This book presents important and recent research on testosterone which is a steroid hormone from the androgen group. Testosterone is primarily secreted in the testes of males and the ovaries of females although small amounts are secreted by the adrenal glands. It is the principal male sex hormone and an anabolic steroid. In both males and females, it plays key roles in health and well-being. Examples include enhanced libido, energy, immune function, and protection against osteoporosis. On average, the adult male body produces about twenty times the amount of testosterone that an adult female's body does.

The health of a population is most accurately reflected in the rate of growth of its children. This theme, prevalent in this book, underlies the analysis and presentation of what is by far the largest compilation of growth data ever assembled in one source. The first edition, published in 1976, included all known reliable recent results on height, weight, skinfolds, and other body measurements from all parts of the globe. In this edition, numerous subsequent measurements taken between 1976 and 1988 have been included, as well as the results of a large number of new studies made on rate of maturation as evinced by bone age and pubertal development stages. Many sections of the book dwell on disentangling the effects of the environment and heredity on growth, and attempt to answer the question of whether one universal standard suffices for all peoples of the world or whether different populations (such as races or nations) should each have their own optimal growth standards.

This book is a practical guide to the detection, diagnosis and treatment of infertility. Beginning with an overview of human reproduction, the importance of accurate history taking and examination, and general preconception evaluation, the following chapters discuss the different investigational methods in the assessment of female infertility. The final sections examine male infertility and the role of semen analysis in understanding the potential of fertility. Genetic, environmental and behavioural risk factors are also covered. This comprehensive text is enhanced by clinical images, diagrams and tables. Key Points Practical guide to detection, diagnosis and treatment of infertility Covers assessment of both female and male infertility Covers genetic, environmental and behavioural risk factors Enhanced by clinical images, diagrams and tables

Entirely revised and updated and with a foreword by John Guillebaud, this is the much anticipated new edition of an invaluable, practical guide which has become an established reference for all those working in reproductive health. As in the previous edition, all forms of contraceptives are covered in detail, with guidance on prescribing, possible complications and advantages/disadvantages. The book continues to provide evidence-based clinical guidance for family-planning providers. Since the last edition was published, family planning and reproductive health has become much more closely linked with genito-urinary (GU) medicine.Reflecting this, the specialty has become known as sexual and reproductive healthcare. Among the many developments since the last edition are new types of progestogen-only pill and a profusion of new strategies and guidelines. This fifth edition is a complete update on developments in the field, integrating the new contraceptives, strategies and guidelines within family planning and reproductive healthcare.

Brown Bodies, White Babies focuses on the practice of cross-racial gestational surrogacy, in which a woman - through in-vitro fertilization using the sperm and egg of intended parents or donors - carries a pregnancy for intended parents of a different race. Focusing on the racial differences between parents and surrogates, this book is interested in how reproductive technologies intersect with race, particularly when brown bodies produce white babies. While the potential of reproductive technologies is far from pre-determined, the ways in which these technologies are currently deployed often serve the interests of dominant groups, through the creation of white, middle-class, heteronormative families. Laura Harrison, providing an important understanding of the work of women of color as surrogates, connects this labor to the history of racialized reproduction in the United States. Cross-racial surrogacy is one end of a continuum in which dominant groups rely on the reproductive potential of nonwhite women, whose own reproductive desires have been historically thwarted and even demonized. Brown Bodies, White Babies provides am interdisciplinary analysis that includes legal cases of contested surrogacy, historical examples of surrogacy as a form of racialized reproductive labor, the role of genetics in the assisted reproduction industry, and the recent turn toward reproductive tourism. Joining the ongoing feminist debates surrounding reproduction, motherhood, race, and the body, Brown Bodies, White Babies ultimately critiques the new potentials for parenthood that put the very contours of kinship into question.

A critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF Each year, more and more Americans travel out of the country seeking low cost medical treatments abroad, including fertility treatments such as in vitro fertilization (IVF). As the lower middle classes of the United States have been priced out of an expensive privatized "baby business," the Czech Republic has emerged as a central hub of fertility tourism, offering a plentitude of blonde-haired, blue-eyed egg donors at a fraction of the price. Fertility Holidays presents a critical analysis of white, working class North Americans' motivations and experiences when traveling to Central Europe for donor egg IVF. Within this diaspora, patients become consumers, urged on by the representation of a white Europe and an empathetic health care system, which seems nonexistent at home. As the volume traces these American fertility journeys halfway around the world, it uncovers layers of contradiction embedded in global reproductive medicine. Speier reveals the extent to which reproductive travel heightens the hope ingrained in reproductive technologies, especially when the procedures are framed as "holidays." The pitch of combining a vacation with their treatment promises couples a stress-free IVF cycle; yet, in truth, they may become tangled in fraught situations as they endure an emotionally wrought cycle of IVF in a strange place. Offering an intimate, first-hand account of North Americans' journeys to the Czech Republic for IVF, Fertility Holidays exposes reproductive travel as a form of consumption which is motivated by complex layers of desire for white babies, a European vacation, better health care, and technological success.

Has the college experience of women been an influence on the number of children desired and the number and spacing of their children? Do women come to college with their attitudes and values in this regard already formed? This study of 15,000 women, freshmen and seniors in 45 American colleges and universities, both secular and nonsecular, attempts to answer this question and to determine how such characteristics as religious preference, career intentions, and the number of children in her own family influence a woman's fertility values. Attention is paid to an earlier finding that Catholic college graduates have higher fertility than Catholic high school graduates, although higher education is usually associated with lower fertility. Originally published in 1967. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

The bestselling author returns with his biggest book yet in which he teaches us the secret to living a happier life: get rid of as many expectations as possible-of ourselves, our future, our relationships, our career and our family. Expectations are the secret software, running on the hardware of our minds, controlling our emotions, decisions, and actions. How? Think about your life. How much of the sadness you feel derives from what you think should have happened-than with what actually happened? Think about your career. How much of the discontent you feel comes from your belief about where you'd be at this point-than with the progress you've actually made? Think about your relationships. How much of your dissatisfaction with friends, family, significant others, or spouses has to do with your unspoken presumptions-than with the people themselves? Having so many expectations is distorting your perspective, decreasing your happiness and disrupting your joy. You can live a life of true freedom, greater peace and less stress: release as many expectations as possible. This, DeVon Franklin argues, is the secret to a better life now. In a culture obsessed with more, Live Free is a bold counterintuitive book that can start a cultural revolution, Franklin contends. Everyone struggles with unnecessary expectations. But once you learn to let go of them, you can set the stage for the life you've always wanted.

Manual of Ovulation Induction and Ovarian Stimulation Protocols encompasses all aspects of ovulation induction and current stimulation protocols in detail. This detailed text provides the reader with a reliable overview of the principles involved and the management required for ovulation induction in the treatment of infertility. This book is comprised of 68 chapters which cover the tailoring of ovarian stimulation regimens to a patient's medical history and previous response to treatment. Both the clinical and sonographic findings in evaluating ovulatory function and dysfunction are discussed in detail. Methods for monitoring folliculogenesis, which in turn allows the ART specialist to accurately predict the number, as well as the timing of the high quality of oocyte retrieval, are discussed in detail. The book features discussion on basic and clinical research evidence, which is accumulating to propose the future use of recombinant FSH and LH in order to achieve controlled ovarian stimulation. The inclusion of the most current research in this second edition makes Manual of Ovulation Induction and Ovarian Stimulation Protocols a valuable book for gynaecologists, infertility specialists, and healthcare professionals dealing with IVF. Key Points Includes current research and future implications 60+ full colour images and illustrations New edition. First published 2005

This book presents a comprehensive review of the morphology and function of chromosomes in elderly people. The wide range of topics includes cyclical chromosome properties, mutations, repair, progressive chromosome heterochromatinisation with increasing age, roles of nucleolar organiser regions, sister chromatid exchanges, homologue relationships, heterochromatin regions and other chromosomal features in very old age. This ground-breaking book focuses on heterochromatinisation as a key determinant of the genetic apparatus function during senescence and an area to seek life-prolonging interventions. The book illustrates and updates progress in the field of cytogenetics of ageing.

Understand the rapidly growing complexities of obstetric hematology and high-risk pregnancy management, with experts in the field. Now in its second edition, this comprehensive and essential guide focuses on providing the best support for patients and clinical staff, to prevent serious complications in pregnancy and the post-partum period for both mother and baby. Wide-ranging and detailed, the guide offers discussions on basic principles of best care, through to tackling lesser-known hematological conditions, such as cytopenias and hemoglobinopathies. Updated with color illustrations, cutting-edge research, accurate blood film reproductions, and practical case studies, the revised edition places invaluable advice into everyday context. This unique resource is essential reading for trainees and practitioners in obstetrics, anesthesia, and hematology, as well as midwives, nurses, and laboratory staff. Clarifying difficult procedures for disease prevention, the guide ensures safety when the stakes are high. Reflecting current evidence-based guidelines, the updated volume is key to improving pregnancy outcomes worldwide.

In this, our Second Edition of Reproduction in Mammals, we are responding to numerous requests for a more up-to-date and rather more detailed treatment of the subject. The First Edition was accorded an excellent reception, but the first five books were written ten years ago and inevitably there have been advances on many fronts since then. As before, the manner of presentation is intended to make the subject matter interesting to read and readily comprehensible to undergraduates in the biological sciences, and yet with sufficient depth to provide a valued source of information to graduates engaged in both teaching and research. Our authors have been selected from among the best known in their respective fields. This volume discusses the manifold ways in which hormones control the reproductive processes in male and female mammals. The hypothalamus regulates both the anterior and posterior pituitary glands, whilst the pineal can exert a modulating influence on the hypothalamus. The pituitary gonadotrophins regulate the endocrine and gametogenic activities of the gonads, and there are important local feedback effects of hormones within the gonads themselves. Non-pregnant females display many different types of oestrous or menstrual cycles, and there are likewise great species differences in the endocrinology of pregnancy. But the hallmark of mammals is lactation, and this also exerts a major control on subsequent reproductive activity.

This volume contains the 1983 second edition of Textbook of Contraceptive Practice. The second edition represented a comprehensive reappraisal of the subject, taking account of the great expansion in information on all aspects of family planning that had occurred since the first edition was published in 1969. It emphasized the historical, social and political, and clinical perspectives of the subject. Advances in oral contraception, in the use of intra-uterine devices and in surgical methods of family planning were considered in relation to consumer choice and their overall risks and benefits. All techniques of contraception, from folk methods to methods of abortion and sterilization, were discussed in detail and evaluated.

In this second edition of Disorders of Thrombosis and Hemostasis in Pregnancy - A Guide to Management the content has been thoroughly updated, with a particular focus on strengthening the management sections to ensure that advice on management represents state of the art.

Why do American couples differ in the number of children they have? To answer this question the first major longitudinal study in American fertility was begun in 1957 with a series of interviews with parents of two children. Family Growth in Metropolitan America (1961) and The Third Child (1963) reported the results of the first two phases of this research project. In this book, in addition to evaluating the longitudinal design of the study, the authors report the results of the third and final interviews, a decade after the first, and attempt to answer such questions as: How well are couples able to predict their own fertility over the years? To what extent does the number of children desired affect the spacing of births? How is fertility affected by peer group relations, by the wife's participation in the labor force, by religion? Originally published in 1971. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

Reproduction in Mammals is intended to meet the needs of undergraduates reading zoology, biology, biochemistry, physiology, medicine, veterinary science and agriculture, and to be a source of information for advanced students and research workers. It is published as a series of small textbooks dealing with all major aspects of mammalian reproduction. Each of the component books is designed to cover independently fairly distinct subdivisions of the subject, so that readers can select texts relevant to their particular interests and needs. This volume consists of a series of thought-provoking essays by people with a number of very different backgrounds, including biology, comparative anatomy, psychology, psychiatry and moral philosophy. They discuss the physiology mechanisms, adaptive significance, clinical picture and social impact of a variety of patterns of human sexual behaviour, thereby providing a balanced and informative account of a highly sensitive and emotive subject.

Reproduction in Mammals is intended to meet the needs of undergraduates reading zoology, biology, biochemistry, physiology, medicine, veterinary science and agriculture, and to be a source of information for advanced students and research workers. It is published as a series of small textbooks dealing with all major aspects of mammalian reproduction. Each of the component books is designed to cover independently fairly distinct subdivisions of the subject, so that readers can select texts relevant to their particular interests and needs. This volume consists of a series of thought-provoking essays by people with a number of very different backgrounds, including biology, comparative anatomy, psychology, psychiatry and moral philosophy. They discuss the physiology mechanisms, adaptive significance, clinical picture and social impact of a variety of patterns of human sexual behaviour, thereby providing a balanced and informative account of a highly sensitive and emotive subject.

"Selected by" Choice" magazine as an Outstanding Academic Title for 1996""[Marsh and Ronner make for] a highly successful combination in which faultless clinical detail and a broad social and cultural approach are seamlessly woven to produce a very impressive and beautifully written historical work of the first importance." -- Irvine Louden, "Journal of the Social History of Medicine"

In "The Empty Cradle," Margaret Marsh and Wanda Ronner delve into the origins of the many misconceptions surrounding infertility as they explore how medical and cultural beliefs emerged throughout its controversial history. Drawing on a wide variety of sources -- including intimate diaries and letters, patient records, memoirs, medical literature, and popular magazines -- "The Empty Cradle" investigates the social, cultural, scientific, and medical dimensions of infertility over the past three hundred years.

Marsh and Ronner explore reactions -- among both physicians and husbands -- to the emerging scientific evidence that infertility was a condition for which men and women bear equal responsibility. The book concludes that infertility is still a subject affected by myth and misunderstanding. A lively and compelling history of a complex medical and cultural phenomenon, "The Empty Cradle" brings a valuable perspective to current debates about how we should think about and address the experience of infertility in our own time.

"Marsh and Ronner have sought to go beyond the published medical literature to disclose the voices of those most affected by the physiological and cultural condition of infertility... they have restored to the historical record the anguish and the hopes of women whoexperienced infertility." -- Rima D. Apple, "American Historical Review"

"The book's lucid explanations of medical terms and procedures will allow me to recommend it to my infertility patients. I plan to do so, trusting that it will give them a new perspective on their predicament. Knowing that it provided me a new perspective on both infertility and the practice of gynecology, I will also assign it an honored place in my medical library." -- Janet E. Shepherd, M.D., "Journal of the American Medical Association"

" "The Empty Cradle" demonstrates the profound impact of politics as well as culture on the development of medical practice. It is an excellent model for future scholarship on the complex relationship between science and society." -- Elaine Tyler May, "Journal of the History of Medicine and Allied Sciences"

'Mind-blowing ... It is a hugely important book ... His story is crucial' Matt Ridley, The Times One of the world's top behavioural geneticists argues that we need a radical rethink about what makes us who we are The blueprint for our individuality lies in the 1% of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences. In Blueprint, Robert Plomin, a pioneer in the field of behavioural genetics, draws on a lifetime's worth of research to make the case that DNA is the most important factor shaping who we are. Our families, schools and the environment around us are important, but they are not as influential as our genes. This is why, he argues, teachers and parents should accept children for who they are, rather than trying to mould them in certain directions. Even the environments we choose and the signal events that impact our lives, from divorce to addiction, are influenced by our genetic predispositions. Now, thanks to the DNA revolution, it is becoming possible to predict who we will become, at birth, from our DNA alone. As Plomin shows us, these developments have sweeping implications for how we think about parenting, education, and social mobility. A game-changing book by a leader in the field, Blueprint shows how the DNA present in the single cell with which we all begin our lives can impact our behaviour as adults.

Healthy Ageing and Aged Care takes an inter-disciplinary approach to supporting older people within the community and in care. It represents current Australian policies and practices and takes a holistic view of the older person, and emphasises the positive aspects of the ageing process, maintaining that people age in healthy ways and continue to be an integral part of their families and communities. This is one of the rewarding aspects of working with older people-assessing accurately and collaboratively putting in place strategies that can maintain the person's quality of life. The goal is for students to be able to develop those skills by engaging with the material in this book.

This book contributes in an important way to the psychoanalytic understanding and impact of Assisted Reproductive Technology on a majority of patients who have difficulties starting new families. Recent advances in reproductive technology and the increased use of techniques based upon it have created a need for psychoanalytic thinking and understanding of the psychological implications of Assisted reproductive procedures, in-vitro fertilization and other similar procedures.The recent and rapid advances in medical technologies confront us with a mandate in our clinical work to understand their complex impact on women, men, and children. However, attention to the intra psychic conflicts, traumatic experience of the use of such techniques has not been addressed in psychoanalytic literature. The developmental trauma and intra psychic conflicts of individuals using reproductive technologies are ubiquitous, yet it has been neglected as a topic of special interest in our clinical work.The centerpiece of these collective chapters deal with psychic trauma of infertility, the compulsion to repeat through persistent repeated use of assisted reproductive technology, anxiety about motherhood, and finally the lives of children who are born and do not know from where they came.These poignant topics deal with family complexes and the Oedipal circle, repetition compulsion, trials and failures, anxiety related to motherhood, egg and sperm donors, parental identity formation, infertility, trauma, and discussion of a contemporary film depicting the challenging and newly defined family structure.

Scientists investigating germ cells have, over the past 15 years, originated discoveries and innovations that give us valuable insights into the mechanisms that regulate not just stem cell function, but human development in its widest sense. With contributions from some of the leading researchers in the field, Male Germline Stem Cells: Developmental and Regenerative Potential assesses the implications of these discoveries for understanding the fundamental biology of germline stem cells as well as their potential for human stem cell-based therapies. This monograph covers many of the fundamental issues now being explored by today's generation of stem cell researchers, including the field's potential for regenerative medicine. Ranging from an assessment of the pluripotency of primordial germ cells and their possible applications in treating testicular cancer, to the recovery of once-mordant fertilization-competent sperm, this volume has it all. It is a reference point for any scientist involved in related research as well as being a timely summation of what could prove to be a hugely exciting and very fruitful area of inquiry.

Human oocyte cryopreservation has undergone rapid growth, with technical improvement and increasing clinical application over the last ten years. Storing eggs is ethical and gives many young women their most realistic chance of conception. Cryopreservation, however, is still considered by many as an experimental technique and conflicting reports are published as to its efficacy. For these reasons, it is necessary to give reproductive researchers and practitioners comprehensive and systematic information about the field. This book describes and analyses the history of human oocyte freezing, the main steps of technical evolution, and the pros and cons of different techniques. In addition, the clinical applications, long-term outcome, efficiency and safety of oocyte cryopreservation are detailed. The Handbook of Human Oocyte Cryopreservation gives a complete picture of the field today and is a valuable text for embryologists, cryobiologists, reproductive medicine practitioners and anyone involved in researching and implementing the technique.

This book is a contemporary statement of what is known about morphological development of the normal and abnormal human nervous system and puts into perspective the continued importance of changes that occur in the course of foetal development and how these processes may become defective. The first part of the book deals with the development of the central nervous system (CNS) from a morphological point of view including data from the fields of biochemistry, immunology and genetics. The second part reviews the genetic and nongenetic etiology of abnormal CNS development and discusses throughly all patologic syndromes that are related to disturbances of brain development. With the rapid progress in such modern branches of science as neurochemistry, genetics and molecular biology, this book will be invaluable for researchers working in these fields.

This book is dedicated to an update on metabolic disorders and their consequences on the developing nervous system. In the last ten years, major scientific advances in biochemical diagnosis have enabled the identification of many new disease entities, as well as a better classification of clinical symptoms and their correlation to biochemical defects. This volume provides an introduction to basic sciences specifically relevant to this disease group, then focuses on each subgroup in turn: hyperphenylalaninaemias, mitochondrial encephalomyopathies, organic acidoses, urea cycle defects, lysosomal storage and peroxylsomal disorders. Finally, a discussion of long term follow-up and family related issues also reports the results of a four-year research project led by the Mariani Foundation.