Describes extensively the design and microfabrication of nanosensors based on nanotechnological tools. Provides a wide range of bioplatforms based on e.g., carbon nanostructures and Describes extensively a large number of application as a part of Nanomaterial based biosensors.

Real-Time Data Analytics for Large-Scale Sensor Data covers the theory and applications of hardware platforms and architectures, the development of software methods, techniques and tools, applications, governance and adoption strategies for the use of massive sensor data in real-time data analytics. It presents the leading-edge research in the field and identifies future challenges in this fledging research area. The book captures the essence of real-time IoT based solutions that require a multidisciplinary approach for catering to on-the-fly processing, including methods for high performance stream processing, adaptively streaming adjustment, uncertainty handling, latency handling, and more.

Pervasive Cardiac and Respiratory Monitoring Devices: Model-Based Design is the first book to combine biomedical instrumentation and model-based design. As the scope is limited to cardiac and respiratory devices only, this book offers more depth of information on these devices; focusing in on signals used for home monitoring and offering additional analysis of these devices. The author offers an insight into new industry and research trends, including advances in contactless monitoring of breathing and heart rate. Each chapter presents a section on current trends. As instrumentation as a field is becoming increasingly smart, basic signal processing is also discussed. Real case-studies for each modelling approach are used, primarily covering blood pressure, ECG and radar-based devices. This title is ideal for teaching and supporting learning as it is written in an accessible style and a solutions manual for the problem sets is provided. It will be useful to 4th year undergraduate students, graduate/masters/PhD students, early career researchers and professionals working on an interdisciplinary project; as it introduces the field and provides real world applications. For engineers this book solves the problem of how to assess and calibrate a medical device to ensure the data collected is trustworthy. For students, this book allows for trying concepts and circuits via simulations and learning modeling techniques. Students will learn concepts from this book and be ready to design bioinstrumentations devices based on specifications/requirements.

The only book that covers in detail a broad range of cutting-edge topics within motor rehabilitation technology

Neural engineering is a discipline that uses engineering techniques to understand, repair, replace, enhance, or treat diseases of neural systems. This book describes state-of-the-art methods within this field, from brain-computer interfaces to spinal and cortical plasticity. Touching on electrode design, signal processing, the neurophysiology of movement, robotics, and much more, this innovative book presents the latest information for readers working in biomedical engineering.

Each section of "Introduction to Neural Engineering for Motor Rehabilitation "begins with an overview of techniques before moving on to provide information on the most recent findings. Topics include: INJURIES OF THE NERVOUS SYSTEM--including diseases and injuries of the central nervous system leading to sensory-motor impairment; peripheral and spinal plasticity after nerve injuries; and motor control modules of human movement in health and diseaseSIGNAL DETECTION AND CONDITIONING--including progress in peripheral neural interfaces; multi-modal, multi-site neuronal recordings for brain research; methods for non-invasive electroencephalograph detection; wavelet denoising and conditioning of neural recordingsFUNCTION REPLACEMENT (Prostheses and Orthosis)--including an introduction to upper limb prosthetics; controlling prostheses using peripheral nerve stimulation invasive interfaces for amputees; and exoskeletal robotics for functional substitutionFUNCTION RESTORATION--including methods for movement restoration; advanced user interfaces for upper limb functional electrical stimulation; and selectivity of peripheral neural interfacesREHABILITATION THROUGH NEUROMODULATION--including brain-computer interface applied to motor recovery after brain injury; functional electrical therapy of upper extremities; and robotic assisted neurorehabilitation

"Introduction to Neural Engineering for Motor Rehabilitation" is an important textbook and reference for graduate students and researchers in the fields of biomedical and neural engineering.

Nucleic Acids as Gene Anticancer Drug Delivery Therapy highlights the most recent developments in cancer treatment using nucleic acids, nanoparticles and polymer nanoparticles for genomic nanocarriers as drug delivery, including promising opportunities for targeted and combination therapy. The development of a wide spectrum of nanoscale technologies is beginning to change the scientific landscape in terms of disease diagnosis, treatment, and prevention. This book presents the use of nanotechnology for medical applications, focusing on its use for anticancer drug delivery. Various intelligent drug delivery systems such as inorganic nanoparticles and polymer-based drug delivery are discussed. The use of smart drug delivery systems seems to be a promising approach for developing intelligent therapeutic systems for cancer immunotherapies and is discussed in detail along with nucleic acid-targeted drug delivery combination therapy for cancer. Nucleic Acids as Gene Anticancer Drug Delivery Therapy will be a useful reference for pharmaceutical scientists, pharmacologiests, and those involved in nanotechnology and cancer research.

This book is the first comprehensive overview of the emerging field of cuffless blood pressure monitoring. Increasing clinical evidence proves that longitudinal measurements of blood pressure allow for earlier detection and better management of multiple medical conditions and for superior prediction of cardiovascular events. Unfortunately, today's clinical and industry standards for blood pressure monitoring still require the inflation of a pneumatic cuff around a limb each time a measurement is taken. Over the last decades clinicians, scientists and device manufacturers have explored the feasibility of technologies that reduce or even completely eliminate the need of cuffs, initiating the era of cuffless blood pressure monitoring. Among the existing literature, this book is intended to be a practical guide to navigate across this emerging field. The chapters of the handbook have been elaborated by experts and key opinion leaders in the domain, and will guide the reader along the clinical, scientific, technical, and regulatory aspects of cuffless blood pressure monitoring.

High-Density Integrated Electrocortical Neural Interfaces provides a basic understanding, design strategies and implementation applications for electrocortical neural interfaces with a focus on integrated circuit design technologies. A wide variety of topics associated with the design and application of electrocortical neural implants are covered in this book. Written by leading experts in the field- Dr. Sohmyung Ha, Dr. Chul Kim, Dr. Patrick P. Mercier and Dr. Gert Cauwenberghs -the book discusses basic principles and practical design strategies of electrocorticography, electrode interfaces, signal acquisition, power delivery, data communication, and stimulation. In addition, an overview and critical review of the state-of-the-art research is included. These methodologies present a path towards the development of minimally invasive brain-computer interfaces capable of resolving microscale neural activity with wide-ranging coverage across the cortical surface.

This book provides an overview of biocomposite chemistry, chemical modifications, characterization and applications in biomedicine, with emphasis on recent advances in the field. Authored by experts, the chapters discuss the design, development and selection of biomedical composites for a particular therapeutic application, as well as providing insight into the regulatory and clinical aspects of biomedical composite use. While this book is primarily intended for scientists from the fields of medical, pharmaceutical, biotechnological and biomedical engineering, it is also useful as an advanced text for students and research scholars.

Classification Techniques for Medical Image Analysis and Computer Aided Diagnosis covers the most current advances on how to apply classification techniques to a wide variety of clinical applications that are appropriate for researchers and biomedical engineers in the areas of machine learning, deep learning, data analysis, data management and computer-aided diagnosis (CAD) systems design. The book covers several complex image classification problems using pattern recognition methods, including Artificial Neural Networks (ANN), Support Vector Machines (SVM), Bayesian Networks (BN) and deep learning. Further, numerous data mining techniques are discussed, as they have proven to be good classifiers for medical images.

Single-cell Omics, Volume 2: Advances in Applications provides the latest single-cell omics applications in the field of biomedicine. The advent of omics technologies have enabled us to identify the differences between cell types and subpopulations at the level of the genome, proteome, transcriptome, epigenome, and in several other fields of omics. The book is divided into two sections: the first is dedicated to biomedical applications, such as cell diagnostics, non-invasive prenatal testing (NIPT), circulating tumor cells, breast cancer, gliomas, nervous systems and autoimmune disorders, and more. The second focuses on cell omics in plants, discussing micro algal and single cell omics, and more. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and several members of biomedical field interested in understanding more about single-cell omics and its potential for research and diagnosis.

This book reviews the potential of next-generation point-of-care diagnosis in healthcare. It also discusses the printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive biomarkers detection. The book presents the development of sensory systems based on the use of nanomaterials. It examines different biosensors for medical diagnosis using surface modification strategies of transducers. It presents electrochemical concepts based on different nanobiomaterials and nanocomposites for cancer theranostics. Notably, the book examines the recent advances in wearable, cost-effective hemodynamic sensors to detect diseases at an early stage. It further explores the combination of redox cycling and electrochemical detection to develop ultrasensitive and reproducible biosensors for point-of-care testing. Finally, the book summarizes the significant challenges in the point of care diagnostics and its future opportunities in healthcare.

This book is based on the best contributions to the advancement of bioimpedance knowledge and use from the Latin American Congress series, CLABIO. Basic bioimpedance facts as well as promising and original contributions to bioimpedance theory and applications are presented, giving the reader stimulating material for reflection, decision making, and further experiments. Contributions come from a diverse international pool of experts and address topics on electrode and skin impedance modelling, tomography, spectroscopy, instrumentation, and clinical applications.

A Comprehensive Physically Based Approach to Modeling in Bioengineering and Life Sciences provides a systematic methodology to the formulation of problems in biomedical engineering and the life sciences through the adoption of mathematical models based on physical principles, such as the conservation of mass, electric charge, momentum, and energy. It then teaches how to translate the mathematical formulation into a numerical algorithm that is implementable on a computer. The book employs computational models as synthesized tools for the investigation, quantification, verification, and comparison of different conjectures or scenarios of the behavior of a given compartment of the human body under physiological and pathological conditions.

The volume is comprehensively covers emerging technologies for health care, various aspects of biomedical research towards understanding of pathophysiology of the diseases, advances in improvement in diagnostic procedures and therapeutic tools, the fundamental role of biomedical research in the development of new medicinal products

In this work, an international panel of RNAi experts critically reviews the most interesting advances in basic applied RNAi research, highlighting the applications in RNAi-based therapies and discussing the technical hurdles that remain.

Applied Human Factors in Medical Device Design describes the contents of a human factors toolbox with in-depth descriptions of both empirical and analytical methodologies. The book begins with an overview of the design control process, integrating human factors as directed by AAMI TIR 59 and experienced practice. It then explains each method, describing why each method is important, its potential impact, when it's ideal to use, and related challenges. Also discussed are other barriers, such as communication breakdowns between users and design teams. This book is an excellent reference for professionals working in human factors, design, engineering, marketing and regulation.

Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment.

This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices. This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.

This book provides a thorough overview of cutting-edge research on electronics applications relevant to industry, the environment, and society at large. It covers a broad spectrum of application domains, from automotive to space and from health to security, while devoting special attention to the use of embedded devices and sensors for imaging, communication and control. The book is based on the 2017 ApplePies Conference, held in Rome, Italy in September 2017, which brought together researchers and stakeholders to consider the most significant current trends in the field of applied electronics and to debate visions for the future. Areas addressed by the conference included information communication technology; biotechnology and biomedical imaging; space; secure, clean and efficient energy; the environment; and smart, green and integrated transport. As electronics technology continues to develop apace, constantly meeting previously unthinkable targets, further attention needs to be directed toward the electronics applications and the development of systems that facilitate human activities. This book, written by industrial and academic professionals, represents a valuable contribution in this endeavor.

Numerical PDE Analysis of Retinal Neovascularization Mathematical Model Computer Implementation in R provides a methodology for the analysis of neovascularization (formation of blood capillaries) in the retina. It describes the starting point-a system of three partial differential equations (PDEs)-that define the evolution of (1) capillary tip density, (2) blood capillary density and (3) concentration of vascular endothelial growth factor (VEGF) in the retina as a function of space (distance along the retina), x, and time, t, the three PDE dependent variables for (1), (2) and (3), and designated as u1(x, t), u2(x, t), u3(x, t), amongst other topics.

This book describes the basic physical principles of techniques to generate and ultrashort pulse lasers and applications to ultrafast spectroscopy of various materials covering chemical molecular compounds, solid-state materials, exotic novel materials including topological materials, biological molecules and bio- and synthetic polymers. It introduces non-linear optics which provides the basics of generation and measurement of pulses and application examples of ultrafast spectroscopy to solid state physics. Also it provide not only material properties but also material processing procedures. The book describes also details of the world shortest visible laser and DUV lasers developed by the author's group. It is composed of the following 12 Sections: The special features of this book is that it is written by a single author with a few collaborators in a systematic way. Hence it provides a comprehensive and systematic description of the research field of ultrashort pulse lasers and ultrafast spectroscopy. Generation of ultrashort pulses in deep ultraviolet to near infrared Generation of ultrashort pulses in terahertz Carrier envelope phase (CEP) Simple NLO processes with a few colors Multi-color involved NLO processes Multi-color ultrashort pulse generation NLO materials NLO processes in time-resolved spectroscopy Low dimension materials Conductors and superconductors Chemical reactions and material processing Photobiological reactions

Presents recent developments in sustainable materials from various engineering fields and industry applications. Emphasizes analytical strategies, computational, and simulation approaches develop innovative sustainable materials. Discusses an artificial intelligence approach, rapid prototyping, and customized production. Chapters are written by global experts. Includes case studies and research outcomes.

Encyclopedia of Tissue Engineering and Regenerative Medicine, Three Volume Set provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine.

This book reports on advanced topics in the areas of wearable robotics research and practice. It focuses on new technologies, including neural interfaces, soft wearable robots, sensors and actuators technologies, discussing industrially and medically-relevant issues, as well as legal and ethical aspects. It covers exemplary case studies highlighting challenges related to the implementation of wearable robots for different purposes, and describing advanced solutions. Based on the 5th International Symposium on Wearable Robotics, WeRob2020, and on WearRacon Europe 2020, which were both held online on October 13-16, 2020, the book addresses a large audience of academics and professionals working in for the government, in the industry, and in medical centers, as well as end-users alike. By merging together engineering, medical, ethical and industrial perspectives, it offers a multidisciplinary, timely snapshot of the field of wearable technologies.