Ageing is the accumulation of changes in an organism or object over time. Ageing in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. More people are reaching older age today than ever before and the incidence of dementia is thus expected to rise. It is important to investigate the possible prevention of dementia and cognitive decline. This new book gathers the latest research from around the globe in this field of study and related topics such as cardiovascular disease and cognitive function, physical exercise and cognitive function in the elderly, the dementia diagnosis, the role of MRI in Alzheimer's disease, oestrogen decline effects on the mental health of ageing women and the relationship between dementia and depression.

Protecting the reproductive potential of young patients undergoing cancer therapy is increasingly important. With modern treatment protocols, 80% of patients can be expected to survive. It has been estimated that up to one in 250 young adults will be a survivor of childhood cancer in the future; infertility, however, may be a consequence. As a wide range of fertility preservation methods are increasingly offered by clinicians, this systematic and comprehensive textbook dealing with the cryobiology, technology and clinical approach to this therapy will be essential reading to infertility specialists, embryologists, oncologists, cryobiologists, ObGyns, andrologists, and urologists with an interest in fertility preservation. Fertility Cryopreservation reviews all the techniques of this increasingly important field within reproductive medicine. It covers the basic principles of pertinent cryobiology, and contains major sections on the different therapies available, written by international specialists combining experience from both academic centers and commercial industries.

How well do you really know your body?

How easy do you think it will be for you to get pregnant - or NOT to get pregnant?

You've probably never really been educated about your reproductive years - perhaps you learnt everything you know from friends, or from the media, or online. You might be ready for a baby now; or, like so many other women, you might want to delay the birth of your first child while you establish your career. Perhaps you're thinking about freezing your eggs.

Professor Joyce Harper is an internationally recognized expert on female fertility and fertility education, and in 12 chapters she covers the full scope of your reproductive years, from your first period to menopausal symptoms. Her straightforward, scientifically based advice will give you all the information you need to make informed decisions about your reproductive choices. Only when you really understand your menstrual cycle works can you optimise your lifestyle to get pregnant successfully - while being properly aware of how and when your fertility will decline.

Your Fertile Years answers all your questions about things like egg freezing and IVF, and debunks not only the myths surrounding fertility treatment, but also the misinformation and scare stories that surround conception and pregnancy, including the bottom line on supplements, diet and holistic therapies.

A shining beacon in the murky fertility landscape, this book will accompany you through your fertile years, giving you the guidance you need to make decisions that work for you, your family, your career and your body.

Artificial Insemination and Treatment of Infertility in Dairy Animals by Honnappagol and Tandle is a handy work of 16 well experienced faculties drawn from different departments of higher learning. Most of them are actively engaged in under-graduate and post-graduate teaching with considerable expertise. Adequate care has been exercised by the editors to incorporate all the aspects of artificial insemination and infertility in the chapters form 1 to 20 so that it can serve as a real guide to the students and veterinarians and in turn minimizing the possible economic losses to the dairy animal owners and dairy Industry. Adequate care has been taken to include all spheres of infertility starting from endocrinology of estrous cycle, role of nutrition, feed formulation, breeding strategies, estrus detection aids, recent advances in reproduction controlled breeding, fertility improvement use of ultrasound and laparoscopy, therapeutic management of infertility and reproductive disease control. Practical knowledge and skill in respect of handling, storage and evaluation of frozen semen, safety handling of cryocans and liquid nitrogen, factors affecting success rate in artificial insemination programme and drugs and hormones used in treating reproductive disorders is also provided.

Ageing or aging is the accumulation of changes in an organism or object over time. Ageing in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. This book examines several important issues in the field.

The word longevity is sometimes used as a synonym for "life expectancy" in demography. Aging is the accumulation of changes in an organism or object over time. Aging in humans refers to a multidimensional process of physical, psychological, and social change. Some dimensions of aging grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Aging is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions. Age is usually measured in full years -- and months for young children. At present, the biological basis of aging is unknown. This book presents the latest research in this dynamic field.

The goal of this work was the development of a biomechanical model of the human eye. The research work SEE-KID (Software Engineering Environment for Knowledge based Interactive Eye motility Diagnostics), described in this work, tries to connect aspects of biomechanical modelling with methods of modern Software Engineering. An interactive software system was implemented, called SEE++ which allows physicians to obtain a better understanding of the mechanics of eye movements. This software visualizes and simulates pathologies and eye muscle surgeries, based on the biomechanics of the eye. It can be used in preoperative planning, medical training and basic research, and shows how Medical-Informatics can improve the diagnosis and treatment of patients. The project SEE-KID is based also on the software system Orbit (www.eidactics.com) and on other biomechanics software. The SEE-KID project and the SEE++ software system are meant as extension to Orbit with more clinical relevance while providing essential functionality similar to what Orbit offered. Additionally, SEE-KID tries to extend existing functionality and combine different aspects of modelling into one single system.

As Louise Brown -- the first baby conceived by in vitro fertilization -- celebrates her 30th birthday, Margaret Marsh and Wanda Ronner tell the fascinating story of the man who first showed that human in vitro fertilization was possible.

John Rock spent his career studying human reproduction. The first researcher to fertilize a human egg in vitro in the 1940s, he became the nation's leading figure in the treatment of infertility, his clinic serving rich and poor alike. In the 1950s he joined forces with Gregory Pincus to develop oral contraceptives and in the 1960s enjoyed international celebrity for his promotion of the pill and his campaign to persuade the Catholic Church to accept it.

Rock became a more controversial figure by the 1970s, as conservative Christians argued that his embryo studies were immoral and feminist activists contended that he had taken advantage of the clinic patients who had participated in these studies as research subjects.

Marsh and Ronner's nuanced account sheds light on the man behind the brilliant career. They tell the story of a directionless young man, a saloon keeper's son, who began his working life as a timekeeper on a Guatemalan banana plantation and later became one of the most recognized figures of the twentieth century. They portray his medical practice from the perspective of his patients, who ranged from the wives of laborers to Hollywood film stars.

The first scholars to have access to Rock's personal papers, Marsh and Ronner offer a compelling look at a man whose work defined the reproductive revolution, with its dual developments in contraception and technologically assisted conception.

An age old mystery, the development of the microscopic embryo into exceedingly complex plants and animals--into roses and cacti, elephants and blue whales, apes and human beings--stands as one of the most fundamental and important questions facing modern biologists. How does one cell give rise
to so many millions of cells? How do they divide so as to form hearts, brains, eyes, and ears? Where in this pin-head-sized object is all this information encoded? Now, in The Triumph of the Embryo, biologist Lewis Wolpert answers these and other questions in a lucid tour of embryology, which offers
the latest theories in this fascinating field.
Filled with rich and unusual examples, metaphors, and descriptions, Wolpert moves beyond his overall narrative to discuss the many issues it raises, such as aging, cancer, regeneration, and evolution. Readers discover why all calico cats are female; encounter a fruit fly engineered to grow a leg
out of its head; and find out why there seems to be a 110 year age barrier for the human body. Clearly written and illustrated with striking examples, The Triumph of the Embryo offers a dazzling look at the marvels of modern biology.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Now in a completely newly revised and expanded second edition, this comprehensive text presents the current state of the art in our understanding and management of polycystic ovary syndrome (PCOS), the most common hormonal disorder of reproductive aged women. The numerous bothersome symptoms of PCOS include menstrual irregularities, hirsutism, acne, scalp hair thinning, weigh excess and infertility; additionally, as they age, women with PCOS are at a higher risk for metabolic abnormalities such as diabetes and dyslipidemias, as well as for cardiovascular disease and even certain cancers. Despite improvements in our understanding of this condition, the exact cause/s of PCOS remain elusive; genetic, hormonal, metabolic and environmental underpinnings are all suggested as relevant. All chapters have been updated, with eight new chapters added across seven thematic sections. Part one discusses the epidemiology of PCOS in both adults and adolescents. Part two covers the pathophysiology of PCOS, including genetics, the hypothalamo-pituitary-ovarian and the hypothalamo-pituitary-adrenal axes, insulin resistance, inflammation, and obesity. The next three sections present the various management strategies, medical and surgical, for harnessing the symptomatology, including PCOS-related infertility; these chapters include added case material to provide real-world examples of the treatments in action and their efficacy. Part six covers the comorbidities that women with PCOS commonly encounter, such as issues of mental health, sleep disturbances, endometrial hyperplasia, and cancer, as well as examines the economic burden of PCOS. The final section discusses emerging concepts surrounding possible mechanisms and potential therapeutic approaches to PCOS, including angiogenic dysfunction, the role of vitamin D, future potential therapies to targeted AMH signaling. The closing chapter, by familiarizing the readers with the intergenerational implications of PCOS and by raising awareness of potential "ripple effects", aims at alerting the community on a need for vigilance as regards the health of PCOS progeny. With contributions from leaders in the field, Polycystic Ovary Syndrome, Second Edition remains the gold-standard text on this common medical condition and a valuable resource for the wide range of healthcare professionals engaged in caring for the women with PCOS (including but not limited to reproductive endocrinologists, gynecologists, family physicians, dermatologists, mental health professionals), for the aspiring women's health providers of tomorrow, and for the researchers who are striving to unravel the mysteries of the complex entity that PCOS is.

The ageing process changes body composition and thus nutritional status changes as one gets older. At the same time the body becomes more susceptible to diseases and diet becomes an even more significant or at least visibly significant than in earlier years. Moreover, there is frequently socio-economic downward drifting in this age group making nutritious foods more difficult to afford. This book presents the latest research in this vital field.

This scarce antiquarian book is included in our special Legacy Reprint Series. In the interest of creating a more extensive selection of rare historical book reprints, we have chosen to reproduce this title even though it may possibly have occasional imperfections such as missing and blurred pages, missing text, poor pictures, markings, dark backgrounds and other reproduction issues beyond our control. Because this work is culturally important, we have made it available as a part of our commitment to protecting, preserving and promoting the world's literature.

Ageing is any change in an organism over time. Ageing refers to a multidimensional process of physical, psychological, and social change. Some dimensions of ageing grow and expand over time, while others decline. Reaction time, for example, may slow with age, while knowledge of world events and wisdom may expand. Research shows that even late in life potential exists for physical, mental, and social growth and development. Ageing is an important part of all human societies reflecting the biological changes that occur, but also reflecting cultural and societal conventions.

This atlas presents a series of photographic illustrations and line drawings that summarize the major developmental events that occur during organogenesis in the opossum (Didelphis virginiana).It will be of interest to General Biologists, Zoologists, Wildlife Biologists, Embryologists and Medical Scientists.

Say "biological clock" and most people think "women." Yet men have biological clocks too, reveals Dr. Harry Fisch, one of the country's leading experts in male infertility and author of this groundbreaking new book, "The Male Biological Clock." Men's clocks tick at a different rate from women's and of course cause an entirely different set of bodily and behavioral changes over the course of a lifetime. But while men's clocks don't strike a "midnight" toll heralding an end to fertility the way menopause does for women, male fertility, testosterone levels, and sexuality all do decline with age. Dr. Fisch's book emphasizes that even young men can have testosterone levels as low as those of much older men, leading to infertility, sexual problems, and other serious health issues. Another startling revelation is that men over thirty-five are twice as likely to be infertile as men younger than twenty-five. In addition, as men age, the quality of their sperm declines significantly, giving rise to an increased chance of a Down syndrome baby, other genetic abnormalities, and miscarriage. Every couple should know all the risks and issues facing men, because these affect two of the most important things in their life: their ability to have children and their capacity to have good sex.

"The Male Biological Clock" is must reading for every man and every couple who is struggling to have children or improve their sex life. Many of Dr. Harry Fisch's findings are startling -- beginning with the fact that infertility is not mostly a women's problem -- and he offers many helpful suggestions for how to deal with declining testosterone, changing sexual needs, and the fertility industry.

We have allheard stories of men becoming fathers in their seventies or even eighties, yet most of us are unaware that these are dangerously deceptive exceptions. Older men face a number of increased risks as fathers, and often find their sex lives and well-being changing considerably. The good news: Much can be done to slow down and even reverse the effects of a man's biological clock. "The Male Biological Clock" tells you what you need to know and how you can achieve optimal fertility and sexuality.

Combining attention to lived experience with the critical tools of ethics, Karey Harwood explores why many women who use the tools of high-tech assisted reproduction tend to use them repeatedly, even when the results are unsuccessful. With a compassionate look at the individual decision making behind the desire to become pregnant and the use of assisted reproductive technologies (ART), Harwood extends the public conversation beyond debates about individual choice by considering the experiences of families and by addressing the broader ethical problems presented by these technologies. Incorporating the personal narratives of women who are members of RESOLVE, the nation's leading organization for people who are infertile, Harwood demonstrates that repeated unsuccessful attempts to use ART may ironically help women come to terms with their infertility. Yet ART is problematic for a number of reasons, including the financial, physical, and emotional costs for women and their families as well as the effects of these technologies on the health and well-being of the children conceived. Issues such as consumerism, workplace norms that encourage delayed childbearing, and narrow definitions of family all come into play. By considering both emotional and ethical dimensions, Harwood offers a humanistic account of infertility and its resolution in a twenty-first-century American context.

Book & CD. One of the most striking demographic changes over the last century in Western countries has been the rapid growth, both absolute and relative, of the oldest-old population, to such an extent that living beyond the age of 80 years constitutes a new stage of life. But what is life like after 80? Rather than scrutinizing the pathologies of very old age, this book enquires into the normal aging of the oldest old, their health trajectories, their socio-demographic inequalities; it analyses their daily life, including their social relationships, social support, and activities, and observes how the oldest old adapt to the multiple stresses and challenges of very old age. The book reports major results obtained from Swilsoo, a long-term longitudinal study based on two cohorts of octogenarians. The two cohorts were assessed on an approximately yearly basis, the first for 9 waves from 1994 to 2004, with 340 participants at inception, and the second for 5 waves from 19v9 to 2004, initially with 377 participants. The book demonstrates that many common stereotypes concerning the oldest old are false. For examples, their main shared characteristic is not sickness, but frailty, which affects them in different ways. A long life does not necessarily culminate in dependence. Dependence is a risk -- especially among persons of lower socio-economic status -- but not an ineluctable outcome. It also helps to bring out the importance of social and psychological resources in the lives of the oldest old. Although multiple stresses such as negative health-related changes or self-reported bereavements of a loved one often occur in the life of the elderly and affect their health and well-being, the very old can take advantage of various resources or adjustment mechanisms to help preserve their well-being and robustness. The book shows for instance that the preservation by the elderly of a positive and active role within the family is a boon to their health and that the continuation of leisure activities or the effective use of psychological resources counters the negative effects of frailty on well-being.

Personalized medicine is what this book is about-tailoring your lifestyle, food, medicines, treatments, and reproductive choices to your genetic signature. According to Dr. Andrew Y. Silverman, MD, PhD, 'The desire to influence the sex of the next child is probably as old as recorded history."

'Gender selection is possible because of the way in which sex is determined by our chromosomes. Dr. Ericsson devised patented methods by which X and Y sperm can be separated through filtering processes. Sperm are 'layered" over a column of human serum albumin, and they swim down the gradient where they are collected in the bottom layer.

'The fraction of sperm that contains the male (Y) bearing sperm is used for insemination if a boy is desired. It is effective 70-75% of the time.

'The fraction of sperm that contains the female (X) bearing sperm is used for insemination if a girl is desired. It is effective 70-72% of the time."

Use personalized medicine more effectively. Empower consumers by interpreting DNA testing and learning more about infant gender choice by genetics.

Among the many applications of stem cell research are nervous system diseases, diabetes, heart disease, autoimmune diseases as well as Parkinson's disease, end-stage kidney disease, liver failure, cancer, spinal cord injury, multiple sclerosis, Parkinson's disease, and Alzheimer's disease. Stem cells are self-renewing, unspecialised cells that can give rise to multiple types all of specialised cells of the body. Stem cell research also involves complex ethical and legal considerations since they involve adult, foetal tissue and embryonic sources. This book brings together leading research from throughout the world with particular focus on stem cells and cancer research.

Remaking Eden is a fascinating exploration of the future of reprogenetic technologies - a cautiously optimistic look at the scientific advances that will allow us to engineer life in ways that were unimaginable just a few short years ago. Indeed, in ways that go far beyond cloning, and that are at once more thrilling and more frightening. Could a woman give birth to her identical twin sister? Could a child have two genetic mothers? Could a man become pregnant? Could parents choose not only the physical characteristics of their children-to-be, but personalities and talents as well? Will genetic enhancement ultimately change the very nature of our species? The answers will excite some and alarm others. Silver demystifies the science involved in all these possibilities, calmly and efficiently dismantling our preconceptions and misconceptions. Throughout, he examines the profound ethical questions raised by these new technologies. Yet he reminds us that the desire both to have children and to provide them with all possible advantages in life is a uniquely powerful force - a force, he suggests, that will overcome all political and societal attempts to curb the use of reprogenetics.

This Medical thriller opens with the birth of a severely disfigured child the details the history of the main characters starting from their meeting at one of the most historic footraces in the world - The Dipsea Race. Their courtship begins with conflict but grows into one that will inspire readers to achieve in their own relationships. The novel encompasses three decades and dramatically unfolds after a seemingly small error occurs in a frozen sperm sample. As we embark on the 21st century sometimes ethical issues lag behind the swift pace of medical technology. Readers will grasp the premise of Frozen Identity and enjoy the ride. The main characters are competitive athletes, adding texture, drama and a common bond held by all who strive for physical accomplishment

Winner, 2007 Rachel Carson Prize given by the Society for Social Studies of Science (4S). Assisted reproductive technology (ART) makes babies and parents at once. Drawing on science and technology studies, feminist theory, and historical and ethnographic analyses of ART clinics, Charis Thompson explores the intertwining of biological reproduction with the personal, political, and technological meanings of reproduction. She analyzes the "ontological choreography" at ART clinics--the dynamics by which technical, scientific, kinship, gender, emotional, legal, political, financial, and other matters are coordinated--using ethnographic data to address questions usually treated in the abstract. Reproductive technologies, says Thompson, are part of the increasing tendency to turn social problems into biomedical questions and can be used as a lens through which to see the resulting changes in the relations between science and society. After giving an account of the book's disciplinary roots in science and technology studies and in feminist scholarship on reproduction, Thompson comes to the ethnographic heart of her study. She develops her concept of ontological choreography by examining ART's normalization of "miraculous" technology (including the etiquette of technological sex); gender identity in the assigned roles of mother and father and the conservative nature of gender relations in the clinic; the naturalization of technologically assisted kinship and procreative intent; and patients' pursuit of agency through objectification and technology. Finally, Thompson explores the economies of reproductive technologies, concluding with a speculative and polemical look at the "biomedical mode ofreproduction" as a predictor of future relations between science and society.