Approximately 29 million Americans are diagnosed with Type 2 diabetes annually. Of that number, only about 36 percent (10.44 million diabetes sufferers) achieve satisfactory medical outcomes and would need additional help-rarely available-to reliably control their glucose levels. Contrary to popular belief, although anti-diabetic medications can lower sugar levels, nevertheless they have a poor performance track record because inflammation in the blood vessels persists. This book details recent scientific findings that cardiovascular, kidney, vision, peripheral nervous system, and other body damage caused by chronic high levels of blood sugar (hyperglycemia) in Type 2 diabetes is actually due to excessive generation of unopposed free radicals and reactive oxygen species (ROS). These, in turn, cause chronic systemic inflammation and dysfunction of the endothelial lining of the arterial blood vessels, jeopardizing the formation of the protective molecule nitric oxide (NO), thus severely impairing the blood supply to every organ and tissue in the body. This book also catalogues the evidence that chronic hyperglycemia causes profound and often irreversible damage-even long before Type 2 diabetes has been diagnosed. In addition, because conventional prescription treatments are, unfortunately, often inadequate, the book details evidence-based complementary means of blood sugar control.

Approximately 29 million Americans are diagnosed with Type 2 diabetes annually. Of that number, only about 36 percent (10.44 million diabetes sufferers) achieve satisfactory medical outcomes and would need additional help-rarely available-to reliably control their glucose levels. Contrary to popular belief, although anti-diabetic medications can lower sugar levels, nevertheless they have a poor performance track record because inflammation in the blood vessels persists. This book details recent scientific findings that cardiovascular, kidney, vision, peripheral nervous system, and other body damage caused by chronic high levels of blood sugar (hyperglycemia) in Type 2 diabetes is actually due to excessive generation of unopposed free radicals and reactive oxygen species (ROS). These, in turn, cause chronic systemic inflammation and dysfunction of the endothelial lining of the arterial blood vessels, jeopardizing the formation of the protective molecule nitric oxide (NO), thus severely impairing the blood supply to every organ and tissue in the body. This book also catalogues the evidence that chronic hyperglycemia causes profound and often irreversible damage-even long before Type 2 diabetes has been diagnosed. In addition, because conventional prescription treatments are, unfortunately, often inadequate, the book details evidence-based complementary means of blood sugar control.

The clinical management of patients with diabetes is rapidly evolving. Evidence-based Management of Diabetes provides a succinct summary of a range of topics, including areas where there is already well developed evidence for a particular treatment, but also those areas where the evidence is perhaps doubtful or there is some associated controversy or ambiguity. Where possible throughout the book treatment recommendations are given based on the available evidence and practice guidelines. The book also highlights the gaps in evidence where further research is needed. In the practice of diabetes care, there are many issues influencing practitoners currently. This book addresses many of the most pertinent issues concerning delivery of diabetes care such as: Is diabetes preventable in high-risk individuals? Once diabetes has developed what are the goals of treatment and how aggressive should treatment be whilst avoiding adverse effects? What is the role of treating glycaemia in reducing macrovascular disease? Who to screen, how to screen and who to treat for coronary artery disease? Who and how to treat hyperglycaemia in acute coronary syndromes? Has there been any progress in the management of gestational diabetes? Is there an evidence base for the treatment of Type 2 diabetes with oral hypoglycaemic agents? The authors are internationally renowned experts in the field of diabetes care who successfully and succinctly present state-of-the-art reviews based on the medical evidence designed to help the clinician be as best informed as possible in the care of patients with diabetes.

In the past few decades a revolution in our approach to treating type 2 diabetes has occurred following the recognition that the condition is caused by multiple defects. A range of new treatments are now available, with many more forthcoming, utilising differing mechanisms of action that allow targeted and more effective therapy of this multifactorial disease than ever before. The increasing requirement in the UK to move much of diabetes practice into the community requires much more detailed knowledge of the condition by GPs and practice nurses. In this bespoke book, the authors aim to show how new mechanisms of glucose control and advances in treatments arising from this can tailor treatment to the individual in primary care. This book incorporates the recently published ADA/EASD guidelines and the 2015 update from the National Institute for Health and Clinical Excellence (NICE). Essential reading for the multi-professional diabetes care team, this book should also be of interest to hospital specialists in training.

Diabetes is a prevalent disorder throughout the world; it has become a universal topic for conversation superseding topics like heart disease or cancer. Self-care and taking responsibility for the illness are integrally important in diabetes so that the patient stays healthy and complications do not develop. Self-care consists of the following: a prescribed diabetes diet, indulging in daily physical activities and taking prescribed doses of insulin. Self-care is promoted through repeated education by doctors and allied health professionals who are knowledgeable in diabetes, pathophysiology and clinical diabetes care. The Handbook of Diabetes for General Practitioners is written for doctors to apprise the fundamentals of diabetes including its recognition as an entity, the discovery of insulin for the treatment of diabetes, pathophysiology of diabetes, and the development and progression of diabetic complications and how to minimize or prevent the complications. Also, several chapters are written to focus on the common flaws in the diagnosis and improper treatment of diabetes. Incorrect diagnosis and treatment of drug-induced hyperglycemia leads to the development of overt diabetes with a range of complications. Diabetic complications are serious, disabling and economically disastrous for healthcare providers. By reading this book, doctors and allied health professionals will be better prepared to deal with the adversities of diabetes to ultimately help their patients live a complication-free life.

'Excellent book - written for patients but also great for clinicians' - Amazon 5-star reader review '[Busting the Diabetes Myth] should be compulsory reading for anyone recently diagnosed.' - Amazon 5-star reader review 'Full of valuable information about the condition and how to beat it' - Amazon 5-star reader review Busting the Diabetes Myth provides an effective and evidence-based approach to guide people with type 2 diabetes and prediabetes towards a healthier future. Focusing on the lifestyle changes that help reverse the diabetes disease process, the book will be an invaluable source of hope and inspiration for the millions of people with type 2 diabetes and prediabetes around the world. Drawing upon Dr Cavan's extensive research into diabetes management and his professional experience, Busting the Diabetes Myth reveals the latest scientific evidence behind his innovative approach in helping people reverse their diabetes, providing specific advice for people with prediabetes as well as those with type 2 diabetes. Explaining in easy-to-understand terms how today's lifestyles are driving millions of people into prediabetes and then on to developing type 2 diabetes, the author then describes the changes we can make to halt the process in its tracks, and help people turn around their health to look forward to a future free from diabetes. Advocating a diet based on healthy fresh foods that avoids sugars, refined carbohydrates and other highly processed foods, and with simple suggestions for how to incorporate physical activity into the daily routine, this accessible guide shows us sustainable and achievable ways of adjusting our lifestyles to reverse prediabetes and type 2 diabetes, authenticated with first-hand testimonies from people who in following Dr Cavan's evidence-based approach have already done just that.

Essential reading for all diabetes sufferers and those at risk, this guide explains how the disease is completely reversible through nutrition and supplements, even in the late stage Offering a complete action plan for sufferers of type 1 diabetes, type 2 diabetes, and the forerunner of type 2 diabetes, metabolic syndrome, this guide also provides motivating case histories and evidence of support by the latest scientific findings. Nutrition expert Patrick Holford discusses the causes of the current diabetes problem, explains the 10 secrets for preventing and reversing diabetes and metabolic syndrome, and provides an antidiabetes diet, a daily supplement program, and advice on how to undo the damage caused by the disease and diabetes drugs. This easy-to-follow program will help readers regulate out-of-control blood sugar levels safely and effectively, with no dangerous side effects.

Diabetes occurs at such an alarming rate that it can be described as a global epidemic. Following its predecessor, Nutrition and Diabetes: Pathophysiology and Management, Second Edition, is a comprehensive resource that describes various factors that drive the accumulation of excess body weight and fat resulting in obesity. The book discusses the metabolic aberrations found in obesity and how they lead to the association of obesity with diabetes. This new edition highlights the role played by diet and the interrelationships in the metabolism of key nutrients in the pathogenesis of obesity and diabetes which provides the scientific basis for treatment and management approaches. Features Highlights the role of nutrition in the pathogenesis of obesity and diabetes Organized logically into two easy-to-use sections - Pathophysiology and Management of Obesity and Pathophysiology and Treatment of Diabetes Features emerging therapeutic approaches for management of obesity and diabetes Discusses experience in the management of obesity and diabetes in developing countries Presents challenges in insulin therapy and provides guidelines to overcome them The first section of the book retains key topics from the previous edition and contains new chapters including genetic determinants of nutrient processing; fat distribution and diabetes mellitus; combined effect of diet and physical activity in the management of obesity; pharmacologic treatment of obesity; and the role of gut microbiota in the pathogenesis and treatment of obesity. The second section features updated versions of most of the other chapters in the first edition comprising a modified chapter on oxidative stress and the effects of dietary supplements on glycemic control in Type 2 diabetes. In addition, new chapters are added in this section and include the contribution of iron and transition metal micronutrients to diabetes; role of microbiota in the pathogenesis and treatment of diabetes; primary prevention of Type 2 diabetes; and the pathophysiology and management of Type 1 diabetes.

This is a book dedicated to the presentation of the latest research on selected issues associated with type 1 diabetes. The authors are well-known professors of Polish medical universities who published numerous scientific papers. Type 1 diabetes is the predominant form of diabetes in young people. It is an autoimmune disease which is particularly aggressive in small children. It is also a pandemic illness characterised by autoimmune, genetic and metabolic abnormalities. It concerns mainly children and young people, and therefore is a condition the patient will have to struggle with for many years hence. This is why it is extremely important to maintain maximum metabolic compensation to delay the occurrence of chronic complications which are an issue not only for the patient, but also for the society as a whole, as they involve a considerable financial burden. At present, we can observe the development of great advances in the treatment of this form of diabetes. Modern insulin preparations have been introduced as well as improved methods of glucose monitoring and insulin delivery. New ways to delay the autoimmune processes are being studied and implemented. It is becoming more and more realistic to create the "artificial pancreas", which should greatly facilitate the achievement of normal metabolic control. In the long term, a possibility may exist to completely cure diabetes. A wide dissemination of knowledge concerning the latest research on type 1 diabetes is extremely important among patients and, above all, among medical practitioners. This book is to serve as an approximation of the latest knowledge for physicians who take care of patients with diabetes on a daily basis.

The future of persons with Type 1 Diabetes Mellitus is continuing to "look brighter" with the advent of biomedical technology. Nevertheless, the acute consequences of this disease remains a significant threat. Diabetic ketoacidosis [DKA] remains the most serious challenge for primary care physicians and subspecialists caring for children and young persons with Diabetes Mellitus. Its prevention is possible only among those already diagnosed. Awareness of the etiology and clinical presenting signs among children of all ages is requisite for primary care and emergency department staff [Chapter 1]. While more likely to occur among those with Type 1 diabetes, a significant proportion of children with Type 2 diabetes are also at risk [Chapter 3]. Once diagnosed, the physician team must understand not only what biochemical imbalances must be corrected, but also what life-threatening complications must be avoided [Chapter 1]. The path through that "maze" is not yet fully interpreted; many choices remain as options, but each must be carefully evaluated. Diagnosis among the very young is a challenge because of they lack self-awareness and clarity of signs and symptoms [Chapter 2]. Education of the primary care staff is critical and able to alter the incidence of DKA at the time of diagnosis. Institutions that treat children and adolescents with DKA need an informed Emergency Department as well as Pediatric Intensive Care Facilities. Access to appropriate consultations, such as pediatric endocrinology, cardiology, neurology and neurosurgery are crucial. The initiation of care is critical, and occurs invariably in the Emergency Department [Chapter 4]. Meticulous documentation of fluid composition and volume, insulin administration, vital signs and neurological state of well-being is essential. These will facilitate the transition to the appropriate in-patient service, whose task is to understand the biological impact of fluid rehydration and fluid flux, as well as hypocapnea, hyperglycemia and cranial perfusion [Chapter 5]. The current standards of care all but prevent most of the varied biochemical complications of "appropriate" care for persons with DKA. However, awareness of these possibilities is crucial [Chapter 6]. Yet, one complication remains unexplained and too often unpredicted, and it is devastating to the pediatric patient: cerebral edema. This complication, its prevention and treatment are discussed [Chapter 6]. Type 2 diabetes mellitus is continuing to increase in incidence and prevalence among all ages. Once thought to be "non-ketosis prone" diabetes, now persons undiagnosed or previously diagnosed do obtain DKA. They, however, have other unique medical requirements that must be applied to their treatment [Chapter 3]. Hyperglycemic hyperosmolar state is a complication no longer limited to adults with diabetes or children with Type 2 diabetes mellitus. While the incidence is fortunately lower than that of DKA, its outcome is potentially direr. Appreciation of the unique treatment requirements and guidelines are discussed [Chapter 7]. This monograph provides a comprehensive compendium to those caring for children of all ages with diabetic ketoacidosis, its related disorders and associated conditions.

Covering cases from Addison's disease to osteoporosis and diabetic foot ulcer, and an introductory section explaining the molecular and physiological aspects of endocrinology, "Endocrinology and Diabetes: Clinical Cases Uncovered" has it all. Reflecting the varied nature of the specialty, the cases cover various endocrine conditions and address the clinical presentation, diagnostic workup and potential complications, while the self-assessment section, comprising 30 MCQ, 10 SAQs and 10 EMQs, will help medical students, junior doctors, and nurses practise clinical reasoning and prepare for life on the wards.

This important reference, edited by Ronald Ross Watson and Betsy Dokken, collects the research needed to make the distinct connection between pre-diabetes, diabetes, and cardiovascular disease. Glucose Intake and Utilization in Pre-Diabetes and Diabetes: Implications for Cardiovascular Disease explains the mechanisms of progression from pre-diabetes to diabetes to cardiovascular disease. Since pre-diabetes and diabetes are important cardiovascular disease risk factors, and impaired glucose metabolism among cardiac patients is extremely prevalent, the importance of reviewing pre-diabetes and its involvement in CVD complications is vital as one applies food and glycemic control to slow progress to diabetes and heart disease. The book further focuses on glucose intake and utilization in diabetes, including coverage of diabetes in the development and pathology of cardiovascular disease, risks and epidemiology of cardiovascular problems promoted by diabetes, macrovascular effects and their safety in therapy of diabetics, beta cell biology and therapy of diabetes, and nutrition to modulate diabetes.

"The Handbook of Nutrition, Diet and the Eye" is the first book to thoroughly address common features and etiological factors in how dietary and nutritional factors affect the eye.

The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss can be devastating. One of the biggest contributors to complete vision loss in the western hemisphere is diabetes, precipitated by metabolic syndrome. In some developing countries, micronutrient deficiencies are major contributory factors to impaired vision. However, there are a range of ocular defects that have either their origin in nutritional deficiencies or excess or have been shown to respond favorably to nutritional components. The eye from the cornea to the retina may be affected by nutritional components. Effects may be physiological or molecular.

This book represents essential reading for nutritionists, dietitians, optometrists, ophthalmologists, opticians, endocrinologists, and other clinicians and researchers interested in eye health and vision in general.
Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of nutrition, ocular health, and disease issuesProvides a common language for nutritionists, nutrition researchers, optometrists, and ophthalmologists to discuss how dietary and nutritional factors, and related diseases and syndromes affect the eyePreclinical, clinical, and population studies will help nutritionists, dieticians, and clinicians map out key areas for research and further clinical recommendations

Approaching diabetes from a multidimensional perspective, Evan Soroka links the practices and philosophy of yoga with science and lived experience. In this book, she addresses the major challenges of type 1 and type 2 diabetes, providing descriptive practices including spinal movements, breathing techniques and meditation. By giving yoga therapists and yoga teachers the tools to encourage a positive mindset in the person with diabetes and therefore putting them in charge of their own health, this manual helps to identify what might be out of balance and how to restore it.

The Essential Charcot Neuroarthropathy: Biomechanics, Pathophysiology, and MRI Findings provides a comprehensive analysis of Charcot neuroarthropathy (or Charcot Foot) in diabetic patients. All aspects are covered, including epidemiology, biomechanics, pathophysiology, socioeconomic impacts, radiological findings, and differential diagnosis, with an emphasis on MRI. Chapters address the challenges of pre-and-post surgical management of Charcot neuroarthropathy and the role of unconventional imaging modalities in diagnosis. The book presents an analysis of the normal biomechanics of the ankle and foot, the biomechanical derangements of the ankle-foot unit (including abnormal gait) caused by diabetes Type II, and more. Finally, there is also a reference of the pathophysiology of diabetes-induced peripheral neuropathy and its direct link with the development of Charcot neuroarthropathy foot. Diabetes-induced Charcot foot is frequently misunderstood, misinterpreted and misdiagnosed which can lead to confusion and detrimental management with reported high morbidity.

Is diabetes curable? What is the difference between sugar and glucose? Is urine sugar testing to monitor control of diabetes better or is blood glucose testing better? Do most diabetics die from diabetes or do they die from something else? Can I use herbs to control my diabetes? There are many questions that a diabetic may have. We have the answers. Many diabetics waste a lot of money and time trying to follow some myths about diabetes and its treatment. This DVD dispels 25 of such myths and thus helps a diabetic better manage his/her diabetes and minimise chances of suffering complications and disability from diabetes. Approximate running time: 60 minutes.

Traveling with Sugar reframes the rising diabetes epidemic as part of a five-hundred-year-old global history of sweetness and power. Amid eerie injuries, changing bodies, amputated limbs, and untimely deaths, many people across the Caribbean and Central America simply call the affliction "sugar"-or, as some say in Belize, "traveling with sugar." A decade in the making, this book unfolds as a series of cronicas-a word meaning both slow-moving story and slow-moving disease. It profiles the careful work of those "still fighting it" as they grapple with unequal material infrastructures and unsettling dilemmas. Facing a new incarnation of blood sugar, these individuals speak back to science and policy misrecognitions that have prematurely cast their lost limbs and deaths as normal. Their families' arts of maintenance and repair illuminate ongoing struggles to survive and remake larger systems of food, land, technology, and medicine.

The heartwarming true story of how one man's life was saved by adopting an overweight, middle-aged shelter dog named Peety. Eric O'Grey was 150 pounds overweight, depressed, and sick. After a lifetime of failed diet attempts, the onset of serious diabetes due to his weight prompted Eric to see a new doctor, who surprisingly prescribed adopting a shelter dog. And that's when Eric met Peety: a middle-aged and forgotten shelter dog who, like Eric, had seen better days. The two adopted each other and began an incredible journey together. Over the next year, just by going on walks, playing together and eating plant-based food, Eric lost 150 pounds and Peety lost 25. The bond of unconditional love he and Peety formed forever changed their lives. As a result, Eric reversed his type 2 diabetes, got off all medication, became happy and healthy for the first time in his life, and even reconnected with and married his high school sweetheart. WALKING WITH PEETY is perfect for anyone who is ready to make a change in their life and for everyone who knows the joy, love and hope that dogs can bring to human lives. This is more than a tale of mutual rescue; this is an epic story of friendship and strength.

This title includes 5 DVDs. DVD 1: "Essentials Of Diabetes" - What is diabetes? Why diabetes occurs? Who gets it? How insulin, cell and glucose control blood glucose (sugar) levels? Types of diabetes; And symptoms of diabetes due to high blood glucose levels and low cell glucose. DVD 2: "Blood Glucose" - What is blood glucose? Blood glucose or blood sugar - Which is the right term? Where does glucose come from in body? How are normal blood glucose levels maintained in a non-diabetic person? What happens in diabetes? Symptoms of high blood glucose; And how common treatments for diabetes work? DVD 3: "A1C and diabetic control" - What is A1C? Where does A1C in our body come from? What is normal A1C level? What complications can occur in a diabetic if A1C levels are high? A1C and blood glucose; How are they related? How to bring high A1c levels back to normal? And what can be associated dangers when lowering the levels? DVD 4: Low Blood Sugar (Glucose)" Causes, dangers and symptoms of low blood glucose levels; Why can low blood glucose level be a threat to a diabetic's life? How to correct the low blood glucose in the right ways; and, includes important points to consider preventing serious permanent damage to your body due to low blood glucose (sugar). DVD 5: "Foot Care In Diabetes" - how to prevent foot loss in diabetes; normal foot care in diabetes; warning signs of impending foot damage; And what to do to save your foot if one of these warning signs appear in your toes, foot or leg?

Narrative Based Health Care: Sharing Stories recounts the experiences of a group of patients undergoing treatment for diabetes, may of whom are poor, socially isolated, and unable to communicate their fears and anxieties to health professionals.

The book is a practical and highly accessible supporting tool for GPs, nurses and health professionals interest in professionals development and improving services for patients. The innovative approach employed by Narrative Based Health Care is not limited to the understanding of diabetes and will therefore be of interest to all health professionals interested in addressing the clinical and service needs for any complex health problem.

The book covers a wide range of experiences, including:
Learning about diabetes
The person with newly diagnosed diabetes
Diabetes in the family
Check-ups and visits to the doctor
Medication
Supporting positive lifestyle choices
Loneliness and lack of support
Communicating across cultures
Educating and supporting other health professionals
Diabetes and women's health

Diabetes Without Needles: Non-invasive Diagnostics and Health Management provides a comprehensive and objective compilation of the most promising noninvasive methods for glucose monitoring, including an in-depth analysis of their advantages and disadvantages in terms of biochemical processes. The latest advances in the field are discussed, including methods such as optical measurements, electrochemical measurements, exhaled breath analysis, direct measurements of glucose in the blood using noninvasive techniques, and the indirect analysis of biomarkers that are related to the glycemia. The book's author also presents recommendations for future research directions in this field. This book is a valuable resource for researchers in the areas of diabetes, noninvasive methods and diagnostics development.

"Advances in Immunology, " a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology.
This thematic volume focuses on the immunopathogenesis of type 1 diabetes mellitus. Edited and authored by the foremost scientists in this field, it provides up-to-date information and directions for future research.

Deciphers amylin's physiology and reveals previously unrecognized mechanisms fundamental to control body weight and fuel homeostasis. Also discusses therapeutic utility of amylin as the first new medicine to treat diabetes since insulin.
*Provides a current comprehensive treatment of amylin the hormone
*Identifies the majority of amylin's physiologic functions

This is both an important and an unusual book. It is important because not only is there an increasing number of people developing Type 2 Diabetes but also there is a large hidden population undiagnosed with the disease which increases the risk of developing other chronic diseases. It is unusual in that, unlike many books about medical conditions and dietary changes, this book is refreshingly relaxed, non-judgemental, easy to read, and above all concise. The recommendations in the book are a combination of not just many years of professional academic research but also of personal experiences. The latter involved reversing and reducing both pre- and existing Type 2 Diabetes diagnosed at relatively young ages by both the author and her sister respectively. Marie does not insist on a long list of required lifestyle changes but rather invites her audience to pick just a few of those she recommends. Providing they become constant, relatively small changes in diet and short periods of exercise can be sufficient to reverse Type 2 Diabetes. Fundamentally, these involve consuming low-carbohydrate foods and reducing stress by doing simple exercises. Clearly and concisely, the author lists ingredients and recipes designed to make food ‘more efficient’. This, the author insists, is a short ‘Guidebook….to a heathier and happier life’.

Gastrointestinal function represents an important, and hitherto inappropriately neglected, aspect of diabetes management. Disordered gastrointestinal motor and sensory function occurs frequently in both type 1 and type 2 diabetes and may be associated with gastrointestinal symptoms that adversely affect quality of life. During the last two decades there has been a rapid expansion in knowledge in this area. It is now recognised that upper gastrointestinal motility is pivotal to the regulation of postprandial blood glucose concentrations in both health and patients with diabetes. This book is the first of its kind and was stimulated by the need to consolidate these recent advances, which dictate that a knowledge of gastroenterology as it relates to diabetes is now required of the clinician/diabetologist.

• Features an organ-specific overview of the epidemiology and pathophysiology of disordered gastrointestinal (including hepatobiliary and pancreatic) function in diabetes mellitus

• Contains guidelines for the clinician, diabetologist and gastroenterologist for both diagnosis and management.

• Includes a comprehensive description of the relation between gastrointestinal function, gastrointestinal hormones, autonomic nerve function and glycaemic control in animal models.

• Covers the development of new treatment options, particularly those targeted at the reduction of postprandial hyperglycaemia, to optimise glycaemic control.

Target audience: gastroenterologists, diabetologists, specialist nurses and clinical researchers.