This book tells the story of diabetes, from ancient times to today, and provides an accessible introduction to the cause, treatment, and impact of the disease.Diseases have a history, and understanding that history helps us understand how best to treat and control disease today. Today's students are confronted with a panoply of often-frightening illnesses and afflictions - the Biographies of Disease series provides necessary information to understand the origin of various maladies, how they impact contemporary society, and how doctors and researchers from around the world are fighting to devise treatments to alleviate or cure these diseases.This volume, Diabetes, covers a disease that has been a common affliction from the beginning of recorded history, but has been increasing in its impact because of changes in diet and exercise, especially among the young. Diabetes examines all aspects of this disease, including: the diagnosis and treatment of diabetes from the ancient period to the present day; the definition of the various types of diabetes, and the role of glucose and insulin; diagnosis and treatment, with an emphasis on prevention for those at risk; the cultural impact of the disease - on individuals, on families, and on the economy; and, the state of current research on new forms of insulin, blood glucose meters, transplants, and weight control.The volume includes a glossary of important terms and a bibliography of accessible works that discuss the disease.

Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency

Narrative Based Health Care: Sharing Stories recounts the experiences of a group of patients undergoing treatment for diabetes, may of whom are poor, socially isolated, and unable to communicate their fears and anxieties to health professionals.

The book is a practical and highly accessible supporting tool for GPs, nurses and health professionals interest in professionals development and improving services for patients. The innovative approach employed by Narrative Based Health Care is not limited to the understanding of diabetes and will therefore be of interest to all health professionals interested in addressing the clinical and service needs for any complex health problem.

The book covers a wide range of experiences, including:
Learning about diabetes
The person with newly diagnosed diabetes
Diabetes in the family
Check-ups and visits to the doctor
Medication
Supporting positive lifestyle choices
Loneliness and lack of support
Communicating across cultures
Educating and supporting other health professionals
Diabetes and women's health

The Forensic Aspects of Hypoglycaemia succinctly covers the medicolegal considerations of hypoglycaemia in a variety of scenarios including driving fatalities, petty crime, homicide and suicide. Covering the definitions and diagnosis of hypoglycaemia to its bearing on criminal behavior, this book draws on the author's extensive experience and contains a wealth of information for physicians and lawyers, including cases from the author's past and notable cases in the public domain.

While nutrition is central to the management of diabetes, there is no one "diabetic diet." Nutritional prescriptions depend on the type of diabetes, food preferences, lifestyle, treatment regimen, comorbidities, state of health, and the route of caloric administration. Nutritional Strategies for the Diabetic/Prediabetic Patient is a comprehensivereference aimed at advancing physicians' knowledge of nutrition in relation to diabetes, allowing them to provide evidence-based recommendations for their diabetic patients. It also provides dietitians and diabetic educators with an in-depth understanding of the pathophysiology and medical treatment of diabetes.

Written by scientists, clinicians, registered dietitians, and certified diabetes educators, this book reviews the molecular mechanisms of disease and drug therapy. It also provides recommendations for management with the level of evidence indicated where appropriate. In areas where little research data is available, the editors present recommendations based on extensive clinical experience. The book places particular focus on the synchronization of nutrient intake with medications, and provides unique clinical management tools, along with details of their ability to be replicated for patient use. To facilitate accessibility, it features evidence-based technical reviews of clinical literature and includes numerous tables and figures, with color photos of wound healing stages.

Addressing all aspects of nutrition in adult diabetic and prediabetic patients, Nutritional Strategies for the Diabetic/Prediabetic Patient is an important referencefor those concerned with the dietary management of this disease.

Numerous research programs have developed over the last decade to improve the understanding of the causes, prevention and treatment of diabetes and its complications. Efficient synthesis of the data and information from these diverse sources is crucial to prioritize interventions and assemble resources for the implementation of public health programs. This book meets this need and builds on previous works to reflect the evolution of science related to diabetes public health. Through compelling evidence related to the current health and economic impact of diabetes, the book provides effective approaches to prevent and manage diabetes through the practice of public health. It combines state-of-the-art descriptions of risk factors and complications, effective and cost-effective approaches to prevention and treatment, translational research, and genomics to give a comprehensive and up-to-date analysis on diabetes public health. Critical review and synthesis of influential epidemiologic studies and consensus statements, expected future advances in trials and technologies, and public health information resources are also highlighted topics. With significant attention to diabetes control in the U.S. and North America, Diabetes Public Health should be required reading for public health practitioners and researchers, as well as anyone involved in health policy, administration and management. It will also be of interest to academics in the field of diabetes and other chronic diseases.

Diabetes education is a process, the key to which is establishing a therapeutic relationship with the individual. The overall goal of diabetes education is to enhance the individual s health capability, including their ability to solve problems and apply the learning to self-care. Thus, diabetes education is an interactive process of teaching and learning where information is co-generated. This innovative and thought-provoking new book explores the how of diabetes education, rather than the what and the why . Diabetes Education: Art, Science and Evidence helps healthcare practitioners teach diabetes effectively from diagnosis onwards and ensure people living with diabetes receive individualised support and information. It enables practitioners and educators to examine and reflect on their practice when managing the person with diabetes. Bringing together all the thinking and experience of the diabetes journey in one text, this book is essential reading for all practitioners and students involved in diabetes care. SPECIAL FEATURES: * Features short stories, case studies, illustrative quotes, practice points and reflection points throughout * Edited by an internationally renowned expert in the field * Contributions from some of the world s leading diabetes educators This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from iTunes, Google Play or the MedHand Store.

Mention diabetes and what are the first things that leap to mind? Sugar levels, gluclose monitoring, and insulin? According to leading diabetes specialist Dr. Stevan Joyal, to truly combat the diabetes epidemic--both preventing it and improving the quality of life for those who have it--we must start smaller, by focusing on the microscopic yet most critical factors that control your genes and your cells. In WHAT YOUR DOCTOR MAY NOT TELL YOU ABOUT DIABETES, Dr. Joyal tells readers how to prevent and treat type 2 diabetes and reverse prediabetes (a condition affecting half of all Americans), by positively influencing the genes and cells in the body that cause the condition--all without the use of special gadgets, or crazy fad diets. In this groundbreaking, integrative treatment plan, you will find:
-the testing procedures that EVERYONE should have to discover their diabetes and prediabetes risk level
-tools to prevent and significantly control minor to serious diabetic complications
-important guidelines on diet, including especially effective "superfoods"
-an individualized, scientifically-proven natural supplement regime
-a manageable and effective exercise program
-lifestyle changes, including stress reduction tips, that can really make a difference
-recommendations on pharmaceuticals when necessary

Historically, clinical decisions in renal medicine have been challenged by the scarce availability of robust supportive evidence. Not only are the number of randomized controlled trials (RCTs) in Nephrology the third lowest amongst the medical specialties but in many instances the trials themselves are of poor quality. In addition, practice has been further influenced by extrapolation from the outcomes of general population clinical trials which exclude renal patients. The difference between the ideal trial participant and real complex cases encountered in daily practice is well recognized and further compounded in renal patients with complex pathophysiology - this ultimately makes decision making in this subset of patients a real challenge. Recently, there has been a growing interest in conducting well designed RCTs in different areas of renal medicine. However, though clinical guidelines are helpful in providing the clinicians with a frame of best available evidence for a clinical condition, it denies the unique nature of each individual patient. This book offers a thorough and critical appraisal and evaluation of the key published clinical trials that have shaped current practice in nephrology, dialysis and transplantation. It will help the practicing physician close the gap between the inflexible and generalized nature of clinical guidelines and the day-to-day clinical decision-making for individual patients. It will provide the clinician with the tools required to investigate and extract the appropriate guidance to apply to individual cases in daily practice. Moreover, it will help improve the ability of junior colleagues to appraise available evidence in a systematic way when there is lack of local guidelines or when the guidelines are difficult to apply due to logistic constraints or barriers. Lastly, this book will serve as a reference for key clinical trials in different areas of renal medicine together with literature and authors views of these trials and their impact on changing practice.​ 

The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin secretion are fundamental to the pathogenesis and progression of obesity-associated type 2 diabetes. There is a need to explain how new drugs can counter insulin resistance and insulin deficiency to a broad range of professionals, from clinical scientists active in early (and later) phase drug development to specialist physicians and increasingly primary care doctors who must tailor drug regimens to the individual patient. Clinical research methods for measuring insulin action and insulin secretion have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. The purpose of the book is to aid the selection of the most appropriate techniques for assessing insulin action, insulin secretion and body composition in humans (with particular reference to new drugs) in phase 1 and 2 studies and aid the understanding of drug effects and non-drug treatment strategies on key biochemical-hormonal defects of obesity and type 2 diabetes. The book will assume a working knowledge of human physiology relating to glucose metabolism and will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties.

A Harvard Medical School diabetes specialist and a top exercise physiologist share a proven and effective 12-week plan to reverse the course of Type 2 diabetes, lose weight, and ditch the medication for good. In this groundbreaking book, diabetes and weight management expert Osama Hamdy, M.D., Ph.D., reveals how you can reverse the course of your type 2 diabetes, lose weight for good and finally reclaim your health-in just 12 weeks! This book will help you: * Cut your medications by 50-60%-or even stop them altogether! * Learn how to safely lose-and keep off-those 10, 20 or even 50 plus pounds that are holding you back from a healthy life. * Tailor your exercise plan to the way you really live and work, so you can get results without being a slave to the gym. * ...and more! With information on how to create checklists, goal worksheets, and including real-life success stories, The Diabetes Breakthrough will help keep you motivated in making smart decisions-even on the busiest days!

The increasing prevalence of morbid obesity has led the World Health Organization to coin the descriptive term "globesity" to reflect the worldwide nature of the problem. Providing health care to these patients, especially when surgery is required, can be extremely challenging owing to the specific needs in respect of logistics, facilities, and professional expertise. Appropriate care has to date often been unachievable and unaffordable outside of established bariatric centers, but such centers themselves usually have insufficient capacity and resources to cope with the demand among the general population. This book therefore provides a wealth of guidance and helpful tips and tricks on how to deal with obese patients within a general surgery setting. Importantly, it highlights the need for global rethinking on public health as regards resource allocation and patterns and standards of care, with the ultimate goal of improving outcomes through greater affordability.

Studies on Diabetes examines how increased oxidative and nitrosative stress - one of the leading causes of diabetes complications - pathologically affects multiple tissues in the body. The volume editors and chapter authors are leading investigators in the field of basic and clinical research in diabetes and vascular disease. Their contributions represent a wealth of knowledge on and research into how diabetes triggers metabolic abnormalities that lead to hyperactivation of cellular and mitochondrial pathways that ultimately result in oxidative and nitrosative stress that left un-neutralized, results in tissue damage. Each chapter provides the reader with invaluable insight to the complicated mechanisms responsible for diabetes complications and vascular disease. Potential treatments for diabetes complications from animal models to the patient will also be discussed. This is essential reading for researchers and clinicians in endocrinology, diabetes, vascular disease and oxidative stress.

This book outlines risk assessments for 28 diseases and medical conditions including the following aspects: genetics, biochemistry, serology, past medical history, family history, co-morbidities, age, gender, ethnicity, nutrition and lifestyle. Recommendations are made for how to avoid, eliminate or mitigate risks. Preventing measures concerning chemical compound intake, lifestyle and nutrition are proposed. The unique content and approach of the book to chronic disease management make it a state-of-the-art reference work, addressing a missing component of medical care and reflecting the cutting edge of preventive medicine.

Diabetes and Kidney Disease reviews the most up-to-date research on diabetic nephropathy, the current understanding of its pathophysiology, renal structural alterations and clinical features and summarizes recent evidence-based clinical treatment modalities for the prevention and management of diabetic kidney disease. General clinical aspects are covered, as well as an overview to the novel approaches being designed by leading researchers in the field. A convenient compendium for physicians involved in the care of diabetic patients with varying degrees of kidney involvement, Diabetes and Kidney Disease is also a handy resource for medical residents and students interested in the current status and future approaches to reducing the burden of diabetes and diabetic kidney disease.

A comprehensive guide to help you understand why we put on weight! Dr Dawn explains our dietary needs at different stages of life, how metabolism differs, and the implications for our general health and wellbeing. There is a sensible look at the role of diet and exercise. Dr Dawn describes how even modest weight loss can affect your risk of developing other illnesses such as heart disease, and even how long you can expect to live. There is a comprehensive chapter on diabetes, including the types of diabetes and what we mean by terms like insulin resistance and metabolic syndrome.

This concise handbook provides an overview of incretin-based therapies and guidance for incorporating them into the treatment of type 2 diabetes. Chapters include landmark clinical trials and international treatment guidelines in order to update readers with all major advances in the field. An ideal resource for medical professionals that treat patients with type 2 diabetes in hospital and clinical settings.

This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies. Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique. This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.

The demands of caring for a child with diabetes can often become exhausting and overwhelming. Diabetes Distress and Burnout for Parents and Carers provides support to those caring for a child with type 1 diabetes. This booklet helps readers to identify the symptoms of burnout, understand what triggers them, and learn what steps they can take to improve their symptoms and build resilience. Featuring quotes from caregivers who have experienced and overcome burnout and practical tools to manage and ease the symptoms alongside guidance on what to do if a relapse occurs. In addition, the booklet highlights the support available and provides helpful links to sources and organisations where readers can go for further information on diabetes. An ideal resource for caregivers of children and young people with type 1 diabetes, as well as the wider diabetes healthcare team, including clinical psychologists, specialist nurses, endocrinologists and general practitioners.

This contributed volume presents computational models of diabetes that quantify the dynamic interrelationships among key physiological variables implicated in the underlying physiology under a variety of metabolic and behavioral conditions. These variables comprise for example blood glucose concentration and various hormones such as insulin, glucagon, epinephrine, norepinephrine as well as cortisol. The presented models provide a powerful diagnostic tool but may also enable treatment via long-term glucose regulation in diabetics through closed-look model-reference control using frequent insulin infusions, which are administered by implanted programmable micro-pumps. This research volume aims at presenting state-of-the-art research on this subject and demonstrating the potential applications of modeling to the diagnosis and treatment of diabetes. The target audience primarily comprises research and experts in the field but the book may also be beneficial for graduate students.

In modern medicine, the aging population is prone to many simultaneous cardiovascular (CV) risk factors which often produce co-incident pathology. Nowhere is this more obvious than in the interaction between Chronic Kidney Disease (CKD), Diabetes and diverse CV diseases (CVD). This is a complex and challenging area, as the presence of CKD/diabetes promotes CVD while also complicating its treatment. The emergence of CKD as a public health priority is one of the most challenging problems of modern medicine. It is now solidly established that renal dysfunction portends a high risk for cardiovascular disease. Cardiovascular diseases remains the main cause of death in western societies and the amplification of the death risk conveyed by coexisting CKD, even though still poorly understood, appears considerable. The bidirectional link that associates renal and cardiovascular diseases, the high risk of the death signalled by their coexistence and the considerable epidemiological burden imposed by this link is at the basis of the emergence of a new discipline aiming at making the borders between nephrology and cardiovascular medicine even more permeable than before. The term Cardio-Renal Syndrome was coined around 5 years ago to try to formalize this link, and act as a stimulus to interaction between clinical teams, researchers and others to achieve better management and outcomes for all. This book takes clinical presentations and clinical problems as its base, and then discuss the evidence for best management of common clinical problems as well as the reasons for the complex interplay between the cardiac and renal systems. Moreover, it addresses the issue of organizing healthcare to maximize the opportunities for prevention and best healthcare economic returns, building on cutting edge initiatives at the Karolinska, Stockholm. The book will be of immediate value and interest to all cardiologists and renal physicians.

This handbook is an overview of the diagnosis, treatment and long-term management of diabetic retinopathy, within the context of overall long-term diabetes disease management. Diabetes-related eye damage (diabetic retinopathy) is one of the most common complications of diabetes, affecting approximately 30-40% of people with diabetes. The situation is so severe that in countries such as the US and UK, diabetic retinopathy is currently the leading cause of blindness in people age 20 to 74 years old. Fortunately, there are several existing and emerging treatments on the horizon and with adequate control of the underlying diabetes, this condition can be successfully managed.

Over the last twenty years, type 2 diabetes skyrocketed to the forefront of global public health concern. In this book, Mari Armstrong-Hough examines the rise and response to the disease in two societies: the United States and Japan. Both societies have faced rising rates of diabetes, but their social and biomedical responses to its ascendance have diverged. To explain the emergence of distinctive strategies to explain and manage diabetes, Armstrong-Hough argues that physicians act on not only increasingly globalized professional standards but also on local knowledge, explanatory models, and cultural toolkits. As a result, strategies for clinical management diverge sharply from one country to another. Armstrong-Hough demonstrates how distinctive practices endure in the midst of intensifying biomedicalization, both on the part of patients and on the part of physicians, and how these differences grow from broader cultural narratives about diabetes in each setting.

This book is intended to provide up-to-date and emerging information in the field of diabetes mellitus with a focus on preventive, predictive and personalized medicine.

Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.