From contraception to cloning and pregnancy to populations, reproduction presents urgent challenges today. This field-defining history synthesizes a vast amount of scholarship to take the long view. Spanning from antiquity to the present day, the book focuses on the Mediterranean, western Europe, North America and their empires. It combines history of science, technology and medicine with social, cultural and demographic accounts. Ranging from the most intimate experiences to planetary policy, it tells new stories and revises received ideas. An international team of scholars asks how modern 'reproduction' - an abstract process of perpetuating living organisms - replaced the old 'generation' - the active making of humans and beasts, plants and even minerals. Striking illustrations invite readers to explore artefacts, from an ancient Egyptian fertility figurine to the announcement of the first test-tube baby. Authoritative and accessible, Reproduction offers students and non-specialists an essential starting point and sets fresh agendas for research.

The Fourth Edition of Knobil & Neill will continue to serve as a reference aid for research, to provide the historical context to current research, and most importantly as an aid for graduate teaching on a broad range of topics in human and comparative reproduction. In the decade since the publication of the last edition, the study of reproductive physiology has undergone monumental changes. Chief among these advances are in the areas of stem cell development, signaling pathways, the role of inflammation in the regulatory processes in the various tissues, and the integration of new animal models which have led to a greater understanding of human disease. This new edition will seek to synthesize all of this new information at the molecular, cellular, and organismal levels of organization and present modern physiology a more understandable and comparative context.
*The leading comprehensive work on the physiology of reproduction
*Edited and authored by the world's leading scientists in the field
*Is a synthesis of the molecular, cellular, and organismic levels of organization
*Bibliogrpahics of chapters are extensive and cover all the relevant literature

Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

The 1990s marked a new era in family formation. Increased access to donor sperm enabled single women and lesbian couples to create their families on their own terms, outside the bounds of heterosexual married relationships. However, emerging "alternative" families were not without social and political controversy. Women who chose to have children without male partners faced many challenges in their quest to have children. Despite current wider social acceptance of single people and same sex couples becoming parents, many of these challenges continue. In Romancing the Sperm, Diane Tober explores the intersections between sperm donation and the broader social and political environment in which "modern families" are created and regulated. Through tangible and intimate stories, this book provides a captivating read for anyone interested in family and kinship, genetics and eugenics, and how ever-expanding assisted reproductive technologies continue to redefine what it means to be human.

'A big-picture forecast of how medicine stands on the threshold of a revolution that will radically change all of our lives' The Times Welcome to a revolution in the science of you! This landmark new book from award-winning scientist Daniel M. Davis explores the future of the human body. Imagine taking drugs to help you acquire new skills, or knowing years in advance the precise likelihood of developing specific cancers, or following a diet and health regime tailored to your microbiome, or even having continuous monitoring of your body's workings and well-being. Written by an award-winning scientist, this landmark book shows how these radical and disconcerting possibilities have been made real. It is at once a gripping drama of scientific ingenuity, discovery and collaboration, and a vision of the human body of dizzying complexity and wonder. 'The startling new discoveries...are radically altering our understanding of how we function and what our future holds' BRIAN COX 'Thrilling' BILL BRYSON 'Brilliant' TIM SPECTOR 'Extraordinary' ALICE ROBERTS

The latest edition of An Atlas of Gynecologic Oncology continues its coverage of the innovative techniques in investigation and surgery on the brink of becoming established as part of the gynecologic surgeon's repertoire, now including the exciting developments in uterine transplantation.

This valuable reference work provides a synthesis of the latest knowledge about the acrosomatic reaction of human sperm. The acrosomatic reaction, which is a fundamental step in the process of fertilisation, is examined on both the fundamental and clinical levels. Three very recent aspects are also dealt with: what happens to the acrosome during intracytoplasmic microinjections, the usefulness of screening spermatozoa that have completed their acrosomatic reaction, and the development of contraception by a vaccine that targets one of the proteins of the acrosome. International Symposium, Collioure, France, September 1995.

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosalvez and Jose A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

Fertility is one of the major health and wellbeing issues for modern women, and Emma Cannon's Total Fertility offers clear, warm and supportive advice to help you on your own unique fertility journey. This book will help you get pregnant now, whether you are going for natural or assisted conception, and also focus on fertility preservation to help you stay fertile longer so you can get pregnant in the future. Emma Cannon answers the many nagging questions women have about fertility and conception; questions such as: How can I get a sense of my fertility? Can I preserve my fertility? When exactly should we be having sex? Does my diet really matter? Does stress lower my chances of conceiving? What exercise should I be doing? Reducing stress and approaching fertility with a calm and positive attitude is central to her approach to getting pregnant, so Emma also helps you develop a 'fertile mindset' with a toolbox of simple suggestions to cultivate emotional wellness for your particular fertility 'type'. Written in Emma's trademark optimistic, warm and non-judgmental tone, Total Fertility is a book for anyone who is thinking - or has ever thought of - getting pregnant.

Making a Good Life takes a timely look at the ideas and values that inform how people think about reproduction and assisted reproductive technologies. In an era of heightened scrutiny about parenting and reproduction, fears about environmental degradation, and the rise of the biotechnology industry, Katharine Dow delves into the reproductive ethics of those who do not have a personal stake in assisted reproductive technologies, but who are building lives inspired and influenced by environmentalism and concerns about the natural world's future. Moving away from experiences of infertility treatments tied to the clinic and laboratory, Dow instead explores reproduction and assisted reproductive technologies as topics of public concern and debate, and she examines how people living in a coastal village in rural Scotland make ethical decisions and judgments about these matters. In particular, Dow engages with people's ideas about nature and naturalness, and how these relate to views about parenting and building stable environments for future generations. Taking into account the ways daily responsibilities and commitments are balanced with moral values, Dow suggests there is still much to uncover about reproductive ethics. Analyzing how ideas about reproduction intersect with wider ethical struggles, Making a Good Life offers a new approach to researching, thinking, and writing about nature, ethics, and reproduction.

The scientific study of aging is a relatively nascent field of inquiry. Although philosophic and literary reflections on what it means to grow older appear in the earliest historical records, the systematic study of aging began in earnest about a century ago. Scholarly interest in the topic has accelerated in recent decades, due in part to rapid population aging in developed nations. As a result, the study of aging has been incorporated into many disciplines, emphasizing concepts, theories, and methods to elucidate the antecedents and consequences of growing older. Although each discipline has key concepts and empirical generalizations about aging, there is little agreement across disciplines about the intellectual core of gerontology. Each discipline brings its own intellectual heritage and perspective to the study of aging, but the question posed by author Ken Ferraro is whether there is an emergent perspective or way of thinking about aging that transcends the disciplines. Biologists, psychologists, and sociologists may claim an interest in gerontology, but do they have a common image of aging or a set of principles to guide their research? Do they share a paradigm-a fundamental image of aging-that incorporates concepts and empirical generalizations from multiple disciplines? And when disciplinary approaches to gerontology clash, which approach or conceptualization of aging is likely to emerge as part of the paradigm? Although biologists, psychologists, and social scientists share an interest in the study of aging, they are distinctive in how they conduct their research. The Gerontological Imagination provides an integrative paradigm of aging that makes it the first book to identify intellectual common ground among scholars studying aging. Ferraro identifies an underlying set of principles that constitute a paradigm for the study of aging: causality, life course analysis, multifaceted change, heterogeneity, accumulation processes, and ageism. The proposed paradigm provides an efficient way to identify and interpret essential ideas, findings, models, and theories across multiple disciplines that study aging.

Written by world-leading fertility experts and edited by mums who have undertaken multiple cycles of IVF and know what it takes to succeed, this guide advises you on the entire IVF process and how to maximise your chances of success . All IVF topics are covered, from how to choose your fertility clinic, to understanding the stages of an IVF cycle, to how to prepare yourself physically and emotionally for the treatment. * Looks at how to optimise your nutrition and how to improve egg and sperm quality * Examines the growing trends of egg freezing and donor-assisted IVF * Shares real-life stories of a variety of IVF journeys and their inspiring outcomes * Includes key contributions from the Human Fertilisation and Embryology Authority (HFEA), the UK's independent regulator for fertility treatment and research IVF: All You Need to Know is an essential handbook for couples and individuals who are considering IVF, who want to find out what's involved, and who want to be as well prepared as they can be. It is also for those who may have already tried IVF, have experienced failed cycles and want to boost their chances of success next time around.

'Some people improve mentally with age - here's how you can be one of them.' Mail on Sunday 'More than a game-changer, this book's a no-brainer for anyone who wants to optimise their brain.' Piers Morgan With a new chapter on Covid and the Brain, this is the definitive guide to keeping your brain healthy for a long and lucid life, by one of the world's leading scientists in the field of brain health and ageing. The brain is our most vital and complex organ. It controls and coordinates our actions, thoughts and interactions with the world around us. It is the source of personality, of our sense of self, and it shapes every aspect of our human experience. Yet most of us know precious little about how our brains actually work, or what we can do to optimise their performance. Whilst cognitive decline is the biggest long-term health worry for many of us, practical knowledge of how to look after our brain is thin on the ground. In this ground-breaking new book, leading expert Professor James Goodwin explains how simple strategies concerning exercise, diet, social life and sleep can transform your brain health paradigm, and shows how you can keep your brain youthful and stay sharp across your life. Combining the latest scientific research with insightful storytelling and practical advice, Supercharge Your Brain reveals everything you need to know about how your brain functions, and what you can do to keep it in peak condition.

'Open, honest, straight talking on mental health and motherhood.' - Tik Tok's Dr Julie 'I absolutely love it - it doesn't matter who you are, what you've been through and how much you've changed - there is always room for growth'. - Ant Middleton 'This book will become your bible.' - Gaby Roslin, Virgin Radio In GROW, Sunday Times bestselling author Frankie Bridge opens up about her journey with her maternal mental health. Part narrative exploration, part first aid manual for mothers this book will discuss the hidden growing pains which take place when you become a parent. Its chapters cover the HOW TOs, WHAT IFs?, WILL Is? and WHY DOs? anxious questions all mothers ask themselves when they believe they are doing it wrong whilst also offering a brutally honest account of how hard it can be to grow a baby and raise a child whilst you are still growing into yourself. The book will combine Frankie's mental health journey into motherhood with the notes of psychologist, Maleha Khan, who will unpack the problems she experienced as she became a mother. It will also include additional guidance and parental advice from the UK's leading paediatrician Dr Ed Abrahamson. Fans of OPEN: 'Brave and beautiful... a first aid manual for your mind.' - Adam Kay, bestselling author of This is Going To Hurt 'Very readable. Very relatable. Intensely moving but also full of practical advice.' - Alastair Campbell

Any events that challenge the survival of living organisms may be classified as stressors. These stressors could include, for example, lack of food, increased population pressure, predatory pressure, climatic events or in the case of humans, loss of a loved one, lack of financial security or uncertainty in the future. Although most physiological systems are affected by stress, those systems that regulate reproductive physiology and behaviour are the most sensitive. All multicellular organisms show a stress related effect on reproduction, although the more complex organisms, such as mammals, have the most complex effects.

The objective of this book is to provide a comparative analysis of the mechanisms by which stress regulates reproduction exploring the evolution of stress perceiving systems from the simplest organisms to humans. Taking an integrated approach, utilising a genes-to-environment overview, the book examines the stressors that occur at all levels of organisation. These theories are used to examine and explain human and animal reproductive behaviour and physiology under stressful conditions providing a well-written, concise introduction to this important subject.

Random Families is about the unprecedented families that have grown up at the intersection of new reproductive technologies, social media, and the human desire for belonging. Children of the same donor and their families, with the help of the internet, can now locate each other and make contact. Based on over 350 interviews with children (ages 10-28), their parents and related donors from all over the U.S., Random Families chronicles the chain of choices that couples and single mothers make from what donor to use to how to participate (or not) in donor sibling networks. Children reveal their understanding of a donor, the donor's spot on the family tree and the meaning of their donor siblings. Through rich first-person accounts of network membership, the book illustrates how these extraordinary relationships-woven from bits of online information and shared genetic ties-are transformed into new possibilities for kinship. Random Families offers down-to-earth stories from real families to highlight just how truly distinctive these contemporary new forms of family are.

One in six couples have problems conceiving and many more suffer the pain of miscarriage, which FIT FOR FERTILITY also addresses. Much of the advice they're given is misleading or negative and IVF is often presented as the only option. In fact, it's been shown that an integrated approach to fertility treatment achieved the same success rates as IVF, without medical intervention, worry and expense. This is Michael's approach and is based on his hugely successful Fit for Fertility programme that combines changes to lifestyle, good nutrition and complementary therapies. FIT FOR FERTILITY will allow the reader to self diagnose and tailor their programme according to their needs. It is infused with Michael's up-beat philosophy and builds on his inspiring work to promise a genuine chance of success.

How might we better understand our travels through Grandmotherland? In this lively exploration, an experienced child psychotherapist draws together a wide range of perspectives on the role and experience of grandmothers. Judith Edwards looks back to the past and forward to the future, while being rooted in the reality of the modern grandmother’s life. We meet ‘good’ grannies, ‘bad’ grannies, and all those in between, as well as women who decided to be agents of transmission in other ways than passing on their DNA. Our guide looks at how the behaviour of the grandmother is affected by personality, culture, tradition and ‘norms’ and considers how psychoanalytic insights may help us understand this territory of life.

The Year Book of Neonatal and Perinatal Medicine brings you abstracts of the articles that reported the year's breakthrough developments in neonatal and perinatal medicine, carefully selected from more than 500 journals worldwide. Expert commentaries evaluate the clinical importance of each article and discuss its application to your practice. There's no faster or easier way to stay informed Chapters in this annual cover the most current information on all aspects of neonatal and perinatal medicine from genetics to labor and delivery to issues related to many key bodily systems (heart, respiratory, nervous system, etc.) of newborns. Other topics for 2004 include neurology, gastroenterology and nutrition, medical disorders of pregnancy, fetal evaluation, and neonatal behavior.

Thirty-five years after its initial success as a form of technologically assisted human reproduction, and five million miracle babies later, in vitro fertilization (IVF) has become a routine procedure worldwide. In Biological Relatives, Sarah Franklin explores how the normalization of IVF has changed how both technology and biology are understood. Drawing on anthropology, feminist theory, and science studies, Franklin charts the evolution of IVF from an experimental research technique into a global technological platform used for a wide variety of applications, including genetic diagnosis, livestock breeding, cloning, and stem cell research. She contends that despite its ubiquity, IVF remains a highly paradoxical technology that confirms the relative and contingent nature of biology while creating new biological relatives. Using IVF as a lens, Franklin presents a bold and lucid thesis linking technologies of gender and sex to reproductive biomedicine, contemporary bioinnovation, and the future of kinship.

Guest edited by Bonnie Joe, this issue of MRI Clinics covers breast screening protocols, imaging the newly diagnosed cancer patient, imaging to monitor response to therapy, breast MR spectroscopy, and more.

This issue of the Obstetrics and Gynecology Clinics covers the Medical and Surgical Management of Common Fertility Issues. Articles include Infertility Evaluation, Ovulation Induction, and problems such as fibroids, endometriosis, and ectopic pregnancy.

As our understanding of the human body broadens, so does the need for a comprehensive text that encompasses all aspects of human development. Essential Human Development is a great course companion that focuses on the human life cycle, ideal for the undergraduate student new to these fields, or for qualified practitioners looking for a reference guide. Featuring key information points and self-test assessments in each chapter, the book is organised in an accessible manner, beginning with fertilisation and embryology, then moving on to obstetric medicine, neonatal care and child health, with the final section exploring gynaecological medicine. Ensuring that information is placed in context to aid understanding, Essential Human Development is the perfect support for the modern medical school curriculum, as well as a vital reminder of the core information needed whilst on a women or child health clinical placement.

Now in a completely revised and expanded fourth edition, including two new chapters, this user-friendly textbook offers a succinct overview of both the medical and surgical management of reproductive disorders, as well as coverage of associated imaging modalities. Included here are updated chapters on major reproductive endocrinology and infertility issues, such as polycystic ovary syndrome (PCOS), pubertal disorders, amenorrhea, menopause, management of endometriosis and fibroids (including interventional radiology), laboratory and clinical aspects of assisted reproductive technologies (ART), imaging modalities such as ultrasonography and sonohysterography, hysteroscopic and laparoscopic techniques, an expansion of female infertility and fertility, preimplantation diagnosis and screening, osteoporosis, and contraception and sterilization. Chapters new to this edition discuss third-party reproduction and uterine transplantation. In addition, chapters opens with a list of bulleted key points and end with multiple choice review questions, and most include vibrant clinical case material to illustrate important concepts. Residents, fellows, and new clinicians in obstetrics and gynecology interested in reproductive endocrinology and infertility will find this fourth edition of Clinical Reproductive Medicine and Surgery: A Practical Guide a valuable and focused reference.