The most common abnormal growth of the female reproductive system, fibroids, are thought to affect the majority of women at some point during their reproductive years. This text from leading fibroid experts looks at the latest evidence on how the problem impinges on reproduction and the most up-to-date management and treatment options available to help patients with fibroids hoping to conceive. Print versions of this book also include access to the eBook version with links to procedural videos.

Molecular Biology of Placental Development and Disease, the latest volume in the Progress in Molecular Biology and Translational Science series, focuses on placental development and disease.

This new edition provides a much-needed reference book to accommodate emerging and expanding knowledge in fertility preservation, the rapidly growing field of reproductive medicine associated with advances in oncology. Written by a team of world-leading experts in the field and comprehensive in its scope, the book covers the full range of techniques and scientific concepts in detail. It opens with an introduction to fertility preservation in both cancer and non-cancer patients, followed by fertility preservation strategies in males and females, including medical/surgical procedures, ART, cryopreservation and transplantation of ovarian tissue, and in-vitro follicle culture. Concluding chapters address new technologies, as well as ethical, legal and religious issues. The book has been thoroughly updated, includes additional contributors, and now provides greater focus on practical and clinically relevant issues. Richly illustrated throughout, this is a key resource for clinicians specializing in reproductive medicine, gynecology, oncology, hematology, endocrinology and infertility.

The second edition of this popular text systematically addresses all aspects of treatment of infertility using Chinese medicine. Clinically focused and with a new easy-to-navigate design, the book begins by covering all the essential fundamentals you will need to understand and treat infertility, before going on to look at what Chinese medicine offers in the way of treatment for functional infertility in men and women, gynecological disorders which contribute to infertility and relevant lifestyle factors. Jane Lyttleton importantly devotes a large part of the book to discussing ways in which Chinese medicine and Western medicine might work together to overcome infertility, and details the increased experience over the past decade in working with IVF patients and their specialists. Leaps forward have also been made in the understanding of conditions such as Polycystic ovarian syndrome and immune infertility.  New Features ·      Greatly expanded section on the place of Chinese medicine and IVF in treatment of infertility ·      New information on Polycystic ovarian disease and immune infertility and how Chinese medicine approaches their treatment ·      Updated and balanced advice on pre-conception care ·      Clinically focused, with easy-to-navigate design

Introduced in Phnom Penh around 1990, at the twilight of socialism and after two decades of conflict and upheaval, ultrasound took root in humanitarian and then privatized medicine. Services have since multiplied, promising diagnostic information and better prenatal and general health care. In Fixing the Image Jenna Grant draws on years of ethnographic and archival research to theorize the force and appeal of medical imaging in the urban landscape of Phnom Penh. Set within long genealogies of technology as tool of postcolonial modernity, and vision as central to skilled diagnosis in medicine and Theravada Buddhism, ultrasound offers stabilizing knowledge and elicits desire and pleasure, particularly for pregnant women. Grant offers the concept of "fixing"-which invokes repair, stabilization, and a dose of something to which one is addicted-to illuminate how ultrasound is entangled with practices of care and neglect across different domains. Fixing the Image thus provides a method for studying technological practice in terms of specific materialities and capacities of technologies-in this case, image production and the permeability of the body-illuminating how images are a material form of engagement between patients, between patients and their doctors, and between patients and their bodies.

This extensive book provides an up-to-date overview by leading international authorities, spanning the disciplines of neuroscience, psychology, ophthalmology, optometry, and paediatrics, of normal and pathological infant visual development. It covers the development of retinal receptors; infant sensitivity to detail, colour, contrast, and movement; binocularity, eye movements, and refraction, and cognitive processing. Childrens' visual deficits, including amblyopia and cataract are covered.

Fertility Awareness is key to understanding sexual and reproductive health at all life stages. It can be used to either plan or avoid pregnancy. Fertility Awareness Methods (FAMs) are highly effective when motivated couples are taught by trained practitioners. These methods are in demand for ecological, medical, cultural, religious and moral reasons. The ability to control fertility naturally is a lifestyle choice. The Complete Guide to Fertility Awareness provides the science and methodology suitable for health professionals and a general audience. It covers reproductive physiology and the fertility indicators: temperature, cervical secretions and cycle length calculations. It explores ways to optimise conception and to manage conception delays. Case studies and self-assessment exercises are included throughout. The book addresses the scientific credibility of new technologies including fertility apps, home test kits, monitors and devices. The Complete Guide to Fertility Awareness offers: evidence-based information for general practitioners, practice nurses, school nurses, midwives, sexual health doctors and nurses a unique perspective on subfertility for gynaecologists and fertility nurses an authoritative source of reference for medical, nursing and midwifery students a straightforward and practical reference for new and experienced FAM users the core text for the FertilityUK Advanced Skills Course in Fertility Awareness

Our technologies are progressively developing into algorithmic devices that seamlessly interface with digital personhood. This text discusses the ways in which technology is increasingly becoming a part of personhood and the resulting ethical issues. It extends upon the framework for a brain-based cyberpsychology outlined by the author's earlier book Cyberpsychology and the Brain: The Interaction of Neuroscience and Affective Computing (Cambridge, 2017). Using this framework, Thomas D. Parsons investigates the ethical issues involved in cyberpsychology research and praxes, which emerge in algorithmically coupled people and technologies. The ethical implications of these ideas are important as we consider the cognitive enhancements that can be afforded by our technologies. If people are intimately linked to their technologies, then removing or damaging the technology could be tantamount to a personal attack. On the other hand, algorithmic devices may threaten autonomy and privacy. This book reviews these and other issues.

Although there are far more opportunities for LGBTQ people to become parents than there were before the 1990s, attention to the reproductive challenges LGBTQ families face has not kept pace. Reproductive Losses considers LGBTQ people's experiences with miscarriage, stillbirth, failed adoptions, infertility, and sterility. Drawing on Craven's training as a feminist anthropologist and her experiences as a queer parent who has experienced loss, Reproductive Losses includes detailed stories drawn from over fifty interviews with LGBTQ people (including those who carried pregnancies, non-gestational and adoptive parents, and families from a broad range of racial/ethnic, socio-economic, and religious backgrounds) to consider how they experience loss, grief, and mourning. The book includes productive suggestions and personal narratives of resiliency, commemorative strategies, and communal support, while also acknowledging the adversity many LGBTQ people face as they attempt to form families and the heteronormativity of support resources for those who have experienced reproductive loss. This is essential reading for scholars and professionals interested in LGBTQ health and family, and for individuals in LGBTQ communities who have experienced loss and those who support them. See additional material on the companion website: www.lgbtqreproductiveloss.org/

Spermatogenesis is a tightly regulated cellular renovation and differentiation process. It consists of self-renewal and differentiation of spermatogonial stem cells (SSCs), spermatocytic meiosis and spermiogenesis; each of these processes is essential to the continuous, successful production of male gametes. During spermiogenesis, haploid spermatids undergo extensive cellular, molecular and morphological changes, including acrosome biogenesis, flagellum development, cytoplasmic reorganization and chromatin condensation. These changes ultimately result in mature spermatozoa with an acrosome-covered head and motile tail. In this book, Chapter One summarizes the progress that has been made in understanding the molecular mechanisms underlying acrosome biogenesis, and the authors discuss the potential directions of future investigations of this process. Chapter Two briefly addresses the basics of spermatogenesis and the synthesis of ncRNAs, and then the authors discuss the recent progress in understanding of the functions of miRNAs, endo-siRNAs, piRNAs and lncRNAs in the regulation of spermatogenesis. Chapter Three provides a review of the current literature on testicular immunoregulation and its underlying mechanisms, along with its effect on testicular functions.

The effects of the bone morphogenetic proteins (BMPs) family on bone formation are well documented, but the transforming growth factor (TGF)-beta ( ) isoforms are much less studied. The product of 20 years of study, Induction of Bone Formation in Primates: The Transforming Growth Factor- 3 sums up editor Ugo Ripamonti's research into the osteogenic activity of the three mammalian TGF- isoforms, particularly in primates. It explores how the mammalian TGF- isoforms have the potential to shed light on the apparent redundancy of bone induction signaling. The book unearths the profound and important bone inductive activity of the TGF- 3 isoform. It includes accounts of extensive research in non-human primates from craniofacial tissue regeneration, heterotopic tissue induction, and chapters on periodontal tissue regeneration and synergistic induction of bone formation. It also discusses the future clinical role of the TGF- isoform, including in human studies. This book contributes to the fascinating history of BMP and TGF- research at the intersection of molecular biology, tissue induction, bone regeneration, and craniofacial surgery. It provides a revolutionary awakening to new possibilities in skeletal reconstruction, tissue engineering, and molecular and cellular biology.

The comprehensive and authoritative guide to clinical reproductive science The field of clinical reproductive science continues to evolve; this important resource offers the basics of reproductive biology as well as the most recent advance in clinical embryology. The author - a noted expert in the field - focuses on the discipline and covers all aspects of this field. The text explores causes of male and female infertility and includes information on patient consultation and assessment, gamete retrieval and preparation, embryo culture, embryo transfer and cryopreservation. Comprehensive in scope, the text contains an introduction to the field of clinical reproductive science and a review of assisted reproductive technology. The author includes information on a wide range of topics such as gonadal development, the regulation of meiotic cell cycle, the biology of sperm and spermatogenesis, in vitro culture, embryo transfer techniques, fundamentals of fertilisation, oocyte activation and much more. This important resource: Offers an accessible guide to the most current research and techniques to the science of clinical reproduction Covers the fundamental elements of reproductive science Includes information on male and the female reproductive basics - everything from sexual differentiation to foetal development and parturition Explores the long-term health of children conceived through IVF Contains the newest developments in assisted reproductive technology Clinical Reproductive Science is a valuable reference written for professionals in academia, research and clinical professionals working in the field of reproductive science, clinical embryology and reproductive medicine.

This unique source of reference provides a comprehensive guide to the adverse side-effects of many commonly prescribed drugs on fertility and sexual health. More than 150 drugs are listed in this compilation, and the evidence linking them with infertility and sexual dysfunction is carefully reviewed. The volume is designed to provide a rapid source of reference to alert doctors and pharmacists to these hazardous side-effects. The volume also includes an introductory account of the reproductive process and a review of the mechanisms by which these drugs can interfere or inhibit reproduction. Another important theme of the volume is the effect of social and recreational drugs and environmental agents on reproductive health.

This book looks at the major changes that have occurred in the theory and practice of speech therapy for children with developmental speech disorders. It looks at current issues and their clinical implications, but the overall aim of the book is to set clinical practice firmly in a theoretical framework. While it is therefore essentially a practical book for practitioners, it also engages in the academic investigation of the nature of the different types of developmental speech disorders and their consequences for the children. This discussion provides the framework in which to consider clinical management and specific clinical techniques.

A recurrent theme throughout each chapter is the impact of linguistics upon our understanding and management of children' s problems in learning to pronounce. There is no doubt that the linguistic revolution in speech and language pathology has produced an entirely new perspective on these disorders by identifying the phonological dimension of speech development.

Of equal importance is the expansion of knowledge about children' s language development. Much more information is now available about phonological development in terms of what the developmental changes are and when they occur. This information is valuable in assessment and diagnosis. The book also includes a number of competing theories explaining how children develop their pronunciation patterns. These theories provide the premises upon which to establish a principled theory of therapy.

To reflect these issues and their clinical implications the book is divided into three sections. The first section explores the framework within which to discuss developmental speech disorders.The second section covers three specific types of pathological conditions with which developmental speech disorders are associated. The third section examines the problems of children who have no evident major disabling condition and yet they experience severe difficulties learning to pronounce and subsequently, more often than not, learning to read and write.

In Neurosis and Human Growth, Dr. Horney discusses the neurotic process as a special form of the human development, the antithesis of healthy growth. She unfolds the different stages of this situation, describing neurotic claims, the tyranny or inner dictates and the neurotic's solutions for relieving the tensions of conflict in such emotional attitudes as domination, self-effacement, dependency, or resignation. Throughout, she outlines with penetrating insight the forces that work for and against the person's realization of his or her potentialities. First Published in 1950. Routledge is an imprint of Taylor & Francis, an informa company.

"The Atlas of Chick Development, Third Edition," a classic work covering all major event of chick development, is extensively updated with new and more detailed photographs, enlargements showing regions of special-interest and complexity, and new illustrations. The revised text and expanded illustrative material describe the intricate changes that take place during development, together with accounts of recent experimental and molecular research that has transformed our understanding of morphogenesis.

These wide-ranging updates make this book an essential resource for developmental biologists, geneticists, molecular biologists, poultry scientists, biochemists, immunologists, and other life scientists who use the chick embryo as their research model. Individuals joining this burgeoning area, ignited by the increased insight into events surrounding organ and tissue differentiation, will find this a valuable tool to help grow a basic knowledge of morphogenesis.
Remains the established standard the only book providing a comprehensive description of chick development from fertilization to hatching
Contains more than 750 photographs and illustrations, including 410 labelled histological sections and 85 new high-quality plates, showing the major anatomical events from the earliest stages to 13 days of incubation
Includes more than 200 labelled and detailed scanning electron micrographs, showing various tissues in great detail
Leads the reader to important reviews on aspects of this rapidly moving field, along with extensive and updated references"

Research documents that rural elders are poorer, live in less adequate housing, and have far fewer health and service options available to them than their urban counterparts, yet there is a critical lack of current and detailed information on the problems facing rural elders and on the professional practices that serve this population. This text fills this gap by introducing readers to rural areas and their residents and discussing the issues, programs, and policies designed to meet their needs. Through a multidisciplinary lens, it examines and defines specific competencies required for successful work with older adults and their families in these communities.

The text presents a research-driven, competency-based approach for the health and human service professionals who work with older rural residents. It discusses both the problems facing older adults and their families and evidence-based solutions regarding policy and best practices. Key issues examined include health and wellness, transportation, housing, long-term care, income, employment, and retirement, along with the needs of special populations (ethnic minorities, immigrants, and the LGBT population). Case examples reinforce an interdisciplinary model that addresses practice with rural elders that encompasses professional competencies, values and ethics, and the roles of a spectrum of health and human service professionals. The text also examines current policies affecting health and social services to rural elders and recommendations for policy change to build an effective health and human service workforce in rural communities. Links to Podcast interviews with scholars and respected professionals working in the field and "Spotlight" excerpts from the text reinforce information. In addition, the text provides discussion questions, PowerPoint slides, a test question bank, and suggested activities and exercises.

Key Features: Fills a vacuum regarding information on health and social services for rural elders Provides current and comprehensive knowledge about issues besetting this population and programs and policies designed to meet their needs Examines and defines specific competencies required for effective health and social services Based on a research-driven, competency-based, interdisciplinary approach to policy and best practice Includes links to Podcast interviews with scholars and respected professionals in the field

"Aging: Oxidative Stress and Dietary Antioxidants" bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in aging and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this.

Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging.
Nutritionists can apply information related to mitochondrial oxidative stress in one disease to diet-related strategies in another unrelated disease Dietitians can prescribe new foods or diets containing anti-oxidants for conditions resistant to conventional pharmacological treatments Dietitians, after learning about the basic biology of oxidative stress, will be able to suggest new treatments to their multidisciplinary teamsNutritionists and dietitians will gain an understanding of cell signaling and be able to suggest new preventative or therapeutic strategies with anti-oxidant rich foods

"Original, important, moving, witty and exquisitely-written. WHAT a feat." - BERNARDINE EVARISTO "Incredible... beautiful and funny and humane." - EMILIE PINE "Pristine poetry and prose." KATHERINE MAY, AUTHOR OF WINTERING "Babies who are this small, he says, have a good chance of survival. Small is not good for babies. It is not whimsical or cute or the cause of admiration. It is the first time it occurs to us that they might not survive. Babies die from smallness." Claire Lynch knew that having children with her wife would be complicated but she could never have anticipated the extent to which her life would be redrawn by the process. This dazzling debut begins with the smallest of life's substances, the microscopic cells subdividing in a petri dish in a fertility treatment centre. She moves through her story in incremental yet ever growing steps, from the fingernail-sized pregnancy test result screen which bears two affirmative lines to the premature arrival of her children who have to wear scale-model oxygen masks in their life-saving incubators. Devastatingly poignant and profoundly observant - and funny against the odds - Claire considers whether it is our smallness that makes our lives so big.

Since the late nineteenth century, medicine has sought to foster the birth of healthy children by attending to the bodies of pregnant women, through what we have come to call prenatal care. Women, and not their unborn children, were the initial focus of that medical attention, but prenatal diagnosis in its present form, which couples scrutiny of the fetus with the option to terminate pregnancy, came into being in the early 1970s. Tangled Diagnoses examines the multiple consequences of the widespread diffusion of this medical innovation. Prenatal testing, Ilana Löwy argues, has become mainly a risk-management technology—the goal of which is to prevent inborn impairments, ideally through the development of efficient therapies but in practice mainly through the prevention of the birth of children with such impairments. Using scholarship, interviews, and direct observation in France and Brazil of two groups of professionals who play an especially important role in the production of knowledge about fetal development—fetopathologists and clinical geneticists—to expose the real-life dilemmas prenatal testing creates, this book will be of interest to anyone concerned with the sociopolitical conditions of biomedical innovation, the politics of women’s bodies, disability, and the ethics of modern medicine.

Male factor infertility is receiving greater emphasis in IVF programs. This book reviews the scientific evidence for various medical, environmental and lifestyle factors that can affect male fertility, such as chromosome abnormalities, age, anti-sperm antibodies and endocrine disruptors. Part of a four-book series on improving IVF success, this volume subsequently explores a range of treatments and strategies to improve sperm quality, including FSH treatment and antioxidants. It also discusses methods to prevent male infertility from childhood through to adulthood. Concise, practical and evidence-based - and with insights from global experts in the field - this text will enable gynecologists, urologists and andrologists to make evidence-based decisions that can influence the success rate of fertilization in subsequent IVF cycles.

This new volume of "Current Topics in Developmental Biology" covers the area of gametogenesis, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells.
Covers the area of gametogenesisInternational board of authorsProvides a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells

The Developing Human: Clinically Oriented Embryology, by Drs. Keith L. Moore, T.V.N. Persaud, and Mark G. Torchia, delivers the world's most complete, visually rich, and clinically oriented coverage of this complex subject. Written by some of the world's most famous anatomists, it presents week-by-week and stage-by-stage views of how fetal organs and systems develop, why and when birth defects occur, and what roles the placenta and fetal membranes play in development. You can also access the complete contents online at www.studentconsult.com, along with 17 remarkable animations, downloadable illustrations, additional review questions and answers, and more.

A Common Thread is a collection of sixteen brave and honest accounts of fertility issues and miscarriage. Each journey is unique; yet each contributor shares truthfully from their heart the highs and lows they have been through; how their journey has affected their faith and how God has brought them through. Although the physical, emotional and mental toll can be unbearable for those who find themselves facing these battles, there is hope. Within this book you will read the stories of those who have experienced successful IVF, failed IVF, multiple miscarriages, miscarriage after having children, adoption, miracle births, and those who have never been able to have children. Although we all experience the journey differently, we all share 'a common thread' of understanding. You are not alone.