Understanding viscoelasticity is pertinent to design applications as diverse as earplugs, gaskets, computer disks, satellite stability, medical diagnosis, injury prevention, vibration abatement, tire performance, sports, spacecraft explosions, and music. This book fits a one-semester graduate course on the properties, analysis, and uses of viscoelastic materials. Those familiar with the author s precursor book, Viscoelastic Solids, will see that this book contains many updates and expanded coverage of the materials science, causes of viscoelastic behavior, properties of materials of biological origin, and applications of viscoelastic materials. The theoretical presentation includes both transient and dynamic aspects, with emphasis on linear viscoelasticity to develop physical insight. Methods for the solution of stress analysis problems are developed and illustrated. Experimental methods for characterization of viscoelastic materials are explored in detail. Viscoelastic phenomena are described for a wide variety of materials, including viscoelastic composite materials. Applications of viscoelasticity and viscoelastic materials are illustrated with case studies."

Nanostructured Polymer Composites for Biomedical Applications addresses the challenges researchers face regarding the creation of nanostructured polymer composites that not only have superior performance and mechanical properties, but also have acceptable biological function. This book discusses current efforts to meet this challenge by discussing the multidisciplinary nature of nanostructured polymer composite biomaterials from various fields, including materials science, polymer science, biomedical engineering and biomedicine. This compilation of existing knowledge will lead to the generation of new terminology and definitions across individual disciplines. As such, this book will help researchers and engineers develop new products and devices for use in effective medical treatment.

This textbook introduces the concepts and tools that biomedical and chemical engineering students need to know in order to translate engineering problems into a numerical representation using scientific fundamentals. Modeling concepts focus on problems that are directly related to biomedical and chemical engineering. A variety of computational tools are presented, including MATLAB, Excel, Mathcad, and COMSOL, and a brief introduction to each tool is accompanied by multiple computer lab experiences. The numerical methods covered are basic linear algebra and basic statistics, and traditional methods like Newton's method, Euler Integration, and trapezoidal integration. The book presents the reader with numerous examples and worked problems, and practice problems are included at the end of each chapter.

This book offers a historical account of the development of the On-X carbon mechanical heart valve, discussing the steps involved in developing the materials, and describes how the design of the valve has evolved over the years. It explores both the scientific and corporate problems researchers have encountered over the years in the journey of making a mechanical heart valve. The chapters provide a detailed description of the design of the mechanical leaflet-based prosthetic valve, with a particular focus on blood flow characteristics. This book includes an overview of the state-of-the-art in the chemistry and physics of carbon, and compiles the advances in carbon-based technology and its applications in cardiac and thoracic surgery. This is an ideal book for bioengineers working on the chemistry and physics of carbon, and other professionals involved with cardiac and thoracic surgery.

Medical tribology can be defined as the science of tribological phenomena in the human body, both those that naturally occur in the tissues or organs and those that arise after implantation of an artificial device, while biomaterials are inert substances designed to be incorporated into living systems. Biomaterials and medical tribology brings together a collection of high quality articles and case studies focussing on new research and developments in these two important fields.
The book provides details of the different types of biomaterial available and their applications, including nanoparticles for biomedical applications, synergism effects during fiction and fretting corrosion experiments, application of biomedical-grade titanium alloys in trabecular bone and artificial joints, fatigue strengthening of an orthopaedic Ti6AI4V alloy, wear determination on retrieved metal-on-metal hip arthoplasty, natural articular joints, the importance of bearing porosity in engineering and natural lubrication, tribological characterization of human tooth enamel, and finally, liposome-based carrier systems and devices used for pulmonary drug delivery.
Biomaterials and medical tribology is an essential reference for materials scientists, engineers, and researchers in the field of medical tribology. The title also provides an overview for academics and clinicians in this area.

This book comprises a series of lectures given by celebrated Soviet neurophysiologist Nikolai Alexandrovich Bernstein in Moscow in 1925 and first published in Russian in 1926. Bernstein's groundbreaking work, which has had a significant influence on the development of neuroscience, movement studies, and other fields of study in Russia, Eastern Europe, and the West, was suppressed during Stalin's regime. At the time of its publication, Biomechanics for Instructors was a significant resource for teachers, with its descriptions of the movement of joints and degrees of freedom, illustrations of how to calculate the work capacity of muscles with bones acting as levers, the role of the central nervous system in movement, and more. Though the terminologies and methods have changed and been updated as research and technologies have progressed, the book remains a valuable introduction for those interested in Bernstein's work more generally, and to those involved in the study of biomechanics. This book is also of interest to historians and philosophers of neuroscience, as well as those involved in movement studies in both the scientific and artistic domains, and to physiotherapists and those involved in sports research and practice.

Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

The book presents the proceedings of four conferences: The 24th International Conference on Image Processing, Computer Vision, & Pattern Recognition (IPCV'20), The 6th International Conference on Health Informatics and Medical Systems (HIMS'20), The 21st International Conference on Bioinformatics & Computational Biology (BIOCOMP'20), and The 6th International Conference on Biomedical Engineering and Sciences (BIOENG'20). The conferences took place in Las Vegas, NV, USA, July 27-30, 2020, and are part of the larger 2020 World Congress in Computer Science, Computer Engineering, & Applied Computing (CSCE'20), which features 20 major tracks. Authors include academics, researchers, professionals, and students. Presents the proceedings of four conferences as part of the 2020 World Congress in Computer Science, Computer Engineering, & Applied Computing (CSCE'20); Includes the tracks on Image Processing, Computer Vision, & Pattern Recognition, Health Informatics & Medical Systems, Bioinformatics, Computational Biology & Biomedical Engineering; Features papers from IPCV'20, HIMS'20, BIOCOMP'20, and BIOENG'20.

Mineralized Collagen Bone Graft Substitutes presents a comprehensive study of biomimetic mineralized collagen, synthesized in vitro, a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the clinical use of this novel material, the book provides a complete examination, from bench to bedside. Chapters discuss natural bone and familiar biomaterials for bone repair, the preparation and safety of mineralized collagen, products made of mineralized collagen, and present clinical case studies. This book is an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry.

Statistics for Biomedical Engineers and Scientists: How to Analyze and Visualize Data provides an intuitive understanding of the concepts of basic statistics, with a focus on solving biomedical problems. Readers will learn how to understand the fundamental concepts of descriptive and inferential statistics, analyze data and choose an appropriate hypothesis test to answer a given question, compute numerical statistical measures and perform hypothesis tests 'by hand', and visualize data and perform statistical analysis using MATLAB. Practical activities and exercises are provided, making this an ideal resource for students in biomedical engineering and the biomedical sciences who are in a course on basic statistics.

This book includes research articles and expository papers on the applications of artificial intelligence and big data analytics to battle the pandemic. In the context of COVID-19, this book focuses on how big data analytic and artificial intelligence help fight COVID-19. The book is divided into four parts. The first part discusses the forecasting and visualization of the COVID-19 data. The second part describes applications of artificial intelligence in the COVID-19 diagnosis of chest X-Ray imaging. The third part discusses the insights of artificial intelligence to stop spread of COVID-19, while the last part presents deep learning and big data analytics which help fight the COVID-19.

This book provides a thorough overview of cutting-edge research on electronics applications relevant to industry, the environment, and society at large. It covers a broad spectrum of application domains, from automotive to space and from health to security, while devoting special attention to the use of embedded devices and sensors for imaging, communication and control. The book is based on the 2017 ApplePies Conference, held in Rome, Italy in September 2017, which brought together researchers and stakeholders to consider the most significant current trends in the field of applied electronics and to debate visions for the future. Areas addressed by the conference included information communication technology; biotechnology and biomedical imaging; space; secure, clean and efficient energy; the environment; and smart, green and integrated transport. As electronics technology continues to develop apace, constantly meeting previously unthinkable targets, further attention needs to be directed toward the electronics applications and the development of systems that facilitate human activities. This book, written by industrial and academic professionals, represents a valuable contribution in this endeavor.

This book offers a much-needed discussion on the targeting of biofilm-related infections. Chapters include discussions on the impact of biofilm on medical implants, industrial applications, as well as wound and tissue infections. It also offers discussions on regulatory management for industrial sectors and medical environments. Given that there continues to be a paucity of effective antimicrobial products, devices, and coatings in clinical and industrial use that effectively reduce rates of infection or biofilm-related problems, Targeting Biofilms in Translational Research, Device Development, and Industrial Sectors, offers a fresh and much-needed perspective aimed at helping create healthier controlled environments and safer devices. This comprehensive book is indispensable for industrial and academic translational researchers, device developers, and regulatory experts looking to create more effective antimicrobial products.

Features: • Provides an accessible introduction to the subject. • Up to date with the latest advances in emerging technologies and procedures. • Provides a historical overview of CT technology.

Basic Biostatistics for Medical and Biomedical Practitioners, Second Edition makes it easier to plan experiments, with an emphasis on sample size. It also shows what choices are available when simple tests are unsuitable and offers investigators an overview of how the kinds of complex tests that they won't do on their own work. The second edition presents a new, revised and enhanced version of the chapters, taking into consideration new developments and tools available, discussing topics, such as the basic aspects of statistics, continuous distributions, hypothesis testing, discrete distributions, probability in epidemiology and medical diagnosis, comparing means, regression and correlation. This book is a valuable source for students and researchers looking to expand or refresh their understanding of statistics as it applies to the biomedical and research fields. Based on the author's 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields, it is a valuable source for researchers who need to understand more about biostatistics to apply it to their work.

Foundations of Biomaterials Engineering provides readers with an introduction to biomaterials engineering. With a strong focus on the essentials of materials science, the book also examines the physiological mechanisms of defense and repair, tissue engineering and the basics of biotechnology. An introductory section covers materials, their properties, processing and engineering methods. The second section, dedicated to Biomaterials and Biocompatibility, deals with issues related to the use and application of the various classes of materials in the biomedical field, particularly within the human body, the mechanisms underlying the physiological processes of defense and repair, and the phenomenology of the interaction between the biological environment and biomaterials. The last part of the book addresses two areas of growing importance: Tissue Engineering and Biotechnology. This book is a valuable resource for researchers, students and all those looking for a comprehensive and concise introduction to biomaterials engineering.

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies.

Aimed at students, researchers, nutritionists, and developers in food technology, this research text addresses the nascent field of metabiotics. Metabiotics are products based on components of cells, metabolites, and signaling molecules released by probiotic strains, engineered to optimize host-specific physiological functions in a way that traditional probiotics cannot. This book examines the history, processes, design, classifications, and functions of metabiotics. It includes an overview of the composition and function of the gut microbiota, and discusses development of target-specific metabiotics. Further coverage includes comparisons to traditional probiotics, as well as probiotic safety and side-effects. Metabiotics: Present State, Challenges and Perspectives provides a complete history and understanding of this new field, the next phase of the probiotic industry.

This book showcases the state of the art in the field of sensors and microsystems, revealing the impressive potential of novel methodologies and technologies. It covers a broad range of aspects, including: bio-, physical and chemical sensors, actuators, micro- and nano-structured materials, mechanisms of interaction and signal transduction, polymers and biomaterials, sensor electronics and instrumentation, analytical microsystems, recognition systems and signal analysis and sensor networks as well as manufacturing technologies, environmental, food, energy and biomedical applications. The book gathers a selection of papers presented at the AISEM Regional Workshop on Sensors and Microsystems, held in Portici (Naples), Italy in February 2020.

This book offers a comprehensive and timely overview of the latest developments in the field of biomechanics and extensive knowledge of tissue structure, function, and modeling. Gathering chapters written by authoritative scientists, it reports on a range of continuum and computational models of solids, and related experimental works, for biomechanical applications. It discusses cutting-edge advances such as constitutive modeling and computational simulation of biological tissues and organs under physiological and pathological conditions, and their mechanical characterization. It covers innovative studies on arteries, heart, valvular tissue, and thrombus, brain tumor, muscle, liver, kidney, and stomach, among others. Written in honor of Professor Gerhard A. Holzapfel, the book provides specialized readers with a thorough and timely overview of different types of modeling in biomechanics, and current knowledge about biological structures and function.

This book addresses the fundamental challenges underlying bioelectronics and tissue interface for clinical investigation. Appropriate for biomedical engineers and researchers, the authors cover topics ranging from retinal implants to restore vision, implantable circuits for neural implants, and intravascular electrochemical impedance to detect unstable plaques. In addition to these chapters, the authors also document the approaches and issues of multi-scale physiological assessment and monitoring in both humans and animal models for health monitoring and biological investigations; novel biomaterials such as conductive and biodegradable polymers to be used in biomedical devices; and the optimization of wireless power transfer via inductive coupling for batteryless and wireless implantable medical devices. In addition to engineers and researchers, this book is also an ideal supplementary or reference book for a number of courses in biomedical engineering programs, such as bioinstrumentation, MEMS/BioMEMS, bioelectronics and sensors, and more. Analyzes and discusses the electrode-tissue interfaces for optimization of biomedical devices. Introduces novel biomaterials to be used in next-generation biomedical devices. Discusses high-frequency transducers for biomedical applications.

Novel Nanomaterials for Biomedical, Environmental, and Energy Applications is a comprehensive study on the cutting-edge progress in the synthesis and characterization of novel nanomaterials and their subsequent advances and uses in biomedical, environmental and energy applications. Covering novel concepts and key points of interest, this book explores the frontier applications of nanomaterials. Chapters discuss the overall progress of novel nanomaterial applications in the biomedical, environmental and energy fields, introduce the synthesis, characterization, properties and applications of novel nanomaterials, discuss biomedical applications, and cover the electrocatalytical and photothermal effects of novel nanomaterials for efficient energy applications. The book will be invaluable to academic researchers and biomedical clinicians working with nanomaterials.

An Introduction to Green Nanotechnology, Volume 28, provides students, scientists and chemical engineers with an overview of several types of nanostructures, discusses the synthesis and characterization of nanostructures, and provides applications of nanotechnology in daily life. The book offers a foundation to green nanotechnology by explaining why green nanotechnology is important. Covers biological sources in green nanotechnology, antioxidants, green nanostructures, mechanism, synthesis and characterization. The book ends with an evaluation of the risks of nanotechnology in human life and future perspectives.

Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R.

This is the second volume of the comprehensive, two-volume work on oxidative stress in lung diseases. Adopting a multidisciplinary approach, it demonstrates the cellular and molecular mechanisms associated with ROS (reactive oxygen species)-induced initiation and progression of a variety of lung diseases, such as COPD, emphysema, asthma, cystic fibrosis, occupational pulmonary diseases and pulmonary hypertension and discusses points for therapeutic intervention. The book also covers translational research and the latest research on prevention and therapeutics. Each chapter includes in-depth insights into the mechanisms associated with lung diseases and into identifying targets for drug development. Bridging the gap between fundamental and translational research, and examining applications in the biomedical and pharmaceutical industry, it is a thought- provoking read for basic and applied scientists engaged in biomedical research.