Herbal Bioactive-Based Drug Delivery Systems: Challenges and Opportunities provides a wide-ranging, in-depth resource for herbal bioactives, including detailed discussion of standardization and regulations. The book first explores specific drug delivery systems such as gastrointestinal, ocular, pulmonary, transdermal, and vaginal and rectal. It then discusses novel applications for nano, cosmetics, nutraceuticals, wound healing and cancer treatment. Finally, there is a section focusing on standardization and regulation which includes an enhancement of properties. This book is an essential resource for pharmacologists, pharmaceutical scientists, material scientists, botanists, and all those interested in natural products and drug delivery systems developments.

Guests directly account for over 50% of resource use in hotels and as much as 90% in self-catering accommodation. They are quite simply the most significant factor contributing to hospitality's ongoing carbon emissions. Given the targets to reduce carbon emissions by 66% by the year 2030, it is imperative that practical solutions for the accommodation sector are created and applied fast. 'How to Create Sustainable Hospitality: a handbook for guest participation' is the first text to demonstrate how to actively persuade guests to participate in achieving sustainable hospitality. Practitioners and commentators have tended to criticise guests, believing they won't "sacrifice" while on holiday. However, social trends show there is increasing consumer expectations for more sustainable services, e.g. reduction of food waste, elimination of single serve plastic, as well as firm evidence that consumption is not linked to guest happiness. The opportunity is therefore to design experiences which deliver better hospitality by inviting guests to apply saving behaviours that do not mean they will have a less enjoyable experience. Based on 16 years personally delivering sustainable hospitality experiences face to face with guests and conducting the first hard research on guest engagement at a variety of sites in Australia and Europe (from 1000-bedroom hotels and B&Bs to self-contained holiday homes and timeshare lodges), the author presents a tried and tested five step methodology on how to directly, effectively and successfully involve guests to conserve resources. This presents a new paradigm for tourism. 'How to Create Sustainable Hospitality: a handbook for guest participation' presents a clearly written, jargon-free, practical solution and: * Is the first book to focus on guests as an active and critical component in sustainable consumption and production at their holiday or business accommodation; * Introduces a five-step methodology on how to directly and effectively involve guests in saving energy and water, reducing food waste and cutting carbon. It delivers a practical solution that has been successfully applied to achieve a fast ROI with scientifically measured savings; * Uses social practice theory to describe why people do not save resources and how we can better design hospitality experiences * Uses persuasive theory to explain how to communicate with guests and by so doing increase stay satisfaction, 'delight' and brand reputation; * Includes hundreds of case examples and scientific research to illustrate how the theories works in practice; * Explains "how" to change - not just the need for change. Part of the Responsible Tourism Series edited by Harold Goodwin, Director of Responsible Tourism, Institute of Place Management at Manchester Metropolitan University and John Swarbrooke, Associate Dean-International, Plymouth Global, Plymouth University, UK

It is almost impossible to keep up with the pace and direction in which business and technology are moving today.

ARTIFICIAL INTELLIGENCE. AUTOMATION. BLOCKCHAIN. BIG DATA. INTERNET OF THINGS. THE FOURTH INDUSTRIAL REVOLUTION.

Who actually knows what any of these concepts mean for their business, much less how to integrate them? Things are moving at a faster pace than ever before and trying to keep up has become intimidating and overwhelming. It’s tempting to bury your head in the sand than try to make head or tail of it all. But none of the buzzwords actually matter! You don’t have to jump aboard every single change and adjustment in the market, or trade in your suit for a T-shirt, jeans and sneaker combo. If you have the right context, it’s a lot simpler to understand and use technological shifts as an opportunity to transform your business.

Tech Adjacent is about understanding the principles of tech and its pace, hearing the footsteps of where it might be going, knowing how disruption and innovation work tangibly and, most importantly, leveraging it for your individual exponential success. Innovation is contextual, so while Uber, Airbnb and Facebook are grandiose Silicon Valley success stories, they have little relevance in our own market. This book shares stories and case studies of African businesses, exposing who is getting disrupted as we speak and why, as well as how new companies are leading the next wave of growth. Mushambi Mutuma’s experience and expertise in both business and as a tech entrepreneur give real-life context to rapid change, unlocking future opportunities and offering tools to predict where your audience and industry are heading. He sells no big ideas, but genuinely shares his unique perspectives and know-how to help whoever he can in the process.

Tech Adjacent isn’t just another book on growing your business in 100 days, nor is it dry academic theory. It is the guidebook for not only surviving but excelling in a world of exponential growth. Whether you are a start-up entrepreneur or a corporate executive, this guide is a must for both present and future leaders.

Process Systems Engineering for Pharmaceutical Manufacturing: From Product Design to Enterprise-Wide Decisions, Volume 41, covers the following process systems engineering methods and tools for the modernization of the pharmaceutical industry: computer-aided pharmaceutical product design and pharmaceutical production processes design/synthesis; modeling and simulation of the pharmaceutical processing unit operation, integrated flowsheets and applications for design, analysis, risk assessment, sensitivity analysis, optimization, design space identification and control system design; optimal operation, control and monitoring of pharmaceutical production processes; enterprise-wide optimization and supply chain management for pharmaceutical manufacturing processes. Currently, pharmaceutical companies are going through a paradigm shift, from traditional manufacturing mode to modernized mode, built on cutting edge technology and computer-aided methods and tools. Such shifts can benefit tremendously from the application of methods and tools of process systems engineering.

Systems Evolutionary Biology: Biological Network Evolution Theory, Stochastic Evolutionary Game Strategies, and Applications to Systems Synthetic Biology discusses the evolutionary game theory and strategies of nonlinear stochastic biological networks under random genetic variations and environmental disturbances and their application to systematic synthetic biology design. The book provides more realistic stochastic biological system models to mimic the real biological systems in evolutionary process and then introduces network evolvability, stochastic evolutionary game theory and strategy based on nonlinear stochastic networks in evolution. Readers will find remarkable, revolutionary information on genetic evolutionary biology that be applied to economics, engineering and bioscience.

Marketing Tourism in South Africa 6e offers a solid foundation in marketing theory applied to the unique context of the tourism industry in South Africa. This updated edition is a definitive source for universities, universities of technology and colleges where courses in Tourism Marketing and Event Marketing are offered. Marketing Tourism in South Africa 6e is written in a simple and concise style to appeal to both tourism students and practitioners. The text familiarises the reader with the tourism industry in South Africa its statistics, trends, main organisations and role-players.

Understanding Sectoral Determination 14: Hospitality Sector forms part of the Juta’s Pocket Companions series, to complement the highly successful Juta’s Pocket Statutes series.

Chapter 8 of the Basic Conditions of Employment Act 75 of 1997 allows the Minister of Labour to promulgate minimum conditions of employment for employees in specific sectors or areas, in the form of Sectoral Determinations. Sectoral Determination 14 sets out minimum conditions of employment in the South African Hospitality sector, a sector employing over 1 000 000 people in various positions in hotels, bed-and-breakfast establishments, guest houses and farms, lodges, catering businesses, fast food outlets and restaurants.

This book presents a non-legalistic commentary on the specific minimum conditions of employment applicable to persons employed in South Africa in the Hospitality sector. It includes the Bargaining Council Main Agreement for the ‘Bargaining Council for the Restaurant, Catering and Allied Trades’, which is applicable to certain magisterial districts in the Gauteng Province. The key provisions of the Sectoral Determination are covered in a systematic manner, with Key Point summaries at the end of each section.

Big Data and Smart Service Systems presents the theories and applications regarding Big Data and smart service systems, data acquisition, smart cities, business decision-making support, and smart service design. The rapid development of computer and Internet technologies has led the world to the era of Big Data. Big Data technologies are widely used, which has brought unprecedented impacts on traditional industries and lifestyle. More and more governments, business sectors, and institutions begin to realize data is becoming the most valuable asset and its analysis is becoming the core competitiveness.

Digital and social media are increasingly integrated into the dynamics of protest movements around the world. They strengthen the mobilization power of movements, extend movement networks, facilitate new modes of protest participation, and give rise to new protest formations. Meanwhile, conventional media remains an important arena where protesters and their targets contest for public support. This book examines the role of the media - understood as an integrated system comprised of both conventional media institutions and digital media platforms - in the formation and dynamics of the Umbrella Movement in Hong Kong. For 79 days in 2014, Hong Kong became the focus of international attention due to a public demonstration for genuine democracy that would become known as the Umbrella Movement. During this time, twenty percent of the local population would join the demonstration, the most large-scale and sustained act of civil disobedience in Hong Kong's history - and the largest public protest campaign in China since the 1989 student movement in Beijing. On the surface, this movement was not unlike other large-scale protest movements that have occurred around the world in recent years. However, it was distinct in how bottom-up processes evolved into a centrally organized, programmatic movement with concrete policy demands. In this book, Francis L. F. Lee and Joseph M. Chan connect the case of the Umbrella Movement to recent theorizations of new social movement formations. Here, Lee and Chan analyze how traditional mass media institutions and digital media combined with on-the-ground networks in such a way as to propel citizen participation and the evolution of the movement as a whole. As such, they argue that the Umbrella Movement is important in the way it sheds light on the rise of digital-media-enabled social movements, the relationship between digital media platforms and legacy media institutions, the power and limitations of such occupation protests and new "action logics," and the continual significance of old protest logics of resource mobilization and collective action frames. Through a combination of protester surveys, population surveys, analyses of news contents and social media activities, this book reconstructs a rich and nuanced account of the Umbrella Movement, providing insight into numerous issues about the media-movement nexus in the digital era.

This book is the result of over ten years of field research across Zambia. It covers the production and diverse uses of wood and non-wood forest products in different parts of Zambia. Although a short format, it is a multi-contributed work. It starts an overview of the forestry sector, and covers more specific areas like production, markets and trade of wood and non-wood products; the role of non-wood forest products in the livelihood of the local population, the contribution of the forestry sector to Zambia's overall economy and reviews of efforts to strategically utilize these resources for local economic, and sustainable, development.

In March 2011 the Fukushima nuclear power plant (NPP) in Japan was hit by an earthquake and subsequent tsunami which resulted in the release of significant amounts of radioactive material. The incident led to the suspension of nuclear programmes by a number of countries. This book provides a definitive account of the accident.

Hier is dit nou! Riaan klim uit die TV-kas! Sy langverwagte outobiografie met die ware Riaan gaan elke mens laat regop sit.

Gou word die leser in hierdie kostelike, gemaklike en informatiewe biografie ingetrek, sodat jy later absoluut meegevoer word deur die welkome inligting. Dit voel eintlik asof jy vir ete by die Cruywagens genooi is en jy in 'n diep gemakstoel na daardie welluidende mooi stem sit en luister wat op 'n boertige en gesellige manier onthou. Hy bring al vir die afgelope 47 jaar vir ons die nuus in ons huis en lyk sowaar nog presies dieselfde. Vind uit hoekom hy die geloofwaardigste Suid-Afrikaner naas Nelson Mandela is. In hierdie boek wys ons jou wie Riaan werklik is. 'n Familieman wat ‘n passie het vir Afrikaans en wat mal is oor 'n goeie grap.

Hierdie boek gaan jou laat skater van die lag en jou hart laat warm klop na jy dit gelees het.

Therapeutic risk management of medicines is an authoritative and practical guide on developing, implementing and evaluating risk management plans for medicines globally. It explains how to assess risks and benefit-risk balance, design and roll out risk minimisation and pharmacovigilance activities, and interact effectively with key stakeholders.

A more systematic approach for managing the risks of medicines arose following a number of high-profile drug safety incidents and a need for better access to effective but potentially risky treatments. Regulatory requirements have evolved rapidly over the past decade. Risk management plans (RMPs) are mandatory for new medicinal products in the EU and a Risk Evaluation and Mitigation Strategy (REMS) is needed for certain drugs in the US.

This book is an easy-to-read resource that complements current regulatory guidance, by exploring key areas and practical implications in greater detail. It is structured into chapters encompassing a background to therapeutic risk management, strategies for developing RMPs, implementation of RMPs, and the continuing evolution of the risk management field.The topic is of critical importance not only to the pharmaceutical and biotechnology industries, but also regulators and healthcare policymakers.Some chapters feature contributions from selected industry experts.
An up-to-date practical guide on conceiving, designing, and implementing global therapeutic risk management plans for medicinesA number of useful frameworks are presented which add impact to RMPs (Risk Management Plans), together with regional specific information (European Union, United States, and Japan)Acomprehensive guide for performing risk management more effectively throughout a product s life-cycle"

This authoritative and comprehensive book makes the reader familiar with the processes of bringing orphan drugs to the global market. There are between 5,000 and 7,000 rare diseases and the number of patients suffering from them is estimated to be more than 50 million in the US and Europe. Before the orphan drug legislation enacted in the US in 1983, there was a limited interest from industry to develop treatment for very small patient groups. One of the difficulties is, of course, that similar levels of investment are needed from a pharmaceutical company to bring a drug to the market for both small and large patient groups.
The journey from application of an orphan drug designation to a reimbursed market- approved drug is long and many obstacles occur during the journey.
After reading the book, readers will: Understand who the players/stakeholders are in the rare orphan disease field and their specific needs and concerns: patients and patient organizations, researchers and treating physicians within the field, industry, regulatory and reimbursement bodies* Understand the strong partnership between the different players and the various initiatives to improve and increase access to treatment for patients; minimizing the gap between numbers of known diseases, orphan designations, approved drugs and paid drugs.
The book also provides short practical case stories from patients and researchers, as well as representatives from industry and authorities on the challenges they came across in developing orphan drugs or getting access to orphan drugs.
A comprehensive overview of strategy, key activities and considerations of how to bring an orphan drug from concept to the market and make it available to patientsA source of updated information, news and trends for those who are already active in this fast-evolving fieldCovers the global definitions and the criteria for getting an orphan drug designation in, for example, the US and Europe

Research methods can be a daunting topic - Researching Tourism, Leisure and Hospitality for your Dissertation is a unique text that takes away the stress, worry and confusion by providing a step-by-step, user friendly guide to all you need to know to successfully research and compile your dissertation. Researching Tourism, Leisure and Hospitality for your Dissertation provides a discussion of quantitative, qualitative and mixed methods approaches, looking at key differences and similarities. A critical evaluation of these different research approaches is provided and, importantly, a discussion on selecting the appropriate approach(es) for your dissertation, including a discussion and evaluation of mixed methods research. It takes the reader from the initial idea and topics, through to lit reviews, methodology, presenting and analysing results and successfully making conclusions. Unlike other texts available, the text includes case studies based on the author's own research to demonstrate different research approaches and techniques, providing an opportunity for criticism and a discussion on 'learning from mistakes.' Divided into 7 chapters Researching Tourism, Leisure and Hospitality for your Dissertation discusses: * Developing your research topic - including the ethics statement; * Literature review - how to do it and how to get the most from it; * Methodology - which approach (es) are most suitable, with clear links between ontology, epistemology and methodology and how these concepts relate to the actual dissertation; * Presenting Results - how this can be done clearly and coherently * Analysing and Discussing Results - whether they are qualitative, quantitative or mixed methods; * Conclusions: your findings, your limitations and your recommendations. A must-have text for all students on how best to conduct research, compile your findings and to present them in the resulting dissertation. Peter Mason is Professor of Tourism Management, Bedfordshire University, Visiting Professor of Tourism, London South Bank University and has a fractional position as Lecturer, London Metropolitan University.

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology.
A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technologyCase studies are presented in order to facilitate understanding of various concepts in computer-aided applications

Complex raw materials and manufacturing processes mean the textile industry is particularly dependent on good process control to produce high and consistent product quality. Monitoring and controlling process variables during the textile manufacturing process also minimises waste, costs and environmental impact. Process control in textile manufacturing provides an important overview of the fundamentals and applications of process control methods.
Part one introduces key issues associated with process control and principles of control systems in textile manufacturing. Testing and statistical quality control are also discussed before part two goes on to consider control in fibre production and yarn manufacture. Chapters review process and quality control in natural and synthetic textile fibre cultivation, blowroom, carding, drawing and combing. Process control in ring and rotor spinning and maintenance of yarn spinning machines are also discussed. Finally part three explores process control in the manufacture of knitted, woven, nonwoven textiles and colouration and finishing, with a final discussion of process control in apparel manufacturing.
With its distinguished editors and international team of expert contributors, Process control in textile manufacturing is an essential guide for textile engineers and manufacturers involved in the processing of textiles, as well as academic researchers in this field.
Provides an important overview of the fundamentals and applications of process control methodsDiscusses key issues associated with process control and principles of control systems in textile manufacturing, before addressing testing and statistical quality controlExplores process control in the manufacture of knitted, woven, nonwoven textiles and colouration and finishing, with a discussion on process control in apparel manufacturing

Academic and professional publishing represents a diverse communications industry rooted in the scholarly ecosystem, peer review, and added value products and services. Publishers in this field play a critical and trusted role, registering, certifying, disseminating and preserving knowledge across scientific, technical and medical (STM), humanities and social science disciplines. Academic and Professional Publishing draws together expert publishing professionals, to provide comprehensive insight into the key developments in the industry and the innovative and multi-disciplinary approaches being applied to meet novel challenges.
This book consists of 20 chapters covering what publishers do, how they work to add value and what the future may bring. Topics include: peer-review; the scholarly ecosystem; the digital revolution; publishing and communication strategies; business models and finances; editorial and production workflows; electronic publishing standards; citation and bibliometrics; user experience; sales, licensing and marketing; the evolving role of libraries; ethics and integrity; legal and copyright aspects; relationship management; the future of journal publishing; the impact of external forces; career development; and trust in academic and professional publishing.
This book presents a comprehensive review of the integrated approach publishers take to support and improve communications within academic and professional publishing.
Brings together expert publishing professionals to provide an authoritative insight into industry developmentsDetails the challenges publishers face and the leading-edge processes and procedures used to meet themDiscusses the range of new communication channels and business models that suit the wide variety of subject areas publishers work in

Advances in technology, combined with the ever-evolving needs of the global market, are having a strong impact on the textile and clothing sector. The global textile and clothing industry: Technological advances and future challenges provides an essential review of these changes, and considers their implications for future strategies concerning production and marketing of textile products.
Beginning with a review of trends in the global textile industry, the book goes on to consider the impact of environmental regulation on future textile products and processes. Following this, the importance of innovation-driven textile research and development, and the role of strategic technology roadmapping are highlighted. Both the present structure and future adaptation of higher education courses in textile science are reviewed, before recent advances in textile manufacturing technology, including joining techniques, 3D body scanning and garment design and explored in depth. Finally, The global textile and clothing industry concludes by considering automating textile preforming technology for the mass production of fibre-reinforced polymer (FRP) composites.
With its distinguished editor and international team of expert contributors, The global textile and clothing industry: Technological advances and future challenges is an essential guide to key challenges and developments in this industrial sector.
Comprehensively examines the implications of technological advancements and the evolving needs of the global market on the textile and clothing industry and considers their role on the future of textile manufacturingThe importance of innovation-driven textile research and development and the role of strategic technology roadmapping are thoroughly investigatedRecent advances in textile manufacturing technology, including joining techniques, 3D body scanning and garment design and explored in depth

As the global climate changes, scientists anticipate that the distribution of animal populations and disease vectors will expand. In the case of arthropods, such efforts hold immense significance as they have the potential to increase human mortality and suffering from arboviruses above current levels. The 238th American Chemical Society National Meeting and Exposition in Washington, D.C. on August 16-20, 2009, offered an opportunity for researchers to present and discuss new findings in invertebrate repellents research, regulations, and technology development. Recently efforts have been made to understand the role of chemicals in arthropod behavior, and screening programs are starting to incorporate repellency testing into their battery of bioassays. The lack of standardized protocols for measuring and comparison of repellents has remained a significant obstacle in arthropod research. Oftentimes studies report variable measures of success, and comparison of results across studies is not always consistent. Progress in the standardization of arthropod test methods for repellents would be valuable to many groups including academic researchers working in the field, contract labs supplying test results, government research laboratories, regulatory bodies in the process of developing guidelines for product registration, as well as companies looking to invest in new technologies. Perhaps one complicating factor in this process has been that research and technology haven't moved fast enough to meet the demand for effective arthropod repellents. Issues such as pest arthropod resurgence and insecticide/repellent resistance to chemical can create new challenges and add pressure for researchers. The collection of chapters in this book covers a range of applied and basic research on arthropod repellents. An overview of the state of arthropod repellents research is provided at the start. In the chapters that follow, there is a selection of papers demonstrating research on new repellent technologies at different stages of development. The scope of basic and applied research methods described in these chapters on new repellent technologies presents the range of testing that is often necessary to move a repellent technology forward in development. The transition from newly developed technologies to registered products is achieved in perspective of a growing market for natural arthropod repellents. New technologies that are completely developed and have gone through registration need to be accompanied by successful commercialization. The growing market for natural arthropod repellents presents such an example and highlights new opportunities in this area. The concluding chapter discusses the public entomology landscape, past and future opportunities for the development of chemical protectants.

Music and tourism, both integral to the culture and livelihood of the circum-Caribbean region, have until recently been approached from disparate disciplinary perspectives. Scholars who specialize in tourism studies typically focus on issues such as economic policy, sustainability, and political implications; music scholars are more likely to concentrate on questions of identity, authenticity, neo-colonialism, and appropriation. Although the insights generated by these paths of scholarship have long been essential to study of the region, Sun, Sea, and Sound turns its attention to the dynamics and interrelationships between tourism and music throughout the region. Editors Timothy Rommen and Daniel T. Neely bring together a group of leading scholars from the fields of ethnomusicology, anthropology, mobility studies, and history to develop and explore a framework - termed music touristics - that considers music in relation to the wide range of tourist experiences that have developed in the region. Over the course of eleven chapters, the authors delve into an array of issues including the ways in which countries such as Jamaica and Cuba have used music to distinguish themselves within the international tourism industry, the tourism surrounding music festivals in St. Lucia and New Orleans, the intersections between music and sex tourism in Brazil, and spirituality tourism in Cuba. An indispensable resource for the study of music and tourism in global perspective, Sun, Sea, and Sound is essential reading for scholars and students across disciplines interested in the Caribbean region.