Bone Response to Dental Implant Materials examines the oral environment and the challenges associated with dental biomaterials. Understanding different in vivo and in vitro responses is essential for engineers to successfully design and tailor implant materials which will withstand the different challenges of this unique environment. This comprehensive book reviews the fundamentals of bone responses in a variety of implant materials and presents strategies to tailor and control them.

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention.

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics.

Biocompatibility of Dental Biomaterials details and examines the fundamentals of biocompatibililty, also including strategies to combat it. As biomaterials used in the mouth are subject to different problems than those associated with the general in vivo environment, this book examines these challenges, presenting the latest research and forward-thinking strategies.

The main goal of the present book is to deal with the role of nanobiotechnology in skin, soft tissue and bone infections since it is difficult to treat the infections due to the development of resistance in them against existing antibiotics. The present interdisciplinary book is very useful for a diverse group of readers including nanotechnologists, medical microbiologists, dermatologists, osteologists, biotechnologists, bioengineers. Nanotechnology in Skin, Soft-Tissue, and Bone Infections is divided into four sections: Section I- includes role of nanotechnology in skin infections such as atopic dermatitis, and nanomaterials for combating infections caused by bacteria and fungi. Section II- incorporates how nanotechnology can be used for soft-tissue infections such as diabetic foot ulcer and other wound infections; Section III- discusses about the nanomaterials in artificial scaffolds bone engineering and bone infections caused by bacteria and fungi; and also about the toxicity issues generated by the nanomaterials in general and nanoparticles in particular. The readers will be immensely enriched by the knowledge of new and emerging nanobiotechnologies in a variety of platforms.

Bioelectronics is emerging as a new area of research where electronics can selectively detect, record, and monitor physiological signals. This is a rapidly expanding area of medical research, that relies heavily on multidisciplinary technology development and cutting-edge research in chemical, biological, engineering, and physical science. This book provides extensive information on the (i) fundamental concepts of bioelectronics, (ii) materials for the developments of bioelectronics such as implantable electronics, self-powered devices, bioelectronic sensors, flexible bioelectronics, etc, and (iii) an overview of the trends and gathering of the latest bioelectronic progress. This book will broaden our knowledge about newer technologies and processes used in bioelectronics.

The rise in living standards increases the expectation of people in almost every field. At the forefront is health. Over the past few centuries, there have been major developments in healthcare. Medical device technology and developments in artificial intelligence (AI) are among the most important ones. The improving technology and our ability to harness the technology effectively by means such as AI have led to unprecedented advances, resulting in early diagnosis of diseases. AI algorithms enable the fast and early evaluation of images from medical devices to maximize the benefits. While developments in the field of AI were quickly adapted to the field of health, in some cases this contributed to the formation of innovative artificial intelligence algorithms. Today, the most effective artificial intelligence method is accepted as deep learning. Convolutional neural network (CNN) architectures are deep learning algorithms used for image processing. This book contains applications of CNN methods. The content is quite extensive, including the application of different CNN methods to various medical image processing problems. Readers will be able to analyze the effects of CNN methods presented in the book in medical applications.

The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience.Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.The chapter "Aggregation-Induced Emission In Electrochemiluminescence: Advances and Perspectives" is available open access under a CC BY 4.0 License via link.springer.com.

Chitosan Based Biomaterials: Tissue Engineering and Therapeutics, Volume 2, provides the latest information on chitosan, a natural polymer derived from the marine material chitin. Chitosan displays unique properties, most notably biocompatibility and biodegradability. It can also be easily tuned to modify its structure or properties, making chitosan an excellent candidate as a biomaterial. Consequently, chitosan is being developed for many biomedical functions, ranging from tissue engineering and implant coatings to drug and gene delivery. This book provides readers with a full coverage of the applications of chitosan-based biomaterials.

Advanced Porous Biomaterials for Drug Delivery Applications probes cutting-edge progress in the application of advanced porous biomaterials in drug delivery fields. These biomaterials offer promise in improving upon the design, cost, and creation of potent novel drug delivery systems. The book focuses on two categories: nature engineered and synthetic advanced porous biomaterials, with a wide range of low-cost porous biomaterial-based systems that have been used for the delivery of diverse drugs through in vitro/in vivo approaches. Details how advanced porous biomaterial-assisted systems improve essential properties in drug delivery applications Explains how advanced porous biomaterials systems are being used and explored to improve overall performances of drug delivery systems in mitigating a variety of diseases Emphasizes major applications in drug delivery such as controlled release, cancer therapy, and targeted delivery, and with focus on oral, topical, and transdermal applications Focuses on both naturally available and synthetic low-cost advanced porous biomaterials and their role in enhancing important parameters in drug delivery applications Accessible to readers with bio and non-bio backgrounds This book is an ideal reference for academics, researchers, and industry professionals in the interdisciplinary fields of biomedicine and biomedical engineering, pharmaceuticals, materials science, and chemistry.

This book characterizes how to design and synthesize nanomaterials of an organic and mineral nature. The book also discusses the visualization of developed nanomaterials and their bio-applications, as well as describes the biomedical effects and environmental impact of nanomaterials. This is an ideal book for students studying biomedicine or the life sciences, as well as researchers and professionals in medicine, environmental protection, biotechnology, agriculture, and the food industry. More specifically, this book addresses the important nanomaterials and nanobiotechnologies that are used in those fields in biomedicine and life sciences.

Medical imaging is one of the heaviest funded biomedical engineering research areas. The second edition of Pattern Recognition and Signal Analysis in Medical Imaging brings sharp focus to the development of integrated systems for use in the clinical sector, enabling both imaging and the automatic assessment of the resultant data. Since the first edition, there has been tremendous development of new, powerful technologies for detecting, storing, transmitting, analyzing, and displaying medical images. Computer-aided analytical techniques, coupled with a continuing need to derive more information from medical images, has led to a growing application of digital processing techniques in cancer detection as well as elsewhere in medicine. This book is an essential tool for students and professionals, compiling and explaining proven and cutting-edge methods in pattern recognition for medical imaging.

Microbiorobotics is a new engineering discipline that inherently involves a multidisciplinary approach (mechanical engineering, cellular biology, mathematical modeling, control systems, synthetic biology, etc). Building robotics system in the micro scale is an engineering task that has resulted in many important applications, ranging from micromanufacturing techniques to cellular manipulation. However, it is also a very challenging engineering task. One of the reasons is because many engineering ideas and principles that are used in larger scales do not scale well to the micro-scale. For example, locomotion principles in a fluid do not function in the same way, and the use of rotational motors is impractical because of the difficulty of building of the required components.

This book provides a concise overview of VR systems and their cybersickness effects, giving a description of possible reasons and existing solutions to reduce or avoid them. Moreover, the book explores the impact that understanding how efficiently our brains are producing a coherent and rich representation of the perceived outside world would have on helping VR technics to be more efficient and friendly to use. Getting Rid of Cybersickness will help readers to understand the underlying technics and social stakes involved, from engineering design to autonomous vehicle motion sickness to video games, with the hope of providing an insight of VR sickness induced by the emerging immersive technologies. This book will therefore be of interest to academics, researchers and designers within the field of VR, as well as industrial users of VR and driving simulators.

This book explores the design of ultra wideband (UWB) technology for wireless body-area networks (WBAN). The authors describe a novel implementation of WBAN sensor nodes that use UWB for data transmission and narrow band for data reception, enabling low power sensor nodes, with high data rate capability. The discussion also includes power efficient, medium access control (MAC) protocol design for UWB based WBAN applications and the authors present a MAC protocol in which a guaranteed delivery mechanism is utilized to transfer data with high priority. Readers will also benefit from this book s feasibility analysis of the UWB technology for human implant applications through the study of electromagnetic and thermal power absorption of human tissue that is exposed to UWB signals. "

This book looks at the growing segment of Internet of Things technology (IoT) known as Internet of Medical Things (IoMT), an automated system that aids in bridging the gap between isolated and rural communities and the critical healthcare services that are available in more populated and urban areas. Many technological aspects of IoMT are still being researched and developed, with the objective of minimizing the cost and improving the performance of the overall healthcare system. This book focuses on innovative IoMT methods and solutions being developed for use in the application of healthcare services, including post-surgery care, virtual home assistance, smart real-time patient monitoring, implantable sensors and cameras, and diagnosis and treatment planning. It also examines critical issues around the technology, such as security vulnerabilities, IoMT machine learning approaches, and medical data compression for lossless data transmission and archiving. Internet of Medical Things is a valuable reference for researchers, students, and postgraduates working in biomedical, electronics, and communications engineering, as well as practicing healthcare professionals.

This book aims at exposing its readers to some of the most significant advances in assistive technologies. Assistive technologies develop devices to assist vulnerable people, including elderly people, people with cognitive disabilities such as memory problems or dementia, and people with functional disabilities such as those needing support in toileting, moving around, eating, bathing, dressing, grooming, and taking personal care. The ever-increasing life expectancy and world population, along with the emergence of new diseases and the regrettable continuation of armed conflicts, press for development and availability of assistive technologies that offer people in need the opportunity to live secure and controlled lives with more active participation in society and at a reduced assistive cost. This task can be accomplished only with more advanced devices than traditional-powered wheelchairs or eating/drinking devices, including prosthetics, exoskeletons, visual and hearing aids, cognitive aids, and devices enhanced with artificial intelligence. The book consists of an editorial note and an additional twelve (12) chapters, all of which have been written by authors who work on the corresponding chapter theme and are recognized for their significant research contributions. In more detail, the chapters in the book are organized into four parts, namely (i) Advances in Assistive Technologies in Healthcare, (ii) Advances in Assistive Technologies in Medical Diagnosis, (iii) Advances in Assistive Technologies in Mobility and Navigation, and (iv) Advances in Privacy and Explainability in Assistive Technologies. This research book is directed towards professors, researchers, scientists, engineers, and students in assistive technologies. It is also directed towards readers who come from other disciplines and is interested in becoming versed in some of the most recent assistive technologies. An extensive list of bibliographic references at the end of each chapter guides its readers to probe further into the application areas of interest to them.

Provides strong and accessible theoretical bases to swarm intelligence algorithms, from particle optimization to bioinspired and meta-heuristic algorithms Presents emerging meta-heuristic algorithms and applications Provides overviews on Python and R based computing libraries for swarm intelligence and meta-heuristic algorithms Presenting real-world applications, especially on Industry, Medicine and Biology.

Provides strong and accessible theoretical bases to swarm intelligence algorithms, from particle optimization to bioinspired and meta-heuristic algorithms Presents emerging meta-heuristic algorithms and applications Provides overviews on Python and R based computing libraries for swarm intelligence and meta-heuristic algorithms Presenting real-world applications, especially on Industry, Medicine and Biology.

The articles in this book review hybrid experimental-computational methods applied to soft tissues which have been developed by worldwide specialists in the field. People developing computational models of soft tissues and organs will find solutions for calibrating the material parameters of their models; people performing tests on soft tissues will learn what to extract from the data and how to use these data for their models and people worried about the complexity of the biomechanical behavior of soft tissues will find relevant approaches to address this complexity.

Bacterial Nanocellulose: From Biotechnology to Bio-Economy presents an overview on the current and future applications of bacterial nanocellulose, perspectives on the ecology and economics of its production, and a brief historic overview of BNC related companies.

Biostatistics for Practitioners: An Interpretative Guide for Medicine and Biology deals with several aspects of statistics that are indispensable for researchers and students across the biomedical sciences. The book features a step-by-step approach, focusing on standard statistical tests, as well as discussions of the most common errors. The book is based on the author's 40+ years of teaching statistics to medical fellows and biomedical researchers across a wide range of fields.

This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.

This book provides an in-depth introduction to the newest technologies for designing wireless power transfer systems for medical applications. The authors present a systematic classification of the various types of wireless power transfer, with a focus on inductive power coupling. Readers will learn to overcome many challenges faced in the design a wirelessly powered implant, such as power transfer efficiency, power stability, and the size of power antennas and circuits. This book focuses exclusively on medical applications of the technology and a batteryless capsule endoscopy system and other, real wirelessly powered systems are used as examples of the techniques described.