'It is an excellent advocate for both reference publishing and for the belief system it represents' - Reference Reviews

'This work is a crucial source for specialists...Highly recommended' - G. J. Reece, American University, Choice

The Routledge Encyclopedia of Buddhism is a complete up-to-date one-volume desk reference, documenting the history, doctrines, schools, rituals, sacred places, basic ideas and concepts, and globalization of the entire Buddhist tradition. In addition, it provides bibliographic references to the leading scholarship by scholar from around the world. As such, it is an indispensable tool for students, teachers, and researchers from a wide range of disciplinary backgrounds, as well as to the general reader.

The Encyclopedia is characterized by its wide range of contents, primary sources, and both the depth and quality of its entries. It allows its readers to quickly access information on all topics included in the volume.

It covers the study of Buddhism, Buddhist canons and literature, Buddha, Dharma, Sangha, Nikaya Buddhism, Mahayana Buddhism, Vajrayana Buddhism, Buddhist meditational systems, sacred places in Buddhism, practices and rituals, biographies of famous Buddhists (including ideal types), Buddhist ethics, Buddhist art(s), engaged Buddhism, Buddhism and technology, women in Buddhism, Buddhism in India, South and Southeast Asia, Tibet, China, Korea, Japan, and Buddhism in the Western World.

All readers of the Encyclopedia will benefit from a scholarly but readable work that lends itself to being approached from almost any starting point, and guides the reader to an increased knowledge of Buddhism through very easy access to all relevant materials.

Dopamine is a small molecule traditionally regarded as a brain-derived neuronal modulator implicated in many neurological and psychiatric disorders. Outside the brain, dopamine fulfills all the criteria of a circulating hormone which affects normal and abnormal functions of multiple organs and regulatory systems and is also involved in many aspects of cancer formation and progression. This book provides a much needed systematic account of dopamine as an endocrine and autocrine/paracrine hormone and fills a major gap in the overall understanding of the production, distribution and actions of this very important molecule. Key Features: Explores the many different faces of dopamine as autocrine, paracrine and endocrine molecule Documents the adverse effects of antipsychotics on dopamine functions Reviews the many ways dopamine affects the cardiovascular, renal and reproductive systems Provides updates on receptor oligomerization and signaling Examines the role of dopamine in tumorigenesis Related Titles Jones, S. ed. Dopamine - Glutamate Interactions in the Basal Ganglia (ISBN 978-0-3673-8197-4) Luo, L. Principles of Neurobiology (ISBN 978-0-8153-4494-0) Sidhu, A. et al., eds. Dopamine Receptors and Transporters (ISBN 978-0-8247-0854-2)

Why do governments choose to negotiate indigenous land claims rather than resolve claims through some other means? In this book Scholtz explores why a government would choose to implement a negotiation policy, where it commits itself to a long-run strategy of negotiation over a number of claims and over a significant course of time.

Through an examination strongly grounded in archival research of post-World War Two government decision-making in four established democracies - Australia, Canada, New Zealand, and the United States - Scholtz argues that negotiation policies emerge when indigenous people mobilize politically prior to significant judicial determinations on land rights, and not after judicial change alone. Negotiating Claims links collective action and judicial change to explain the emergence of new policy institutions.

From an acclaimed author in the field, this is a compelling study of the origins and history of the disease commonly seen as afflicting young unmarried girls. Understanding of the condition turned puberty and virginity into medical conditions, and Helen King stresses the continuity of this disease through history, depsite enormous shifts in medical understanding and technonologies, and drawing parallels with the modern illness of anorexia. Examining its roots in the classical tradition all the way through to its extraordinary survival into the 1920s, this study asks a number of questions about the nature of the disease itself and the relationship between illness, body images and what we should call'normal' behaviour. This is a fascinating and clear account which will prove invaluable not just to students of classical studies, but will be of interest to medical professionals also

Vaccines are a debate, whether we want them to be or not. With a clear-eyed approach to their science and history, HOW VACCINES WORK demystifies the strange and intricate world of vaccines: it explains what a vaccine is, how they are developed and what happens when they meet our bodies. David Miles has worked in immunology - as a scientist, teacher and communicator - for two decades. Taking his expert understanding of the field and the questions he is asked by ordinary people, HOW VACCINES WORK combines a field guide to the vaccines we currently receive with the historical background to their development, along with thrilling storytelling and comprehensive, reassuring debunking of the most common vaccination myths.

Chemotherapy and radiotherapy for cancer can have devastating side effects on the skin of a patient. This innovative guide for both dermatologists and oncologists gives a good introduction both to therapy regimes and to dermatological management for medical professionals treating their patients.

Do we really need to wear masks? From the New York Times Bestselling authors of Plague of Corruption comes the must-read guide on masks and re-opening following the COVID-19 pandemic. THE CASE AGAINST MASKS is the book all America needs to be reading as we emerge from the COVID-19 pandemic. Written by New York Times bestselling authors Dr. Judy Mikovits and Kent Heckenlively, this book reviews the evidence for and against widespread public masking as provided by the Centers for Disease Control and the Mayo Clinic, as well as top scientific publications such as the New England Journal of Medicine and The Lancet. This debate needs to take place without fear and paranoia. Important questions raised in this book are the effect of masks on oxygen and carbon dioxide levels, how SARS-CoV-2 spreads, the effectiveness of various types of masks, those who are most vulnerable to COVID-19, and whether our children should go back to school in the fall, and if so, what measures they should take. The authors' previous book, PLAGUE OF CORRUPTION, was the runaway science bestseller of 2020, and the authors bring that same passion and attention to detail to the mask question. As politicians and bureaucrats of all stripes are weighing in on this question, with some placing their cities and states under mandatory masking provisions, we need to understand the science behind their decisions. Are such measures a reasonable response to current circumstances, or is it a dramatic overreach, which in many cases might make the situation even worse? America desperately needs this public conversation to take place with the best science we have available. As Americans have always done during difficult times, we must summon the courage to have these challenging conversations.

Infection control is fundamental to delivering effective health and social care at all levels. However, health and social care professionals' actual behaviour can sometimes seem intractable to the most rigorous training and promotion of safe practice - including even basic hygiene precautions. Many have identified this problem, but few have addressed why it occurs and how practices can lastingly be changed. This book reaches beyond a prescriptive approach to infection control behaviour, examining the psychosocial forces that affect individual and group behaviours in practice. It gives a strong theoretical framework for practitioners, supervisors and managers to reflect upon and challenge behaviour, before providing practical advice on how to create, supervise and promote genuinely consistent safe practice. This book aims to challenge fundamentally the way health and social care professionals, supervisors and managers approach infection control and hygiene - and in doing so to dramatically improve the health and safety of their patients, clients, colleagues and the public.

*Offers a comprehensive clinical guide to combination techniques for skin surgery, including information on alternatives, anatomical danger zones, complications, and follow-up results *Shows how dermatologic surgeons can improve their results for patients *Documents what can be achievd by often neglected procedures

A practical and up-to-date guide to pacemaker technology and its clinical implementation As the field of cardiology continues to advance and expand, so too does the technology and expertise behind today's electrophysiological devices. Cardiac Pacing, Defibrillation and Resynchronization has been assembled by international specialists to give all those caring for patients with heart disorders a clear and informative guide to the pacemakers and clinical methods of today. Now in its fourth edition, this essential resource: Explains different methods of pacemaker implementation in a straightforward and easy-to-follow manner Explores the most common challenges faced by working clinicians Features more than 750 illustrative graphics Contains data on the efficacy and long-term outcomes of different device models Covers new technology and clinical trial data Written for cardiologists, cardiac pacing caregivers, and those preparing to take their electrophysiology board examinations, Cardiac Pacing, Defibrillation and Resynchronization offers a complete exploration of electrophysical devices and their vital role in modern-day cardiology.

Key Features: * Provides a comprehensive and complete resource on Leishmaniasis on various aspects of the disease, distilling credible information from available literature coupled with historical references. * Follows a model approach for handling emerging infectious diseases for the benefit of clinicians and front-line workers. * Discusses the unique problem of skin localizing visceral parasites and provides basic principles of management for other infectious diseases and vector-borne infections.

The diagnostic and therapeutic achievements in radiopharmaceuticals and nuclear medicine instrumentation - PET, SPECT, MR, CT and their hypbrids PET-CT and SPECT-CT - are the result of the interdisciplinary research efforts of cell-biologists, chemists, pharmacologists, physicists, computer-scientists, engineers, nuclear medicine physicians, and oncologists. The clinical implications of these achievements have made nuclear medicine indispensable in the management of cancer. This superbly illustrated text on modern nuclear medicine applications in the diagnosis and treatment of cancer describes the state of the art and the current position of nuclear medicine in the light of these recent developments. It is intended as a valuable update also for non-nuclear medicine specialists working in oncology. Nuclear medicine as part of molecular imaging and therapy has changed radically in the last decade. The growing importance and clinical impact of these changes in the near future has impelled the internationallyrenowned editors and contributors to put them on record in "Advances in Nuclear Oncology,"

In the growing field of neuro-oncology, the past few years have witnessed rapid advances in tumor classification, treatment modalities, and the role of neurologists and neuro-oncologists. Neuro-Oncology for the Clinical Neurologist is a first-of-its-kind resource that focuses on patient-clinical scenarios relevant to the practicing neurologist-bringing you up to date with everything from basic principles and neuro-oncology imaging consults to neurologic complications of radiation, systemic, and immune-based therapies, and much more. Focuses on the clinical management of patients typically encountered by neurologists and neurology trainees. Provides clinically relevant updates in five key areas of neuro-oncology: primary CNS tumors, brain and leptomeningeal metastases, inherited tumor syndromes of the nervous system (e.g. neurofibromatosis), paraneoplastic and immune-mediated neurological complications of cancer, and neurological complications of cancer treatments. Includes a summary of clinical pearls and a reference list of clinical cases. Anchors each chapter with patient cases and clinical scenarios, provides evidence-based discussion, and explains patient management. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

This book provides a first comprehensive summary of the basic principles, instrumentation, methods, and clinical applications of three-dimensional dosimetry in modern radiation therapy treatment. The presentation reflects the major growth in the field as a result of the widespread use of more sophisticated radiotherapy approaches such as intensity-modulated radiation therapy and proton therapy, which require new 3D dosimetric techniques to determine very accurately the dose distribution. It is intended as an essential guide for those involved in the design and implementation of new treatment technology and its application in advanced radiation therapy, and will enable these readers to select the most suitable equipment and methods for their application. Chapters include numerical data, examples, and case studies.

Epidemiological studies show that cancer incidence is far more dependent on the conditions of life than previously supposed. Classically, cancers occurred with heavy exposure to a specific occupational hazard, or were associated with habits. In some instances, research shows, the incidence of cancer falls when the method of work or the associated habit is changed. In short, variation in incidence is now known to be the rule rather than the exception in cancer. No cancer that occurs with even moderate frequency, occurs everywhere and always to the same extent. Sometimes it is even epidemic, similar in scale to an epidemic of infectious disease, but modified by the fact that the induction period may be as much as thirty years.

Prevention of cancer is now coming to be regarded as a practicable alternative to its cure. We remain almost totally ignorant of how cancer is produced at the cellular level and, until we know this, our methods of prevention are liable to be cumbersome and inefficient. Ethical considerations and the time scale of the disease make it impossible to obtain experimental evidence in man and what action to take has been determined from observing nature's experiments and by analogy from experiments in animals.

The evidence from epidemiological studies is of particular interest. Such studies suggest relationships that would never be thought of in the ordinary course of laboratory work and results that are directly relevant to the problems of human disease. The large numbers at risk and the intensity of the medical care to which people with cancer are subjected, make it possible to recognize relatively small improvements. Such practical decisions, based on information thus obtained, have largely eliminated the risk of cancer due to occupational hazards in several industries.

"Richard Doll" (1912-2005) was a British psychologist and one of the most prominent epidemiologists of the twentieth century. Throughout out his research he was able to link smoking with health problems and was the first individual to link smoking with lung cancer and increased risk of heart disease. He also studies the relationship between asbestos and lung cancer and radiation and leukemia. He is the author of many books, including "The Causes of Cancer: Quantitative Estimates of Avoidable Risks of Cancer in the United States Today" and "Tobacco and Health."

In a digital world where the public's voice is growing increasingly strong, how can health experts best exert influence to contain the global spread of infectious diseases? Digital media sites provide an important source of health information, however are also powerful platforms for the public to air personal experiences and concerns. This has led to a growing phenomenon of civil skepticism towards health issues including Emerging Infectious Diseases and epidemics. Following the shift in the role of the public from recipients to a vocal entity, this book explores the different organizational strategies for communicating public health information and identifies common misconceptions that can inhibit effective communication with the public. Drawing on original research and a range of global case studies, this timely volume offers an important assessment of the complex dynamics at play in managing risk and informing public health decisions. Providing thought-provoking analysis of the implications for future health communication policy and practice, this book is primarily suitable for academics and graduate students interested in understanding how public health communication has changed. It may also be useful to health care professionals.

Brachytherapy has become the modality of choice for several cancer localizations, minimizing the possibility of unacceptable risks for healthy tissues and providing a more cost-effective and convenient treatment for patients. Written by leading experts in the physics, development, and implementation of brachytherapy, The Physics of Modern Brachytherapy for Oncology discusses the subject in detail, covering its definition, the basic physics of radiation interaction with matter, radionuclides, sources and source production, calibration and dosimetry protocols as well as experimental dosimetry methods appropriate for practical use. Logically organized, the book begins with basic information, including quantities and units, followed by fundamental atomic and nuclear physics. It also provides the historical background of brachytherapy physics. The next several chapters discuss the radionuclides used in brachytherapy, reflecting upon past (radium), present (iridium or cobalt), and future (ytterbium) methods. The book proceeds to examine source calibration and dosimetry protocols for dose rate calculation while the final chapters explore more recent processes, including Monte Carlo-aided, experimental, and gel dosimetry. The appendices provide useful tables of isotopes, unit conversions and physical constants, brachytherapy sources, TG-43 and TG-43 U1 data tables, and dose rate tables. Detailing the physics behind brachytherapy treatment, The Physics of Modern Brachytherapy for Oncology is essential reading for researchers, practicing radiation oncologists, and medical physicists who want to keep abreast of the developments in this changing field as well as for postgraduate students in medical physics.

Pharmacogenetics is becoming increasingly relevant in the diagnosis, treatment, and recovery of cancer patients. A major problem facing oncologists is the outstanding varied efficacy of treatment. Promising advances in pharmacogenetics have allowed the development of effective agents which will enable personalized cancer chemotherapy to become routine for the clinical practice.

Written by experts in the field and combining information that is unable to be found in a single source volume, Pharmacogenetics of Breast Cancer

• combines a complete overview of pharmacogenetics and how it relates to breast oncology for diagnosis, treatment, and the recovery of patients using an individualized therapy model
• is the first single source reference demonstrating the application of pharmacogenetics in the care of breast cancer patients
• enables physicians a coherent interpretation of the emerging science of pharmacogenetics, aiding them to incorporate individual therapies in their own practice
• gives practical guidance on various forms of specimen collection, tissue selection, and handling procedures

Ancient therapeutic systems have played a tremendous role in health preservation all around the globe for thousands of years; even the earliest humans on earth had used these approaches along with simple surgical procedures for the betterment of their health. Complementary and Alternative Medicinal Approaches for Enhancing Immunity examines various aspects of health and diseases and the importance of basic but essential factors for the preservation of health and management of diseases. Concisely written, the author discusses ancient ways to enhance self-healing abilities and stimulate the immune system such as, fasting, meditation, acupuncture, cupping therapy, balneotherapy and aromatherapy. The importance of nutrition and diet is also examined as it plays a crucial role in the prevention and causation of diseases. Additional features include: Discusses how the integration of various CAM modalities helps in enhancing self-healing abilities and boosts the human immune system. Contains various topics from different systems of medicines that are taught widely as individual courses or discussed broadly in several institutes. Reviews Eastern pharmacotherapy and how using certain herbs, minerals, and animal-based products aids in maintaining health and alleviating diseases. Using evidence-based knowledge taken from ancient literature and recently published articles, this book will inform readers on the importance of holistic health approaches and some ancient treatment modalities that enhance the immune system to combat diseases.

Key Features: * Explores a highly topical concept of vaccines in a comprehensive and easy to read manner. * Engages the readers with relatable and interesting anecdotes. * Provides a balanced, factual counter to the huge amount of current vaccine misinformation.

Chemotherapy and radiotherapy for cancer can have devastating side effects on the skin of a patient. This innovative guide for both dermatologists and oncologists gives a good introduction both to therapy regimes and to dermatological management for medical professionals treating their patients.

Recent advances in immunology and biology have opened new horizons in cancer therapy, included in the expanding array of cancer treatment options, which are immunotherapies, or cancer vaccines, for both solid and blood borne cancers. Cancer Vaccines: Challenges and Opportunities in Translation is the first text in the field to bring immunotherapy treatments from the laboratory trial to the bedside for the practicing oncologist. Cancer Vaccines: Challenges and Opportunities in Translation: Critically analyzes the most promising classes of investigational immunotherapies, integrating their scientific rationale and clinical potential Discusses "theranostics" as pertaining to immunotherapy, i.e., using molecular diagnostics to identify patients that would most likely benefit from a therapy Presents the new paradigm of biomarker guided R&D and clinical development in immunotherapy of cancer Reviews bottlenecks in translational process of immunotherapies and offers strategies to resolve them

More than two decades into the global HIV epidemic, many HIV positive patients who have access to antiretroviral medications are graying. These patients and their clinicians now face another set of complex health issues related to aging. HIV and Aging examines the known effects of HIV and HIV medications on older patients and on their immune systems. The book explores the coalescence of aging and HIV on neurologic, psychiatric, cardiovascular, endocrine, renal, and pulmonary systems and oncology.

Written by some of today 's top experts, HIV and Aging answers questions like:

• What are the similarities with immune system changes that occur with aging and those associated with HIV?
• What effects do HIV and HIV medications have on cardiovascular health?
• What do we know about drug interactions between antiretrovirals and medicines used to treat diseases of aging?

'This book will make you love her as much as I do' FORMER PRESIDENT BILL CLINTON 'Breath-taking courage and compassion [...]a beautiful book' THE SUNDAY TIMES 'A renegade Florence Nightingale cares for the ill in a remarkable tale of compassion and combating prejudice' GUARDIAN 'An extraordinary tale' EVENING STANDARD 'If I have one message with this book it's that we all have to care for one another. Today, not just in 1986. Life is about caring for each other, and I learned more about life from the dying than I ever learned from the living. It's in an elephant ride, it's in those wildflowers dancing on their way to the shared grave of two men in love, and it's in caring for that young man who just needed information without judgement.' In 1986, 26-year-old Ruth Coker Burks visits a friend in hospital when she notices that the door to one of the patient's rooms is painted red. The nurses are reluctant to enter, drawing straws to decide who will tend to the sick person inside. Out of impulse, Ruth herself enters the quarantined space and begins to care for the young man who cries for his mother in the last moments of his life. And in doing so, Ruth's own life changes forever. As word spreads in the community that she is the only person willing to help the young men afflicted by the growing AIDS crisis, Ruth goes from being an ordinary young mother to an accidental activist. Forging deep friendships with the men she helps, Ruth works to find them housing and jobs, and then funeral homes willing to take their bodies - often in the middle of the night. She prepares and delivers meals to 'her guys,' supplementing her own income with discarded food found in the dumpsters behind supermarkets. She defies local pastors and the medical community to store rare medications for her most urgent patients, and teaches sex education to drag queens after hours at secret bars. Emboldened by the weight of their collective pain, she fervently advocates for their safety and visibility, ultimately advising Governor Bill Clinton on the national HIV-AIDS crisis, and in doing so becomes a beacon of hope to an otherwise spurned group of ailing gay men on the fringes of society. Ruth kept her story a secret for years, fearful of repercussions within her deeply conservative community. But at a time when it's more important than ever to stand up for those who can't, Ruth has found the courage to have her voice - and the voices of those who were stigmatised, rejected and abandoned - heard.

The potential value of artificial neural networks (ANN) as a predictor of malignancy has begun to receive increased recognition. Research and case studies can be found scattered throughout a multitude of journals. Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management brings together the work of top researchers - primarily clinicians - who present the results of their state-of-the-art work with ANNs as applied to nearly all major areas of cancer for diagnosis, prognosis, and management of the disease. The book introduces the theory of neural networks and the method of their application in oncology. It is not an exercise in ANN research, but the presentation of a new technique for diagnosing and determining the treatment of cancers. The authors have included almost all cancers for which there exist ANN applications. When the data available is ill-defined and the development of an algorithmic solution difficult, neural networks provide a non-linear approach which helps sift through the maze of information and arrive at a reasonable solution. Highly interdisciplinary in nature, this book provides comprehensive coverage of the most important materials relating to the applications of ANNs in the cancer field. With contributions from prominent research centers worldwide, it serves as an introduction to how neural networks can be used for accurate prediction or diagnosis and shows why neural networks are more accurate. Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management gives you an understanding of this new tool, its applications, and when it should be used.