This book covers the main fields of diabetes management through applied technologies. The different chapters include insulin therapy through basic insulin injection therapy, external and implantable insulin pumps and the more recent approaches such as sensor augmented pumps and close-loop systems. Islet transplantation is also described through its technical aspects and clinical evaluation. Glucose measurement through blood glucose meters and continuous glucose monitoring systems are comprehensively explained. Educational tools including videogames and software dedicated to diabetes management are depicted. Lastly, Telemedicine systems devoted to data transmission, telemonitoring and decision support systems are described and their use for supporting health systems are summarized. This book will help professionals involved in diabetes management understanding the contribution of diabetes technologies for promoting the optimization of glucose control and monitoring. This volume will be helpful in current clinical practice for diabetes management and also beneficial to students.

This book comprehensively discusses both gestational diabetes and diabetes that pre-exists pregnancy (type 1 or type 2), highlighting conditions and complications that are expected to occur during and after pregnancy. The book focuses on clinical problems encountered in everyday practice, but also covers topics that contribute to a better understanding of the clinical issues (genetics, epigenetics, pathophysiology). Written by leading experts in various disciplines, the chapters draw on the authors' experience to critically evaluate relevant data on diagnosing and treating the disease and provide guidance on the optimal approach in each specific situation as well as on how to decide between alternatives. A series of learning objectives, tables, figures, algorithms and illustrations increase the book's readability and help readers improve their understanding of the material. This book serves as a practical and useful tool for general obstetricians, fetal-maternal specialists, endocrinologists, diabetologists, neonatologists, midwives and for anyone involved in the management of pregnant women with this condition.

The world is faced with an epidemic of metabolic diseases such as obesity and type 2 diabetes. This is due to changes in dietary habits and the decrease in physical activity. Exercise is usually part of the prescription, the first line of defense, to prevent or treat metabolic disorders. However, we are still learning how and why exercise provides metabolic benefits in human health. This open access volume focuses on the cellular and molecular pathways that link exercise, muscle biology, hormones and metabolism. This will include novel "myokines" that might act as new therapeutic agents in the future.

Sirtuin Biology in Cancer and Metabolic Disease: Cellular Pathways for Clinical Discovery offers a compelling and thought-provoking perspective for the examination of the intriguing biology of sirtuins that ties cancer and metabolic disease together and provides a critical platform for the development of sirtuin-based novel therapeutic strategies to effectively treat cancer and metabolic disorders with precision in order to minimize any potentially detrimental clinical outcomes. An exciting prospect for the development of innovative therapeutics for cancer and metabolic disorders involves sirtuins. Sirtuins are histone deacetylases that have an intricate role in the onset and development of cancer and metabolic disease. Implementing a translational medicine format, this innovative reference highlights the ability of sirtuins to oversee critical pathways that involve stem cell maintenance, cellular proliferation, metabolic homeostasis, apoptosis, and autophagy that can impact cellular dysfunction and unchecked cellular growth that can occur during cancer and metabolic disease. Each chapter offers an intuitive perspective of advances on the application of sirtuin pathways for cancer and metabolic disease that will be become a "go-to" resource for a broad audience of scientists, physicians, pharmaceutical industry experts, nutritionists, and students.

This education tool covers how insulin works in the body, types of insulin and treatment plans, and how to calculate mealtime insulin and correction insulin. Clients will also learn about testing patterns to check insulin doses along with the signs, symptoms, and treatment of hypoglycemia. An insulin dosing worksheet is provided for the diabetes educator to personalize a client's blood glucose target and insulin plan, and it shows a stepwise approach for calculating mealtime insulin. This booklet is an excellent follow-up to Choose Your Foods: Count Your Carbs.

Insulin pump therapy is now a well-established option for treating diabetes. This method of insulin delivery offers the opportunity for people with diabetes to manage their diabetes confidently and competently to achieve good glycaemic control and a better quality of life. "Using Insulin Pumps in Diabetes" covers all aspects of insulin pump therapy in a clear and informative style, and is an essential guide for all health professionals involved in caring for people with diabetes using insulin pumps.

"Using Insulin Pumps in Diabetes" explores issues such as the advantages and disadvantages of insulin pump therapy; the experiences of insulin pump users, how to set up an insulin pump service, how to set and adjust insulin doses and optimising glycaemic control. It also includes chapters on insulin pumps in pregnancy, and in babies, toddlers and young children.

The book explores both the clinical presentation of serious diabetic emergencies (like ketoacidosis, hyperosmolar coma, and severe hyper and hypoglycemia) that consultants and hospital staff encounter in practice and the best methods of both managing the emergencies and also administering follow-up guidance/care. All chapters are clearly structured to highlight: definition of emergency; epidemiology; potential causes, diagnosis, clinical management (including problem areas), follow-up management/care; and patient advice.
There are case studies to aid clinical understanding, as well as 5-7 multiple choice questions and several key points/take-home message boxes in every chapter.

Adopting a truly global perspective and a practical approach to diabetes-including pathophysiology, genetics, regional peculiarities, management, prevention and best practices-this book is an excellent resource for clinicians and policy-makers working with patients in more austere settings. The global prevalence of diabetes is estimated to increase from 422 million in 2014 to 592 million in 2035. Sadly, low- and middle-economy countries are projected to experience the steepest increase, but even in developed economies, vulnerable demographic subgroups manifest disparities in diabetes prevalence, quality of care, and outcomes. This book extends coverage to those underserved and minority communities in the developed world. In a consistent chapter format, it discusses classification, pathophysiology, genomics, diagnosis, prevention and management of diabetes in economically challenged regions as well as underserved populations in affluent nations. Suggestions regarding future directions in the organization of diabetes care delivery, prevention and research priorities are also provided. The detailed identification of barriers to optimal care and the practical approach to the management and prevention of diabetes make Diabetes Mellitus in Developing Countries and Underserved Communities a valuable resource for clinicians, researchers and health policy leaders.

A clinically-focused handbook that provides an overview of the different types of insulin, delivery methods, emerging treatments, and cutting-age devices. The aim of the handbook is to discuss insulin treatment strategies that can improve glucose control, enhance patient adherence, and minimize adverse effects and disease-related complications. Concise scope and size is ideal for busy healthcare professionals that regularly encounter patients with diabetes and require an up-to-date snapshot of advances in diabetes care.

What if you could not only manage your diabetes, but actually reverse it? The Reverse Your Diabetes Diet takes a fresh approach to managing type 2 diabetes. Based on the latest research, this book will provide you with the information you need to modify your diet and achieve stable control of blood glucose levels. Including 60 easy-to-prepare recipes, covering breakfasts, snacks, main meals and even desserts, this book is the perfect guide to nutrition for anyone with type 2 diabetes. With meal plans, food lists and healthy alternatives to your favourite foods, you'll find new ideas for what to make from the ingredients in your shopping basket. Written by diabetes expert Dr David Cavan and in association with diabetes.co.uk, the UK's largest online diabetes community, Reverse Your Diabetes Diet will help you to take control of your diabetes and live healthily for good.

A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods.

Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006

Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced - and are being developed further - that facilitate monitoring of metabolism and even diagnosis of certain defects in human metabolism. While some of these methods are restricted to research facilities, others are already used in clinical practice. The correct beneficial use of these methods requires knowledge of the nature of the techniques and their clinical relevance.

"Clinical Diabetes Research: Methods and Techniques" provides summaries of established state-of-the art-techniques and introduces the new technologies, evaluating their potential in clinical diabetes research. One section compares the efficacy of all metabolic tests that measure insulin action. Another section describes methods that allow quantification of whole body and intracellular metabolic fluxes relevant to diabetes research. The final section focuses on the planning and pitfalls of clinical studies in the field of metabolism. Each chapter throughout the book combines the theoretical basis of the approach with practical recommendations. There are further chapters on the design of clinical trials and ethical considerations.

The publication is timely in view of the impressive development of the methods and techniques with their application to understanding the pathophysiology of diabetes, insulin resistance syndromes, obesity, and the metabolic effects of treatment.

"Clinical Diabetes Research: Methods and Techniques" is of great relevance for researchers (from students and post-docs to principal investigators) in the field of human metabolism, clinical endocrinologists and diabetologists who are involved in clinical studies.

Every year many patients suffer serious side effects of low blood sugar. These range from passing out to seizures, permanent brain damage, stroke and even death. All this happens because these diabetics did not fully know how to recognise and manage their low blood sugars. They thought that they knew it because they attended that few hours of training on diabetes or because they read the article on the web. Well it did not work for them. You have an opportunity to be better prepared. This is not a matter to be taken lightly and cannot be learnt in a few minutes. This one hour presentation educates you to identify and correctly treat the lows or low blood sugars in diabetes so that one can avoid serious life threatening problems. Approximate running time: 50 minutes.

Before the discovery of insulin, a diagnosis of Type 1 diabetes was a death sentence. One hundred years after a milestone medical discovery, 'Insulin - The Crooked Timber' tells the story of how insulin was transformed from what one clinician called 'thick brown muck' into the very first drug to be produced using genetic engineering, one which would earn the founders of the US biotech company Genentech a small fortune. Yet when Canadian doctor Frederick Banting was told in 1923 that he had won the Nobel Prize for this life-saving discovery, he was furious. For the prize had not been awarded to him alone - but jointly with a man whom he felt had no right to this honour. The human story behind this discovery is one of ongoing political and scientific controversy. Taking the reader on a fascinating journey, starting with the discovery of insulin in the 1920s through to the present day, 'Insulin - The Crooked Timber' reveals a story of monstrous egos, toxic career rivalries, and a few unsung heroes such as two little known scientists whose work on wool fibres, carried out in a fume-filled former stable, not only proved to be crucial in unravelling the puzzle of insulin but ushered in a revolution in biology. It was the author's own shocking diagnosis with Type 1 diabetes that prompted him to sit down and write this book, but this story has lessons for us all about what technology can - and more importantly cannot - do for us. As the world pins its hopes on effective and lasting vaccines against Covid-19, these lessons from the story of insulin have never been more relevant.

This innovative new guide to the diabetes technology introduces both insulin pumps and continuous glucose monitoring to the range of healthcare professionals involved in diabetes care. It is the first book of its kind and covers the principles and step by step implementation of state of the art devices to support people with diabetes. With interactive clinical cases and worked examples it will prove to be an invaluable, practical guide. It will also prove highly informative for diabetes patients. Complete, up-to-date guide to insulin pump initiation and getting the most out of pump therapy A clear framework for systematic interpretation and making the best use of continuous glucose monitoring data Tips for managing challenging glucose patterns including exercise, alcohol and fasting BONUS access to the complete downloadable eBook version on Expert Consult Complete, up-to-date guide to insulin pump initiation and getting the most out of pump therapy A clear framework for systematic interpretation and making the best use of continuous glucose monitoring data Tips for managing challenging glucose patterns including exercise, alcohol and fasting BONUS access to the complete downloadable eBook version on Expert Consult (with print edition)

The original Dr. Neal Barnard's Program For Reversing Diabetes is one of Rodale's strongest backlist sellers with nearly two hundred thousand copies sold since 2006 and several hundred copies continuing to be sold per month. By following Dr. Barnard's revolutionary plan, readers have been able to cut back on or eliminate medications and reduce the risk of complications, while experiencing weight loss, increased energy, and a new lease on life. Before Dr. Barnard's scientific breakthrough, most health professionals believed that once you developed diabetes, you were stuck with it - and could anticipate one health issue after another, from worsening eyesight and nerve symptoms to heart and kidney problems. But as Dr. Barnard's groundbreaking work has revealed, this simply is not true. Dr. Barnard has shown that it is often possible to improve insulin sensitivity and tackle type 2 diabetes by following his step-by-step plan, which includes a healthful vegan diet with plenty of recipes to get started, an exercise guide, advice about taking supplements and tracking progress, and troubleshooting tips. The scientifically proven, life-changing program introduces a style of eating that will improve how people with type 2 diabetes respond to insulin, addressing the defining symptom of diabetes and allowing people with diabetes to control blood sugar more effectively than with conventional dietary regimens for people with diabetes.

Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.

Highly Commended in the 2004 BMA Medical Book Competition (Endocrinology)

Judges' summary:
"Beautifully and clearly written to appeal to all levels of healthcare professional knowledge. A wealth of practical experience is freely donated to the reader in a friendly and accessible way. Each section is easily found and any member of the team could care for a patient with that particular problem to a high standard with this book in their hand. I would unhesitatingly recommend to all diabetes doctors - both senior and junior, and every diabetes unit should have a copy. This new edition is excellent and should be considered for an award."

"Diabetes and its Management," Sixth Edition, continues to provide a practical clinical guide to the management of patients with diabetes. The author team has been expanded and now also includes a Nurse Practitioner specialising in diabetes to provide the nursing perspective. It is a concise manual that distils the essential recent developments into practical advice.

Count your carbs and count on managing your diabetes Living with diabetes doesn't have to mean giving up all of your favorite foods. Carbs from healthy foods boost nutrition and supply essential fuel for your brain and body. Counting carbs is integral to managing diabetes because your carb choices, portion sizes, and meal timing directly impact blood glucose levels. Diabetes & Carb Counting For Dummies provides essential information on how to strike a balance between carb intake, exercise, and diabetes medications while making healthy food choices. Covering the latest information on why carb counting is important for Type 1 diabetes, Type 2 diabetes, and gestational diabetes, this book provides the tools you need to best manage your diet and your diabetes. Nearly one in 11 people in the United States have diabetes and one out of every 3 adults have prediabetes (blood glucose levels above normal ranges). Diabetes rates are skyrocketing worldwide. If you or a loved one has been diagnosed or is teetering on the edge of diagnosis you'll find all the safe, trusted guidance you need to better manage your health through improving your nutrition and managing your carb intake. * Discover how what you eat affects diabetes * Explore the importance of carbs in nutrition and health * Get the facts when it comes to fiber, fats, sweeteners, and alcohol. * Decipher food labels and discover how to count carbs in bulk, fresh, and restaurant foods * Manage your diabetes and reduce other diet-related health risks * Improve blood glucose levels * Sample meal plans in controlled carb count ranges * Food composition lists for counting carbs and identifying best bet proteins and fats If you're one of the millions of people with diabetes or prediabetes in search of an accessible resource to help you portion and count carbs to better manage this disease, this is the go-to guide you'll turn to again and again because when it comes to diabetes carbohydrates count.

The management of diabetes in children and young people continues to develop in important areas, including self-monitoring, insulin delivery, dietary prescription, concept of control and the early identification of complications. Meanwhile responsibility for care has become a partnership between patients, parents and a multi-disciplinary team of health professionals. Key features of Childhood and Adolescent Diabetes include:

• Stand-alone chapters offering practical solutions to problems confronting children, young people and their parents
• Rational advice on monitoring and managing diabetic complications
• Guidance on the involvement of families, schools and teachers
• Discussion of the psychological aspects
• Recommendations on setting standards of care, audit, data-handling and registration
• Suggestions for setting up and running activities beyond the clinic

Practical and accessible, this manual will be invaluable to all members of the diabetes specialist team working with children, including diabetic physicians, paediatricians, diabetic nurse specialists and dieticians. Other titles in the Wiley Practical Diabetes series: Diabetes and Pregnancy: An International Approach to Diagnosis and Management 1996 Anne Dornhorst and David R. Hadden (Editors) Diabetic Complications 1996 Ken M. Shaw (Editor) Prediction, Prevention and Genetic Counseling in IDDM 1995 Jerry P. Palmer (Editor) Diabetes in Old Age 1994 Paul Finucane and Alan J. Sinclair (Editors)

The indispensable guide to all aspects of clinical care, the Oxford Handbook of Endocrinology and Diabetes has been fully updated for its fourth edition, providing comprehensive coverage of both disciplines in a practical and concise format. Featuring new chapters on transition in endocrinology and diabetes, practical nursing considerations, and the genetics of endocrinology, and expanded sections on inherited endocrine syndromes and MEN, it retains the clear organisation and layout for ease of reference as the previous edition over a broader range of topics. Combining authority, relevance, and reliability, this title includes new therapies and guidelines alongside 'clinical pearl' and 'tricky situation' boxes to aide readers in rare or complicated situations. This is the must-have guide for all trainees and specialist nurses in endocrinology and diabetes.

Bestselling author Jordan Rubin, with David Remedios, M.D., shows how to adopt the 7 Keys in "The Great Physician's Rx for Health and Wellness" to focus aggressively on diabetes and develop a game plan against it.

The enormous increase in our knowledge and understanding of diabetes mellitus in recent years has resulted in new management strategies for greatly enhancing care in diabetic pregnancy. Clinicians responsible for the care of women with diabetes need to keep abreast of these advances. Diabetes and Pregnancy: An International Approach to Diagnosis and Management is a comprehensive, yet practical guide to the present state of knowledge regarding diabetic pregnancy. It summarizes published literature, and offers clear and valuable information on the practicalities of providing special care before, during and after pregnancy. This volume will be indispensable to all members of the health care team involved in the care of pregnant diabetic women and their babies, including obstetricians, neonatologists, diabetes physicians, specialist nurses, midwives as well as general practitioners.

This new edition of the popular and market-leading Diabetes in Old Age features up-to-date and comprehensive information about the key aspects of managing older people with diabetes, predominantly type 2 diabetes. With a strong evidence-based focus throughout, the entire range of issues surrounding diabetes and its many complications are covered, each with a clear focus on how they relate directly to the older patient. Varying approaches to optimizing diabetes care in the community, primary care and secondary care health care arenas are presented, and the importance of comprehensive functional assessment is emphasized. Coverage of areas unique to an ageing population of older people with diabetes such as falls management, frailty and sarcopenia, and cognitive dysfunction form a key cornerstone of the book. In every chapter, best practice points and key learning outcomes are provided, as well as published evidence bases for each major conclusion. Diabetes in Old Age, 4th edition is essential reading for diabetologists and endocrinologists, diabetes specialist nurses, primary care physicians, general physicians and geriatricians, podiatrists and dieticians with an interest in diabetes, as well as all health professionals engaged in the delivery of diabetes care to older people.

Diabetes is a complex disease and is also one of the most common. It is very difficult to reach an accurate estimate for the global prevalence of diabetes since the standards and methods of data collection vary widely in different parts of the world. In addition, many potential sufferers are not included in the count because according to an estimate about 50% of cases remain undiagnosed for up to 10 years. However, according to an estimate for 2010, globally, there are about 285 million people (amounting to 6.4% of the adult population) suffering from this disease. This number is estimated to increase to 439 million by 2030 if no cure is found. The general increase in life expectancy, leading to an ageing population, and the global rise in obesity are two main reasons for the increase.With the basic platform set, Editor presents his views and advice to the readers, especially to diabetic patients suffering from T2DM, on the basis of his observations and information collected from other diabetics.