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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes

Polycystic Ovary Syndrome - Current Controversies, from the Ovary to the Pancreas (Paperback, Softcover reprint of hardcover... Polycystic Ovary Syndrome - Current Controversies, from the Ovary to the Pancreas (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Andrea Dunaif, R.Jeffrey Chang, Stephen Franks, Richard S. Legro
R3,169 Discovery Miles 31 690 Ships in 10 - 15 working days

This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

RNA Binding Proteins - New Concepts in Gene Regulation (Paperback, Softcover reprint of hardcover 1st ed. 2002): Kathryn... RNA Binding Proteins - New Concepts in Gene Regulation (Paperback, Softcover reprint of hardcover 1st ed. 2002)
Kathryn Sandberg, Susan E. Mulroney
R5,587 Discovery Miles 55 870 Ships in 10 - 15 working days

RNA binding proteins are an exciting area of research in gene regulation. A multitude of RNA-protein interactions are used to regulate gene expression including pre-mRNA splicing, polyadenylation, editing, transport, cytoplasmic targeting, translation and mRNA turnover. In addition to these post-transcriptional processes, RNA-protein interactions play a key role in transcription as illustrated by the life cycle of retroviruses. Unlike DNA, the structure of RNA is highly variable and conformationally flexible, thus creating a number of unique binding sites and the potential for complex regulation by RNA binding proteins. Although there is a wide range of topics included in this volume, general themes have been repeated, highlighting the overall integrative nature of RNA binding proteins. The chapters have been separated into three different sections: Translational Control; mRNA Metabolism; and Hormonal and Homeostatic Regulation. The chapters of this volume were written with the seasoned investigator and student in mind. Summaries of key concepts are reviewed within each chapter as well as guiding questions that can be used to stimulate class discussions. The Editors of this volume hope that this compendium educates, enthralls, and stimulates the readers to look to the future possibilities in this rapidly evolving field.

Diabetes Mellitus (Paperback, Softcover reprint of hardcover 1st ed. 2003): Sabire OEzcan Diabetes Mellitus (Paperback, Softcover reprint of hardcover 1st ed. 2003)
Sabire OEzcan
R3,582 Discovery Miles 35 820 Ships in 10 - 15 working days

Diabetes mellitus is the collective name for a group of diseases associated with hyperglycemia (high levels of blood glucose) caused by defects in insulin p- duction, insulin action, or both. About 6. 2% of the US population (17 million people) have diabetes mellitus. It is the leading cause of kidney failure, bli- ness, and amputations. It is also a major risk factor for heart diseases, stroke, and birth defects. Diabetes Mellitus: Methods and Protocols provides a state-of-the-art account of the experimental methodology for studying the molecular defects leading to diabetes mellitus, both at the molecular and biochemical levels. The chapters cover a wide range of topics written by experts in their respective fields and are organized in two sections: Insulin Production and Insulin Action. The detailed experimental protocols presented, including the notes of interest, provide a very useful tool for basic researchers and clinicians for investigating and treating this disease. Each chapter starts with an introduction to a specific technique and explains its application in the field of diabetes research. Following the list of materials, a detailed description of the technique is presented in the methods section in a way that enables the successful execution of the protocol. The "Notes" section at the end discusses the pitfalls of the technique and alternative approaches. I am grateful to the numerous scientists who have contributed to this volume by writing both highly detailed and understandable chapters.

The Metabolic Syndrome and Obesity (Paperback, Softcover reprint of hardcover 1st ed. 2007): George A Bray The Metabolic Syndrome and Obesity (Paperback, Softcover reprint of hardcover 1st ed. 2007)
George A Bray
R4,378 Discovery Miles 43 780 Ships in 10 - 15 working days

This book presents an up-to-date survey of the current scientific understanding of obesity and the metabolic syndrome, as well as an overview of the most significant changes to the field over the past 30 years. The book defines obesity and realistically assesses its prevalence. It further examines and evaluates the success of traditional cognitive behavioral treatment. This volume is a thorough reference for obesity and the metabolic syndrome.

The Metabolic Syndrome: - Epidemiology, Clinical Treatment, and Underlying Mechanisms (Paperback, Softcover reprint of... The Metabolic Syndrome: - Epidemiology, Clinical Treatment, and Underlying Mechanisms (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Barbara C. Hansen, George A Bray
R6,399 Discovery Miles 63 990 Ships in 10 - 15 working days

This book covers the most important clinical and bench science aspects of metabolic syndrome. It will be of value to all of those seeking a comprehensive update on the metabolic syndrome. Furthermore, it will provide a broad basis for advancing research in the multiple intersecting disciplines encompassed by the metabolic syndrome.

Treatment of the Obese Patient (Paperback, Softcover reprint of hardcover 1st ed. 2007): Robert F. Kushner, Daniel H. Bessesen Treatment of the Obese Patient (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Robert F. Kushner, Daniel H. Bessesen
R6,369 Discovery Miles 63 690 Ships in 10 - 15 working days

The aim of this book is to inform clinicians of recent advances in obesity research and provide a review of current treatment issues and strategies. Part 1 covers new discoveries in the physiological control of body weight, as well as the pathophysiology of obesity. Part 2 covers a range of issues that are central to the clinical management of obese patients. This illustrated volume will stimulate and engage clinicians.

Educating Your Patient with Diabetes (Paperback, Softcover reprint of hardcover 1st ed. 2009): Katie Weinger, Catherine A.... Educating Your Patient with Diabetes (Paperback, Softcover reprint of hardcover 1st ed. 2009)
Katie Weinger, Catherine A. Carver
R3,601 Discovery Miles 36 010 Ships in 10 - 15 working days

Diabetes affects an estimated 20 million people in the United States, with many people remaining unaware that they suffer from the disease. While the number of diabetics continues to rise, the number of caregivers who specialize in diabetes treatment does not. In Educating Your Patient with Diabetes, Katie Weinger and Catherine Carver assemble commentary from a panel of leading diabetes practitioners and researchers and put together a highly readable guide to supplying patients with diabetes with the information and ability to successfully cope with their disease. The authors and editors provide substantive data on successful models of diabetes education and the process of educating diabetes sufferers. Additional chapters discuss diabetes in pregnancy, the challenge of weight and diabetes management in clinical practice, and diabetes education in geriatric populations. Timely and accessible, Educating Your Patient with Diabetes is a must have for all diabetes educators, physician assistants, nurses, and endocrinologists who endeavor to support their patients' diabetes self-care efforts and help them maximize the opportunities for patient learning.

When Puberty is Precocious - Scientific and Clinical Aspects (Paperback, Softcover reprint of hardcover 1st ed. 2007): Ora H.... When Puberty is Precocious - Scientific and Clinical Aspects (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Ora H. Pescovitz, Emily C. Walvoord
R4,437 Discovery Miles 44 370 Ships in 10 - 15 working days

This book focuses on precocious puberty, providing a unique continuum of expertise looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. In particular, the book is intended for endocrinologists and internists.

Controversies in Treating Diabetes - Clinical and Research Aspects (Paperback, Softcover reprint of hardcover 1st ed. 2008):... Controversies in Treating Diabetes - Clinical and Research Aspects (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Derek Leroith, Aaron I. Vinik
R3,139 Discovery Miles 31 390 Ships in 10 - 15 working days

This book addresses diabetes controversies, specifically in the management of etiology and the disease itself. Chapters also examine the complications associated with diabetes. The volume covers commonly accepted forms of therapies and complications, as well as new and emerging advances and therapies and inadequacies in several standard treatments. Comprehensive and timely, this book is an essential reference for those treating and researching diabetes.

Neuropsychological and Behavioral Aspects of Diabetes (Paperback, Softcover reprint of the original 1st ed. 1990): Clarissa S.... Neuropsychological and Behavioral Aspects of Diabetes (Paperback, Softcover reprint of the original 1st ed. 1990)
Clarissa S. Holmes
R2,875 Discovery Miles 28 750 Ships in 10 - 15 working days

Behavioral medicine has blossomed as an area of systematic investiga tion during the past 10-20 years. Throughout its steady growth, there have been increasing interest and specialization in the study of neuro psychological and behavioral aspects of diabetes. This book attempts to capture and report exciting new developments in the study of both insulin-dependent (Type I) and non-insulin-dependent (Type II) dia betes mellitus. Accordingly, it is divided into two major sections. Physiological aspects of each disease, which differ significantly in pathophysiology and course, are discussed in separate medical over views that introduce each major section. These overviews are written by Drs. Tsalikian and Zimmerman, leading medical researchers in insulin and non-insulin-dependent diabetes, respectively. Each section also contains chapters describing neuropsychological and cognitive disease correlates, psychosocial patterns of adjustment, and treatment adher ence issues. Psychological aspects of insulin-dependent diabetes have been studied more extensively than non-insulin-dependent diabetes, perhaps because it is more often associated with graver medical compli cations. Therefore, there is a larger body of research to review and the first section has been divided into chapters on cognitive disease se quelae in populations of children and adults, separately. In his chapter, Dr. Ryan discusses developmental factors related to the unique sensi tivity of the brain to metabolic derangement. Dr. Holmes reviews studies of adults with diabetes and the cognitive correlates of both acute and chronic blood glucose disruption. Developmental disease is sues are further covered in Dr."

Virus Infections and Diabetes Mellitus (Paperback, Softcover reprint of the original 1st ed. 1987): Yechiel Becker Virus Infections and Diabetes Mellitus (Paperback, Softcover reprint of the original 1st ed. 1987)
Yechiel Becker
R2,870 Discovery Miles 28 700 Ships in 10 - 15 working days

This volume in the series Developments in Medical Virology deals with viruses involved in diabetes mellitus, a syndrome with a strong genetic background that causes damage to the regulation of insulin synthesis and function. Viruses were found either to cause or to stimulate diabetes mellitus in man and in animal models. The nature of the role of viruses is described by many of the scientists who participated in the original studies. To complete the picture, chapters were included that deal with the insulin gene, the secondary structure of the proinsulin and insulin receptor polypeptides, pancreatic Langerhans islets, and clinical considerations of the disease. The aim of Developments in Medical Virology is to elucidate processes involving viruses as pathogens of cells and organisms, with special attention to human diseases. A number of volumes will be devoted to viruses affecting specific organs (e.g. brain, liver, etc.), while others will elaborate on the clinical experience in the use of antiviral drugs. The series is published in parallel with Developments in Molecular Virology, designed to present an analysis of molecular mechanisms implicated in virus infection and replicative processes. In addition, the series Developments in Veterinary Virology provides information on viruses causing diseases in animals, with special emphasis on aspects of interest to veterinarians.

Pharmacotherapy of Diabetes: New Developments - Improving Life and Prognosis for Diabetic Patients (Paperback, Softcover... Pharmacotherapy of Diabetes: New Developments - Improving Life and Prognosis for Diabetic Patients (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Carl Erik Mogensen
R4,375 Discovery Miles 43 750 Ships in 10 - 15 working days

Diabetes is a huge and growing healthcare worry, especially in Western countries. The treatment of both types - 1 and 2 - of this disease has changed radically over the past few years. This work provides an overview of all the changes that will come to be implemented in clinical practice. Summarizing all aspects of treatment, this book delineates the large amount of research work that has been completed over the last few years into the relief of complications in diabetes and vascular medicine in general.

Role of Physical Exercise in Preventing Disease and Improving the Quality of Life (Paperback, Softcover reprint of hardcover... Role of Physical Exercise in Preventing Disease and Improving the Quality of Life (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Vilberto Stocchi, Pierpaolo De Feo, David A. Hood
R1,505 Discovery Miles 15 050 Ships in 10 - 15 working days

The aim of this volume is to underline that promoting physical activity is crucial to preventing illness and maintaining our health, thus leading to a reduction in healthcare costs. Over the last decade studies have shown that physical exercise plays an important role in maintaining an individual's psycho-physical balance. Physical activity therefore helps in tackling today's major health challenges, including diabetes, high blood pressure, and cardiorespiratory diseases.

Overweight and the Metabolic Syndrome: - From Bench to Bedside (Paperback, Softcover reprint of hardcover 1st ed. 2006): George... Overweight and the Metabolic Syndrome: - From Bench to Bedside (Paperback, Softcover reprint of hardcover 1st ed. 2006)
George A Bray, Louisiana State University, Donna Ryan
R4,367 Discovery Miles 43 670 Ships in 10 - 15 working days

This timely book provides an overview of topics related to obesity. These include associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity. The volume covers evaluation guidelines, different approaches to treatment, including diet, exercise, behavior, drugs, and surgery to deal with the current world-wide obesity epidemic.

The Role of Aging in Atherosclerosis - The Sequestration Hypothesis (Paperback, Softcover reprint of hardcover 1st ed. 2003):... The Role of Aging in Atherosclerosis - The Sequestration Hypothesis (Paperback, Softcover reprint of hardcover 1st ed. 2003)
R. E. Tracy
R2,870 Discovery Miles 28 700 Ships in 10 - 15 working days

The cover of this book summarizes the central features of the sequestration hypothesis: Commonplace appearances seen in human coronary artery, fat stained in paraffin seetions by a new technique explained in Chapter Eleven, are arranged to suggest pathways of evolution toward atheroma. The hypothesis formulated and defended in the pages ofthis book is this: Fibroplasia progresses upward in column "a" from "la" to "3a" as a characteristic feature of aging. This starts sooner and progresses faster in men than in wornen. Numbers ofSMC's remain essentially constant so that fibroplasia per SMC steadily increases. The rise upward conveys an increasing propensity to sequester atherogenic lipids, causing transition rightward into column "b." Sequestered extracellular lipid then attracts fatty streak elements, especially foam cells and lyrnphocytes, to propel the arterial site rightward into column "c." Frame "lc" corresponds to the AHA Lesions Committee classification type IIb, the progression resistant fatty streak arising directly without prior lipid sequestration; this can progress to atheroma, but slowly after much delay, although extreme provocation can accelerate the process. Such progression is rightward toward atherorna with thin cap, not upward toward fibroplastic thickening. Frame "2c" corresponds to the AHA classification, type Ha, progression prone fatty streaks. These readily evolve into atheroma, again by horizontal progression.

Science and Practice of Pressure Ulcer Management (Paperback, 2006): Marco Romanelli, Michael Clark, George W. Cherry, Denis... Science and Practice of Pressure Ulcer Management (Paperback, 2006)
Marco Romanelli, Michael Clark, George W. Cherry, Denis Colin, Tom Defloor
R4,084 Discovery Miles 40 840 Ships in 10 - 15 working days

Only comprehensive reference book on pressure ulcers and their management

Only book in its field endorsed by the European Pressure Ulcer Advisory Panel, the leading European authority on pressure ulcers

The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism (Paperback, Softcover reprint of hardcover 1st... The Paraoxonases: Their Role in Disease Development and Xenobiotic Metabolism (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Bharti Mackness, Mike Mackness, Michael Aviram, Gyoergy Paragh
R4,362 Discovery Miles 43 620 Ships in 10 - 15 working days

Research into the paraoxonase (PON) multigene family has really only blossomed in the last 10 years. Before this time only PON1 was known and research was restricted to toxicologists investigating the metabolism of organophosphate insecticides and nerve gases and a few mad scientists searching for natural substrates.

Since this time two new members PON2 and PON3 have been discovered, all 3 PONs have been shown to act as antioxidants and the PON family has taken centre stage as major players in the development of a wide variety of diseases such as cardiovascular disease, diabetes mellitus, rheumatism, Alzheimer and many more while remaining important in determining organophosphate toxicity.

In September 2006 the 2nd International Conference on Paraoxonases took place in Hajduszoboszlo, Hungary, bringing together the world's foremost experts in the field. The current book is a distillation of the plenary lectures which took place at the meeting, resulting in a comprehensive up to date, state of the art review of current paraoxonase research."

Endocrine-Disrupting Chemicals - From Basic Research to Clinical Practice (Paperback, Softcover reprint of hardcover 1st ed.... Endocrine-Disrupting Chemicals - From Basic Research to Clinical Practice (Paperback, Softcover reprint of hardcover 1st ed. 2007)
Andrea C. Gore
R4,645 Discovery Miles 46 450 Ships in 10 - 15 working days

This book provides comprehensive coverage of the three most important themes in the field of Endocrine Disrupting Chemicals (EDC) research: the basic biology of EDCs, particularly their effects on reproductive systems; EDC effects on humans and wildlife, including biomedical considerations; and potential interventions and practical advice for dealing with the problem of EDCs.

Handbook of Diabetes Management (Paperback, Softcover reprint of hardcover 1st ed. 2005): Donna Zazworsky, Jane Nelson Bolin,... Handbook of Diabetes Management (Paperback, Softcover reprint of hardcover 1st ed. 2005)
Donna Zazworsky, Jane Nelson Bolin, Vicki Gaubeca
R3,901 Discovery Miles 39 010 Ships in 10 - 15 working days

The growing problem of diabetes presents difficult challenges for sufferers and for those in the healthcare professions, who are in the unenviable position of trying to convince patients to change their lifestyle "for their own good." Handbook of Diabetes Management provides practical knowledge and advice that can help you anticipate the challenges of working with these Patients. What's more, since the knowledge here is evidence-based, you can assure your patients that the guidelines you're presenting to them have been shown to be effective. This guide takes into account the complexity of the disease, the diversity of the populations it affects, and the continued improvement of care systems. It discusses the origins of diabetes and medication management and treatment, then presents advice based on the latest research findings on: -behavioral health and self-management issues and interventions -tips for patients dealing with issues such as travel, surgery, and foot care -treating specific patient populations including Latinos, Native Americans, rural communities, and the uninsured -case studies from successful, replicable programs Also addressing the business aspects of diabetes care related to such areas as legal and regulatory issues and health policy initiatives, Handbook of Diabetes Management, brings you practical insights based on the latest research. "This handbook book by expert professionals covers every aspect of diabetic care. It is a sound, evidence-based, culturally informative, practical approach to diabetes prevention and disease management." -Kathleen Lambert, BSN, RN, JD, from the Foreword

Type 2 Diabetes Mellitus: - An Evidence-Based Approach to Practical Management (Paperback, Softcover reprint of hardcover 1st... Type 2 Diabetes Mellitus: - An Evidence-Based Approach to Practical Management (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Mark N Feinglos, Mary Angelyn Bethel
R6,456 Discovery Miles 64 560 Ships in 10 - 15 working days

In this practical book, the authors of each chapter have synthesized the currently available evidence regarding specific issues in diabetes care. The chapters have been written by an interdisciplinary team of scientists and medical professionals. Such an approach emphasizes the need for collaboration in the care of any individual with diabetes and in the effort to find new therapies for the disease. This reference provides practical guidance in a single resource.

Autoimmune Diseases in Endocrinology (Paperback, Softcover reprint of hardcover 1st ed. 2008): Anthony P. Weetman Autoimmune Diseases in Endocrinology (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Anthony P. Weetman
R6,859 Discovery Miles 68 590 Ships in 10 - 15 working days

This is a comprehensive and novel text that examines key features that predispose individuals to autoimmune diseases. The first section details the basic mechanism of autoimmunity and examines immunogenetic and environmental factors in autoimmunity. The next section examines autoimmune thyroid disease. The third section takes a look at Type 1 diabetes mellitus. In the final section, authors explain other autoimmune endocrinopathies.

Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome (Paperback, Softcover reprint of hardcover 1st ed.... Oxidative Stress, Inflammation and Angiogenesis in the Metabolic Syndrome (Paperback, Softcover reprint of hardcover 1st ed. 2009)
Raquel Soares, Carla Costa
R4,348 Discovery Miles 43 480 Ships in 10 - 15 working days

Metabolic Syndrome (MS) is a highly prevalent condition in developed countries and is a cluster of several risk factors for type 2 diabetes and cardiovascular disease that includes increased body mass index/waist circumference, visceral obesity, insulin resistance, hyperclycaemia, dyslipidaemia and hypertension, which are all major causes of morbidity and death. This volume provides a critical review and discussion of the knowledge gathered on MS and analyzes the interplay between oxidative stress, chronic inflammation and angiogenesis features. There is a special focus on recent discoveries and progress toward possible therapeutic strategies, such as the role of glucose transporters within MS; the effects of polyphenols as anti-oxidant, anti-inflammatory and anti-angiogenic compounds. The role of NFkB, nitric oxide synthases, hypoxia-inducible factors, and many other molecules that play a part in the development of oxidative stress and inflammation as well as angiogenesis is also covered. This book fills the gap between basic science and medical care, and provides the reader with the skills to apply rigorous basic science to clinical settings of metabolic syndrome-associated disorders.

Pancreatic Beta Cell in Health and Disease (Paperback, Softcover reprint of hardcover 1st ed. 2008): Susumu Seino, Graeme I Bell Pancreatic Beta Cell in Health and Disease (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Susumu Seino, Graeme I Bell
R5,611 Discovery Miles 56 110 Ships in 10 - 15 working days

The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This metabolic hormone plays a central role in the maintenance of glucose homeostasis. This book provides a comprehensive review of the beta cell in health and disease. The book 's primary aim is to encourage investigators to become actively involved in diabetes research and the search for new approaches to prevent and treat diabetes.

Type 1 Diabetes - Etiology and Treatment (Paperback, Softcover reprint of hardcover 1st ed. 2003): Mark A. Sperling Type 1 Diabetes - Etiology and Treatment (Paperback, Softcover reprint of hardcover 1st ed. 2003)
Mark A. Sperling
R6,474 Discovery Miles 64 740 Ships in 10 - 15 working days

A concise survey by physicians and researchers of the latest thinking about the causes of diabetes and the best approaches to treating its acute and chronic complications. The authors pay special attention to explaining the molecular basis of diabetes and its complications, as well as to the many recent developments in whole pancreas and islet cell transplantation, including the means for avoiding the rejection of transplanted islets.

Diastolic Heart Failure (Paperback, Softcover reprint of hardcover 1st ed. 2008): Otto A. Smiseth, Michal Tendera Diastolic Heart Failure (Paperback, Softcover reprint of hardcover 1st ed. 2008)
Otto A. Smiseth, Michal Tendera
R3,166 Discovery Miles 31 660 Ships in 10 - 15 working days

Heart failure is the biggest killer in the western world, and the prevalence is expected to increase due to aging of the population. Over the past decade there has been an increasing awareness of left ventricular (LV) diastolic dysfunction as a mechanism of congestive heart failure. This book provides the clinician with essential insights into the epidemiology and aetiology of diastolic heart failure, and will enable them to understand how the condition can be diagnosed. Furthermore, the book will provide insights in cardiac function that are needed to perform and interpret the diagnostic tests, and to provide some guides to treatment choices.

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