With the ever-increasing rise in life expectancy, there is an urgent need to improve our understanding of the relationship between ageing and the pathogenesis of age-related diseases in order to identify more effective means of prevention, amelioration and management of such diseases. In addition, there is a need to reduce the social and economic impact of the ageing population. Age-related morbidity and mortality vary dramatically among individuals; this book focusses on individual differences in susceptibility to age-related disorders.

It contains contributions from leading experts in the field on topics such as:
age-related pathology in the brain, age-related processes in stem cells, and age-related effects on the immune system and in bone, muscle and cardiovascular tissue. For all those with an interest in the biology of ageing, this is compulsory reading.

Meet Woody. Former journalist. Die-hard Oasis fan. High energy. Low sperm count. Training to be a vicar. Obviously. Matt Woodcock's frank, funny real-life diaries reveal what it was like for him to train as a vicar while struggling against all odds to become a father. In them he lays bare his joys and struggles as he attempts to reconcile his calling as a vicar with his life as a party-loving journalist, footie-freak and incorrigible extrovert. Becoming Reverend is a compelling and original account of how faith can work in the midst of a messy life, combining family, fertility, faith and friendship with the story of a divine - but unlikely - calling.

This issue of Radiologic Clinics of North America focuses on Imaging of the Reproductive Age Female, and is edited by Dr. Liina Poder. Articles will include: Imaging Safety and Technical Considerations in the Reproductive Age Female; Imaging of Infertility: Hysterosalpingograms to MRI; Imaging Spectrum of Benign Uterine Disease and Treatment Options; Imaging of Benign Adnexal Disease; Imaging Spectrum of Endometriosis (Endometriomas to Deep Infiltrative Endometriosis); Imaging of The Female Pelvic Floor: Current Implications and New Horizons; Imaging of Acute Pelvic Pain: Nonpregnant; Imaging of Acute Pelvic Pain: Pregnant (ectopic and first trimester viability updated); Nonfetal Imaging During Pregnancy: Acute Abdomen/Pelvis; Nonfetal Imaging During Pregnancy: Placental Related Disease; Imaging of Gynecologic Malingancy in a Reproductive Age Female: Fertility Sparing; Imaging of Gynecologic Malignancy in A Reproductive Age Female: Cancer During Pregnancy; Imaging of Post/Peripartum Complications; Role of Interventional Procedures in Obstetrics and Gynecology, and more!

Dieser Buchtitel ist Teil des Digitalisierungsprojekts Springer Book Archives mit Publikationen, die seit den Anfangen des Verlags von 1842 erschienen sind. Der Verlag stellt mit diesem Archiv Quellen fur die historische wie auch die disziplingeschichtliche Forschung zur Verfugung, die jeweils im historischen Kontext betrachtet werden mussen. Dieser Titel erschien in der Zeit vor 1945 und wird daher in seiner zeittypischen politisch-ideologischen Ausrichtung vom Verlag nicht beworben.

Rationalization is concerned with making the most effective use of the resources available. In many places where this process is taking place it is plagued with public opposition and misunderstanding. Hitherto rationalization in the acute care sector has primarily been concerned with closing sites closing beds moving beds between services and moving beds from one site to another. This book discusses the need for rationalization in the context of health service reforms and future strategy. It considers recent changes in the health service the case for rationalization health care needs the role of public relations the future of the acute care hospital site and facilities appraisal and the costs of rationalization. The text is essential reading for managers and clinicians involved in acute care services non-executive members of boards and trusts and students of health services management.

Few recent technologies have attracted as much attention as In Vitro Fertilization (IVF), a technique in which ova are fertilized in a glass dish and transferred to the prospective mother. Despite a large body of literature and much recent publicity on the ethics of new re-productive technologies, however, we are far from understanding what actually goes on in the nation's 138 in vitro fertilization centers, and even farther from possessing a clear public policy regarding this controversial technology. In this book the author examines two different, and often opposing worlds of in vitro fertilization: the public's political, legal and ethical concerns surrounding the technique, and the personal, pragmatic world of the individual patients who come to the centers seeding a cure for infertility. The crux of this analysis revolves around the intersection, and sometimes the antagonism, between these two worlds. While use of the centers is growing extremely fast, there is an absence of any federal-level policy to monitor this technique. To fill this vacuum, individual practitioners of IVF and other new reproductive technologies. The author investigates the current effects of these guidelines in interviews with physicians, scientists, policy makers, and patients at IVF centers, and argues that in this case, the public policy we implement should take its direction from the self-regulation that is already occurring on a local level and which is so well-developed that it has in effect taken the place of a formal federal policy. For all those interested in, or contemplating the rapidly growing field of in vitro fertilization, this is an objective analysis which answers many perplexing questions.

Late aging associated changes in alcohol sensitivity, neurobehavioral function, and neuroinflammation, Volume 148, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

Clinicians and scientists are increasingly recognising the importance of an evolutionary perspective in studying the aetiology, prevention, and treatment of human disease; the growing prominence of genetics in medicine is further adding to the interest in evolutionary medicine. In spite of this, too few medical students or residents study evolution. This book builds a compelling case for integrating evolutionary biology into undergraduate and postgraduate medical education, as well as its intrinsic value to medicine. Chapter by chapter, the authors - experts in anthropology, biology, ecology, physiology, public health, and various disciplines of medicine - present the rationale for clinically-relevant evolutionary thinking. They achieve this within the broader context of medicine but through the focused lens of maternal and child health, with an emphasis on female reproduction and the early-life biochemical, immunological, and microbial responses influenced by evolution. The tightly woven and accessible narrative illustrates how a medical education that considers evolved traits can deepen our understanding of the complexities of the human body, variability in health, susceptibility to disease, and ultimately help guide treatment, prevention, and public health policy. However, integrating evolutionary biology into medical education continues to face several roadblocks. The medical curriculum is already replete with complex subjects and a long period of training. The addition of an evolutionary perspective to this curriculum would certainly seem daunting, and many medical educators express concern over potential controversy if evolution is introduced into the curriculum of their schools. Medical education urgently needs strategies and teaching aids to lower the barriers to incorporating evolution into medical training. In summary, this call to arms makes a strong case for incorporating evolutionary thinking early in medical training to help guide the types of critical questions physicians ask, or should be asking. It will be of relevance and use to evolutionary biologists, physicians, medical students, and biomedical research scientists.