Davidson's Assessment in Medicine is a collection of 1250 best-of-five multiple choice questions, arranged to correspond with the chapters of the Twenty-third Edition of Davidson's Principles and Practice. The questions follow the style used in many international undergraduate and early postgraduate exams. For each question the answers are accompanied by a short piece of remediation/ feedback with references back to the main textbook for further information. This book is an excellent broad assessment text and forms a highly useful complement to the main textbook. It will help students increase the efficiency with which they acquire the factual knowledge necessary for both passing examinations and good medical practice. Although written to accompany Davidson's Principles and Practice of Medicine, this book can be used alongside any clinical medicine textbook. 1250 best-of-five multiple choice questions with detailed answers and remediation feedback. Closely linked to the world-renowned Davidson's Principles and Practice of Medicine textbook.

In Advances in Medicine and Biology. Volume 127, the authors discuss Parkinson's disease (PD), a neurological disorder characterized by the death of dopaminergic neurons in the substantia nigra pars compacta and reduced dopamine levels in the striatum. Currently, there are few pharmacological treatments for PD and although Levodopa has frequently been used, it is not a viable treatment option for all patients. Thus, this book presents experimental evidence supporting the claim that endocannabinoid signaling may represent a promising therapeutic target for PD, inducing a reduction in neurodegeneration with minimal psychotropic effects. Subsequently, it presents findings that free-hydroxyproline observed in a physiological system must be resulted from a degradation of protein molecules. Variations in free-hydroxyproline concentrations in the plasma and white muscle of fishes, with genetic differences in growth rates and with different feedings, could indicate differences in protein degradation rates for tissue remodeling and growth. Since the synthesis of the connective tissue framework of muscle is a rate-limiting step in muscle growth, the concentrations of white muscle free-hydroxyproline could be reliable for growth studies, as its levels are correlated with fish specific growth rates (SGR) and feed efficiency. Next, the authors analyze the results of umbilical hernia repair using Ventralex (R) Hernia Patch, a bilayer prosthesis. Preoperative characteristics, surgical procedure details, postoperative complications and recurrence rate were studied. An overview of the most up-to-date findings on the association of NGF with development of schizophrenia is presented, based on literature data as well as the authors own findings. The contributions of other research groups are provided and discussed in the context of prominent existing hypothesis of psychiatric disorder development. Afterwards, hernias are discussed as one of the most common reasons a primary care patient may need referral for surgical intervention. The emergence of next-generation prosthesis seeks to achieve the best possible integration into the tissues, improving their performance on all interfaces and avoiding complications. The authors exhibit a retrospective cohort study to assess the impact of 6-hour versus 4-hour HD sessions in end-stage renal disease (ESRD) patients treated with three times per week, daytime, in-center HD. Using data from a cohort of forty-three, stable chronic ESRD patients, the authors compared twenty-one patients undergoing 6-hour HD sessions with twenty-two patients on conventional 4-hour HD sessions. The following chapter begins with an introduction to collagen and the function of Hyp in the collagen molecule, followed by a description of sources of various Hyp fractions in tissues and body fluids. The effects of different toxins on various Hyp fractions in the serum and tissues are also discussed. Then, soy isoflavones or soy derivatives (supplements containing S-equol) are recommended for relieving vasomotor symptoms. The evidences for standardized cohosh preparations are effective and are also be recommended. This book also discusses DNA damage repair, a very important biological process commonly associated with human health and diseases, because a detailed elucidation of DNA repair mechanism is essential for a better understanding of health and disease. Afterwards, the current information on collagen PTMs and their alteration under different pathological conditions are examined. It has been reported that collagen undergoes polyubiquitination in response to S-adenosyl-L-methionine. The polyubiquitination inhibits Collagen processing leading to decreased collagen secretion in hepatic stellate cells (HSCs). In closing, a critical review about the impact of changes in lifestyle and diet supplementation with natural phytochemicals on cancer statistics is given. This review highlights the new advances in understanding the anticancer activity of flavonoids based on its ability to damage DNA in cancer cells.

In Advances in Medicine and Biology. Volume 128, the authors provide evidence that several families of GPCRs dynamically modulate microglial phenotypes and provide evidence that aberrations in G-protein coupled receptors-mediated signaling are prime contributors to a loss of homeostatic microglia states. A comprehensive landscape on the physiological conditions already known to be important for dendritic cell (DC) differentiation is included. Specifically: presenting stages of development of bone marrow stem cells; comparing the ontogeny of DCs in mice and humans; debating the differences between conventional DCs versus plasmacytoid DCs; highlighting that Langerhans cells (LCs) have different origins; discussing factors that may modulate the development of DC subsets; and emphasizing ontogenetic properties of DCs that make them different from monocytes and macrophages. Next, the authors review ex vivo and in vitro studies about the effects of human soluble fibrinogen molecule on blood components behavior and its effects at physiological and pathophysiological conditions, as well as in vitro studies conducted in experimental animal models. The tacrolimus (TAC) metabolism is reviewed in a separate study which proposes the TAC metabolism rate (C/D ratio) as a novel tool to assist physicians in risk stratification to individualize therapy in patients after (renal) transplantation. Continuing, the book postulates that modulation of nitric oxide (NO) concentrations at the maternal-fetal interface is relevant for maintaining early gestation due to failures in vascular adaptations. NO regulates vascular tone, angiogenesis, and cellular aggregation and adhesion, which are important functions in establishing and maintaining normal pregnancy. This book also presents the research and development of a collaborative, social-networked approach to train elementary and middle-school students so that the students can be aware of their bad sitting posture and timely improve it. Results show that the proposed approach and the developed posture training tools were very effective in improving teens posture.

The English Speaker's Guide to Doctors & Hospitals in Mexico is a comprehensive, up-to-date directory of English-speaking medical practitioners, specialists and hospitals in Mexico and recommended by trusted resources. The guide is organized by location and type of practitioner or specialist, which makes it quick and easy to find the medical care providers you need while living in or visiting Mexico. The guide covers over 90 different locations across Mexico, including all the major towns and cities, and many of the secondary towns and small settlements near them. Where English-speaking specialists are available, you will find listings for dermatologists, endocrinologists, fertility specialists, gastroenterologists, gynecologists, hematologists, internists, neurologists, obstetricians, oncologists, orthopedists, pathologists, pediatricians, plastic surgeons, psychiatrists, psychologists, radiologists, surgeons, traumatologists, urologists, etc. Written by award-winning science and medicine writer Monica Rix Paxson, author of The English Speaker's Guide to Medical Care in Mexico and researcher and author Luis Felipe Garcia Perez.