This book presents essential information on biomechanical features of the diabetic foot, which could help to minimize the risk of future diabetic foot problems. India has recently been classified as the 'diabetic capital' of the world. Type 2 diabetes mellitus has become a serious concern for Indian society, where the prevalence rate is increasing exponentially. Similarly, the comorbidities and foot complications of type 2 diabetes mellitus are worsening day by day. Of all complications, diabetes peripheral neuropathy is the most common, and leads to foot deformities, pain, altered sensation, loss of foot arch, etc. The ultimate fate can even be gangrene and amputation. Accordingly, foot complications of diabetes represent a pressing medical issue. Sharing insights into diabetic foot syndrome, its causative factors, prevention and management, this book offers a valuable resource for medical and paramedical students, researchers, podiatrists, surgeons, and physicians alike.

When you have diabetes yourself or in your family, you must become your own expert. Equipped with the knowledge, strategies and tips provided in this easy-to-read resource, you will be fully prepared to take the best care of yourself and your diabetes. With over 40 chapters looking at topics ranging from nutrition, pregnancy and travel, to associated conditions, research and new developments, this book digs deep into the practicalities of managing and living with diabetes. This latest edition also contains advice on how to use the new hybrid insulin pump. OTHER KEY FEATURES INCLUDE: Glossary with over 150 medical terms Over 400 illustrations Over 1,000 journal and article references, plus website recommendations for further reading Details of self-help and support organisations, as well as real-life stories from people with diabetes. Medical research has conclusively proved that looking after your diabetes is key to avoiding pitfalls and long-term risks. By understanding your diabetes, you can live a full, healthy and happy life.

Diabetes: Epidemiology, Pathophysiology and Clinical Management aims to be the one-stop diabetes book for researchers, scientists and clinicians. It details the epidemiology, causes, molecular mechanisms, molecular markers, available drugs, experimental drugs, treatment modalities, and dietary and lifestyle approaches related to diabetes. It focuses on various molecular aspects of diabetes, and its related co-morbidities. Apart from the drug-based treatment approach based on international guidelines, this book also describes various surgical treatments available for cases of uncontrolled symptomatic diabetes. It also lays emphasis on the future possibilities of different approaches for diabetes management. Key Features Includes treatment guidelines and approaches to diabetes provided by major global diabetes associations Provides a thorough and comprehensive assimilation of detailed information and updates in the field of diabetes, helpful for researchers, scientists and clinicians Contains a chapter on anti-diabetic drugs, that covers both the commercially approved drugs as well as those that are in various phases of experimental, pre-clinical, and clinical trials

Prevention and treatment of cardiometabolic disorders by lifestyle management is the most understood and effective applications of this emerging field. The focus of this book on prediabetes, diabetes and cardiometabolic diseases is timely and will be a welcome addition to clinicians who wish to gain more knowledge and competence in the area. This book will focus on the metabolic syndrome, which is the largest non-communicable disease of our time, and lifestyle approaches that drastically reduce the risks and adverse effects of this condition. Presents a detailed review of clinical evidence and guide for implementation. Provides a toolkit to counter both the high cost of medications and the need to address metabolic disorders associated with insulin resistance early, before or simultaneous to when medications are indicated.

The Carbs & Cals Flashcards are a visual guide to counting carbs, calories and other nutrients in a range of popular food and drinks. Each of the 64 large, durable cards displays a food photo and portion weight. The reverse of the card shows the same photo with its nutritional information. NEW FEATURE for this edition: The amount of carbs are also displayed as blood glucose icons, to visually show the possible effect of each portion on blood glucose levels. Carbs & Cals Flashcards are perfect for diabetes, weight loss and portion control, and can be used in a variety of ways at home or in a clinical setting. Use alongside the Carbs & Cals PACK 1 and WORLD FOODS flashcard sets, to make a bumper pack of 192 unique flashcards!

This book is the first of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. HDL comprises a diverse group of lipoproteins and its composition and metabolism are dynamic. In this volume, the focus is on the changes observed in HDL under different health statuses, with particular attention to the functional and structural correlations of HDL and apolipoprotein A-1. The impacts of a wide variety of factors on HDL are examined in depth, covering, for example, diet, exercise, smoking, age, diverse diseases, and different forms of environmental pollution. It has long been known that HDL has anti-atherosclerotic and antidiabetic properties, and more recently its anti-aging activities have been recognized. These benefits of HDL are highly dependent on its lipids, proteins, apolipoproteins, and enzymes, and specifically their composition and ratios. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.

Diabetes and Fundus OCT brings together a stellar cast of authors who review the computer-aided diagnostic (CAD) systems developed to diagnose non-proliferative diabetic retinopathy in an automated fashion using Fundus and OCTA images. Academic researchers, bioengineers, new investigators and students interested in diabetes and retinopathy need an authoritative reference to bring this multidisciplinary field together to help reduce the amount of time spent on source-searching and instead focus on actual research and the clinical application. This reference depicts the current clinical understanding of diabetic retinopathy, along with the many scientific advances in understanding this condition. As the role of optical coherence tomography (OCT) in the assessment and management of diabetic retinopathy has become significant in understanding the vireo retinal relationships and the internal architecture of the retina, this information is more critical than ever.

This book is the second of two volumes that offer a comprehensive, up-to-date account of current knowledge regarding high-density lipoprotein (HDL), the changes that occur in HDL under different conditions, the clinical applications of HDL, and means of enhancing HDL functionality. In this volume, the focus is on the improvement of HDL, enhancement of its functionality, and the use of HDL for therapeutic purposes. In the first section, up-to-date information is provided on such topics as the tumor regression-promoting and antidiabetic activities of reconstituted HDL containing V156K apolipoprotein A-I, the enhancement of HDL effects by high doses of vitamin C, the benefits derived from incorporation of growth hormones 1 and 2 into rHDL, and the biological functions of omega-3 linolenic acid in rHDL. The enhancement of HDL functionality by policosanol and the resultant benefits are thoroughly examined in a separate section. Readers will also find the latest information on clinical applications of HDL. Here, specific topics include the enhancement of adenoviral gene delivery and the delivery of rapamycin. In documenting the latest knowledge in this field, this volume will be of interest to both researchers and clinicians.

The thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country's prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant.

Captures the art and science of diabetes self-management education Serves to help educators support their patients in their diabetes self-care efforts Focuses on diabetes self-care with education as the major component Diabetes affects an estimated 20 million people in the United States, with many people remaining unaware that they suffer from the disease. While the number of diabetics continues to rise, the number of caregivers who specialize in diabetes treatment does not. In Educating Your Patient with Diabetes, Katie Weinger and Catherine Carver assemble commentary from a panel of leading diabetes practitioners and researchers and put together a highly readable guide to supplying patients with diabetes with the information and ability to successfully cope with their disease. The authors and editors provide substantive data on successful models of diabetes education and the process of educating diabetes sufferers. Additional chapters discuss diabetes in pregnancy, the challenge of weight and diabetes management in clinical practice, and diabetes education in geriatric populations. Timely and accessible, Educating Your Patient with Diabetes is a must have for all diabetes educators, physician assistants, nurses, and endocrinologists who endeavor to support their patients' diabetes self-care efforts and help them maximize the opportunities for patient learning.

Cardiovascular Endocrinology and Metabolism: Theory and Practice of Cardiometabolic Medicine discusses the close intersection between metabolic disorders and cardiovascular disease, covering the basic science and pathophysiology of disease and the latest research in pharmacological approaches and translational therapeutic options. This book is a valuable resource for the vascular and endocrinology clinical and research communities in need of knowledge and potential outcomes. The global increase in the prevalence of cardiometabolic disorders, and the introduction of therapeutic options for treating metabolic disease that also lower cardiovascular risk, is bringing endocrinologists and cardiologists together in a shared clinical experience.

The book provides an informative overview of diabetes mellitus in conjunction with current plant-based treatments for this disease and available methods for studying the antidiabetic activities of scientifically developed plant products, mechanisms of action, their therapeutic superiority, and current genome editing research perspectives and biotechnological approaches. The book begins with an introduction to diabetes, giving an overview of the history, diagnosis, classification, pathophysiology, and risk factors. It goes on to review traditional uses of plants for diabetes along with some ethnobotanical information as well. The results of scientific studies on the various modes of action of antidiabetic plants are discussed, such as the molecular aspects active plant-based antidiabetic drug molecules. A section featuring recent biotechnological advancements of antidiabetic plants and plant-based antidiabetic drugs covers advances in molecular breeding and application of molecular markers, biotechnologically engineered transgenic medicinal plants, and advances in genomic editing tools and techniques. This volume will be helpful for researchers, medical practitioners, academicians, students in the study of plant-based treatments for the treatment of diabetes mellitus.

Noncommunicable Diseases: A Compendium introduces readers to noncommunicable diseases (NCDs) - what they are, their burden, their determinants and how they can be prevented and controlled. Focusing on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world's biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs; (ii) the burden, epidemiology and priority interventions for individual NCDs; (iii) social determinants and risk factors for NCDs and priority interventions; (iv) global policy; (v) cross-cutting issues; and (vi) stakeholder action. Drawing on the expertise of a large and diverse team of internationally renowned policy and academic experts, the book describes the key epidemiologic features of NCDs and evidence-based interventions in a concise manner that will be useful for policymakers across all parts of society, as well as for public health and clinical practitioners.

This book covers a wide range of topics concerning human tear based science, starting from basics such as the normal composition of tears and moving up to novel disease detection platforms. The entire approach is pioneering, as tears are beginning to be recognized as the most invaluable non-invasive tool in diagnostics. Interestingly, the concept is not restricted to ocular diseases: In recent years, tear diagnostics is increasingly being tapped even for cancer detection. Hopefully, non-invasive tear diagnostics will eventually replace today's invasive disease detection and monitoring techniques. Previous literature on tear diagnostics has been restricted to scientific journal articles, most of which dealt with a single tear constituent, such as a protein. This book offers a far more comprehensive and handy 'reference guide,' presenting both basic and advanced information and data. Accordingly, it will be useful for researchers in academia and the pharmaceutical industry, as well as healthcare professionals and diagnostic kit developers.

Features * The first collective book combining accumulated knowledge and experience in the field of diabetes research using biophotonics. * Contributions from leading experts in the field. * Combines the theoretical base of the described methods and approaches, as well as providing valuable practical guidance and the latest research from experimental studies.

The book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.

Apart from diet and exercise, the strategic use of different classes of prescribed or non-prescribed xenobiotic compounds for the restoration of euglycemic levels in the body is well known. The ongoing rivalry between the recommended usage of allopathic medicines versus ayurvedic remedies has encouraged many researchers to focus their studies on thoroughly isolating and characterizing the extracts from different parts of plants and then evaluating their relative activities via in vitro, in vivo and in some cases clinical studies. Alternative Medicines for Diabetes Management: Advances in Pharmacognosy and Medicinal Chemistry provides a holistic view of all oral therapies for diabetes mellitus that are available to the public by removing the silos and stigmas that are associated with both allopathic and ayurvedic medicines. Additional Features Include: Highlights the potential role of dietary and medicinal plant materials in the prevention, treatment, and control of diabetes and its complications. Educates readers on the benefits and shortcomings of the various present and potential oral therapies for diabetes mellitus. Allows quick identification and retrieval of material by researchers learning the efficacy, associated dosage and toxicity of each of the classes of compounds. Presents the history, nomenclature, mechanisms of action and shortcomings for each of the various sub-classes of allopathic therapeutants for diabetes mellitus and then introduces ayurvedic medicines. Section C discusses various metallopharmaceuticals and provides a holistic view of all available and potential therapies for the disease.

Chronic Hope is a long drink of cool water for the parent thirsting for practical wisdom in navigating the emotional stress of raising their chronically ill child. Leaning on Bonnie O'Neil's personal experience as a caregiver Chronic Hope delivers practical insight and solutions while avoiding the tone of a typical self-help book. Instead, it reads like a conversation with a friend, where one parent's stories give the other parent permission to feel the full range of their emotions and encourages them to discover hope in the long journey. Readers witness Bonnie's mistakes and missteps, glean from her revelations, and find inspiration in the principles and attitudes she begins to apply to everyday situations. Through story and reflection, Bonnie gently shares a vision of navigating chronic disease with strength, resilience and loving self-sacrifice. Chronic Hope leverages one family's journey raising a child with chronic illness and provides readers the tools necessary to process their own emotional responses to the unexpected path ahead of them. Thematically, Chronic Hope begins deep within the heart of the caregiver and gradually works itself outward into each relationship within the family, and eventually into the wider world. Chronic Hope offers a fresh vision of hope in the darkest valleys of illness, suffering, and broken dreams.

This book covers the medical condition of diabetic patients, their early symptoms and methods conventionally used for diagnosing and monitoring diabetes. It describes various techniques and technologies used for diabetes detection. The content is built upon moving from regressive technology (invasive) and adapting new-age pain-free technologies (non-invasive), machine learning and artificial intelligence for diabetes monitoring and management. This book details all the popular technologies used in the health care and medical fields for diabetic patients. An entire chapter is dedicated to how the future of this field will be shaping up and the challenges remaining to be conquered. Finally, it shows artificial intelligence and predictions, which can be beneficial for the early detection, dose monitoring and surveillance for patients suffering from diabetes

Diabetes Digital Health and Telehealth explains, from technologic, economic and sociologic standpoints how digital health and telehealth have come to dominate the management of diabetes. The book also includes information on improved telemedicine tools and platforms for communicating with patients, reviewing medical records, and interpreting data from wearable devices. In addition, evolving wearable sensors such as continuous glucose monitors, closed loop automated insulin delivery systems, cuffless blood pressure monitors, exercise monitors and smart insulin pens are covered.

Painful diabetic polyneuropathy is the most common and disturbing of painful conditions experienced by people with diabetes. As the diabetes rate continues to grow, the number of people suffering from painful diabetic polyneuropathy will as well - increasing both patient suffering and demands on healthcare resources. Painful Diabetic Polyneuropathy covers all aspects of these painful disorders from pathophysiology and diagnosis, treatment and prevention, future approaches and the nursing perspective, to billing issues and the patient's experience. Written by experts in their fields, each chapter presents the full perspective of these painful disorders with an emphasis on evidence-based scientific information. Painful Diabetic Polyneuropathy is a comprehensive resource for general and family medicine practitioners, neurologists and pain medicine specialists. It will also serve as a resource for patients for education, support, and treatment sites.

Few diabetes books focus specifically on the day-to-day issues facing people who use insulin. Diabetes educator Gary Scheiner provides the tools to 'think like a pancreas' -- to successfully master the art and science of matching insulin to the body's ever-changing needs. Comprehensive, free of medical jargon, and packed with useful information not readily available elsewhere, such as: day-to-day blood glucose control and monitoring designing an insulin program to best match your lifestyleup-to date medication and technologynew insulin formulations and combinationsand moreWith detailed information on new medications and technologies -- both apps and devices -- surrounding insulin, as well as new injection devices, and dietary recommendations, Think Like a Pancreas is the insulin users go-to guide.

Diabetic Neuropathy identifies the most accurate early biomarkers of nerve damage to better understand pathophysiology and diagnose diabetic neuropathy in the clinical care of patients, and in particular, permit an accurate evaluation of future therapies in clinical trials. This succinct reference focuses on the current data and research on diabetic neuropathy and is essential reading for researchers in endocrinology, neurology and pharmacology, along with clinicians that need to better understand the novel pathogenetic pathways leading to diabetic neuropathy and the treatments.