There's no better way to prepare for OCR A AS-Level (and Year 1 of A-Level) than with this brand new and improved CGP Complete Revision & Practice book! It's bursting with straightforward study notes, helpful examples and full-colour diagrams. We've included plenty of practice questions and exam style questions (with detailed answers) plus a section of mixed (synoptic) practice testing different parts of the course. To round things off there's a section of in-depth advice on Practical Skills. There's even a free Online Edition of the whole book - just use the code printed inside the book to access it on your PC, Mac or tablet. For even more practice don't miss our OCR A AS-Level Biology Exam Practice Workbook (9781782949176).

This practice-oriented handbook surveys current knowledge on the prediction and prevention of adverse drug reactions related to off-target activity of small molecule drugs. It is unique in collating the current approaches into a single source, and includes several highly instructive case studies that may be used as guidelines on how to improve drug development projects.
With its large section on ADME-related effects, this is key knowledge for every drug developer.

With its exploration of the scientific and technological characteristics of systems exploiting molecular recognition between synthetic materials, such as polymers and nanoparticles, and biological entities, this is a truly multidisciplinary book bridging chemistry, life sciences, pharmacology and medicine.
The authors introduce innovative biomimetic chemical assemblies which constitute platforms for recruitment of cellular components or biological molecules, while also focusing on physical, chemical, and biological aspects of biomolecular recognition. The diverse applications covered include biosensors, cell adhesion, synthetic receptors, cell patterning, bioactive nanoparticles, and drug design.

The only series for MYP 4 and 5 developed in cooperation with the International Baccalaureate (IB) Develop your skills to become an inquiring learner; ensure you navigate the MYP framework with confidence using a concept-driven and assessment-focused approach presented in global contexts. - Develop conceptual understanding with key MYP concepts and related concepts at the heart of each chapter. - Learn by asking questions with a statement of inquiry in each chapter. - Prepare for every aspect of assessment using support and tasks designed by experienced educators. - Understand how to extend your learning through research projects and interdisciplinary opportunities. This title is also available in two digital formats via Dynamic Learning. Find out more by clicking on the links at the top of the page.

This first book specifically dedicated to ectoparasite drug discovery is unique in providing insights from the veterinary as well as the medical perspective, covering research from both industry and academia while paving the way for new synergies between the two research communities. Edited by a team combining 80 years of experience in academic research and industrial antiparasitic drug discovery, this volume of Drug Discovery in Infectious Diseases summarizes current knowledge in this rapidly expanding field. Comprehensive yet concise, this ready reference blends solid background information on ectoparasite biology with the very latest methods in ectoparasite drug discovery. Three major parts cover current ectoparasite control strategies and the threat of drug resistance, screening and drug evaluation, and the new isoxazoline class of ectoparasiticides. The future potential of mechanism-based approaches for repellents and parasiticides is thoroughly discussed, as are strategies for vaccines against ectoparasites, making the book ideal for parasitologists in academia as well as researchers working in the pharmaceutical industry.

Presents short topics tied to numerical or conceptual ideas, reinforced with worked examples and questions Retaining the user-friendly style of the first edition, this text is designed to eliminate the knowledge gap for those life sciences students who have not studied chemistry at an advanced level. It contains new chapters on - * Water, covering the mole concept and colloids * Gases, discussing pressure, gas laws, partial pressure, solubility of gases, and diffusion * Metals in biology, including properties, oxygen carriers, biocatalysis, charge carriers, and toxicity The authors divide their analysis of carbon compounds into two chapters. One focuses exclusively on aliphatic carbon compounds, while the other provides a greatly expanded exploration of aromatic carbon compounds, isomerism, amines and amino acids, including benzene, aromaticity, types of isomerism, and absolute configuration. With a current examination of organic and biological reactions, this instructional volume also features end-of-chapter questions and provides a solutions manual for qualified instructors. Key Features: Focuses on the particular aspects of chemistry that underpin biochemical and biomedical studies Includes new chapters on emerging topics of interest Offers a sequence of short topics with numerical or conceptual ideas supported by worked examples and questions within the text Provides a solutions manual for qualified instructors

Seit dem Erscheinen der ersten Auflage 1994 ist das Lehrbuch Hamatologie nicht mehr aus dem Ausbildungsangebot fur Medizinisch-Technische Assistenten wegzudenken. Die dritte Auflage integriert nicht nur den neuesten Stand der MTA-Ausbildung, sondern prasentiert sich mit mehr didaktischen Merkmalen und einem ubersichtlicheren Layout. Daruber hinaus wurden die folgenden Themen erweitert bzw. eingefuhrt: Hamatologische Cytogenetik Hamatologische Molekulargenetik Antikorper-Diff erenzierung Nachweis von Kalte-Agglutininen Saure-Elution Interne und externe Qualitatskontrolle in der Blutgruppenserologie.

This book was originally published in 1971. Discoveries in modern biology can radically change human life as we know it. As our understanding of living processes, such as inheritance, grows, so do the possibilities of applying these results for good and evil, such as the treatment of disease, the control of ageing, behaviour and genetic engineering. These discoveries and their implications are discussed by some of the world's leading biologists

Originally published in 1979. This reprints the revised and expanded edition of 1996. In this volume, physicists, biologists and chemists, who have been involved in some of the most exciting discoveries in modern scientific thought explore issues which have shaped modern physics and which hint at what may form the next scientific revolution. The major issues discussed are the understanding of time and space, quantum and relativity theories and recent attempts to unite them and related questions in theoretical biology.

Originally published in 1950, this book challenged the basis of our beliefs about the relation of life to matter. Already aware that chalk, limestone and coal seams are the residues of ancient life, the author suggests that this knowledge may also be applied to the rest of matter. In that case, he argues, the origin of the world was not cosmic upheaval which broke down at last into life, but organic life itself.

"Lucidly Integrates Current Activities"

Focusing on both fundamentals and recent advances, Introduction to Machine Learning and Bioinformatics presents an informative and accessible account of the ways in which these two increasingly intertwined areas relate to each other.

"Examines Connections between Machine Learning & Bioinformatics"

The book begins with a brief historical overview of the technological developments in biology. It then describes the main problems in bioinformatics and the fundamental concepts and algorithms of machine learning. After forming this foundation, the authors explore how machine learning techniques apply to bioinformatics problems, such as electron density map interpretation, biclustering, DNA sequence analysis, and tumor classification. They also include exercises at the end of some chapters and offer supplementary materials on their website.

"Explores How Machine Learning Techniques Can Help Solve Bioinformatics Problems"

Shedding light on aspects of both machine learning and bioinformatics, this text shows how the innovative tools and techniques of machine learning help extract knowledge from the deluge of information produced by today's biological experiments.

Matters of Sport is a tribute to Eric Dunning, the leading sports sociologist in the English-speaking world. This book addresses Dunning's contributions to the sociological and historical study of sport, covering key topics such as hooliganism, celebrity and gender relations.

A broad range of leading academics from Europe and North America reflect on the ways in which Dunning's work has influenced their own research and understanding of sport.

This volume was previously published as a special issue of the journal Sport in Society.

It has been said of Erasmus Darwin (1731-1802) that no one from his day to ours has ever rivalled him in his achievements in such a wide range of fields. He was a far-sighted scientific genius, fertile in theory and invention, and one of the foremost physicians of his time. His gift for friendship enabled him to recruit the members of the Lunar Society of Birmingham which is often seen as the main intellectual powerhouse of the Industrial Revolution in England. He was especially close to Franklin, Wedgwood, Boulton and Watt. Towards the end of his life he gained recognition as the leading English poet in the country, and he deeply influenced Blake, Wordsworth, Coleridge and Shelley. The most striking of Darwin's many talents was his extraordinary scientific insight in physics, chemistry, geology, meteorology and all aspects of biology -- his deepest insight being his evolutionary theory of life. Two of his books, the Zoonomia, which made him famous as the leading medical mind of the 1790s, and The Temple of Nature, a long poem, show that he believed life developed from microscopic specks in primeval seas through fishes and amphibians to 'humankind'. But he failed to convince the world about biological evolution: that was left to his grandson Charles. Erasmus was the first person to give a full description of how clouds form and of photosynthesis in plants. He was also an obsessive inventor of mechanical devices, among them a speaking machine, a copying machine and the steering technique used in modern cars. Substantial donations of Darwin family papers recently to the Cambridge University Library, including over 170 letters written by Erasmus Darwin himself, have made it possible for the author to tell much of the enthralling story of his life in Erasmus' own words. Desmond King-Hele, who is the leading authority on Erasmus Darwin having studied his life and work for three decades, is a mathematician and physicist who is an expert on space research by satellite, in particular on the Earth's gravity field and the upper atmosphere. A Fellow of the Royal Society since 1966, he has written fifteen books including a standard critical work on Shelley, Shelley: His Thought and Work, and Erasmus Darwin and the Romantic Poets; and he has edited the Letters of Erasmus Darwin.

This book uses the EM (expectation maximization) algorithm to simultaneously estimate the missing data and unknown parameter(s) associated with a data set. The parameters describe the component distributions of the mixture; the distributions may be continuous or discrete.

The editors provide a complete account of the applications, mathematical structure and statistical analysis of finite mixture distributions along with MCMC computational methods, together with a range of detailed discussions covering the applications of the methods and features chapters from the leading experts on the subject. The applications are drawn from scientific discipline, including biostatistics, computer science, ecology and finance. This area of statistics is important to a range of disciplines, and its methodology attracts interest from researchers in the fields in which it can be applied.

Endorsed by WJEC Eduqas, offering high quality support you can trust. This popular resource has been revised and updated for the 2015 WJEC and Eduqas specifications and is an essential study companion for WJEC AS & A2 Level and Eduqas Year 1 & AS and A Level Year 2 Biology students. / Written by senior examiner Marianne Izen. / Provides the essential information students need to prepare for their practical assessments and carry out the practical tasks within their AS & Year 1 and A2 & Year 2 Biology course. / Covers the 12 practical techniques required for assessment along with a description of the specified practical tasks. / Examples of interesting practical tasks throughout reinforce and illustrate the key practical skills. / Includes a clear description and explanation of the five criteria for practical assessment (CPACs) and how to achieve them. / Outlines how students should write up their experiments to enhance their skills of analysis and evaluation and to develop a logical approach to reporting practical tasks. / Practical tips and Grade boost tips provide advice on completing tasks and assessments and how to enhance performance in the practical assessments and exams. / Provides a chapter on aseptic culture and gives details on effective use of the lab book.

Agroecosystems in a Changing Climate considers the consequences of changes in the atmosphere and climate on the integrity, stability, and productivity of agroecosystems. The book adopts a novel approach by bringing together theoretical contributions from ecologists and the applied interpretations of agriculturalists. Drawing these two approaches together, the book provides the theoretical underpinning that guides scientists on what phenomena to look for, looking beyond first-order responses in the creation of sustainable agroecosystems. This unique approach provides an interpretation of ecological insights and general theory, and then relates them to agroecosystem performance.

Each section of the book combines general principles of response with an examination of the applied consequences. The authors cover the supply of resources necessary to sustain agriculture in the future and discuss the incidence of pests, weeds, diseases, and their control. They provide an understanding of how the population biology of organisms will change and the adaptations that might be possible. The book also explores plant breeding solutions and the capacity for adaptation that exists in plant populations. In addition to the full chapters, the book includes Special Example chapters that deal in more detail with specific issues.

Presenting a global perspective of climate change effects on agricultural production, Agroecosystems in a Changing Climate establishes connections between the immediate effects of change and the longer-term processes that will ultimately determine the consequences for agroecosystems and therefore the potential for adaptation.

This student-friendly CGP textbook comprehensively covers AQA AS-Level Biology and Year 1 of AQA A-Level Biology - and it's fully up-to-date for the new specifications for 2015 and beyond! It contains in-depth, accessible notes explaining every topic, supported by clear diagrams, photographs, tips and worked examples. To test students' knowledge and understanding, there are practice questions and exam-style questions throughout the book - with complete answers included. There's also detailed guidance on Maths Skills, Practical Investigations and indispensable advice for success in the final exams. An access-code for a free Online Edition is also included, allowing you to read the entire book on a PC, Mac or tablet.

A comprehensive two- volume set that describes the science and technology involved in the production and analysis of alcoholic beverages.

At the heart of all alcoholic beverages is the process of fermentation, particularly alcoholic fermentation, whereby sugars are converted to ethanol and many other minor products. The "Handbook of Alcoholic Beverages" tracks the major fermentation process, and the major chemical, physical and technical processes that accompany the production of the world's most familiar alcoholic drinks. Indigenous beverages and small-scale production are alsocovered to asignificant extent.

The overall approach is multidisciplinary, reflecting the true nature of the subject. Thus, aspects of biochemistry, biology (including microbiology), chemistry, health science, nutrition, physics and technology are all necessarily involved, but the emphasis is on chemistry in many areas of the book. Emphasis is also on more recent developments and innovations, but there is sufficient background for less experienced readers. The approach is unified, in that although different beverages are dealt with in different chapters, there is extensive cross-referencing and comparison between the subjects of each chapter.

Divided into five parts, this comprehensive two-volume work presents: INTRODUCTION, BACKGROUND AND HISTORY A simple introduction to the history and development of alcohol and some recent trends and developments,

FERMENTED BEVERAGES: BEERS, CIDERS, WINES AND RELATED DRINKS the latest innovations and aspects of the different fermentation processes used in beer, wine, cider, liquer wines, fruit wines, low-alcohol and related beverages.SPIRITS cover distillation methods and stills used in the production of whisky, cereal- and cane-based spirits, brandy, fruit spirits and liquersANALYTICAL METHODS covering the monitoring of processes in the production of alcoholic beverages, as well as sample preparation, chromatographic, spectroscopic, electrochemical, physical, sensory and organoleptic methods of analysis.

NUTRITION AND HEALTH ASPECTS RELATING TO ALCOHOLIC BEVERAGES includes a discussion on nutritional aspects, both macro- and micro-nutrients, of alcoholic beverages, their ingestion, absorption and catabolism, the health consequences of alcohol, and details of the additives and residues within the various beverages and their raw materials.

Advanced R helps you understand how R works at a fundamental level. It is designed for R programmers who want to deepen their understanding of the language, and programmers experienced in other languages who want to understand what makes R different and special. This book will teach you the foundations of R; three fundamental programming paradigms (functional, object-oriented, and metaprogramming); and powerful techniques for debugging and optimising your code. By reading this book, you will learn: The difference between an object and its name, and why the distinction is important The important vector data structures, how they fit together, and how you can pull them apart using subsetting The fine details of functions and environments The condition system, which powers messages, warnings, and errors The powerful functional programming paradigm, which can replace many for loops The three most important OO systems: S3, S4, and R6 The tidy eval toolkit for metaprogramming, which allows you to manipulate code and control evaluation Effective debugging techniques that you can deploy, regardless of how your code is run How to find and remove performance bottlenecks The second edition is a comprehensive update: New foundational chapters: "Names and values," "Control flow," and "Conditions" comprehensive coverage of object oriented programming with chapters on S3, S4, R6, and how to choose between them Much deeper coverage of metaprogramming, including the new tidy evaluation framework use of new package like rlang (http://rlang.r-lib.org), which provides a clean interface to low-level operations, and purr (http://purrr.tidyverse.org/) for functional programming Use of color in code chunks and figures Hadley Wickham is Chief Scientist at RStudio, an Adjunct Professor at Stanford University and the University of Auckland, and a member of the R Foundation. He is the lead developer of the tidyverse, a collection of R packages, including ggplot2 and dplyr, designed to support data science. He is also the author of R for Data Science (with Garrett Grolemund), R Packages, and ggplot2: Elegant Graphics for Data Analysis.

This book provides a unique introduction to the study of relationships between gender and biology, a core part of the feminist science research tradition which emerged nearly half a century ago. Lynn Hankinson Nelson presents an accessible and balanced discussion of research questions, background assumptions, methods, and hypotheses about biology and gender with which feminist scientists and science scholars critically and constructively engage. Writing from the perspective of contemporary philosophy of science, she examines the evidence for and ethical implications of biological hypotheses about gender, and discusses relevant philosophical issues including understandings of scientific objectivity, the nature of scientific reasoning, and relationships between biological research and the scientific and social contexts in which it is pursued. Clear and comprehensive, this volume addresses the engagements of feminist scientists and science scholars with a range of disciplines, including developmental and evolutionary biology, medicine, neurobiology, and primatology.

Here, the world's top experts impart their knowledge and experience, many in print for the first time. By considering developing country markets, this book is the first truly global guide to technology transfer, helping companies all around the world to avoid costly mistakes in product development and to recover investments quickly. Individual sections treat trade-related aspects of intellectual property rights, technology transfer in health and healthcare as well as in agriculture and the environment.

Economics and Biology is a collection of key essays on the relationship between economics and biology. As the limitations of the mechanistic metaphor in economics are increasingly recognized, this volume explores the potential for the use of evolutionary and other ideas from the science of biology. Topics covered include evaluations of mechanistic and biological analogies in economics in the Darwinian revolution, the use of biology in Alfred Marshall's economics, the concepts of optimisation and rationality in an evolutionary context and the inspirations that biology may offer for modern economics.

Exam Board: AQA Level: A-Level Subject: Biology First Teaching: September 2015 First Exam: Summer 2016 Create confident, literate and well-prepared students with skills-focused, topic-specific workbooks. Our Student Workbooks build students' understanding, developing the confidence and exam skills they need, whilst providing ready prepared lesson solutions. - Supplements key resources such as textbooks to adapt easily to existing schemes of work - Offers time-saving and economical lesson solutions for both specialist and non-specialist teachers - Provides flexible resource material to reinforce and apply topic understanding throughout the course, as classwork or extension tasks, or for revision - Creates opportunities for self-directed learning and assessment with answers to tasks and activities supplied online - Prepares students to meet the demands of the specification by practising exam technique and developing their literacy skills