Science is on the cusp of a revolutionary breakthrough. We now understand more about ageing - and how to prevent and reverse it - than ever before. In The Telomerase Revolution, Dr Michael Fossel, who has been at the cutting edge of ageing research for decades, describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to intervene in age-related disease, dramatically extend life spans and even reverse human ageing. Telomerase-based treatments are already on offer, and have shown early promise, but much more potent treatments will become available over the next decade. This is the definitive work on the latest science of human ageing, covering both the theory and the clinical implications, taking readers to the forefront of one of the most remarkable advances in human medicine.

The development of new reproductive technologies has raised urgent questions and debates about how and by whom these treatments should be controlled. On the one hand individuals and groups have claimed access to assisted reproduction as a right, and some have also claimed that this access should be available free of charge. As well as clinically infertile heterosexual couples, this right has been claimed by single women, gay couples, post-menopausal women, and couples who wish to delay having children for various reasons. Others have argued that a desire to have children does not make it a human right, and, moreover, that there are some people who should not be assisted to become parents, on grounds of age, sexuality, or lifestyle. Mary Warnock steers a clear path through the web of complex issues underlying these views. She begins by analyzing what it means to claim something as a 'right', and goes on to discuss the cases of different groups of people. She also examines the ethical problems faced by particular types of assisted reproduction, including artificial insemination, in-vitro fertilization, and surrogacy, and argues that in the future human cloning may well be a viable an

The concept of reproductive health promises to play a crucial role in improving health care provision and legal protection for women around the world. This is an authoritative and much-needed introduction to and defence of the concept of reproductive health, which though internationally endorsed, is still contested. The authors are leading authorities on reproductive medicine, women's health, human rights, medical law, and bioethics. They integrate their disciplines to provide an accessible but comprehensive picture. They analyse 15 cases from different countries and cultures, and explore options for resolution. The aim is to equip readers to fashion solutions in their own health care circumstances, compatibly with ethical, legal and human rights principles.

A Scientific Book Club selection, this comprehensive account of the nature and function of the hormones in the processes of sex and reproduction. Originally published in 1942. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

This book is designed to meet the needs of nurse practitioners, other advanced practice nurses, and allied health professionals working in women's health, primary care, and other specialties. The multiple roles the clinician embraces in menopause management include that of direct caregiver, manager of therapeutics, educator, and interdisciplinary team member or leader. This book provides updated, evidence based information on the menopause transition from the late reproductive stage to post-menopause to optimize the interaction of the clinician and the individual woman in each of those roles. Women's lived experiences of menopause and women's concerns regarding both the menopause transition and the choice of care options are included as critical components of shared therapy decisions. The review of natural menopause physiology and the variability of menopause symptoms are inclusive of diverse women and diverse trajectories. The impact of menopause on chronic disease, sleep, weight and nutrition, mood and cognition, urogenital health and sexuality, as well as vasomotor symptoms are each developed as individual topics by experts in those fields. Evidence based management using hormonal and non-hormonal options, and life-style and other complementary interventions are discussed with the most updated advantages and disadvantages of each treatment option. Consistent with advanced practice nursing theory, the approach is whole patient focused.

Leading gender and science scholar Sarah S. Richardson charts the untold history of the idea that a woman's health and behavior during pregnancy can have long-term effects on her descendants' health and welfare. The idea that a woman may leave a biological trace on her gestating offspring has long been a commonplace folk intuition and a matter of scientific intrigue, but the form of that idea has changed dramatically over time. Beginning with the advent of modern genetics at the turn of the twentieth century, biomedical scientists dismissed any notion that a mother-except in cases of extreme deprivation or injury-could alter her offspring's traits. Consensus asserted that a child's fate was set by a combination of its genes and post-birth upbringing. Over the last fifty years, however, this consensus was dismantled, and today, research on the intrauterine environment and its effects on the fetus is emerging as a robust program of study in medicine, public health, psychology, evolutionary biology, and genomics. Collectively, these sciences argue that a woman's experiences, behaviors, and physiology can have life-altering effects on offspring development. Tracing a genealogy of ideas about heredity and maternal-fetal effects, this book offers a critical analysis of conceptual and ethical issues-in particular, the staggering implications for maternal well-being and reproductive autonomy-provoked by the striking rise of epigenetics and fetal origins science in postgenomic biology today.

Recent developments in methods of contraception have presented women with a wider range of options than ever before. At the same time, however, scare stories - particularly about the Pill - have spread anxiety and confusion. In this third edition of Contraception, Anne Szarewski and John Guillebaud assess all the evidence, including the new guidelines which were issued by the Committee of Safety of Medicines (CSM) in May 1999 following a review of the 1995 scare stories. They describe the latest methods, including new types of condoms, Persona, and Mirena, and cut through the conflicting information to give you the clearest and most reliable advice you will find anywhere. From reviews of previous editions: 'A model of clearly presented, unpatronising, up-to-the- minute information ... the current definitive book on the subject.' Vogue 'Excellent.' British Journal of Family Planning 'Essential reading for anyone thinking of changing their family planning method.' Woman 'this is the book to buy ... Written by expert gynaecologists... with textbook clarity, it's one of the most comprehensive guides around... an invaluable book.' Health and Fitness

Approximately five million children have been born worldwide as a result of assisted reproductive technology (ART). These techniques are now practised independently in most of the world's nations. Although the vast majority of ART parents and children are healthy following the procedures involved, there is an imperative to maintain a high standard of practice and monitor outcomes carefully. Interpretation of outcome data is difficult for a variety of reasons. As ART technologies evolve and new variants are established, the need for robust assessment of outcomes increases. This book gives a thorough review of potential complications of ART, with detailed analysis of outcome data for the various conditions described. A worldwide perspective is given throughout, with an international team of chapter authors.

Die moderne Reproduktionsmedizin wird oftmals als letzte Chance von Partnern ausgewahlt, um ihren starken, bisher unerfullten Wunsch nach einem eigenen Kind einzuloesen - ungeachtet dessen, dass sie oeffentlich sehr kontrovers diskutiert werden und haufig auf grosse Ablehnung stossen. Die Teilnahme an einer Reproduktionsbehandlung ist kostenintensiv: Zusatzlich zu den finanziellen Kosten der medizinischen Behandlung kommen noch weitere subjektive Kosten hinzu, so z.B. ein erheblicher Zeitaufwand wahrend der Fertilisierungstherapien oder aber auch das Ertragen koerperlicher und psychischer Belastungen. Die vorliegende Arbeit erforscht die Einstellung der Betroffenen zur Reproduktionsmedizin und was sie mit einem Kind verbinden. Daruber hinaus wird erforscht, wie die ungewollt kinderlosen Partner die koerperlichen, psychischen und finanziellen Belastungen erleben und bewerten.

'It is very hard to produce a timely book about a subject that changes as quickly as technologically assisted reproduction, but John Harris and Soren Holm have managed to do exactly that. The fourteen essays in this small volume provide an extremely useful and highly readable overview of the key moral, legal, and social themes raised by new ways of making babies. . . . The book is unique in that it offers perspectives on all these topics from a variety of disciplines and professions as well as from a broad range of national and cultural perspectives.' Arthur Caplan, British Medical Journal

The must-have fertility plan that will soothe your mind, nourish your body and maximise your chances at having a baby. Leading fertility counsellor, Ann Bracken, draws together her years of expertise in the field with this supportive guide that will boost fertility by putting wellbeing at the heart of your journey. Ann breaks down the mindfulness-based stress reduction techniques that are scientifically-proven to combat the stress caused by fertility problems and offers clear, practical advice and tips on how to nurture your health and wellbeing - to optimise your fertility and inspire positivity during difficult times. Includes chapters on: * How to manage the psychological and emotional impacts of fertility problems * Mindfulness Practice * Information on Reproductive Treatment * Natural Health Therapies * Nutrition & Supplements to Boost Fertility, by Dr Marilyn Glenville * Restorative Yoga and Mindful Movement * Fertility Thinking through CBT * Self-Care * Taking care of your relationships * Useful Resources Featuring line illustrations to complement the text, journaling exercises throughout, and a foreword by pioneer of Mind-Body Medicine, Dr Alice Domar. 'A definite must-read regardless as to where you are on your journey' My Fertility Specialist Magazine 'A much-needed antidote to the all-too-often stressful and soul-searching path to parenthood. I will be recommending it to my fertility patients' Emma Cannon, integrated fertility expert, author of The Baby-Making Bible 'This book provides the perfect balance outlining the integrative mind and body approach and provides an essential complement to the medical aspects of the fertility journey' Dr James Nicopoullos, Consultant Gynaecologist?& subspecialist in Reproduce Medicine, The Lister Clinic, Lister Hospital, Chelsea, London 'In this book Ann Bracken has compiled what you need to know in an easily accessible, friendly and compassionate format' Dr Alice D Domar, Associate Professor in Obstetrics, Gynaecology and Reproductive Biology, Harvard Medical School and Executive Director of the Domar Center for Mind/Body Health

Women and Exercise is an invaluable resource for all physicians, from general practitioners to specialists seeking information outside their specialty, who need up-to-date information and expert advice about women and exercise.

This cutting-edge text for surgeons specializing in Reproductive Medicine details how the latest minimally invasive developments impact on operations in their repertoire. Illustrated with color photographs and surgical videos, this will be an essential reference in a fast-moving field.

A comprehensive integrative handbook on fertility treatment, and Assisted Reproduction Techniques (ART), the book is written by specialist contributors for health professionals and Complementary and Alternative Medicine (CAM) practitioners, and for those seriously considering ART themselves. Integrated approaches to infertility offer both a greater awareness and understanding of the combination of factors that can influence the chances of success when undergoing different types of ART. Leading experts review the evidence and discuss the benefits of different approaches to support the physiological and emotional aspects of fertility and fertility treatment. The book covers everything from identifying and treating conditions that may reduce fertility, including immunological abnormalities and specific male and female factors, to how nutrition, acupuncture, reflexology and yoga can support couples going through assisted reproduction, including helping to improve some immunological aspects. There is also a chapter that looks specifically at support for the over 40's.

Winner of the NCTE George Orwell Award for Distinguished Contribution to Honesty and Clarity in Public Language Although Roe v. Wade identified abortion as a constitutional right in1973, it still bears stigma-a proverbial scarlet A. Millions of Americans have participated in or benefited from an abortion, but few want to reveal that they have done so. Approximately one in five pregnancies in the US ends in abortion. Why is something so common, which has been legal so long, still a source of shame and secrecy? Why is it so regularly debated by politicians, and so seldom divulged from friend to friend? This book explores the personal stigma that prevents many from sharing their abortion experiences with friends and family in private conversation, and the structural stigma that keeps it that way. In public discussion, both proponents and opponents of abortion's legality tend to focus on extraordinary cases. This tendency keeps the national debate polarized and contentious, and keeps our focus on the cases that occur the least. Professor Katie Watson focuses instead on the cases that happen the most, which she calls "ordinary abortion." Scarlet A gives the reflective reader a more accurate impression of what the majority of American abortion practice really looks like. It explains how our silence around private experience has distorted public opinion, and how including both ordinary abortion and abortion ethics could make our public exchanges more fruitful. In Scarlet A, Watson wisely and respectfully navigates one of the most divisive topics in contemporary life. This book explains the law of abortion, challenges the toxic politics that make it a public football and private secret, offers tools for more productive private exchanges, and leads the way to a more robust public discussion of abortion ethics. Scarlet A combines storytelling and statistics to bring the story of ordinary abortion out of the shadows, painting a rich, rarely seen picture of how patients and doctors currently think and act, and ultimately inviting readers to tell their own stories and draw their own conclusions. The paperback edition includes a new preface by the author addressing recent cultural developments in abortion discourse and new legal threats to reproductive rights, and updated statistics throughout.

The thirteen million women now between the ages of forty-five and fifty-four have focused attention on menopause as a major health issue and greatly increased the demand for information on this once taboo topic. In Turning Point, biologist and author, Sue Furman puts menopause into perspective as one of many hormone-driven events in the continuum of a women's physical and emotional growth.
Furman takes a close look at the powerful influence hormones have on a woman's life, from bone growth and memory functions, to sometimes even swaying a woman's choice of Mr. Right. She then looks at the myriad symptoms that may arise around the time of menopause, including hot flashes, mood swings, migraine headaches, and palpitations, and explains exactly what is happening when these symptoms occur and how to alleviate or cope with them. Finally, Furman discusses the pros and cons of hormone replacement therapy (HRT) and how simple life-style choices like good-nutrition and moderate exercise can have a significant impact on the menopause transition.
Debunking the many myths and fears surrounding menopause by providing women with easy-to-grasp, reliable information, Turning Point helps women retain the peace of mind--and sense of humor--that can make menopause a healthy experience and allow women to move confidently into the second half of life.

Fetal development in the mouse is routinely and increasingly utilized for advancing translational research and medical innovation for human obstetrical care. This is the first and only manual to provide necessary content on how this should be handled for accurate and effective data collection. Detailed descriptions and examples demonstrate how researchers and clinicians can use murine fetal and obstetrical data to improve future human applications in diseases such as infertility, recurrent pregnancy loss, intrauterine fetal growth restriction, placental insufficiency, and intrauterine fetal demise, as well as organ-specific developmental disease.

"Advanced Analysis of Motor Development" explores how research is conducted in testing major issues and questions in motor development. It also looks at the evolution of research in the field, its current status, and possible future directions. This text is one of the few to examine motor development models and theories analytically while providing a context for advanced students in motor development so they can understand current and classic research in the field.

Traditionally, graduate study in motor development has been approached through a compilation of readings from various sources. This text meets the need for in-depth study in a more cohesive manner by presenting parallels and highlighting relationships among research studies that independent readings might not provide. In addition, "Advanced Analysis of Motor Development" builds a foundation in the theories and approaches in the field and demonstrates how they drive contemporary research in motor development.

A valuable text for graduate students beginning their own research projects or making the transition from student to researcher, this text focuses on examining and interpreting research in the field. Respected researchers Haywood, Roberton, and Getchell explain the history and evolution of the field and articulate key research issues. As they examine each of the main models and theories that have influenced the field, they share how motor development research can be applied to the fields of physical education, special education, physical therapy, and rehabilitation sciences.

With its emphasis on critical inquiry, "Advanced Analysis of Motor Development" will help students examine important topics and questions in the field in a more sophisticated manner. They will learn to analyze research methods and results as they deepen their understanding of developmental phenomena. For each category of movement skills covered (posture and balance, foot locomotion, ballistic skills, and manipulative skills), the authors first offer a survey of the pertinent research and then present an in-depth discussion of the landmark studies. In analyzing these studies, students will come to appreciate the detail of research and begin to explore possibilities for their own future research. Throughout the text, special elements help students focus on analysis. Tips for Novice Researchers sidebars highlight issues and questions raised by research and offer suggestions for further exploration and study. Comparative tables detail the differences in the purpose, methods, and results of key studies to help students understand not only what the studies found but also the relevance of those findings.

With "Advanced Analysis of Motor Development," readers will discover how research focusing on the major issues and central questions in motor development is produced and begin to conceptualize their own research. Readers will encounter the most important models and theories; dissect some of the seminal and recent articles that test these models and theories; and examine issues such as nature and nurture, discontinuity and continuity, and progression and regression. "Advanced Analysis of Motor Development" will guide students to a deeper understanding of research in life span motor development and enable them to examine how the complexities of motor development can be addressed in their respective professions.

Die medizinische Behandlung der ungewollten Kinderlosigkeit wird hierzulande nach wie vor mit einer Mischung aus Interesse am medizinisch-technischen Fortschritt und Sorge uber die mogli- cherweise nicht mehr kalkulierbaren Risiken dieses Fortschrittes betrachtet. Die Reaktionen reichen dabei von der implizi ten Gleichsetzung konkreter Formen der Reproduktionsmedizin mit den fiktiven Verhaltnissen in der 'Schonen Neuen welt'1, bis hin zu Einschatzungen, wonach sich die Reproduktionsmedizin in naher Zukunft als ein unverzichtbares Instrument bei der Bekampfung eines langandauernden Bevolkerungsruckganges in der BRD erweisen 2 werde. Auch wenn sich in den letzten 5-10 Jahren das Interesse der Offentlichkeit verstarkt den verschiedenen Formen der medizini- 3 schen Behandlung ungewollter Kinderlosigkeit zugewandt hat, so scheint mit diesem verstarkten Interesse kein Anstieg der Anzahl Der Vergleich des heutigen Potentials der Reproduk- tionsmedizin mit den Schilderungen der industriellen Erzeugung von Menschen in A. Huxleys Roman "Schone Neue Welt" gehort zu den Standardbildern in weiten Teilen der Literatur uber die medizinische Behandlung der ungewollten Kinderlosigkeit. So z.B. auch bei: Hirsch, G. und Eberbach W. (1987): Auf dem Weg zum kunstlichen Leben - Retortenkinder, Leihmutter, pro- grammierte Gene Basel, Boston, Stuttgart. S.31ff. 2 So ein Reproduktionsmediziner in der Fernsehsendung 'Explosiv' (RTL 22.5.'91). 3 Man denke z. B. nur an die Kontroversen im Zuge der Erarbeitung des Embryonenschutzgesetzes, an die Richt- linien zur Durchfuhrung der In-vitro-Fertilisation der Bundesarztekammer, an die Initiativen auf dem 56.