Prevention and treatment of cardiometabolic disorders by lifestyle management is the most understood and effective applications of this emerging field. The focus of this book on prediabetes, diabetes and cardiometabolic diseases is timely and will be a welcome addition to clinicians who wish to gain more knowledge and competence in the area. This book will focus on the metabolic syndrome, which is the largest non-communicable disease of our time, and lifestyle approaches that drastically reduce the risks and adverse effects of this condition. Presents a detailed review of clinical evidence and guide for implementation. Provides a toolkit to counter both the high cost of medications and the need to address metabolic disorders associated with insulin resistance early, before or simultaneous to when medications are indicated.

This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson s disease and ALS combined, is a major source of disability to diabetic persons wordwide. The book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system.
*A volume in the Handbook of Clinical Neurology series, which has an unparalleled reputation as the world's most comprehensive source of information in neurology.
*International list of contributors including the leading workers in the field.
*Describes the advances which have occurred in clinical neurology and the neurosciences, their impact on the understanding of neurological disorders and on patient care."

This issue of Clinics in Geriatric Medicine, guest edited by Dr. Elsa S. Strotmeyer, is devoted to Medical Complications of Diabetes in Older Adults. Articles in this issue include: Glucose Dysregulation: Pathophysiology and Prevention; Diabetic Medications and Polypharmacy; Physical Function and Disability; Diabetes and Osteoarthritis; Adiposity, Muscle Mass, and Diabetes; Exercise and Weight Loss in Diabetes Management; Diabetes and Cognition; Diabetes and Depression; Sleep Apnea and Diabetes; Diabetes and Coronary Artery Disease; and Diabetes and Balance and Falls.

Diabetes in Cardiovascular Disease is a current, expert resource focusing on the complex challenges of providing cardiovascular care to patients with diabetes. Designed as a companion to Braunwald's Heart Disease, this interdisciplinary medical reference book bridges the gap between the cardiology and endocrinology communities of scientists and care providers, and highlights the emerging scientific and clinical topics that are relevant for cardiologists, diabetologists/endocrinologists, and the extended diabetes care team. Access essential coverage of basic and clinical sciences, complemented by an expanded focus on epidemiology, behavioral sciences, health policy, and disparities in health care. Take advantage of a format that follows that of the well-known and internationally recognized Braunwald's Heart Disease. Review the best available clinical data and pragmatic recommendations for the prevention and management of cardiovascular complications of diabetes; national/societal intervention strategies to curb the growing prevalence of diabetes; and the current pathophysiological understanding of cardiovascular comorbidities in patients with diabetes. Expert Consult eBook version included with purchase.

This book covers the most important clinical and bench science aspects of metabolic syndrome. It will be of value to all of those seeking a comprehensive update on the metabolic syndrome. Furthermore, it will provide a broad basis for advancing research in the multiple intersecting disciplines encompassed by the metabolic syndrome.

Diabetes mellitus is a disease with tremendous health and economic burden. A better understanding of how normal glucose homeostasis is maintained and the pathogenesis is important to identify new ways for diabetes treatment. This book addresses multiple aspects of this area of research.

Key features:

* Written by experts in the field * Informs on important topics related to the regulation of glucose homeostasis and the pathogenesis of diabetes mellitus, a field of intense research interest

Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency

Many of us, at the best of times, struggle for inspiration when it comes to cooking - and that's without a medical condition that may affect our eating habits and require careful management. The right diet is the foundation of a healthy lifestyle and all the more important for the successful management of diabetes. Fully updated for a UK audience Diabetes Cookbook For Dummies will include the latest dietary recommendations and medical information on diabetes and its management. Packed with over 100 delicious and easy to prepare recipes - for everyday eating and entertaining - alongside a brand new section on packing healthy lunches and picnics, this book will help make mealtimes interesting and healthy. The book also offers guidance on the glycaemic index, nutritional information, diabetic exchanges for each recipe and lifestyle advice to help readers take control of their condition and live life to the full. Diabetes Cookbook For Dummies will feature: Part I: Thriving with Diabetes* Living To Eat With Diabetes* Eating To Live With Diabetes* Planning Meals for Weight Loss Goals* Eating What You Like (Within Reason)* Stocking Up at the Supermarket Part II: Healthy Recipes That Taste Great* Enjoying the Benefits of Breakfast* Starting Well: Hors d'Oeuvres and First Courses* Sipping Simply Divine Soups* Taking a Leaf From the Salad Bar* Being Full of Beans (and Grains and Pasta)* Adding Veg to Your Meals* Boning Up on Fish Cookery* Flocking to Poultry* Creating Balanced Meals with Meats* Nibbling on Snacks* Drooling Over Mouth-Watering Desserts Part III: Eating Away from Home* Eating Out as a Nourishing Experience* Packing a Picnic Lunch Part IV: The Part of Tens* Ten (or So) Simple Steps to Change Your Eating Habits* Ten Easy Substitutions in Your Eating Plan* Ten Strategies to Normalize Your Blood Glucose* Ten Healthy Eating Habits for Children with Diabetes Part V: Appendixes* Appendix A: Investing in Food Supplements for Optimum Health* Appendix B: Exchange Lists* Appendix C: A Glossary of Key Cooking Terms* Appendix D: Conversions of Weights, Measures, and Sugar Substitutes* Appendix E: Other Recipe Sources for People with Diabetes

International experts from world-renowned medical schools comprehensively review for practicing clinicians and scientists alike the latest understanding of the epidemiology, causation, and consequences of diabetes and obesity. The authors discuss in detail their diagnosis, clinical manifestations, complications, and best practices for diagnosis and treatment. They also review the history and epidemiology of these conditions, explain their genetics and pathophysiology, and illuminate their known mechanisms and interactions. State-of-the-art survey-chapters critique current approaches (lifestyle and pharmacological) to the treatment of these conditions.

Over the past two decades, type 2 diabetes has emerged as a leading threat to global health, and the considerable overlap in obesity and diabetes trends are likely no coincidence. While the underpinnings for both etiologies are linked to lifestyles, particularly dietary and physical activity patterns, determining optimal approaches for preventing and managing type 2 diabetes using dietary composition remains a challenge. Nutrition and Type 2 Diabetes: Etiology and Prevention rigorously examines various perspectives on diet and type 2 diabetes. The book presents a comprehensive description and evaluation of the central research to date, primarily in humans, on the macronutrients and their subclasses, micronutrients, foods, beverages, and overall dietary patterns with respect to the risk of type 2 diabetes. It addresses the mediating/mechanistic role of obesity and body composition throughout the text where appropriate. The chapter authors, all leading researchers in the field, discuss fundamental nutritional principles applied to the pathophysiology of type 2 diabetes as well as applied behavioral studies on nutrition and diabetes for each subject area. The depth and breadth of this book includes aspects of the "food synergy" model for understanding the complicated pathways between nutrition, dietary habits, and risk for type 2 diabetes. It also examines the effects of artificially sweetened beverages and coffee. This reference provides a review of the science on the potential impact of many components of dietary behavior and nutritional properties on etiology and risk for this disease, knowledge that is essential for formulating informed approaches to public health progress in this area.

An unprecedented compilation of state-of-the-art advances in clinical research on diabetes and obesity by premier clinical scientists around the world. This volume critically reviews the limitations and strengths of today's major techniques in clinical diabetes research, and then reviews how those methods have been used to carry out cutting-edge studies of carbohydrate, lipid, and protein metabolism in the disease.

This book provides a concise, state-of-the art review of the surgical treatment of metabolic syndrome and diabetes mellitus. The volume reviews what current practices in surgery and metabolic syndrome and diabetes including the biohormonal effects of the different surgeries. Isolating the effects of the different procedures is critical to the decision tree for type of procedure selected for an individual patient. Specifically for diabetes, this textbook will provide a guide for practitioners to a tailored approach to the treatment. Areas of ongoing research that highlight the minimally invasive approach as well as incorporating what we know of the biochemical results of surgery are presented. Results of established weight loss procedures and ongoing trials are juxtaposed against some of the more novel techniques to ascertain a best practice. Metabolic Surgery and the Surgical Treatment of Diabetes serves as a very useful resource for physicians and researchers dealing with, and interested in, this rising epidemic of metabolic syndrome and diabetes. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts.

This new edition provides clinicians and trainees with the latest advances in the diagnosis and management of diabetes mellitus. Beginning with an overview of physiology, epidemiology, pathogenesis and classification, the next chapters discuss related issues such as nutrition, exercise and counselling. The following sections cover different aspects of the disease including emergency situations, therapeutic agents, and associated disorders including retinopathy, stroke, liver disease, and neuropathy. The final chapters examine diabetes in specific demographic groups such as in pregnancy, obesity, in the elderly and in childhood and adolescence. The eighth edition has been fully revised and includes new topics including new anti-diabetic drugs, recent clinical trials, and non-alcoholic fatty liver disease. The book is highly illustrated with clinical photographs, tables and boxes, and each chapter concludes with MCQs (Multiple Choice Questions) with answers, for self-assessment. Key points Eighth edition presenting latest advances in diagnosis and management of diabetes Fully revised, with many new topics added Features MCQs with answers for self-assessment Previous edition (9789351528531) published in 2015

Together, obesity and diabetes form a 21st century epidemic, the treatment of which consumes a substantial fraction of global health costs. New and improved therapies are therefore desperately needed.Incretins are short peptide hormones released from the gut in response to food transit. These hormones regulate a plethora of processes to control food intake, body weight and glucose homeostasis. This is one of the fastest areas of growth within diabetes research, and over the past decade, increasing numbers of novel diabetes drugs - many based on incretin action - have been added to the therapeutic armoury.Following an introduction detailing the historical perspective and discovery of incretin therapies and clinical applications, the book looks at the release of incretins at a cellular level from entero-endocrine cells, and actions on the pancreas (alpha and beta cells) and brain. It then looks at changes in incretins seen in diabetes and following bariatric surgery. Finally, the side effects of incretin therapy are discussed. Importantly, each chapter contains a methodology section aimed at providing a practical guide to key techniques in the field of incretin biology and ranges from basic laboratory research to clinical practice.Incretin Biology - A Practical Guide offers a unique perspective within this field of research by bringing together scientists, physicians and bariatric surgeons. Thus, it is a comprehensive text that offers a broad overview of the subject.

This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies. Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique. This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.

This issue of Endocrinology and Metabolism Clinics of North America provides the endocrinologist with essential updates on treatment of type 1 diabetes, with an eye toward future trends and developments.? The Guest Editors brought together a remarkable group of notable authors, such as Paul Robertson, President of the National Diabetes Association.? Topics covered include epidemiology; economics; contemporary management; inpatient management; update on insulin pumps and continuous glucose monitoring systems; update on studies aimed at interdicting and preventing type 1 diabetes; advances in the prediction, natural history, and mechanisms leading to type 1 diabetes; complications; hypoglycemia in type 1 diabetes; new lessons from animal models; the role of the gut in the genesis of type 1 diabetes and other autoimmune diseases; and an update on transplantation for reversing type 1 diabetes.

Diabetic Neurology offers a unique focus on the broad neurological complications of diabetes, bridging the clinical divide between diabetology and neurology with a practitioner-friendly guide for the recognition, investigation and management of diabetic patients with neurological disease.

This book provides a comprehensive, practical review of the problems encountered at the interface of diabetes and neurology. The point form format facilitates a thorough summary of the diabetological and neurological approach to patients and their related disease states.

The authors of this book bring together their expertise in these shared fields to address the problems neurologists may encounter in diabetic patients and the important neurological issues to consider in diabetes clinics. The emphasis is on adult patients and some topics are deliberately covered in more than one section, depending on the context of the discussion.

The book s three sections provide:

* An overview of diabetes care directed towards neurologists and of neurological basics directed towards diabetologists
* A summary of various neurological presentations, both common and serious, which both specialties must be cognizant of
* A discussion of rare conditions, their neurological and diabetic complications

This book is a comprehensive and useful reference for diabetologists, endocrinologists, internists and neurologists.

People with diabetes are two to four times more likely to develop cardiovascular disease.? Insulin resistance, which leads to diabetes in 1 in 4 people who have it, affects 60 million Americans and is also a cardiovascular disease risk factor.? It is important for cardiologists to understand the reasons why diabetes and insulin resistance cause increased cardiovascular risk so they can help their patients control these risk factors.

Emphasizing a team approach that includes the practicing podiatrist, endocrinologist, diabetologist, vascular surgeon, orthopedist, and infectious disease specialist, The High Risk Diabetic Foot provides a thorough and detailed resource on the management of complex diabetic foot problems. This comprehensive text is an essential tool that will enable physicians to reduce infections and amputations through careful examination, diagnosis, treatment, and prevention.

Key features in The High Risk Diabetic Foot include:

• A full section devoted to the prevention of amputation
• High-quality images for accurate diagnosis
• Chapters organized by epidemiology, classification and staging, diagnosis, special studies, and medical and surgical management
• Summary tables and flow charts for quick reference
• A discussion of the co-morbidities associated with diabetic foot pathology, including sensory neuropathy, painful neuropathy, peripheral vascular disease, food wounds, and more
• Identification of the level of medical evidence associated with treatment recommendations

This book addresses diabetic retinopathy, an eye disease that remains one of the main causes of vision loss if not diagnosed and managed properly. It aims to cover the entire spectrum of the disease by describing its clinical identification and characterization, pathophysiology, epidemiology, and medical and surgical management. Diabetic Retinopathy also offers a complete overview of the present understanding of diabetic retinopathy, covering current practice but also including original contributions that offer novel perspectives for looking at and addressing this disease.

The author has dedicated his lifetime to the study of diabetic retinal disease and has organized this book around his personal experience but at the same time giving the necessary information for updated management of diabetic retinopathy. Diabetic Retinopathy will be especially useful for postgraduate students in diabetology, retina specialists and researchers.

While nutrition is central to the management of diabetes, there is no one "diabetic diet". Nutritional prescriptions depend on the type of diabetes, food preferences, lifestyle, treatment regimen, comorbidities, state of health, and the route of caloric administration. Nutritional Strategies for the Diabetic/Prediabetic Patient is a comprehensive reference aimed at advancing physicians' knowledge of nutrition in relation to diabetes, allowing them to provide evidence-based recommendations for their diabetic patients. It also provides dietitians and diabetic educators with an in-depth understanding of the pathophysiology and medical treatment of diabetes. Written by scientists, clinicians, registered dietitians, and certified diabetes educators, this book reviews the molecular mechanisms of disease and drug therapy. It also provides recommendations for management with the level of evidence indicated where appropriate. In areas where little research data is available, the editors present recommendations based on extensive clinical experience. The book places particular focus on the synchronization of nutrient intake with medications, and provides unique clinical management tools, along with details of their ability to be replicated for patient use. To facilitate accessibility, it features evidence-based technical reviews of clinical literature and includes numerous tables and figures, with color photos of wound healing stages. Addressing all aspects of nutrition in adult diabetic and prediabetic patients, Nutritional Strategies for the Diabetic/Prediabetic Patient is an important referencefor those concerned with the dietary management of this disease.

From the pioneer of diabetes reversal and creator of the 'Newcastle Diet'

For centuries type 2 diabetes was regarded as an incurable, lifelong condition. Even worse, it seemed to be inevitably progressive – but no longer.

Professor Roy Taylor is one of the world’s leading experts on type 2, the man who in 2006 finally found the missing piece of the jigsaw explaining that it was actually a reversible condition. With his team of researchers at Newcastle University, he launched a series of studies leading to a remarkable, multi-million-pound trial, which in 2019 confirmed that simple advice about diet could bring about lasting remission.

In this book, Taylor brings all the knowledge and experience of four decades of treating people with diabetes. He explains exactly what is happening in the body as type 2 diabetes develops and shows how you can live a full and healthy life beyond it.

** Includes the 3-step Newcastle weight loss programme, as well as delicious tried-and-tested recipes from participants of the diabetes reversal trials **

Recent research in diabetes has proven Type 1 diabetes is no longer only a juvenile disease. It has been projected adult Type 1 diabetes will increase 40% from 1997-2010, and as our understanding of the pathogenesis of Type 1 and Type 2 diabetes grows - it is apparent that some cases previously classified as Type 2 are actually adult onset Type 1 diabetes. This volume is the first to focus exclusively on Type 1 diabetes in adults, seeks to clarify the complexities by explaining latest concepts in the pathophysiology and management of the disease, and to assist clinicians in the optimal utilization of cutting edge technology, therapeutics, and management strategies available to them.

The incidence and prevalence of type 2 diabetes mellitus have increased dramatically in modernized and developing nations over the past few decades. Thoroughly revised and expanded, this Second Edition responds to the epidemic and supplies a current overview and guide to the management of diabetes in the modern healthcare environment. This Second Edition offers a current perspective on diabetes demographics, epidemiology, pathophysiology, disease monitoring, and approaches to glucose control, and supplies new chapters by world-renowned experts on non-pharmacological management options, complications of the skin and urogenital function, related macrovascular conditions, coronary heart disease, stroke, and peripheral vascular disease, and rare forms of diabetes, PCOS, and NASH.

Whether you have been living with type 1 diabetes for some time, or you have just discovered that your child is diabetic, there's a lot you need to know about the new developments in treating, controlling, and living with this disease. Type 1 Diabetes For Dummies, explains everything you need to know and do to make living with type 1 diabetes easier and healthier. This reassuring, plain-English guide helps you understand and mange the disease with tips on working with your doctor, administering insulin, developing a diet an exercise plan, and coping with illness and travel. You'll find out about the latest technologies of blood glucose monitoring and insulin delivery, and get a handle on everything you need to do to keep yourself or your child healthy, active, and feeling good. Discover how to:* Overcome short-term complications* Eat a diabetes-friendly diet* Use exercise to help control type 1 diabetes* Handle school, work, and other activities* Help your child maintain a high quality of life* Prevent long-term complications* Be healthier than your friends who don't have diabetes* Deal with the emotional and psychological effects of the disease* Choose an insulin pump for yourself or your child* Calculate insulin dosages Anyone can live a long, healthy, and productive life with type 1 diabetes. Small Type 1 Diabetes For Dummies delivers every drop of information you need to make sure that you or your child can do just that.