Relevant to students, academics and practitioners across the globe, this original volume highlights contemporary issues associated with assisted reproduction and embryology and critically analyzes the law surrounding human reproduction in the light of case law and technological developments since the Human Fertilisation and Embryology Act (HFE Act) Act was passed in 1990.

Tackling issues from an interdisciplinary perspective, the authors identify and evaluate areas that have provoked intense public and academic debate as well as those where further or renewed regulation is needed. Focusing primarily on the legal and ethical issues involved in regulating this area in the UK, which is at the forefront of developing legislation in this area, this book has international relevance as many countries have used the UK as a model for their own legislation.

This text is suitable for a broad range of readers, including legal academics, law students and practitioners interested in the areas of medical/healthcare law and ethics, bioethics and moral philosophy, family law, sociology and reproductive medicine and genetics.

In spite of the fact that almost eighty percent of all IVF cycles are unsuccessful, the dominant representations of the technology are of its success. Based on extensive interviews with women and couples who have undergone IVF unsuccessfully and who have since stopped treatment, and taking an overtly feminist approach, the book explores the ways in which IVF failure is experienced and accounted for. The book argues that IVF failure and the end of treatment have to be carefully managed over time in order to construct the self as 'normal' in the profoundly gendered context of reproductive normativity. Treatment failure is identified in the book not only as a central, but largely excluded, aspect of the experience of IVF, but also of a proliferating range of new, more controversial reproductive and genetic technologies.

A few gray hairs and a couple of wrinkles are often the first visible signs of aging on our bodies. For most of us, however, aging remains largely a mystery. We can only wonder why we have to age and what casualty of age hovers nearby. Written in everyday language, The Clock of Ages takes us on a tour of the aging human body--all from a research scientist's point of view. From the deliberate creation of organisms that live three times their natural span to the isolation of genes that may allow humans to do the same, The Clock of Ages also examines the latest discoveries in geriatric genetics. Sprinkled throughout the pages are descriptions of the aging of many historical figures, such as Florence Nightingale, Jane Austen, Billy the Kid, Napoleon, and Casanova. These stories underscore the common bond of senescence that unites us all. The Clock of Ages tells us why.

The early environment in which we grow up has profound, long lasting, and often irreversible consequences for us throughout our lives. Stresses due to undernutrition in early childhood can mean that in adulthood individuals are smaller, more prone to disease, and have a shorter life expectancy than those with normal diets. Disease and poor living conditions in infancy and childhood also have serious implications in adulthood. While environmental effects on human growth and development are well documented, the long term consequences due to processes taking place at the early stages of growth and development have only recently become a focus of intense study. In this volume, leading researchers in nutrition, epidemiology, human biology, anthropology and physiology bring together a uniquely accessible source of information on this fascinating topic.

This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors - both internationally respected anthropologists and new voices - demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals' and lay people's intimate encounters with policy. Authors look closely at core policy debates in the history of global maternal health across six different continents, including: Women's use of misoprostol for abortion in Burkina Faso The place of traditional birth attendants in global maternal health Donor-driven maternal health programs in Tanzania Efforts to integrate qualitative evidence in WHO maternal and child health policy-making Anthropologies of Global Maternal and Reproductive Health will engage readers interested in critical conversations about global health policy today. The broad range of foci makes it a valuable resource for teaching in medical anthropology, anthropology of reproduction, and interdisciplinary global health programs. The book will also find readership amongst critical public health scholars, health policy and systems researchers, and global public health practitioners.

This open access edited book brings together new research on the mechanisms by which maternal and reproductive health policies are formed and implemented in diverse locales around the world, from global policy spaces to sites of practice. The authors - both internationally respected anthropologists and new voices - demonstrate the value of ethnography and the utility of reproduction as a lens through which to generate rich insights into professionals' and lay people's intimate encounters with policy. Authors look closely at core policy debates in the history of global maternal health across six different continents, including: Women's use of misoprostol for abortion in Burkina Faso The place of traditional birth attendants in global maternal health Donor-driven maternal health programs in Tanzania Efforts to integrate qualitative evidence in WHO maternal and child health policy-making Anthropologies of Global Maternal and Reproductive Health will engage readers interested in critical conversations about global health policy today. The broad range of foci makes it a valuable resource for teaching in medical anthropology, anthropology of reproduction, and interdisciplinary global health programs. The book will also find readership amongst critical public health scholars, health policy and systems researchers, and global public health practitioners.

This volume, and its companion volume on the oocyte, provide an authoritative and wide-ranging account of the gametes, and their reproductive role and function in humans. Acknowledged authorities from around the world provide a detailed and timely account of the spermatozoon. The volume starts with an evolutionary perspective before focusing on the molecular and cellular biology of the sperm cell, and its structure and function. The development and maturation of sperm are described, as is their movement and transport in the male and female genital tract. Practical issues such as sperm storage and assisted contraception are fully covered. The causes of male infertility are also an important theme. The volume concludes with a thought-provoking chapter on ethical considerations. The volume will be an essential source of information for all clinicians and scientists with an interest in human reproduction.

This volume, and its companion volume on the spermatozoon, provide an authoritative and wide ranging account of the gametes and their reproductive role and function in humans. Acknowledged authorities from around the world contribute a detailed and timely account of the oocyte. The volume starts with an evolutionary perspective before focusing on the molecular and cellular biology of the oocyte and its structure and function. The development and maturation of the oocyte is fully dealt with to include the endocrine and paracrine regulation of ovarian function. Practical issues such as oocyte storage and ovarian stimulation are also fully covered. The causes of female infertility are also an important theme. The volume concludes with a thought provoking chapter on ethical considerations. The volume will be an essential source of information for all clinicians and scientists with an interest in human reproduction.

Within 10 chapters this book addresses the whole gamut of questions that may arise in the context of pregnancy resulting from assisted reproduction. Incidence of abortion, extrauterine pregnancy or chromosomal abnormalities, pregnancy complications, problems regarding mode of delivery and the health status of children at birth are covered as well as the further development of the children and the social structure of the families. Topics such as follow-up of families in lesbian relationships and following gamete donations are also discussed.

"Will the future confront us with human GMOs? Greely provocatively declares yes, and, while clearly explaining the science, spells out the ethical, political, and practical ramifications."-Paul Berg, Nobel Laureate and recipient of the National Medal of Science Within twenty, maybe forty, years most people in developed countries will stop having sex for the purpose of reproduction. Instead, prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth. And it will be safe, lawful, and free. In this work of prophetic scholarship, Henry T. Greely explains the revolutionary biological technologies that make this future a seeming inevitability and sets out the deep ethical and legal challenges humanity faces as a result. "Readers looking for a more in-depth analysis of human genome modifications and reproductive technologies and their legal and ethical implications should strongly consider picking up Greely's The End of Sex and the Future of Human Reproduction... [It has] the potential to empower readers to make informed decisions about the implementation of advancements in genetics technologies." -Dov Greenbaum, Science "[Greely] provides an extraordinarily sophisticated analysis of the practical, political, legal, and ethical implications of the new world of human reproduction. His book is a model of highly informed, rigorous, thought-provoking speculation about an immensely important topic." -Glenn C. Altschuler, Psychology Today

Reproduction plays a huge part in many people's lives, but often little is understood about the biological processes involved and the larger impact of reproductive choices. This book offers an accessible, comprehensive introduction to this fascinating subject. Irina Pollard takes a unique, interdisciplinary perspective, describing in detail the biology of human reproduction, but also covering in depth the impact of procreational behavior on human social structures, the environment, and health. This compelling and authoritative account is the first to draw together in a single volume these two disparate yet intimately connected strands of the story of human reproduction. The book covers fertility and infertility, sexual behavior and pheromones, sperm creation, maternal physiology during pregnancy, fetal development, the biology of breast feeding, and the impact of parental behavior on the physiology of the newborn, as well as population dynamics, artificial control of fertility, the AIDS epidemic, the effects of nutrition and exercise on reproductive behavior, and the causes of birth defects, including abuse of substances such as nicotine, alcohol, and caffeine. This book is an ideal text for undergraduate and graduate students studying biology, medicine, anthropology, human ecology, population dynamics, and public health. It is also an engrossing and enlightening source of information for a wide range of general readers including prospective parents, pregnant mothers, teenagers, and anyone wishing a concise, up-to-date review of human reproductive biology.

Reproduction plays a huge part in many people's lives, but often little is understood about the biological processes involved and the larger impact of reproductive choices. This book offers an accessible, comprehensive introduction to this fascinating subject. Irina Pollard takes a unique, interdisciplinary perspective, describing in detail the biology of human reproduction, but also covering in depth the impact of procreational behavior on human social structures, the environment, and health. This compelling and authoritative account is the first to draw together in a single volume these two disparate yet intimately connected strands of the story of human reproduction. The book covers fertility and infertility, sexual behavior and pheromones, sperm creation, maternal physiology during pregnancy, fetal development, the biology of breast feeding, and the impact of parental behavior on the physiology of the newborn, as well as population dynamics, artificial control of fertility, the AIDS epidemic, the effects of nutrition and exercise on reproductive behavior, and the causes of birth defects, including abuse of substances such as nicotine, alcohol, and caffeine. This book is an ideal text for undergraduate and graduate students studying biology, medicine, anthropology, human ecology, population dynamics, and public health. It is also an engrossing and enlightening source of information for a wide range of general readers including prospective parents, pregnant mothers, teenagers, and anyone wishing a concise, up-to-date review of human reproductive biology.

Despite France and Belgium sharing and interacting constantly with similar culinary tastes, music and pop culture, access to Assisted Reproductive Technologies are strikingly different. Discrimination written into French law acutely contrasts with non-discriminatory access to ART in Belgium. The contributors of this volume are social scientists from France, Belgium, England and the United States, representing different disciplines: law, political science, philosophy, sociology and anthropology. Each author has attempted, through the prism of their specialties, to demonstrate and analyse how and why this striking difference in access to ART exists.

This concise 1993 volume proposes a standardized approach to the investigation of infertility. The volume provides clear guidelines and a logical sequence of steps which will quickly lead the clinician or physician to an accurate diagnosis of the underlying cause of infertility. This standardized approach to the management of infertility will lead to more efficient, systematic and economic care for the infertile couple. The diagnostic charts, which may be photocopied, provide an unambiguous route to diagnosis of the underlying cause of infertility, whilst the text fully explains and describes the essential clinical tests. The volume summarizes the results gained from the study of more than 10,000 infertile couples, who were investigated as part of the WHO's programme to counter the widespread personal distress caused by infertility. It is hoped that the standardized approach presented here will go some way towards countering this major problem.

What is expected of 21st Century egg and sperm donors, and how does being a donor impact on men and women's own personal lives and relationships? How do donors navigate connections and relationships created by donation? What do these connections mean to them, and to the people around them -their partners, parents, siblings and children? Donor conception is becoming increasingly widespread and since the new millennium, we have witnessed a dramatic shift in the way that donor conception is regulated and practiced in many jurisdictions around the world. In the past, donor conception has often been a family secret and donors were, almost by definition, anonymous. Now, 'openness' is seen as the ideal and donors can expect to be traced or contacted by those born from their donations. But what does this shift mean for donors, and their families? This path-breaking book draws on in-depth interviews with donors, their kin and fertility counsellors, and addresses these questions by analysing how understandings of donation are shaped by the regulatory, cultural and relational contexts in which they are formed. The authors also discuss what donation stories can tell us about contemporary understandings of connectedness, time and morality in the context of reproduction and family life, and consider how reproductive 'openness' might be done differently.

This volume describes from an interdisciplinary perspective human motor development using longitudinal study methods. The biological basis of motor development is discussed, looking at mechanisms of embryonic growth and fetal development. Fetal movement patterns and developmental processes and adaptations that continue throughout childhood are also treated. Chapters cover the mechanisms that underlie the development of posture, goal-directed behavior, movement patterns for communication and the acquisition of skills, such as tool use and writing. The book also considers how the developmental process can go wrong. Possible risk factors for abnormal motor development are discussed and the adaptive processes that accompany motor deficiencies in childhood and later life are also described.

A cutting-edge analysis of the global issues surrounding modern reproductive technologies Advances in assisted reproductive technologies have sparked global policy debates since the birth of the first so-called "test tube baby" in 1978. Today, mitochondrial replacement therapies represent the most recent advancement in assisted reproductive technologies, allowing some women with mitochondrial diseases to birth babies without those diseases. In the past decade, mitochondrial replacement therapies have captured public sentiment, reigniting debates around social views of reproductive rights and the appropriate legal and political response. Reproduction Reborn guides readers through the history and science of mitochondrial replacement therapies and the various attempts to control them. Leading experts from medicine, genetics, ethics, law, and policy explore the influence of public debate on the evolving shape of these technologies and their subsequent regulation. They highlight case studies from both developed and developing countries across the globe, including recent legislation in Australia and China. They further identify the ethical, legal, and societal norms that need to be addressed by policymakers and communities as more and more people seek to gain access to these treatments. Given the importance of reproduction in family life and cultural identity, clinicians and policymakers must understand how regulatory regimes around mitochondrial replacement therapies have evolved to illuminate the processes and challenges of governing reproduction in a fast-moving world. Informative and global in scope, Reproduction Reborn explores how advancements in assisted reproductive technologies challenge core values surrounding the rights and responsibilities of modern-day family units.

The health of a population is most accurately reflected in the rate of growth of its children. This theme, prevalent in this book, underlies the analysis and presentation of what is by far the largest compilation of growth data ever assembled in one source. The first edition, published in 1976, included all known reliable recent results on height, weight, skinfolds, and other body measurements from all parts of the globe. In this edition, numerous subsequent measurements taken between 1976 and 1988 have been included, as well as the results of a large number of new studies made on rate of maturation as evinced by bone age and pubertal development stages. Many sections of the book dwell on disentangling the effects of the environment and heredity on growth, and attempt to answer the question of whether one universal standard suffices for all peoples of the world or whether different populations (such as races or nations) should each have their own optimal growth standards.

The health of a population is most accurately reflected in the rate of growth of its children. It is this theme which underlies the analysis and presentation of what is by far the largest compilation of growth data ever assembled. The first edition, published in 1976, included all known reliable recent results on height, weight, skinfolds and other body measurements from all parts of the globe. In this edition, the very numerous measurements taken between 1976 and 1988 have been included as well as the results of the large number of new studies made on rate of maturation as evinced by bone age and pubertal development stages. Many sections of the book dwell on disentangling the effects of the environment and heredity on growth, and thus answer the question of whether one universal standard suffices for all peoples of the world, or whether different populations (such as races or nations) should each have their own optimal growth standards. Written by practical people with experience of the problems in developing countries, this book explains in simple terms the different sorts of growth surveys, how to set about making them, and which sort to choose. All who are professionally concerned with child health should read it.

A geneticist tells the stories of men, women, and children whose genes have shaped their lives in unexpected ways.

It was while listening to a colleague tell the parents of a newborn girl that their daughter was going to die that a lifelong interest in genetic medicine was sparked in Dr Edwin Kirk. Warmth and gentleness tempered a direct, sure manner - this was the medicine he wanted to practise, where the most advanced science and the most deeply human meet. Twenty-five years later, Dr Kirk works both with patients and in the lab, and he spearheads a campaign that will change the way we think about having babies. His experience is without parallel, but it is his humour and insight that make all the difference.

Find out why Dr Kirk found himself among hundreds of people, each with a glass of poison in front of them - and how you might perform the same experiment yourself (without the poison). Learn how the realisation that a young boy wasn't short ended up saving the life of his mother - and how Angelina Jolie has saved the lives of many more. Sit in the room with Dr Kirk and his patients as they navigate the world of heartbreaking uncertainties, tantalising possibilities, and thorny questions of morality. In genetics, it is the particularities of an individual's history that matter, and here, in clear and considerate writing, those individual stories are given voice.

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Keeping active, moving well, and stretching regularly are all important in living a long, healthy, and happy life. In Stay Young with Yoga, yoga teacher Nicola Jane Hobbs shows you how to stay flexible, energised and pain-free in your 40s, 50s, 60s and beyond. Whether you want to move better, get stronger, ease aches and pains, or simply feel fitter and healthier, Nicola guides you through over 70 simple poses and 20 easy-to-practise sequences, with variations and modifications so you can choose poses and sequences that suit you. With routines designed to fit in with your lifestyle, including morning sequences, desk stretches, de-stress routines, sequences to practice after gardening, housework, and in front of the TV, as well as routines for pain-free movement, workouts for strength and fitness, and routines to support your other hobbies like golf, tennis, and dancing, Stay Young with Yoga will give you the tools to get stronger, fitter and healthier whatever your age.

Investigations on anatomical specimens have demonstrated that the subchondral mineralization does indeed show regular distribution patterns from which conclusions about the mechanical situation within an individual joint may be drawn. Since radiographical densitometry and histological methods are only available for determining the adaptive reaction of the bone to the mechanical situation in a joint after death, the information obtained applies only to an end situation and tells us nothing about the development of the changes with time. Furthermore, investigations carried out on human specimens by radiographical densitometry mostly apply to samples of a particular age, since such specimens can be acquired only from departments of pathology, forensic medicine or anatomy.

Male infertility is a clinician-orientied book aimed at the clinician dealing with the infertile couple because rational, effective management is only possible if the couple are considered together. The aim of the work is to provide advice to the clinician and to give reference to the underlying science. This will not only enable clinicians to understand the underlying science but will also give scientists an insight to clinical work. This blend of science and clinical work is reflected in the contributors who are experts drawn from both fields.