Genomic and Epigenomic Biomarkers of Toxicology and Disease The latest developments in biomarker research applicable to toxicology and medicine Research on genomic and epigenomic biomarkers is developing rapidly with cutting-edge studies scattered throughout the academic literature, making the status of ongoing scientific activity in this area difficult to ascertain. Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions delivers a comprehensive and authoritative compilation of up-to-date developments in the application of genomic and epigenomic biomarkers to toxicology, disease prevention, cancer detection, therapeutics, gene therapy, and other areas. With contributions from a collection of internationally recognized investigators, this edited volume offers unique insights into current trends and future directions of research in the discussed areas. Combining state-of-the-art information on genomic and epigenomic biomarkers from a range of specialists from around the world, this monograph includes: A thorough introduction to microRNAs as non-invasive biomarkers of toxicity and chemical hazard Comprehensive explorations of extracellular vesicle-associated miRNAs as toxic biomarkers, as well as transcriptomic applications in toxicology and medicine Practical discussions of circulating miRNAs as biomarkers of metal exposure, as well as microRNAs biomarkers of malignant mesothelioma In-depth examinations of the role of noncoding RNAs in innate immune responses perturbed by environmental arsenic with a focus on microRNAs Perfect for researchers, toxicologists, risk assessors, and regulators, Genomic and Epigenomic Biomarkers of Toxicology and Disease: Clinical and Therapeutic Actions will also earn a place in the libraries of graduate students with an interest in biomarkers, toxicology, agriculture, or the environment.

Biology for the Global Citizen is an accessible, introductory learning resource for students with varying backgrounds in biology. The text encourages students to be inquisitive, sensible, and attentive, so they may seek and demand truth in all areas of life and act as informed global citizens. Through engaging material, personal applications, and active learning experiences, students develop a basic understanding of how science, and biology in particular, are pertinent to their lives. The text is comprised of a series of modules that include related laboratories. Each module explores key concepts in biology and features sections on applying science to life, quick review questions, and points of inquiry to facilitate learning. The laboratories, using computer simulations accessible through the free software tool NetLogo, reinforce the material, apply the scientific method, enhance students' quantitative literacy, employ data to support conclusions, and emphasize critical thinking and analysis. The units within the text cover essential chemistry concepts, cells, genetics, evolution and natural selection, and ecology and the environment. Developed to increase students' interest in biology and demonstrate how key concepts in the discipline have application in their everyday lives, Biology for the Global Citizen is an exemplary resource for foundational courses in science and biology.