabetes 3E brings together and critically analyses the last year's most important articles published in the world's leading medical journals on this topic. Chapters are focused on the most current hot topic areas such as: new methods of insulin delivery; internet and IT use in treatment of diabetes; bariatric surgery & diabetes; and immunotherapy for type 1 diabetes.

Each chapter includes abstracts of the published articles, scientific conclusions made, as well as annotations and a comments and analysis section from the relevant chapter editor, each of which being a well-known expert in the field.

All researchers in the fields of diabetes, endocrinology and metabolism will find this book extremely useful, as will diabetes technology developers, and specialist endocrinologists involved with the care of diabetic patients.

With the increasing incidence of Type 2 diabetes in the adult population and the realization that this is a vascular disease and a major coronary risk factor, Professor Betteridge has chosen fifty diabetologists to contribute a case which has had an effect on their clinical practice. Both Types 1 and 2 diabetes are included, along with other forms of diabetes, eg gestational. Each case is presented in the same format. The various cases are informative and educational and should provide the reader with a sounder knowledge of patient and disease types.

Adopting an anthrozoological perspective to study the participation of non-human animals in regimes of care, this book examines the use of canine scent detection to alert 'hypo-unaware' individuals to symptoms of human chronic illness. Based on ethnographic research and interviews, it focuses on the manner in which trained assistance dogs are able to use their sense of smell to alert human companions with Type 1 diabetes to imminent hypoglycaemic episodes, thus reducing the risk of collapse into unconsciousness, coma or, at worst, death. Through analyses of participant narrations of the everyday complexities of 'doing' diabetes with the assistance of medical alert dogs, the author sheds light on the way in which each human-canine dyad becomes acknowledged as a team of 'one' in society. Based on the concept of dogs as friends and work colleagues, as animate instruments and biomedical resources, the book raises conceptual questions surrounding the acceptable use of animals and their role within society. As such, this volume will appeal to scholars across the social sciences with interests in human-animal interactions and intersections. It may also appeal to healthcare practitioners and individuals interested in innovative multispecies methods of managing chronic illness.