Winners and underdogs in scientific dispute - not always the better argument decides who is going to enter the annals. The end justifies the means, also in science when one or the other scientist tries to distinguish himself.

Provides comprehensive research ideas about Edge-AI technology that can assist doctors in making better data-driven decisions and will provide insights to researchers about healthcare industry, trends and future perspective. Examines how healthcare systems of the future will operate, by augmenting clinical resources and ensuring optimal patient outcomes. Provides insight about how Edge-AI is revolutionizing decision making, early warnings for conditions, and visual inspection in healthcare. Highlight trends, challenges, opportunities and future areas where Healthcare informatics deal with accessing vast data sets of potentially life-saving information.

A comprehensively revised and updated 2nd Edition of the WJEC Biology for A2 Student Book. // Endorsed by WJEC, this new edition of the Student Book offers high quality support you can trust // Straightforward and concise coverage of the specification, so students can be confident they are covering what's needed for exam success // New Test Yourself section at the end of each chapter to reinforce knowledge with answers provided in the book // Now includes detailed explanations of the Assessment Objectives with examples of how the AOs are approached in exam questions // New section on Answering exam questions at the end of each unit gives guidance on command words and how to approach each question // New Exam Practice questions at the end of each unit are taken from actual Eduqas past papers with answers provided in the book // New Theory Check feature accompanies the practical tasks in the book and helps students check their understanding of biology in relation to practical tasks // Enhanced support for practical skills enable students to embed their understanding of practical work // Increased maths support with maths skills and techniques regularly tested throughout // Clear explanations and diagrams throughout

Forensic taphonomy is the study of the postmortem changes to human remains, focusing largely on environmental effects-including decomposition in soil and water and interaction with plants, insects, and other animals. While other books have focused on subsets such as forensic botany and entomology, Manual of Forensic Taphonomy is the first update of the entire domain in more than ten years and the first book to consider distinguishing among multiple types of taphonomic changes. Edited by two of the most distinguished experts in the field, this volume examines taphonomic alterations to bone and related taphonomic processes common to cases of forensic interest. Specific chapters address a range of issues related to: Varying burial environments Animal scavenging and transport Fluvial and human transport Cultural modifications Marine environments Subaerial weathering Thermal alteration Recovery methods used in collecting the remains The book discusses inherent variations in survivability of different bones, degradation of DNA in different environments, and organisms involved in soft-tissue decomposition which result in skeletonization. It also describes microscopic alterations, color changes, macroscopic physical damage of multiple types, and bone loss through dispersal away from the location of initial body deposition. The authors present methods that can be employed to determine the timing of taphonomic damage (perimortem vs. postmortem) as well as checklists for the collection of microscopic and macroscopic taphonomic data. The ability to recognize taphonomic characteristics and discriminate between osseous alterations with similar appearances but dissimilar origins is essential to those engaged in the analysis of skeletal remains. This volume is an ideal guide for students and non-specialists as well as a reference manual for professionals.

This volume investigates mediated lives and media narratives during the COVID-19 pandemic, with Asia as a focus point. It shows how the pandemic has created an unprecedented situation in this globalized world marked by many disruptions in the social, economic, political and cultural lives of individuals and communities - creating a 'new normal'. It explores the different media vocabularies of fear, panic, social distancing, and contagion from across Asian nations. It focuses on the role media played as most nations faced lockdowns and unique challenges during this crisis. From healthcare workers to sex workers, from racism to nationalism, from the plight of migrant workers in news reporting to state propaganda, this book brings critical questions confronting media professionals into focus. The volume will be of critical interest to scholars and researchers of media and communication studies, politics, especially political communication, social and public policy, and Asian studies.

Prevention and treatment of cardiometabolic disorders by lifestyle management is the most understood and effective applications of this emerging field. The focus of this book on prediabetes, diabetes and cardiometabolic diseases is timely and will be a welcome addition to clinicians who wish to gain more knowledge and competence in the area. This book will focus on the metabolic syndrome, which is the largest non-communicable disease of our time, and lifestyle approaches that drastically reduce the risks and adverse effects of this condition. Presents a detailed review of clinical evidence and guide for implementation. Provides a toolkit to counter both the high cost of medications and the need to address metabolic disorders associated with insulin resistance early, before or simultaneous to when medications are indicated.

In the last fifty years our butterfly populations have declined by more than eighty per cent and butterflies are now facing the very real prospect of extinction. It is hard to remember the time when fields and meadows were full of these beautiful, delicate creatures - today we rarely catch a glimpse of the Wild Cherry Sphinx moths, Duke of Burgundy or the even once common Small Tortoiseshell butterflies. The High Brown Fritillary butterfly and the Stout Dart Moth have virtually disappeared. The eminent entomologist and award-winning author Josef H. Reichholf began studying butterflies in the late 1950s. He brings a lifetime of scientific experience and expertise to bear on one of the great environmental catastrophes of our time. He takes us on a journey into the wonderful world of butterflies - from the small nymphs that emerge from lakes in air bubbles to the trusting purple emperors drunk on toad poison - and immerses us in a world that we are in danger of losing forever. Step by step he explains the science behind this impending ecological disaster, and shows how it is linked to pesticides, over-fertilization and the intensive farming practices of the agribusiness. His book is a passionate plea for biodiversity and the protection of butterflies.

Please note this title is suitable for any student studying: Exam Board: AQA Level: A Level Subject: Biology First teaching: September 2015 First exams: June 2017 Written by curriculum and specification experts, this approved Student Book supports and extends students through their course. The straightforward explanations develop true subject knowledge and help students to link ideas together; an essential exam skill and one that retains their lasting interest in biology. Maths and practical skills are explored through hands-on activities and regularly reviewed throughout to ensure that they have been mastered. Ramped summary questions offer increased levels of challenge so that students can see the progress they are all making. Can be used in the classroom, while the additional guidance and tips make it easy to use independently at home.

Nobel prize-winner Paul Nurse has spent his career revealing how living cells work. In this book, he takes up the challenge of defining life in a way that every reader can understand. It is a shared journey of discovery; step by step he illuminates five great ideas that underpin biology. He traces the roots of his own curiosity and knowledge to reveal how science works, both now and in the past. Using his personal experiences, in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery. To survive the challenges that face the human race today - from climate change, to pandemics, loss of biodiversity and food security - it is vital that we all understand what life is.

From the leading author in the field, known around the world for his work and his authoritative publications, the contents of this book have been selected so as to reflect their relative importance for biopharmaceuticals. As a result, around half of the book is devoted to protein glycosylation, while the remainder is made up of other modifications, such as carboxylation, hydroxylation, sulfation, amidation and proteolytic processing. A final section addresses the latest trend of engineering the modification pattern to improve a given biopharmceutical, presenting several recent case studies of successful posttranslational engineering.
This first authoritative overview of the topic is an indispensable guide for drug developers and drug manufacturers with an interest in protein pharmaceuticals.

Systems biology is a relatively new biological study field that focuses on the systematic study of complex interactions in biological systems, thus using a new perspective (integration instead of reduction) to study them. Particularly from year 2000 onwards, the term is used widely in the biosciences, and in a variety of contexts. Systems biology is the study of the interconnected aspect of molecular, cellular, tissue, whole animal and ecological processes, and comprises mathematical and mechanistic studies of dynamical, mesoscopic, open, spatiotemporally defined, nonlinear, complex systems that are far from thermodynamic equilibrium.Containing a unique selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia of Molecular Cell Biology and Molecular Medicine, this two-volume handbook is an essential guide for students and researchers wishing to get an overview of the field.

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

This book describes in detail the various teaching strategies and assessment methods used in pharmacy education. Included in the text is both the advantages and disadvantages of each teaching and assessment method, as well as tips for effective implementation of the strategies. The text covers a plethora of teaching styles, from web based and online learning to lecture and team-based learning, and highlights some of the best practices used worldwide. This book aims to be a valuable single resource for pharmacy educators, students, and researchers. Key features One resource for the pharmacy educators, students, partitioners, researchers, policy makers and other readers with the necessary information and practical guidelines about the online pharmacy education, practice, and research. Describe and discuss the situation of the online pharmacy education, practice, and research around the world. Describe the challenges facing the online pharmacy education, practice, and research and suggest recommendations to overcome the challenges. Describe the pharmacy education teaching strategies and assessment methods. Describe the advantages and disadvantages of each teaching strategy and assessment method. Provide tips for the effective implementation of teaching strategies and assessment methods based on the best practices worldwide.

Intellectual property (IP) is a key component of the life sciences, which is becoming one of the most dynamic and innovative fields of technology today. At the same time, the relationship between IP and the life sciences is raising new public policy dilemmas. The Research Handbook on Intellectual Property and the Life Sciences comprises contributions by leading experts from academia and industry that confront current debates and controversies at the intersection of IP and the life sciences through in-depth analyses of key topics including pharmaceuticals, diagnostics and genes, plant innovations, stem cells, the role of competition law and access to medicines. The first section of this book highlights the importance of IP for medicines and pharmaceuticals, discussing topics including gene patents, and the second section deals with agricultural sector issues such as plant innovations. The third section of the book covers areas of research and development in the life sciences, such as stem cell research, and raises questions about incorporating ethical considerations into patent law. While the primary focus of the book is on Europe and the United States, the fourth section includes country-specific case studies on Australia, Brazil, China, India, Japan, Kenya, South Africa and Thailand to provide a truly international perspective. This Research Handbook is written in an accessible style that will appeal to intellectual property law scholars, practitioners and experts in the life sciences who are interested in the legal implications of IP for the life sciences. Contributors include: J. Allred, T. Avafia, C. Chiarolla, D. Degen, J.M. Golden, S. Gosh, M. Graf, J. Harrington, A. Heinemann, M.D. Janis, M. Kock, D. Matthews, C.R. McManis, A. Metzger, T. Minssen, C. Mund, P. Paranagua, A. Plomer, S. Ragavan, M. Rimmer, C. Seitz, T. Takenaka, G. Van Overwalle, D. Wachter, G. Wurtenberger, Z. Xinfeng, B. Yagi, B. Yao, H. Zech

Sample Sizes for Clinical Trials, Second Edition is a practical book that assists researchers in their estimation of the sample size for clinical trials. Throughout the book there are detailed worked examples to illustrate both how to do the calculations and how to present them to colleagues or in protocols. The book also highlights some of the pitfalls in calculations as well as the key steps that lead to the final sample size calculation. Features: Comprehensive coverage of sample size calculations, including Normal, binary, ordinal, and survival outcome data Covers superiority, equivalence, non-inferiority, bioequivalence and precision objectives for both parallel group and crossover designs Highlights how trial objectives impact the study design with respect to both the derivation of sample formulae and the size of the study Motivated with examples of real-life clinical trials showing how the calculations can be applied New edition is extended with all chapters revised, some substantially, and four completely new chapters on multiplicity, cluster trials, pilot studies, and single arm trials The book is primarily aimed at researchers and practitioners of clinical trials and biostatistics, and could be used to teach a course on sample size calculations. The importance of a sample size calculation when designing a clinical trial is highlighted in the book. It enables readers to quickly find an appropriate sample size formula, with an associated worked example, complemented by tables to assist in the calculations.

- Presents the reasons behind the decisions taken by automated algorithms - Frames eXplainable AI as a bridge between computer scientists and physicians - Emphasizes transparency in data analysis within healthcare - Covers computer vision and deep learning in tandem - Creates space to discuss human-AI relationships in future healthcare

Every city dweller is aware that we are seeing fewer stars at night due to the increasing amount of artificial lighting. But that is just the tip of the iceberg, as far as the loss of natural nocturnal darkness is concerned. Humans and animals worldwide are now suffering from the disrupted rhythm of day and night due to extreme lighting at night. In humans this can lead to illness and increased stress. Hitherto only known to experts, this book is the first to comprehensively treat the entire phenomenon of light pollution. Richly illustrated using unusual images taken from the TV documentation "The Dark Side of Light" by Anja Freyhoff and Thomas Uhlmann, this book is for anyone interested in a harmonious coexistence between humans and nature and a healthy work/life rhythm.

Collins Cambridge IGCSETM Co-ordinated Sciences Biology provides full coverage of all core and supplement Biology topics in the revised syllabus. Carefully developed features including questions, worked examples, key terms and more allow students to build firm scientific knowledge, develop practical skills and approach exams with confidence. Exam Board: Cambridge Assessment International Education For examination from 2025 Full coverage of the Biology content of the Cambridge IGCSE Co-ordinated Sciences syllabus (0654) for examination from 2025 All extended material covered and clearly differentiated Written by experienced authors who are specialists in their field Packed with questions throughout to check understanding and confirm knowledge Worked examples provide support and scaffolding Key terms and end of topic checklists allow students to check their progress Investigative tasks develop students' practical science skills Practice questions with example answers and comments help students learn how to answer questions well and hone their technique 'Science in Context' boxes deepen students' understanding of the science, how it is used and why it matters, sparking curiosity Further carefully developed features include supportive tips, knowledge checks, glossary and learning objectives to provide a clear, engaging resource for students Answers provided to support self-assessment and reflection A dedicated book for each science to keep course manageable and easy to use We are working with Cambridge Assessment International Education towards endorsement of this resource.

Preclinical Drug Development, Second Edition discusses the broad and complicated realm of preclinical drug development. Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include: Pharmacokinetics Modeling and simulation Formulation and routes of administration Toxicity evaluations The assessment of drug absorption and metabolism Interspecies scaling Lead molecule selection and optimization via profiling Screening using in silico and in vitro toxicity evaluations The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.

There has been a global rise in the incidence of chronic illnesses, which may be partially attributed to the lengthening of the average human lifespan. Functional foods and nutraceuticals have a potential role to play in the development and maintenance of health. They can assist the body in its battle against inflammation and chronic illnesses. Molecular Mechanisms of Action of Functional Foods and Nutraceuticals for Chronic Diseases addresses the effects and mechanism of functional foods in relation to chronic diseases such as obesity, cardiovascular diseases, diabetes, cancer, etc. This volume, like the companion Applications of Functional Foods and Nutraceuticals for Chronic Diseases, inspires new thought processes and a paradigm shift in research and development. Key Features: Discusses the molecular mechanism of action, the range of toxicities exerted by these food components for functional foods for addressing chronic conditions Enhances scientists and industrial personnel knowledge of functional foods and in the management of chronic diseases Presents research on the role of functional foods/nutraceuticals in preventing and treating chronic diseases through epigenetic modulation. Explores various subjects such as epigenetics, immunological, metabolic, technological and neurodenerative aspects affected by functional foods in chronic diseases The world's leading wellness centers for chronic diseases are using functional foods and nutraceuticals in their practice and discovering their useful applications, and this second of two related books is another great reference for practitioners, scientists, and clinicians in the management of chronic diseases. Contributors hail from different geographical locations around the world and have many years of research and scholarly experience in functional foods, nutraceuticals, and biology.

Understand the basics of a thriving interdisciplinary research field Microbial electrochemistry is a subfield of bioelectrochemistry which concerns interactions between microbial organisms and electrically active surfaces such as electrodes. Its growth as a subject of research has been rapid in recent years, and its technological applications are many, particularly as the race to find sustainable organic energy sourcesaccelerates. Fundamentals of Microbial Electrochemistry offers an accessible overview of this interdisciplinary subject and its potential applications. Moving smoothly from the general to the specific, it offers both fundamental principles and some of the most relevant specific examples, such as microbial fuel cells, making it the ideal choice for building a working knowledge of this exciting new field. Its solid foundation of microbial electrochemical technologies also serves as a starting point for a wide range of applied research areas. Fundamentals of Microbial Electrochemistry readers will also find: Carefully designed artistic illustrations Hands-on exercises throughout to facilitate entry into laboratory work Numerous illustrative examples and calculations designed to demonstrate and reinforce key principles Fundamentals of Microbial Electrochemistry is the perfect point of entry into this growing field for both students and researchers.

Developed for the new International A Level specification, these new resources are specifically designed for international students, with a strong focus on progression, recognition and transferable skills, allowing learning in a local context to a global standard. Recognised by universities worldwide and fully comparable to UK reformed GCE A levels. Supports a modular approach, in line with the specification. Appropriate international content puts learning in a real-world context, to a global standard, making it engaging and relevant for all learners. Reviewed by a language specialist to ensure materials are written in a clear and accessible style. The embedded transferable skills, needed for progression to higher education and employment, are signposted so students understand what skills they are developing and therefore go on to use these skills more effectively in the future. Exam practice provides opportunities to assess understanding and progress, so students can make the best progress they can.

CGP's AQA A-Level Biology Revision Question Cards are a brilliant way of putting your knowledge to the test! There are 127 cards in the pack, covering every key topic. Each one starts off with quick questions to warm you up, followed by harder questions to get your brain into top gear. Flip the card over and you'll find full answers to each question, carefully written to help you understand everything you need to know. Along the way, we've packed in plenty of diagrams and expert revision tips, and there are even questions on Practical Skills. Amazing! Matching study notes for the whole course are available in our AQA A-Level Biology Complete Revision & Practice guide (9781789080261).