Mylene's light-hearted advice is all about navigating the world with confidence.' Daily Mail In this witty and uplifting book Parisian blogger Mylene Desclaux speaks tenderly and honestly about turning 50 and what it means for herself and for the other women in her entourage. Mylene assures us that we are still 'young women' in our fifties - but with more opportunities. 'By the time we're fifty, we've generally done all the important things - career, family. Now we can re-centre and discover a new energy within ourselves. It's our time to blossom - to reprogramme gently. To revitalise. We realise that we are the mistresses of our own lives . . . The desire to do battle disappears. We feel calm. And we know we're going to have time to make the most of it.' With acerbic French humour she distils the essence of getting the most out of your middle age and gives advice on everything from: * Relationships * Sex * Fashion * Dating * Skincare * Friendships * Kids * Beauty In WHY FRENCH WOMEN FEEL YOUNG AT 50 you will learn how to take pleasure from the simple things in life and how to make the most of your fifties, the Parisian way.

"Living in an age of constant gratification, economic influx and fragile egos, happiness has become increasingly elusive, yet it remains the Holy Grail, we search for all our lives. The purpose of this book is to suggest a cure for the ordinary day to day unhappiness which most people suffer from in today's world due to no obvious reasons. Since the goal of every human being on this Earth is to attain Happiness, it is hoped that after reading the book thoroughly and analysing as well as grasping the seven most important and practical steps suggested by the author, such as: - Change is constant - Live in the present - Live free from Attachment - Good Health - You can stall ageing - Be Content which will lead to Happiness - Love and Cheer up to be contented in your day-to-day life - Always think Positively and have Happy thoughts- Laughter/Humour is God's gift to Happiness, one can successfully tackle one's problems in life and achieve one's ultimate goal, i.e., to Remain Happy and Cheerful!

Ten years ago a group of experts assembled in Chicago to develop a consensus on the management of conditions previously described as intersex. The consequences of this consensus have been far reaching, including a change in nomenclature, the development of greater collaboration across geographical boundaries, and a move towards greater involvement of patients and parents. Moreover, an international registry was established, as well as research and clinical networks. This book brings together a thorough overview on all these topics. Furthermore, the major technological advances in diagnostic genetic and biochemical capabilities over the past 10 years are outlined in detail. Offering a comprehensive update on various aspects of disorders of sex development (DSD), this book will be essential reading to all clinicians who are involved in delivering health care to patients with a DSD, as well as scientists involved in biomedical research related to DSD.

Stuart and his wife Julie decided they were ready to have a baby. She went on vitamins and they went on one last vacation, because they thought it would be no time at all before she was pregnant. But that's not exactly how things went. For nearly two years, they endured grueling fertility treatments, beginning with charting temperatures and predicting ovulation, on to oral fertility drugs, through a laparoscopy, a slew of IUIs, and multiple IVFs, and, finally, a course of homeopathic remedies. Catawampus tells this tale of the madness and confusion of fertility treatments and all that those treatments entail but, this time, it's Stuart that tells the story. So, specimen collecting? Sure. Syringes, large and small? Yes. Heartache, frustration, and anger? Of course, but Stuart also shows what else was going on at the time, because, despite the fact that the fertility process can dominate a couple's focus, life continues to unfold. As such, the book is about a relationship between husband and wife, between parent and child, about friendship, and, ultimately, about what it means to be a father. Oh, yeah, it's also very funny. And filled with a choice selection of rants about popular culture, references to movies ranging from the ridiculous to the mostly-still-ridiculous, citations of literary classics, and a little bit of Nashville thrown in for fun. In the end, it's entertaining and poignant writing, and a necessary and underrepresented perspective of an important, hot-button issue.

The most important and the largest sex organ is located between the ears....and is commonly referred to as "the brain." Libido is a function of testosterone and erection is a function of free radicals. The very spark of life is fed by oxygen If you put out your free radical, oxidative fire, you extinguish your life If you douse your inner life-force spark, you smother your elan vital (life force). You can not live without your inner oxidative flame. Antioxidants pose a threat to the oxidative fire within. Oxygen and its electronically modified oxygen derivative (EMOD) progeny are the sine qua non (the essential condition) of man's very existence. This is an inarguable fact. Contrary to the common mantra of many authors, oxygen free radicals perform many crucial beneficial roles in sexual function and reproduction. Also contrary to popular claims, antioxidants are not the cure-all for sexual and reproductive problems. I have often said, "Man is the craziest critter on the planet." To back this up, I had suggested that all one had to do was to turn on the evening news or grab a newspaper. However, if you really want to see how crazy man is, just come with me through the history of aphrodisiacs and sexual prowess. So, let's undergo a reality check and scope out the history of these agents that claim to put more "zang in your wang," "zing in your thing" or greater "zippedy in your doo-da "

How we age is much more of a choice than you may think. Many people reach a stage when they are looking for something different. Others feel that time is running out, or they are "losing their looks." The answers to these anxieties rarely lie in a jar or a pill. As a healthy lifestyle is important in looking and feeling good, so our attitude is important in giving meaning and direction to our lives, and even improving our looks. Combining the latest research on health, ageing and well-being with 30 years experience of working with people, we present a constructive antidote to the myths and stereotypes around ageing, and a guide to an exciting, fulfilling future.

This book covers human female biology, how the menstrual cycle is controlled, how steroidogenesis is controlled and how the follicle and the egg are formed. This book covers male biology, and how steroid hormones are made, and how sperm are synthesised and matured. Then this book covers sex biology, such as how the brain deals with libido and sexual images, and how the brain controls erection and ejaculation. This book deals with how sperm are matured upon intercourse, how fertilisation takes place, and how the fertilised embryo is matured and implants in the uterus. The subjects of sexuality and homosexuality, chromosome disorders and hydatidiform moles are carefully discussed and considered. Sexual maturation of the foetus during pregnancy is carefully considered. This book carefully describes puberty, adrenarche and menarche. The subject of menopause is carefully considered. The subject of major bacterial and viral and sexual diseases is carefully considered as is the subject of reproductive cancers. In writing this book, care has been taken to update everything and check out the information available on medline and on the internet. This is a textbook for undergraduates, medical students and graduates describing all the details of human reproduction. It is also the only up-to-date book on the market. Having examined a total 70 books on human reproduction, obstetrics and gynaecology, they all, with no exceptions, include mostly out-of-date science. This is corrected in this book. This book is also a monograph for reproductive biology scientists, covering all the most recent findings in this field. It can also be sold as a general obstetrics and gynaecology information source for use by physicians, the general public and in libraries. This is a unique one-of-a-kind reference on human reproduction.

In this book the authors present current research in the study of spermatozoa. This compilation focuses on the biology, motility and function and chromosomal abnormalities of spermatozoa. Topics discussed are the epigenetic mechanisms in mammalian male germline; biological characteristics of sperm in two oyster species; sub-cellular dynamics occurring during capacitation of mammalian spermatozoa; new perspectives on the study of prion and prion-like proteins; meiotic segregation studies in spermatozoa of males carrying a structural chromosome abnormality; testicular germ cell apoptosis during orchitis; the influence of leukocytospermia on semen parameters; and spermatozoa motility and morphology.

In this book the authors present current research in the study of foetal development and its stages of growth, maternal influences and potential complications. Topics discussed in this compilation include the equine foetal development, fetomaternal interaction and potential complications during pregnancy; comparative anatomy, development and functional significance of the mammalian yolk sac; influence of exercise training on e-NOS expression, nitric oxide production and mitochondrial function in the human placenta; maternal melamine and foetal development; and immunolocalisation of syntaxin2 in sinusoidal endothelial cells during mouse liver development.

This personal scientific memoir describes how a chance observation concerning artery disease in children with rare inherited abnormalities of metabolism, often called experiments of Nature, led to the discovery of a new theory of heart disease, cancer and diseases of ageing. As explained in subsequent chapters, this new theory places the amino acid homocysteine at the heart of altered metabolism of diseases of ageing. Not only does this theory illuminate and explain the origin of these diseases, development of this theory logically leads to a novel and revolutionary metabolic and nutritional program for disease prevention and treatment, potentially benefiting individuals and populations.

Infertility affects about 15% of couples in western societies. In addition to isolation, infertility challenges women's sense of identity, expectations of their life trajectory and their perceived value in society. This book presents current research on the genetic factors, treatment risk and benefits, and social and psychological consequences of infertility. Topics include the traditional Chinese medicine approach to fertility management; adverse outcomes of assisted reproduction techniques; the impact of follicular fluid components and embryo-endometrial cross-talk on the oocyte quality or embryo viability; iatrogenic damage incurred during fertility treatment upon gamete competence and embryonic viability; genetic factors of male infertility; animal models for studying female infertility; and treatment of endometriosis associated with infertility.

A Common Thread is a collection of sixteen brave and honest accounts of fertility issues and miscarriage. Each journey is unique; yet each contributor shares truthfully from their heart the highs and lows they have been through; how their journey has affected their faith and how God has brought them through. Although the physical, emotional and mental toll can be unbearable for those who find themselves facing these battles, there is hope. Within this book you will read the stories of those who have experienced successful IVF, failed IVF, multiple miscarriages, miscarriage after having children, adoption, miracle births, and those who have never been able to have children. Although we all experience the journey differently, we all share 'a common thread' of understanding. You are not alone.

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential "ripple effects", aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

In this book, the authors present current research in the study of the anatomy, physiology and pathology of the testes. Topics discussed in this compilation include the roles and regulatory mechanism of proton pumping V-ATPase in spermatozoa and epididymis physiology; oxidative stress as a converging mechanism of testicular damage; the pathophysiology of the testis after ischemia reperfusion injury; beta-actin implications in the seminiferous tubule; heat stress damage in mammalian testis; and the effect of plasticisers on testis and Sertoli cell functions.

In Taking Baby Steps, Jody Lynee Madeira takes readers inside the infertility experience, from dealing with infertility-related emotions through forming treatment relationships with medical professionals to confronting difficult medical decisions. Based on hundreds of interviews, this book investigates how women, men, and medical professionals negotiate infertility's rocky terrain to create life and build families-a journey across personal, medical, legal, and ethical minefields that can test mental and physical health, friendships and marriages, spirituality, and financial security.

Americans age 65 and over are an important and growing segment of our population. Many federal agencies provide data on aspects of older Americans' lives, but it can be difficult to fit the pieces together. Thus, it has become increasingly important for policymakers and the general public to have an accessible, easy-to-understand portrait that shows how older Americans are faring. This book provides a comprehensive picture of our older population's health and well-being.

Reproductive donation is the most contentious area of assisted reproduction. Even within Europe there are wide variations in what is permitted in each country. This multi-disciplinary book takes a fresh look at the practices of egg, sperm and embryo donation and surrogacy, bringing together ethical analysis and empirical research. New evidence is offered on aspects of assisted reproduction and the families these create, including non-traditional types. One of the key issues addressed is should children be told of their donor origin? If they do learn the identity of their donor, what kinds of relationships may be forged between families, the donor and other donor sibling families? Should donation involve a gift relationship? Is intra-familial donation too close for comfort? How should we understand the growing trend for 'reproductive tourism'? This lively and informed discussion offers new insights into reproductive donation and the resulting donor families.