Through a fusion of personal experience and art, the contributors help us understand the lived realities of individuals with head and neck cancer. Featuring original art from Ingrid Bachmann, Sean Caulfield, Jude Griebel, Jill Ho-You, Heather Huston, and Bradley Necyk, this collaborative, interdisciplinary exploration draws together the voices of patients, health care practitioners, researchers, and artists to offer a more holistic-more human-understanding of cancer treatment and its aftermath. Art-Medicine Collaborative Practice will resonate with people with head or neck cancer as well as medical practitioners who aid in their healing process. It is an important book for all those in the health professions and medical humanities, as well as artists, arts-based researchers, and those interested in the areas of health and visual communication and knowledge translation. Contributors: Ingrid Bachmann, Pamela Brett-MacLean, Sean Caulfield, Kimberly Flowers, Jude Griebel, Bahaa Harmouche, Jill Ho-You, Heather Huston, Bernie Krewski, Lianne McTavish, Suresh Nayar, Bradley Necyk, Leslie O'Connor-Parsons, Kyle Terrence, Helen Vallianatos, Minn N. Yoon

The interactions of cells with their surrounding extracellular matrix (ECM) plays a pivotal role in driving normal cell behavior, from development to tissue differentiation and function. At the cellular level, organ homeostasis depends on a productive communication between cells and ECM, which eventually leads to the normal phenotypic repertoire that characterize each cell type in the organism. A failure to establish these normal interactions and to interpret the cues emanating from the ECM is one of the major causes in abnormal development and the pathogenesis of multiple diseases. To recognize and act upon the biophysical signals that are generated by the cross talk between cells and ECM, the cells developed specific receptors, among them a unique set of receptor tyrosine kinases (RTKs), known as the Discoidin Domain Receptors (DDRs). The DDRs are the only RTKs that specifically bind to and are activated by collagen, a major protein component of the ECM. Hence, the DDRs are part of the signaling networks that translate information from the ECM, and thus they are key regulators of cell-matrix interactions. Under physiological conditions, DDRs control cell and tissue homeostasis by acting on collagen sensors; transducing signals that regulate cell polarity, tissue morphogenesis, cell differentiation, and collagen deposition. DDRs play a key role in diseases that are characterized by dysfunction of the stromal component, which lead to abnormal collagen deposition and the resulting fibrotic response that disrupt normal organ function in disease of the cardiovascular system, lungs and kidneys, just to mention a few. In cancer, DDRs are hijacked by tumor and stromal cells to disrupt normal cell-collagen communication and initiate pro-oncogenic programs. Importantly, several cancer types exhibit DDR mutations, which are thought to alter receptor function, and contribute to cancer progression. Therefore, the strong causative association between altered RTK function and disease it is been translated today in the development of specific tyrosine kinase inhibitors targeting DDRs for various disease conditions. In spite of the accumulating evidence highlighting the importance of DDRs in health and diseases, there is still much to learn about these unique RTKs, as of today there is a lack in the medical literature of a book dedicated solely to DDRs. This is the first comprehensive volume dedicated to DDRs, which will fill a gap in the field and serve those interested in the scientific community to learn more about these important receptors in health and disease.

Dieses Buch fasst therapieorientiert die modernen Moeglichkeiten und neuesten Erkenntnisse auf dem Gebiet der Gefassdiagnostik zusammen. Es schlagt weiterhin die Brucke von der sonographischen Gefassdiagnostik zur Therapie. Ultraschall in der Gefassdiagnostik fuhrt den Anfanger vom rationalen Untersuchungsablauf zur sicheren Befunderhebung. Erfahrene Nutzer profitieren von Tipps und Tricks zur zeiteffizienten Diagnostik, der Beschreibung seltener Gefasserkrankungen und der Darstellung der therapeutischen Konsequenz aus den Ultraschallbefunden. In der Neuauflage ist besonders berucksichtigt: - Die Duplexsonographie als Moeglichkeit zur Visualisierung der normalen und pathologischen Hamodynamik zu verstehen, ist ein besonderes Anliegen des Buches ("Lernen, Dopplerspektren richtig zu lesen"). - Konzepte zur zeiteffizienten Untersuchung zum Teil vom Autor selbst entwickelt - Methodenkritische Diskussion von Diskrepanzen in Ultraschallstudien sowie in Vergleichsstudien mit radiologischen Verfahren. - Methodische Neuerungen wie die Kontrastmittelsonographie werden vorgestellt und die diagnostischen Moeglichkeiten im klinischen Alltag detailliert gefassbezogen diskutiert. - Neue wissenschaftliche Erkenntnisse werden methodenkritisch reflektiert, auf Ihre Wertigkeit in Diagnostik und Therapie planung uberpruft und Kontroversen diskutiert. - Ultraschall in der Stufendiagnostik rational bis zu Therapie einsetzen

The Cerebellum provides a concise, accessible overview of modern data on physiology and function of the cerebellum as it relates to learning, plasticity, and neurodegenerative diseases. Encompassing anatomy and physiology, theoretical work, cellular mechanisms, clinical research, and disorders, the book covers learning and plasticity while introducing the anatomy of the cerebellum. Known and proposed "functions of the cerebellum" are addressed on clinical, physiological, cellular, and computational levels, providing academics, researchers, medical students, and graduate students with an invaluable reference.

This is a reproduction of a book published before 1923. This book may have occasional imperfections such as missing or blurred pages, poor pictures, errant marks, etc. that were either part of the original artifact, or were introduced by the scanning process. We believe this work is culturally important, and despite the imperfections, have elected to bring it back into print as part of our continuing commitment to the preservation of printed works worldwide. We appreciate your understanding of the imperfections in the preservation process, and hope you enjoy this valuable book.

Der zweite Band des Gebietes Drogen der Neuauflage enthalt in alphabetischer Reihenfolge von E-O Monographien uber Arzneipflanzengattungen. Jede Monographie umfasst die fur die pharmazeutische Praxis wichtigen Arzneipflanzen mit den dazugehoerigen allopathischen und homoeopathischen Drogen. In den Monographien werden Aussagen uber die Botanik, Chemotaxonomie, Analytik, Wirkung, medizinische Anwendung und Toxikologie gemacht. Von besonderer Bedeutung sind Drogen des Deutschen Arzneibuchs, des Homoeopathischen Arzneibuchs und von in Europa gultigen Arzneibuchern.

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. PreTest is the closest you can get to seeing the USMLE Step 1 before you take it! 500 USMLE-type questions and answers! "This book is a wonderful resource for second year medical students taking pathology as well as medical students in their clinical years. It is a good review and highly relevant to what I am seeing in the hospital." -- Sheree Perron, Third Year Medical Student, Eastern Virginia Medical School "I especially liked how there was a wide range of difficulty with questions. The pictures that accompanied several of the questions were very clear, and represented what students are likely to see on the actual exam." -- Jodie Bachman, Third Year Medical Student, UMDNJ School of Osteopathic Medicine Great for course review and the USMLE Step 1, Pathology: PreTest asks the right questions so you'll know the right answers. You'll find 500 clinical-vignette style questions and answers along with complete explanations of correct and incorrect answers. The content has been reviewed by students who recently passed their exams, so you know you are studying the most relevant and up-to-date material possible. No other study guide targets what you really need to know in order to pass like PreTest! Content that covers all the must-know topics: High-Yield Facts,General Pathology,Cardiovascular System,Hematology,Respiratory System,Head and Neck,Gastrointestinal System,Urinary System,Reproductive Systems,Endrocrine System,Skin,Musculoskeletal System,Nervous System

The chapters in this important book touch upon clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. They include localisation of ictal and postictal behaviours; neuroendocrine aspects of epilepsy; psychiatric and psychosocial aspects of epilepsy; behavioural aspects of epilepsy surgery; cognitive and affective effects of seizure treatment and functional imaging and animal models.

Biological Action of Low Doses of Radiation - A Novel View on the Problem

Highlighting the latest and the most timely aspects of Alzheimer's disease research, this text will enable scientists in related research fields, as well as physicians working with Alzheimer's disease patients, to obtain a quick and complete overview of the current state of the art in one of the most exciting fields in neuroscience research. Leading scientists have contributed articles focusing on key developments in this field. This includes an overview about the pathology, the genetics of familial Alzheimer's disease, proteolytic generation and aggregation of amyloid -peptide, presenilins, risk factors such as ApoE, and transgenic animal models. Some of the latest developments in Alzheimer's disease research, including the effect of presenilin knock outs on amyloid -peptide generation, are also included.