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Books > Medicine > Clinical & internal medicine > Endocrinology > Diabetes
Noncommunicable Diseases: A Compendium introduces readers to noncommunicable diseases (NCDs) - what they are, their burden, their determinants and how they can be prevented and controlled. Focusing on cardiovascular disease, diabetes, cancer and chronic respiratory disease and their five shared main risk factors (tobacco use, harmful use of alcohol, unhealthy diet, physical inactivity and air pollution) as defined by the United Nations, this book provides a synopsis of one of the world's biggest challenges of the 21st century. NCDs prematurely claim the lives of millions of people across the world every year, with untold suffering to hundreds of millions more, trapping many people in poverty and curtailing economic growth and sustainable development. While resources between and within countries largely differ, the key principles of surveillance, prevention and management apply to all countries, as does the need to focus resources on the most cost-effective and affordable interventions and the need for strong political will, sufficient resources, and sustained and broad partnerships. This compendium consists of 59 short and accessible chapters in six sections: (i) describing and measuring the burden and impact of NCDs; (ii) the burden, epidemiology and priority interventions for individual NCDs; (iii) social determinants and risk factors for NCDs and priority interventions; (iv) global policy; (v) cross-cutting issues; and (vi) stakeholder action. Drawing on the expertise of a large and diverse team of internationally renowned policy and academic experts, the book describes the key epidemiologic features of NCDs and evidence-based interventions in a concise manner that will be useful for policymakers across all parts of society, as well as for public health and clinical practitioners.
This Handbook fulfils a pressing need within the area of
psychological measurement in diabetes research and practice by
providing access to material which has either been widely dispersed
through the psychological and medical literature or has not
previously been published.
Diabetes and the Kidney provides endocrinologists and nephrologists of all levels with expert clinical diagnosis and management guidance for this extremely common diabetic complication. Practical and accessible, chapters contain text features such as case histories, potential pitfall boxes, key points, management algorithms, and useful weblinks to fully engage the reader and provide expert guidance to help clinicians best manage their patients. In addition, all relevant international society guidelines and recommendations are fully included. After an initial analysis of the epidemiology and pathogenesis of kidney complications in diabetes, it quickly moves on to the following core sections: - Special Situations, Risk factors and Complications - examining diabetic nephropathy in relation to each other diabetic complication, ie cardiovascular disease- Prevention and Therapy - focusing on the most up to date information regarding prevention, diagnosis, treatment, and management of kidney disease in diabetes. Expertly edited, and with contributions from an experienced international team, Diabetes and Kidney Disease will be the perfect tool to consult when managing diabetic patients with associated kidney problems.
Lose weight while enjoying delicious meals with these 125 insulin resistant recipes and meal plans to improve your health and lower your risk for type 2 diabetes. Many people struggle with their weight, trying every new diet and health trend but still are unable to keep the weight off or lose unwanted belly fat. The problem may not be lack of willpower, but insulin resistance. When insulin can't do its job of removing sugar from the blood, that sugar is turned to fat, causing weight gain and increasing the risk of type 2 diabetes. But this damage can be reversed simply by changing your diet and activity level. In The Everything Guide to the Insulin Resistance Diet, you will learn how to choose healthy foods like fruits, vegetables, whole grains, fish, and lean poultry, while limiting the amount of unhealthy fat, sugar, meats, and processed starches. Now you can make the lifestyle changes you need to lose weight and improve your health with this valuable resource that includes 125 recipes and a 10-week plan for healthy eating and increased activity. With this guidebook you can have the body-and health-of your dreams, all while eating the delicious food you love!
The cause of diabetes mellitus is metabolic in origin. However, its major clinical manifestations, which result in most of the morbidity and mortality, are a result of its vascular pathology. In fact, the American Heart Association has recently stated that, "from the point of view of cardiovascular medicine, it may be appropriate to say, diabetes is a cardiovascular disease" (1). But diabetic vascular disease is not limited to just the macrovasculature. Diabetes mellitus also affects the microcirculation with devastating results, including nephropathy, neuropathy, and retinopathy. Diabetic nephropathy is the leading cause of end-stage renal disease in the United States, while diabetic retinopathy is the leading cause of new-onset blindness in working-age Americans. The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. Over 10 million Americans have been diagnosed with diabetes mellitus, while another 5 million remain undiagnosed. The impact from a public health perspective is huge and increasing. As the population of the United States grows older, more sedentary, and obese, the risk of developing diabetes and its complications will increase. Epidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease. Over 65% of patients with diabetes mellitus die from a cardiovascular cause. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.
A comprehensive guide to help you understand why we put on weight! Dr Dawn explains our dietary needs at different stages of life, how metabolism differs, and the implications for our general health and wellbeing. There is a sensible look at the role of diet and exercise. Dr Dawn describes how even modest weight loss can affect your risk of developing other illnesses such as heart disease, and even how long you can expect to live. There is a comprehensive chapter on diabetes, including the types of diabetes and what we mean by terms like insulin resistance and metabolic syndrome.
Diabetes has long been recognized as a disease of high blood sugar, and there has been a continuous search of the exact reason for its development and effective treatment. In 2005, the World Health Organization had estimated that more than 180 million people worldwide suffer from diabetes mellitus and indicated that this figure is likely to double within the next 20 years. Among the 3.8 million deaths each year associated with diabetes, about two thirds are attributable to cardiovascular complications, and diabetes is now considered to be a major metabolic risk factor for the occurrence of heart disease. "Diabetic Cardiomyopathy: Biochemical and Molecular Mechanisms" is a compilation of review articles devoted to the study on the topic with respect to biochemical and molecular mechanisms of hyperglycaemia. The wide range of areas covered here is of interest to basic research scientists, clinicians and graduate students, who are devoted to study the pathogenesis of diabetes-induced cardiovascular dysfunction. Furthermore, some chapters are directed towards increasing our understanding of novel ways for the prevention/treatment of cardiomyopathy. Twenty five articles in this book are organized in three sections. The first section discusses general aspects of the metabolic derangements in diabetic cardiomyopathy including metabolic alterations and substrate utilization as well as cardiac remodelling in the heart; role of diet in the development of metabolic syndrome in the heart; effect of hyperglycaemia in terms of biochemical and structural alterations in heart. In the second section, several cellular and molecular mechanisms are discussed indicating that diabetic cardiomyopathy is a multifactorial and complex problem. The third section discusses the prevention and treatment of diabetes using appropriate diet, proper supplements including antioxidants, angiotensin inhibitors and some other drugs. All in all, this book discusses the diverse mechanisms of diabetic cardiomyopathy with some information on new therapeutic approaches for finding solutions to prevent or reverse the development of cardiac dysfunction.
Even a brief scan of the table of contents of the present volume is enough to disclose the diversity of research interests and opinions in the field of lipidology. It is precisely this diversity that is the strength of our field and that was showcased by the XII International Symposium of DRUGS AFFECTING LIPID METABOLISM (DALM). The papers published here from these proceedings may be divided into three categories: those that define-and refine---our understanding ofthe clinical benefit of aggressive lipid management, those that develop our knowledge of ris!. assessment, and those that discuss the genetic, bio~hemical, and biophysical mechanisms underlying the pathology of coronary heart disease. On the clinical front, further analysis of the results of the Scandinavian Simvastatin Survival Study (4S) has indicated the cost-effectiveness of therapy in patients with established coronary heart disease. The West of Scotland Coronary Prevention Study (WOSCOPS), whose methodology was described at the DALM XII symposium, has demonstrated in a mostly primary-prevention population what 4S demonstrated for secondary prevention the year before: aggressive lipid-regulating therapy reduces coronary heart disease morbidity and mortality rates without concurrently increasing mortality from noncardiovascular causes. In the future, important considerations will be to develop protocols that maximize benefit in groups underrepresented in traditional clinical research for example, women and the elderly-and to improve compliance to existing treatment regimens. Furthermore, antioxidant, omega-3 fatty acid, and gene therapies warrant further investigation.
Key Features * Details the latest diagnostic tests and treatments of diabetes and its complications, useful for ready reference by students, physicians, and healthcare professionals. * Explains how heart failure and stroke are deadly complications of diabetes along with kidney failure and life-threatening infections. * Establishes how cancer is linked to diabetes - a fact many people are not aware of - the book details the 6 types of cancer that may result from the disease, along with an individualized focus on the different "areas" of complications that occur from diabetes. * Discusses the effect of diabetes upon the minds of patients, in relation to depression, anxiety, panic, PTSD, eating disorders, delirium, and dementia.
Studies on Diabetes examines how increased oxidative and nitrosative stress - one of the leading causes of diabetes complications - pathologically affects multiple tissues in the body. The volume editors and chapter authors are leading investigators in the field of basic and clinical research in diabetes and vascular disease. Their contributions represent a wealth of knowledge on and research into how diabetes triggers metabolic abnormalities that lead to hyperactivation of cellular and mitochondrial pathways that ultimately result in oxidative and nitrosative stress that left un-neutralized, results in tissue damage. Each chapter provides the reader with invaluable insight to the complicated mechanisms responsible for diabetes complications and vascular disease. Potential treatments for diabetes complications from animal models to the patient will also be discussed. This is essential reading for researchers and clinicians in endocrinology, diabetes, vascular disease and oxidative stress.
Key Features Explains normal physiology of pregnancy in addition to the physiology, evaluation, and management of endocrine diseases in pregnancy, and in the pre- and post-partum periods. Explores from a clinical standpoint with practical applications, useful for students, residents, fellows, mid-level providers, and practicing physicians. Discusses special considerations and emerging topics including pregnancy in transgender men, obesity and metabolism, and endocrine emergencies.
The follow-up to The Sunday Times bestseller The Diabetes Weight-loss Cookbook Katie and Giancarlo Caldesi are back to guide you through how to reverse the progress of type 2 diabetes, lose weight and bring your blood sugar down to a normal level. This new book is full of simple, delicious recipes that encourage and help you to sustain permanent lifestyle change. The Reverse Your Diabetes Cookbook is packed full of mouthwatering low-carb dishes using easy-to-source, inexpensive ingredients. With recipes to address common pitfalls, such as food on the go and take-to-work lunches, alongside fakeaways providing healthy alternatives to takeaway favourites, this is food to fill you up without fattening you up. With a foreword by pioneering GP and diabetes specialist Dr David Unwin, this life-changing book shows you how you too can prevent and reverse type 2 diabetes by adopting a low-carb way of life and choosing lifestyle medicine over lifelong medication.
The enormous increase in our knowledge and understanding of diabetes mellitus in recent years has resulted in new management strategies for greatly enhancing care in diabetic pregnancy. Clinicians responsible for the care of women with diabetes need to keep abreast of these advances. Diabetes and Pregnancy: An International Approach to Diagnosis and Management is a comprehensive, yet practical guide to the present state of knowledge regarding diabetic pregnancy. It summarizes published literature, and offers clear and valuable information on the practicalities of providing special care before, during and after pregnancy. This volume will be indispensable to all members of the health care team involved in the care of pregnant diabetic women and their babies, including obstetricians, neonatologists, diabetes physicians, specialist nurses, midwives as well as general practitioners.
Computer-Assisted Diagnosis: Diabetes and Cardiovascular Disease brings together multifaceted information on research and clinical applications from an academic, clinical, bioengineering and bioinformatics perspective. The editors provide a stellar, diverse list of authors to explore this interesting field. Academic researchers, bioengineers, new investigators and students interested in diabetes and heart disease need an authoritative reference to reduce the amount of time spent on source-searching so they can spend more time on actual research and clinical application. This reference accomplishes this with contributions by authors from around the world.
Published on behalf of The British Dietetic Association , Advanced Nutrition and Dietetics in Diabetes is an exploration of the evidence and practice of nutrition in diabetes, offering a global view of the lifestyle interventions for the prevention and management of diabetes, including management of complications and special population groups. With internationally recognised authors, this book applies the rigour of evidence-based medicine to important enduring topics in diabetes, such as: * public health efforts at diabetes prevention * formulating nutritional guidelines for diabetes * carbohydrates and the glycaemic index * the management of diabetes in older people The authors draw on their research and practical experience to offer sound guidance on best practice, ensuring that interventions are both scientifically secure and effective. ABOUT THE SERIES Dietary recommendations need to be based on solid evidence, but where can you find this information? The British Dietetic Association and the publishers of the Manual of Dietetic Practice present an essential and authoritative reference series on the evidence base relating to advanced aspects of nutrition and diet in selected clinical specialties. Each book provides a comprehensive and critical review of key literature in its subject. Each covers established areas of understanding, current controversies and areas of future development and investigation, and is oriented around six key themes: * Disease processes, including metabolism, physiology, and genetics * Disease consequences, including morbidity, mortality, nutritional epidemiology and patient perspectives * Nutritional consequences of diseases * Nutritional assessment, drawing on anthropometric, biochemical, clinical, dietary, economic and social approaches * Clinical investigation and management * Nutritional and dietary management * Trustworthy, international in scope, and accessible, Advanced Nutrition and Dietetics is a vital resource for a range of practitioners, researchers and educators in nutrition and dietetics, including dietitians, nutritionists, doctors and specialist nurses. Please note Due to recent developments in this area, Chapter 4.3 on Nutritional management of glycaemia in type 2 diabetes has been withdrawn from the publication, and all future reprints will be replaced by a new chapter. All ebook versions are already updated. The contributor retains copyright to this chapter whilst their name still appears associated to the chapter.
The management of diabetes in children and young people continues to develop in important areas, including self-monitoring, insulin delivery, dietary prescription, concept of control and the early identification of complications. Meanwhile responsibility for care has become a partnership between patients, parents and a multi-disciplinary team of health professionals. Key features of Childhood and Adolescent Diabetes include:
Diabetes is a chronic disease involving self-management by the patients. This book teaches providers the skills to translate and transfer complex medical information to empower patients to participate in making well-informed decisions about their own care on a daily basis, as directed by the American Diabetes Association. It provides the basic knowledge around the pathophysiology of diabetes, different management options including insulin management and calculations, information on how foods affect blood sugars and how to address cardiovascular risk factors. This book aims to change clinical outcomes through its unique presentation of information and its approach to awareness. Key Features Follows a unique approach in imparting techniques that bring long-term patient behaviour changes, making the provision of chronic disease management more efficient and satisfying Serves to help professionals in their day-to-day patient management to achieve better outcomes Addresses the area of need for primary care and helps to make well-informed decisions by understanding the essential cost of care
Key features include: Details the role of plants for the treatment and management of cancer and diabetes Discusses the role of phytocompounds as ligands for cancer and diabetic targets Reviews plants and the potential of phytochemicals as antidiabetic and anticancer drugs Explores the green biosynthesis of nanoparticles and their treatment efficiency
'Two years ago I turned 50, weighed 22 stone and was heavily medicated for type 2 diabetes. I thought it would be all downhill from there. By radically changing my nutrition, cutting out sugar, and taking up exercise, I've changed my life and reversed my diabetes. I hope my story will inspire others to regain their health and happiness and discover the new lease of life I'm experiencing.' Tom Watson began to put on weight in his early twenties, having developed an appetite for fast food and cheap beer while studying at the University of Hull. As time progressed - and his penchant for anything sweet, fatty or fizzy persisted - he found himself adjusting his belt, loosening his collar and upsizing his wardrobe to XXL. He continued to pile on the pounds when he entered the world of politics as MP for West Bromwich East (despite short-lived flirtations with fad diets and fitness classes). By December 2014, his bathroom scales had tipped to 22 stone. After being diagnosed with type 2 diabetes in late 2015, he decided to take control of his diet and exercise. He started to feel better quickly and within a short time his long-term blood sugar levels were within normal range. By July 2018, he came off medication.
This redesigned and expanded third edition of Diabetes Snacks, Treats, and Easy Eats for Kids offers even more simple, delicious recipes for healthy, well-balanced diets. Since the book was first published in 2006, the prevalence of diabetes in children has continued to increase. Children under age 19 have seen a 21 percent increase in Type 1 cases, and children ages 10-19 have seen a 30 percent increase in cases of Type 2-a disease that used to be considered an adult condition. But kids will be kids, and when they come home from school, they want a snack that's simple, satisfying, and occasionally sweet. When it comes to dinner, they usually don't have the time or the taste for fancy meals. With this in mind, author Barbara Grunes has developed more than 150 recipes for snacks and meals that kids really like and that stay within diabetic guidelines. Grunes's goal is to help all kids enjoy food that is good for them-even if they have diabetes. Each recipe includes the nutritional information readers need, whether they count carbs or use the exchange method. With recipes like Pizza Puffs, Spud Pancakes, Chicken Fajitas, Ice Cream Cone Cupcakes, and Fruit Turnovers, this book proves that everyone can enjoy familiar and delicious food together. After all, it's not about "good," "bad," or "forbidden" foods-it's about readers feeding their families sensibly.
This title features expert advice about managing diabetes, with a full guide to healthy living and over 80 delicious recipes. It is a guide to living with diabetes, with helpful advice on managing the condition, alleviating the symptoms, controlling weight and reducing medication. It includes 80 recipes to inspire the diabetic cook, with tempting meals that can be enjoyed with family and friends, such as Wild Mushroom and Fontina Tarts, Grilled Mackerel with Dahl, and Baked Ricotta Cakes with Red Fruits. It brings together the latest thinking on dietary and lifestyle advice to help explain the condition, provide guidelines on what and when to eat, and how to tailor food intake to individual requirements. It covers full nutritional notes, including glycemic load, are supplied for every recipe, with over 400 photographs, including step-by-step sequences for every dish. This authoritative, practical recipe book begins with a detailed introduction on living with diabetes, the necessity of weight control and the importance of exercise. Carbohydrate counting, fat reduction, cholesterol control and portion management are all covered, as is the complex but vital low-glycaemic index. There is a special section on diabetes in children, as well as advice and support for how to manage the condition in puberty, pregnancy and throughout the aging process. The 80 recipes that follow provide everything that is needed for a varied and enjoyable diet, with recipes that friends and family will enjoy eating. Chapters include healthy and sustaining snacks, as well as breakfasts, main dishes, appetizers and puddings. To prove that diabetes does not mean denial, all these satisfying recipes are packed with taste as well as goodnes,s and are presented with full breakdowns of nutritional values.
Numerous research programs have developed over the last decade to improve the understanding of the causes, prevention and treatment of diabetes and its complications. Efficient synthesis of the data and information from these diverse sources is crucial to prioritize interventions and assemble resources for the implementation of public health programs. This book meets this need and builds on previous works to reflect the evolution of science related to diabetes public health. Through compelling evidence related to the current health and economic impact of diabetes, the book provides effective approaches to prevent and manage diabetes through the practice of public health. It combines state-of-the-art descriptions of risk factors and complications, effective and cost-effective approaches to prevention and treatment, translational research, and genomics to give a comprehensive and up-to-date analysis on diabetes public health. Critical review and synthesis of influential epidemiologic studies and consensus statements, expected future advances in trials and technologies, and public health information resources are also highlighted topics. With significant attention to diabetes control in the U.S. and North America, Diabetes Public Health should be required reading for public health practitioners and researchers, as well as anyone involved in health policy, administration and management. It will also be of interest to academics in the field of diabetes and other chronic diseases.
The Forensic Aspects of Hypoglycaemia succinctly covers the medicolegal considerations of hypoglycaemia in a variety of scenarios including driving fatalities, petty crime, homicide and suicide. Covering the definitions and diagnosis of hypoglycaemia to its bearing on criminal behavior, this book draws on the author's extensive experience and contains a wealth of information for physicians and lawyers, including cases from the author's past and notable cases in the public domain.
Historically, clinical decisions in renal medicine have been challenged by the scarce availability of robust supportive evidence. Not only are the number of randomized controlled trials (RCTs) in Nephrology the third lowest amongst the medical specialties but in many instances the trials themselves are of poor quality. In addition, practice has been further influenced by extrapolation from the outcomes of general population clinical trials which exclude renal patients. The difference between the ideal trial participant and real complex cases encountered in daily practice is well recognized and further compounded in renal patients with complex pathophysiology - this ultimately makes decision making in this subset of patients a real challenge. Recently, there has been a growing interest in conducting well designed RCTs in different areas of renal medicine. However, though clinical guidelines are helpful in providing the clinicians with a frame of best available evidence for a clinical condition, it denies the unique nature of each individual patient. This book offers a thorough and critical appraisal and evaluation of the key published clinical trials that have shaped current practice in nephrology, dialysis and transplantation. It will help the practicing physician close the gap between the inflexible and generalized nature of clinical guidelines and the day-to-day clinical decision-making for individual patients. It will provide the clinician with the tools required to investigate and extract the appropriate guidance to apply to individual cases in daily practice. Moreover, it will help improve the ability of junior colleagues to appraise available evidence in a systematic way when there is lack of local guidelines or when the guidelines are difficult to apply due to logistic constraints or barriers. Lastly, this book will serve as a reference for key clinical trials in different areas of renal medicine together with literature and authors views of these trials and their impact on changing practice.​Â
The world is beset by a pandemic of obesity and type 2 diabetes and the need for new drugs is startlingly clear; recent years have seen a huge increase in research activity to fill this gap. The development of new drugs for diabetes and obesity must be founded upon a sound appreciation of the pathophysiology of these common disorders. The dual defects of insulin resistance and impaired insulin secretion are fundamental to the pathogenesis and progression of obesity-associated type 2 diabetes. There is a need to explain how new drugs can counter insulin resistance and insulin deficiency to a broad range of professionals, from clinical scientists active in early (and later) phase drug development to specialist physicians and increasingly primary care doctors who must tailor drug regimens to the individual patient. Clinical research methods for measuring insulin action and insulin secretion have become well-established in proof-of-mechanism studies; however, selection of the best techniques is by no means straightforward. The purpose of the book is to aid the selection of the most appropriate techniques for assessing insulin action, insulin secretion and body composition in humans (with particular reference to new drugs) in phase 1 and 2 studies and aid the understanding of drug effects and non-drug treatment strategies on key biochemical-hormonal defects of obesity and type 2 diabetes. The book will assume a working knowledge of human physiology relating to glucose metabolism and will be of interest to biomedical scientists, pharmacologists, academics involved in metabolic research and clinicians practicing in these specialties. |
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