The demands of caring for a child with diabetes can often become exhausting and overwhelming. Diabetes Distress and Burnout for Parents and Carers provides support to those caring for a child with type 1 diabetes. This booklet helps readers to identify the symptoms of burnout, understand what triggers them, and learn what steps they can take to improve their symptoms and build resilience. Featuring quotes from caregivers who have experienced and overcome burnout and practical tools to manage and ease the symptoms alongside guidance on what to do if a relapse occurs. In addition, the booklet highlights the support available and provides helpful links to sources and organisations where readers can go for further information on diabetes. An ideal resource for caregivers of children and young people with type 1 diabetes, as well as the wider diabetes healthcare team, including clinical psychologists, specialist nurses, endocrinologists and general practitioners.

Highly Commended in the 2004 BMA Medical Book Competition (Endocrinology)

Judges' summary:
"Beautifully and clearly written to appeal to all levels of healthcare professional knowledge. A wealth of practical experience is freely donated to the reader in a friendly and accessible way. Each section is easily found and any member of the team could care for a patient with that particular problem to a high standard with this book in their hand. I would unhesitatingly recommend to all diabetes doctors - both senior and junior, and every diabetes unit should have a copy. This new edition is excellent and should be considered for an award."

"Diabetes and its Management," Sixth Edition, continues to provide a practical clinical guide to the management of patients with diabetes. The author team has been expanded and now also includes a Nurse Practitioner specialising in diabetes to provide the nursing perspective. It is a concise manual that distils the essential recent developments into practical advice.

This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers. The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy. Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.

This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.

Eric was 150 pounds overweight, depressed, and sick. After a lifetime of failed diet attempts, and the onset of type 2 diabetes due to his weight, Eric went to a new doctor, who surprisingly prescribed a shelter dog. And that's when Eric met Peety: an overweight, middle-aged, and forgotten dog who, like Eric, had seen better days. The two adopted each other and began an incredible journey together, forming a bond of unconditional love that forever changed their lives. Over the next year, just by going on walks, playing together, and eating plant-based foods, Eric lost 150 pounds, and Peety lost 25. As a result, Eric reversed his diabetes, got off all medication, and became happy and healthy for the first time in his life-eventually reconnecting with and marrying his high school sweetheart. WALKING WITH PEETY is for anyone who is ready to make a change in his or her life, and for everyone who knows the joy, love, and hope that dogs can bring. This is more than a tale of mutual rescue. This is an epic story of friendship and strength.

This book covers a wide range of topics concerning human tear based science, starting from basics such as the normal composition of tears and moving up to novel disease detection platforms. The entire approach is pioneering, as tears are beginning to be recognized as the most invaluable non-invasive tool in diagnostics. Interestingly, the concept is not restricted to ocular diseases: In recent years, tear diagnostics is increasingly being tapped even for cancer detection. Hopefully, non-invasive tear diagnostics will eventually replace today's invasive disease detection and monitoring techniques. Previous literature on tear diagnostics has been restricted to scientific journal articles, most of which dealt with a single tear constituent, such as a protein. This book offers a far more comprehensive and handy 'reference guide,' presenting both basic and advanced information and data. Accordingly, it will be useful for researchers in academia and the pharmaceutical industry, as well as healthcare professionals and diagnostic kit developers.

Every three or four minutes someone in the US receives a diagnosis of diabetes. But, healthy eating - alongside other lifestyle changes and, if necessary, medication - may prevent diabetes from developing and dramatically reduces the risk of diabetic complications such as heart disease, amputations and blindness. This book shows how to avoid the worse ravages of this disease. Topics include: types of diabetes; the pancreas and how it controls blood sugar; medication; controlling carbohydrates; guidelines for healthy eating and using supplements safely.

On the increase worldwide, diabetes is well recognized as a complex and challenging condition. This pocket-sized guide puts diabetes information at your fingertips, equipping you with the essential knowledge and skills to deliver effective day-to-day diabetes care competently and confidently. The Nursing & Health Survival Guides have evolved - take a look at our our app for iPhone and iPad.

Patient empowerment is examined as a multi-dimensional factor influencing the use of diabetes self-management apps. The research design includes three studies conducted in Singapore. Study 1 examines how features of diabetes self-management apps correspond with theoretical indicators of empowerment, as well as app quality. Study 2 uses semi-structured face-to-face interviews with diabetes patients to draw first conclusions about the relevance of empowerment for diabetes app use. Study 3 includes an online patient survey, and uses cluster analytical methods to test the preliminary Study 2 results (typology of app use), as well as binary logistic regression to compare the strength of influence of various anteceding factors on the likelihood of diabetes app use. The studies show that especially the support by private social patient networks and the medical specialties of supervising physicians play a crucial role for technology-supported self-management.

Tommy is a happy young dinosaur with not a care in the world. One day he begins to feel unwell, so his friend, Pterry, takes him to see the Witch Doctor. The Witch Doctor discovers that Tommy has Type 1 Diabetes and shows him how to test his blood sugar levels, take insulin and what to do when his blood sugars go too low. With the Witch Doctor’s help Tommy is able to go on to lead a normal and healthy life, while still having fun with his friends. Filled with colourful illustrations, this book aims to demystify diabetes and help children to come to terms with a life-changing illness.

UPDATED 2018. This substantially updated new edition offers detailed help on cooking for people with diabetes, including an extensive introduction that helps to explain the condition and offers advice on all aspects of nutrition as well as weight management and exercise. Guidance is given on how to live with diabetes, with advice on managing the condition, alleviating the symptoms, controlling your weight and reducing medication, and bringing together the latest thinking on dietary and lifestyle advice to help understand the condition while offering clear guidelines on what and when to eat. There is then a fantastic selection of tempting but healthy recipes, to help tailor food intake to individual requirements, with recipes to inspire diabetic cooks and enable them to continue to enjoy food with family and friends, with breakfast suggestions, snacks, light meals, main courses, and even puddings and desserts. There is a special section on diabetes in children, as well as advice and support for how to manage the condition through puberty, pregnancy and through the ageing process. The 150 recipes provide everything that is needed for a varied and enjoyable diet, with recipes that friends and family will enjoy such as Roasted Chicken with Mediterranean Vegetables, Grilled Mackerel with Spicy Dahl, and Wild Mushroom and Fontina Tarts. Each recipe comes with complete nutritional notes Fully illustrated with over 650 photographs, this book will be welcome reading for anyone living with diabetes.

This book provides a pioneering approach to modeling the human diabetic patient using a software agent. It is based on two MASc (Master of Applied Science) theses: one looking at the evolution of the patient agent in time, and another looking the interaction of the patient agent with the healthcare system. It shows that the software agent evolves in a manner analogous to the human patient and exhibits typical attributes of the illness such as reacting to food consumption, medications, and activity. This agent model can be used in a number of different ways, including as a prototype for a specific human patient with the purpose of helping to identify when that patient's condition deviates from normal variations. The software agent can also be used to study the interaction between the human patient and the health care system. This book is of interest to anyone involved in the management of diabetic patients or in societal research into the management of diabetes. The diabetic patient agent was developed using the Ackerman model for diabetes, but this model can be easily adapted for any other model subject with the necessary physiological data to support that model.

In this incredible resource, diabetics will learn to manage their blood-sugar levels with healthy recipes that are low in sugars and balanced in carbs, fiber, fats and proteins. Mary Ellen Phipps, a registered dietician nutritionist who has had Type 1 diabetes since childhood, has a personal understanding of how eating while diabetic can feel restrictive and daunting, which is why her recipes not only regulate blood sugar levels and taste delicious, but shows diabetics how to enjoy their favourite foods in the way that is best for their bodies. Recipes cover every course from breakfast to dinner to dessert, so readers never have to scramble to find healthy, great tasting meals any time of the day. Tackle the morning with blood sugar balancing breakfasts like Blueberry Cheesecake Overnight Oats, nibble on safe snacks like No Bake Coconut Cashew Energy Bites, and enjoy filling dinners like 30-Minute Garlic Lamb Lollipops and Lemon Pepper Salmon. You'll even be able to indulge in desserts like Crispy Pistachio Chocolate Bark and Peanut Butter Fudge Brownies with Mary's expert techniques for creating low-sugar treats that still taste great! In addition to these tasty recipes, Mary also provides professional and personal tips for managing diabetes through food and lifestyle changes, so readers develop a new, all-encompassing approach to positively navigating their condition. This book has 60 recipes and 60 photographs.

Living with diabetes is a balancing act of monitoring blood glucose, food intake, and medication. It makes sense that individuals who have diabetes do best when they understand their condition and how to control it. The Johns Hopkins Guide to Diabetes is a comprehensive and easy-to-read guide to this complex condition, answering questions such as: What are the differences between Type 1 and Type 2 diabetes? How are the different forms of this disease treated? Can gestational diabetes become a permanent condition? Can diabetes ever be managed successfully with diet and exercise alone? The second edition of this valued resource includes up-to-date information on: how diabetes is diagnosed; the two types of diabetes; the role of genetics; improvements in blood glucose measurement; good nutrition and regular exercise; insulin and non-insulin medications; insulin pumps; the emotional side of diabetes; how families are affected and how they can help; what to do if diabetes affects your work; and complications from head to toe. Written by a team of Johns Hopkins diabetes specialists, this authoritative guide will help people who have diabetes work effectively with their care team to control their diabetes and maintain good health.

The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country's prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant.

DDDDDDDDDDDD Effective management logically follows accurate diagnosis. Such logic often is difficult to apply in practice. Absolute diagnostic accuracy may not be possible, particularly in the field of primary care, when management has to be on analysis of symptoms and on knowledge of the individual patient and family. This series follows that on Problems in Practice which was con cerned more with diagnosis in the widest sense and this series deals more definitively with general care and specific treatment of symp toms and diseases. Good management must include knowledge of the nature, course and outcome of the conditions, as well as prominent clinical features and assessment and investigations, but the emphasis is on what to do best for the patient. Family medical practitioners have particular difficulties and advantages in their work. Because they often work in professional isolation in the community and deal with relatively small numbers of near-normal patients their experience with the more serious and more rare conditions is restricted. They find it difficult to remain up-to-date with medical advances and even more difficult to decide on the suitability and application of new and relatively untried methods compared with those that are 'old' and well proven. vii Their advantages are that because of long-term continuous care for their patients they have come to know them and their families well and are able to become familiar with the more common and less serious diseases of their communities."

Changing when you eat, sleep and exercise can help you to treat, manage - and even reverse - type 2 diabetes and prediabetes. Circadian rhythms are personal biological clocks that exist in each one of our cells and they influence every aspect of our health. The Circadian Diabetes Code now applies this cutting-edge science to tackling type 2 diabetes. Combining circadian rhythms with intermittent fasting - the worldwide phenomenon launched in Dr Panda's lab - you'll find out how to use this unique protocol to take back control of diabetes and achieve life-long health. - Discover the best way to use intermittent fasting to lose weight - Learn when to exercise to optimise blood glucose levels - Identify ideal times to eat meals and take medication - Why the science of circadian rhythms can help you reverse type two diabetes

This book describes the surgical bariatric procedures most frequently performed worldwide and examines their evolution in recent years both within Italy and internationally. For each operation, indications, the surgical technique, potential complications, and the outcomes with respect to weight and obesity-associated comorbidities are presented. In view of the significant failure rate revealed by studies on the long-term results of bariatric surgery, the problem of weight regain and revision surgery are also discussed in detail, covering the different types of revision, conversion to other procedures, and the main outcomes. In addition, individual chapters focus on selected topics of importance. The role of bariatric surgery in the cure of type 2 diabetes ("diabetes surgery") is discussed and the debate over the significance of gastroesophageal reflux disease and hiatal hernia for choice of procedure is summarized. Finally, the most common endoluminal procedures, which have been gaining in importance, are described and other bariatric operations, outlined.

This comprehensive volume discusses in vitro laboratory development of insulin-producing cells. It encompasses multiple aspects of islet biology-from embryonic development and stem cell differentiation to clinical studies in islet transplantation, regulation of islet beta-cell regeneration, pancreatic progenitors, mathematical modelling of islet development, epigenetic regulation, and much more. The chapter authors represent leading laboratories from around the world who contribute their international perspectives and global expertise. Collectively, they provide the reader with a concise yet detailed knowledge of processes and current developments in islet regenerative biology. Pancreatic Islet Biology, part of the Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers and clinicians in stem cells or endocrinology, especially those focusing on diabetes.

'An honest and fascinating account of the journey that Tom made from discovering he was a type 2 diabetic to doing something about it. This book will change lives.' Michael Mosley, on The Sunday Time's bestseller Downsizing From the bestselling author of Downsizing, a guide to losing weight - and keeping it off - as well as improving health, from someone who has successfully done both, Lose Weight 4 Life outlines the programme Tom Watson followed for his own remarkable 8-stone (50kg) weight loss. Divided into 4 sections - Motivation, Movement, Measurement and Maintenance - it includes relatable examples of Tom's own, often bumpy, journey to better health, which saw him transform from someone who mindlessly hoovered up entire packets of biscuits at one go and had to rummage in the XXXL bin for exercise gear into someone who rowed the length of the UK. Packed with practical advice backed up by the latest research, Lose Weight 4 Life demonstrates that it is never too late to turn things around, even if you are someone who has failed umpteen times before.

This book addresses all aspects of white coat hypertension – the phenomenon of raised blood pressure in a medical setting yet not elsewhere – from its history to its pathophysiology, diagnosis and treatment. White coat hypertension is a common condition, accounting for 30–40% of the overall hypertensive population. While many studies have addressed this condition, controversy still exists over whether it causes an increased risk to sufferers and should be treated. In the volume neurogenic and non-neurogenic mechanisms are discussed and the significance of various predictive factors, evaluated. The association of white coat hypertension with dysmetabolic risk factors, new-onset diabetes and other conditions is carefully reviewed. Further chapters consider the occurrence of asymptomatic organ damage and cardiovascular outcomes in affected patients and helpful guidance is also provided on the controversial issue of when to treat and when not to treat. White Coat Hypertension is based largely on work done during the past 30 years by renowned researchers working in Milan, who have made key contributions in improving knowledge of the condition and whose work is well known across the world.

The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity, distribution of body fat and weight loss, as well as the mechanisms linking excess adiposity to various co-morbidities. Adipose Tissue and Adipokines in Health and Disease, Second Edition contains updated chapters from the previous volume but as the field has evolved, some areas covered in the first edition have been refocused to address the new knowledge. The volume is divided in four sections: the first two deal with basic adipose tissue and adipokine biology, while the last two address the problem of obesity and alterations in adipose tissue function from an epidemiological and clinical standpoint. The chapters are written by experts in their fields and include the most up to date scientific information. Adipose Tissue and Adipokines in Health and Disease, Second Edition is a useful resource for physicians interested in adipose tissue biology and basic scientists who want to know more about applied aspects of the field. The book targets endocrinologists, residents and fellows, internists, nutritionists and general practitioners who are exposed to an ever-expanding obese population.