Your ten-week plan to avoid the onset of diabetes

A diagnosis of pre-diabetes is certainly a wakeup call, but it is not a life sentence of daily medication and having to live without your favorite foods. Managing pre-diabetes is about common sense and moderation, not deprivation. "The Everything Guide to Managing and Reversing Pre-Diabetes, 2nd Edition" can help you find ways to alter your lifestyle and avoid type 2 diabetes. Inside, you'll find helpful tips on lifestyle changes, along with recipes for delicious, healthy meals your whole family will love, like:

• Buttermilk pancakes
• Rich and creamy sausage-potato soup
• Soy and ginger flank steak
• Grilled haddock with peach-mango salsa
• Walnut chicken with plum sauce
• Kasha-stuffed red peppers
• Cranberry pecan biscotti
• Chocolate cheesecake mousse

While the 21st century insulin crisis provokes protest and political dialogue, public conception of diabetes remain firmly unchanged. Popular media representations portray diabetes as a condition couched in lifestyle choices. In the groundbreaking volume (Un)doing Diabetes, authors destabilize depictions so powerful, so subtle, and so unquestioned, that readers may find assertions counterintuitive. (Un)doing Diabetes is the first collection of essays to use disability studies to explore representations of diabetes across a wide range of mediums- from Twitter to TV and film, to theater, fiction, fanfiction, fashion and more. This disability studies approach to diabetes locates individual experiences of diabetes within historical and contemporary social conditions. In undoing diabetes, authors deconstruct assumptions the public commonly holds about diabetes, while writers doing diabetes present counter-narratives community members create to represent themselves. This collection will be of interest to scholars, activists, caregivers, and those living with diabetes.

Early detection of sub-clinical autonomic dysfunction is of vital importance in patients with diabetes mellitus (DM) for the prevention of subsequent serious adverse consequences. Reduction in heart rate variability (HRV) is now regarded as the earliest indicator of cardiovascular dysregulation in DM. HRV has traditionally been quantified using linear measures, which describe the magnitude of RR interval oscillations, but are insufficient to characterise complex heart rate dynamics. While HRV is mostly mediated by parasympathetic nervous system, beat-to-beat blood pressure recordings may provide information regarding sympathetic activity. A variety of novel measures has been developed to quantify non-linear features of cardiovascular signals, providing information on the complexity of the dynamical system involved in the genesis of these short-term fluctuations. In this book, it is demonstrated that novel non-linear methods are often more sensitive to autonomic dysregulation than linear methods and therefore may improve the diagnostic power of cardiovascular variability analysis for cardiovascular autonomic neuropathy in DM. Our data indicate that cardiovascular dysregulation progresses in relatively short time frames, depending on the history of DM. Further, its progression appears to be associated with glycemic control. Different methods of cardiovascular variability analysis can provide mutually independent information and therefore should be used simultaneously for a comprehensive analysis of autonomic dysfunction to identify patients at risk for autonomic neuropathy.

This book provides a concise yet comprehensive resource on Diabetic Kidney Disease. Similar to the previous edition, the book reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features, and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are also covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease, 2e is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

Glucose Monitoring Devices: Measuring Blood Glucose to Manage and Control Diabetes presents the state-of-the-art regarding glucose monitoring devices and the clinical use of monitoring data for the improvement of diabetes management and control. Chapters cover the two most common approaches to glucose monitoring-self-monitoring blood glucose and continuous glucose monitoring-discussing their components, accuracy, the impact of use on quality of glycemic control as documented by landmark clinical trials, and mathematical approaches. Other sections cover how data obtained from these monitoring devices is deployed within diabetes management systems and new approaches to glucose monitoring. This book provides a comprehensive treatment on glucose monitoring devices not otherwise found in a single manuscript. Its comprehensive variety of topics makes it an excellent reference book for doctoral and postdoctoral students working in the field of diabetes technology, both in academia and industry.

A clear explanation of the cause, diagnosis, and treatment of diabetes Written for a broad range of readers, including students, researchers, policymakers, health care providers, and diabetes patients and caregivers, this book explains the underlying biochemistry and physiology of diabetes mellitus. Each chapter contains a glossary that defines key terms, a summary that highlights essential concepts discussed in each section of the chapter, as well as a set of simple problems to help readers gain a richer and deeper understanding of diabetes, from its history to treatment options. Understanding Diabetes begins with an overview of the disease, its worldwide prevalence and cost, and its connection to the global obesity epidemic. The author then explores the history of diabetes, including the first documented description of the disease dating back to 3400 BCE in Ancient Egypt. The next chapter, A Glucose Metabolism Primer, sets forth the pathways for the metabolism of glucose. Next, the book covers: * Regulation of glucose metabolism and glucose metabolism gone wrong * Diabetes classification system * Diagnosis, including current laboratory tests * Complications, such as retinopathy, neuropathy, and cardiovascular disease * Hereditary transmission * Prevention and treatment, including emerging research Although a cure has still not been found, this book demonstrates that researchers are continuing to make major breakthroughs on all fronts in the fight against diabetes, including a better understanding of its causes and an improved ability to diagnose and treat the disease.

Living with diabetes is a balancing act of monitoring blood glucose, food intake, and medication. It makes sense that individuals who have diabetes do best when they understand their condition and how to control it. The Johns Hopkins Guide to Diabetes is a comprehensive and easy-to-read guide to this complex condition, answering questions such as: What are the differences between Type 1 and Type 2 diabetes? How are the different forms of this disease treated? Can gestational diabetes become a permanent condition? Can diabetes ever be managed successfully with diet and exercise alone? The second edition of this valued resource includes up-to-date information on: how diabetes is diagnosed; the two types of diabetes; the role of genetics; improvements in blood glucose measurement; good nutrition and regular exercise; insulin and non-insulin medications; insulin pumps; the emotional side of diabetes; how families are affected and how they can help; what to do if diabetes affects your work; and complications from head to toe. Written by a team of Johns Hopkins diabetes specialists, this authoritative guide will help people who have diabetes work effectively with their care team to control their diabetes and maintain good health.

Diabetic neuropathy is amongst the most common of the late complications of diabetes, affecting up to 50% of older patients with Type 2 diabetes. It can result in disabling neuropathic pain, lower extremity amputations and troublesome autonomic neuropathies (gastroparesis, erectile dysfunction, sudden cardiac death and so forth). With the rising incidence of diabetes the prevalence of neuropathy is also likely to increase. Over recent years, there have been new advances in our understanding and treatment of diabetic neuropathies and the problems associated with the disease.

Diabetes and the Kidney provides endocrinologists and nephrologists of all levels with expert clinical diagnosis and management guidance for this extremely common diabetic complication.

Practical and accessible, chapters contain text features such as case histories, potential pitfall boxes, key points, management algorithms, and useful weblinks to fully engage the reader and provide expert guidance to help clinicians best manage their patients. In addition, all relevant international society guidelines and recommendations are fully included.

After an initial analysis of the epidemiology and pathogenesis of kidney complications in diabetes, it quickly moves on to the following core sections:

- Special Situations, Risk factors and Complications - examining diabetic nephropathy in relation to each other diabetic complication, ie cardiovascular disease- Prevention and Therapy - focusing on the most up to date information regarding prevention, diagnosis, treatment, and management of kidney disease in diabetes.

Expertly edited, and with contributions from an experienced international team, Diabetes and Kidney Disease will be the perfect tool to consult when managing diabetic patients with associated kidney problems.

Through healthy eating and regular exercise, professional chef Lyndon Wissart managed to reverse, control and cure his type 2 diabetes in 105 days, naturally without medication.This book shares his journey for the first time. Read his secret and discover yours. It could be a life-changing experience for you and your family, colleagues and friends.Lyndon is an inspiration for the more than 4.5 million diabetics in the UK alone and the 850,000 people who are undiagnosed worldwide.

This book considers the aetiological factors that render renal patients at risk of infection and covers the infectious complications of the major modalities of renal replacement therapy. The book has been written by a combination of microbiologists, clinical scientists and clinicians active in the care of kidney patients at all stages in their treatment from chronic renal insufficiency through dialysis and on to transplantation. It brings together a large body of clinical and scientific material to help clinicians manage infectious complications of kidney disease. As far as is possible a clinical chapter is balanced by a chapter dealing with pathophysiology.

The book is divided in to three sections: Basic Mechanisms, Infectious Complications of Common Renal Conditions, Renal Failure and Transplantation, and Prevention and Management.

The uraemic condition as a state of immunosupression is discussed to set the scene for why renal patients are prone to so many diverse infections. Increasingly potent immunosuppressive drugs are being deployed in a variety of primary conditions and also to prevent renal allograft rejection. The mechanisms by which these drugs predispose to infection are discussed. A chapter deals specifically with peritoneal defence mechanisms of critical importance in the management of infection complicating continuous ambulatory peritoneal dialysis.

The second section of the book deals specifically with infectious complications in defined situations. For example, diabetes mellitus is discussed in detail as this is now the major cause of endstage chronic renal failure. Infectious complications of glomerulonephritis and vasculitis are discussed, and this relates to the effects of the potent immunosuppressive agents now deployed. Specific chapters are devoted to infectious complications of peritoneal dialysis and haemodialysis including a chapter on mucormycosis. Hepatitis B and Hepatitis C have each been given a chapter and the impact of these hepatitis viruses on the renal patient from chronic renal failure through dialysis to transplantation is described. Infectious complications of transplantation follows and reviews the common infections as well as presenting some new data on viral induced tumours.

In the final section of the book, prevention of infection is discussed with particular emphasis to vascular access and the care of the uraemic ischaemic/diabetic foot. The general principles relating to limiting the spread of infection within the Renal Unit are discussed in detail. Increasing patient mobility and travel requires that travel and vaccination in renal patients are discussed. The book ends with a practical chapter on prescribing advice for the use of common anti-microbial agents.

This book will be of value to all those involved in the care of this vulnerable group, specifically nephrologists, renal transplant surgeons and physicians and diabetologists.

This new edition of the popular and market-leading Diabetes in Old Age features up-to-date and comprehensive information about the key aspects of managing older people with diabetes, predominantly type 2 diabetes. With a strong evidence-based focus throughout, the entire range of issues surrounding diabetes and its many complications are covered, each with a clear focus on how they relate directly to the older patient. Varying approaches to optimizing diabetes care in the community, primary care and secondary care health care arenas are presented, and the importance of comprehensive functional assessment is emphasized. Coverage of areas unique to an ageing population of older people with diabetes such as falls management, frailty and sarcopenia, and cognitive dysfunction form a key cornerstone of the book. In every chapter, best practice points and key learning outcomes are provided, as well as published evidence bases for each major conclusion. Diabetes in Old Age, 4th edition is essential reading for diabetologists and endocrinologists, diabetes specialist nurses, primary care physicians, general physicians and geriatricians, podiatrists and dieticians with an interest in diabetes, as well as all health professionals engaged in the delivery of diabetes care to older people.

This book covers the complexity of diabetes and related complications and presents the socio-economic burden of the disease, taking into account the rising prevalence reaching pandemic proportions and the associated costs. Factors causing high diabetes prevalence and the influence of the pharmaceutical industry are evaluated and solutions for sustainable diabetes care with limited resources are provided, including national focus on providing cost-effective diabetes treatment, nutrition and physical activity, structured diabetes education and centralized National e-Health System. Moreover, elaboration of long-term efforts to curb the diabetes burden through prevention activities are presented in this book. Managing Diabetes in Low Income Countries represents an essential guide for diabetes care clinicians and researchers, medical students and clinicians in training, diabetes policy makers, regulatory authorities, international diabetes and patient organisations all of whom are involved in current clinical practice for diabetes management.

Clinical nephrology is confronted with an emerging medical catastrophy of international proportions; endstage renal failure in patients with type 2 diabetes. Based on a number of recent studies it has become apparent, that nephrology in type 2 diabetes is a preventable condition, at least in principle. It is for this reason that it appeared timely to summarize the current state of knowledge concerning nephropathy in type 2 diabetes giving an update on the predisposing factors on which interventions are of proven benefit and on the accepted standards of management of such patients. This concise monograph is addressed not only to nephrologists, but also diabetologists and general practitioners. It is hoped that it will help to improve clinical outcomes in the future.

The book explores both the clinical presentation of serious diabetic emergencies (like ketoacidosis, hyperosmolar coma, and severe hyper and hypoglycemia) that consultants and hospital staff encounter in practice and the best methods of both managing the emergencies and also administering follow-up guidance/care. All chapters are clearly structured to highlight: definition of emergency; epidemiology; potential causes, diagnosis, clinical management (including problem areas), follow-up management/care; and patient advice.
There are case studies to aid clinical understanding, as well as 5-7 multiple choice questions and several key points/take-home message boxes in every chapter.

Diabetes mellitus is a major public health problem affecting over 415 million people in the world. Extensive research over the decades and the recent discovery of new medicines have revolutionized our understanding and treatment of both type 2 diabetes and type 1 diabetes mellitus. This book contains selected topics that describe recent advances in research, and state of the art treatment of the two types of diabetes mellitus and their complications. The topics encompass epidemiology and pathogenesis of diabetes, clinical features, diagnosis and treatment of diabetes and related complications. The chapters contain essential background materials, as well as recent advances in researches in different aspects of diabetes mellitus. The books is expected to be useful for researchers, research students, as well as for the clinicians engaged in diabetes care and diabetes research.

This book presents essential information on biomechanical features of the diabetic foot, which could help to minimize the risk of future diabetic foot problems. India has recently been classified as the 'diabetic capital' of the world. Type 2 diabetes mellitus has become a serious concern for Indian society, where the prevalence rate is increasing exponentially. Similarly, the comorbidities and foot complications of type 2 diabetes mellitus are worsening day by day. Of all complications, diabetes peripheral neuropathy is the most common, and leads to foot deformities, pain, altered sensation, loss of foot arch, etc. The ultimate fate can even be gangrene and amputation. Accordingly, foot complications of diabetes represent a pressing medical issue. Sharing insights into diabetic foot syndrome, its causative factors, prevention and management, this book offers a valuable resource for medical and paramedical students, researchers, podiatrists, surgeons, and physicians alike.

This book combines the reference material of a nephrology textbook with the everyday relevance of a clinical handbook. This second edition develops and expands upon the success of the first. All the content has been updated and entirely new chapters on acid-base disorders and stone disease have been added. Understanding Kidney Diseases includes over 60 real-life case studies and is illustrated with over 200 figures. Readers can test their knowledge with a bank of multiple-choice questions and put it into practice by answering questions that patients frequently ask. The book provides all that students, residents and fellows need in order to approach a patient with a kidney problem with confidence.

The bestselling, big-hearted and down-to-earth chefs, The Hairy Bikers, return with 80 of their very best Dieter recipes. Contains previously published recipes - brought together in a collection that's designed to help tackle type 2 diabetes for the first time.

In this paperback, first of a new healthy eating series, the Hairy Bikers prove that you can still eat your favourite foods while staying healthy and losing weight. With their delicious, low-cal versions of traditional classics and family favourites, the Bikers take the deprivation out of restrictive diets and are here to help you shift the pounds.

This book is full of information to digest and dieting hits to enjoy. The Bikers also share their own personal stories of their battles against type 2 diabetes, and hope to inspire readers as they start their own weight loss journey.

Whether you've been struggling with type 2 diabetes for years or have recently been diagnosed, there's no better time to take action and make a change.

This book comprehensively describes the association between metabolic syndrome and pancreatic cancer progression, and the mechanism of action and target definition with a view to drug discovery. Metabolic syndrome, which includes adnominal obesity, hypertension, dyslipidemia, and hyperglycemia, has recently been shown to play an important role in the etiology and progression of various cancers. Further, obesity and diabetes have been associated with an increased incidence of gastric cancers. The book reviews the key biological mechanisms underlying the association between metabolic dysregulation, including obesity-associated enhancement of growth factor signaling, inflammation, and perturbation in pancreatic cancer cell growth and metastasis. It also illustrates the role of the inflammatory signaling pathway in metabolic diseases as well as tumor growth and explores the potential of these pathways as the rational targets for pancreatic cancer therapy. Lastly, the book offers a comprehensive description of the challenges associated with diabetes and pancreatic cancer therapy.

The incidence of diabetes is increasing worldwide at an alarming rate, and diabetic retinopathy is one of the most significant complications of diabetes. Packed with outstanding retinal photos, the second edition of this one-stop clinical manual offers a comprehensive overview of the diagnosis, treatment and long term management of patients with diabetic eye disease. Edited and authored by world-renowned experts from leading centres of excellence, A Practical Manual of Diabetic Retinopathy Management presents evidence-based guidance relevant for a global audience of health-care professionals, including diabetologists, ophthalmologists, retinal screeners, optometrists, ophthalmic nurses, GPs, and medical students.

A practical "how to" guide for multiple methods in metabolism, with a critical and objective discussion of strengths, limitations, and appropriate applications of the described methods.

Edited by the winner of the Oskar-Minkowski Prize of the EASD in 2006

Clinical trials in populations at risk of or with overt diabetes mellitus are being performed all around the world to test novel drugs and approaches to managing these diseases. During the last decade, new methods and techniques have been introduced - and are being developed further - that facilitate monitoring of metabolism and even diagnosis of certain defects in human metabolism. While some of these methods are restricted to research facilities, others are already used in clinical practice. The correct beneficial use of these methods requires knowledge of the nature of the techniques and their clinical relevance.

"Clinical Diabetes Research: Methods and Techniques" provides summaries of established state-of-the art-techniques and introduces the new technologies, evaluating their potential in clinical diabetes research. One section compares the efficacy of all metabolic tests that measure insulin action. Another section describes methods that allow quantification of whole body and intracellular metabolic fluxes relevant to diabetes research. The final section focuses on the planning and pitfalls of clinical studies in the field of metabolism. Each chapter throughout the book combines the theoretical basis of the approach with practical recommendations. There are further chapters on the design of clinical trials and ethical considerations.

The publication is timely in view of the impressive development of the methods and techniques with their application to understanding the pathophysiology of diabetes, insulin resistance syndromes, obesity, and the metabolic effects of treatment.

"Clinical Diabetes Research: Methods and Techniques" is of great relevance for researchers (from students and post-docs to principal investigators) in the field of human metabolism, clinical endocrinologists and diabetologists who are involved in clinical studies.

This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

This book covers a wide range of topics concerning human tear based science, starting from basics such as the normal composition of tears and moving up to novel disease detection platforms. The entire approach is pioneering, as tears are beginning to be recognized as the most invaluable non-invasive tool in diagnostics. Interestingly, the concept is not restricted to ocular diseases: In recent years, tear diagnostics is increasingly being tapped even for cancer detection. Hopefully, non-invasive tear diagnostics will eventually replace today's invasive disease detection and monitoring techniques. Previous literature on tear diagnostics has been restricted to scientific journal articles, most of which dealt with a single tear constituent, such as a protein. This book offers a far more comprehensive and handy 'reference guide,' presenting both basic and advanced information and data. Accordingly, it will be useful for researchers in academia and the pharmaceutical industry, as well as healthcare professionals and diagnostic kit developers.