'Steve Brusatte, the author of The Rise and Fall of the Dinosaurs, brings mammals out from the shadow of their more showy predecessors in a beautifully written book that . . . makes the case for them as creatures who are just as engaging as dinosaurs.' - The Sunday Times, 'Best Books For Summer' 'In this terrific new book, Steve Brusatte . . . brings well-known extinct species, the sabre-toothed tigers and the woolly mammoths, thrillingly back to life' - The Times The passing of the age of the dinosaurs allowed mammals to become ascendant. But mammals have a much deeper history. They - or, more precisely, we - originated around the same time as the dinosaurs, over 200 million years ago; mammal roots lie even further back, some 325 million years. Over these immense stretches of geological time, mammals developed their trademark features: hair, keen senses of smell and hearing, big brains and sharp intelligence, fast growth and warm-blooded metabolism, a distinctive line-up of teeth (canines, incisors, premolars, molars), mammary glands that mothers use to nourish their babies with milk, qualities that have underlain their success story. Out of this long and rich evolutionary history came the mammals of today, including our own species and our closest cousins. But today's 6,000 mammal species - the egg-laying monotremes including the platypus, marsupials such as kangaroos and koalas that raise their tiny babies in pouches, and placentals like us, who give birth to well-developed young - are simply the few survivors of a once verdant family tree, which has been pruned both by time and mass extinctions. In The Rise and Reign of the Mammals, palaeontologist Steve Brusatte weaves together the history and evolution of our mammal forebears with stories of the scientists whose fieldwork and discoveries underlie our knowledge, both of iconic mammals like the mammoths and sabre-toothed tigers of which we have all heard, and of fascinating species that few of us are aware of. For what we see today is but a very limited range of the mammals that have existed; in this fascinating and ground-breaking book, Steve Brusatte tells their - and our - story.

1. Site Directed Mutagenesis to Probe for Active Site Components of Liver Mitochondrial Aldehyde Dehydrogenase.- 2. Substrate Binding Pocket Structure of Human Aldehyde Dehydrogenases: A Substrate Specificity Approach.- 3. Human Class 1 Aldehyde Dehydrogenase: Expression and Site-Directed Mutagenesis.- 4. Nitrate Esters as Inhibitors and Substrates of Aldehyde Dehydrogenase.- 5. Use of a Chromophoric Reporter Group to Probe the Active Site of Cytosolic Aldehyde Dehydrogenase.- 6. Studies of the Esterase Activity of Cytosolic Aldehyde Dehydrogenase Using Sterically Hindered and Cyclic Substrates.- 7. The Reduction of Propionic Anhydride by Aldehyde Dehydrogenase-Nadh Mixtures at pH 7.- 8. Cloning and Characterisation of the cDNA for Sheep Liver Cytosolic Aldehyde Dehydrogenase.- 9. Crystallization of Sheep Liver Cytosolic Aldehyde Dehydrogenase in a Form Suitable for High Resolution X-Ray Structural Analysis.- 10. Progress toward the Tertiary Structure of (Class 3) Aldehyde Dehydrogenase.- 11. UDP-Glucose Dehydrogenase: Structural Characteristics.- 12. Kinetic Studies on Class 3 Aldehyde Dehydrogenase from Bovine Cornea.- 13. Covalent Modification of Class 2 and Class 3 Aldehyde Dehydrogenase by 4-Hydroxynonenal.- 14. Constitutive and Overexpressed Human Cytosolic Class-3 Aldehyde Dehydrogenases in Normal and Neoplastic Cells/Secretions.- 15. Metabolism of Cyclophosphamide by Aldehyde Dehydrogenases.- 16. Tissue-Specific Expression and Preliminary Functional Analysis of the 5? Flanking Regions of the Human Mitochondrial Aldehyde Dehydrogenase (ALDH2) Gene.- 17. Transgenesis of the Aldehyde Dehydrogenase-2 (ALDH2) Locus in a Mouse Model and in Cultured Human Cells.- 18. Class 3 Aldehyde Dehydrogenase: A Northern Perspective in the Land Down Under.- 19. Studies on the Induction of Rat Class 3 Aldehyde Dehydrogenase.- 20. Mouse Class 3 Aldehyde Dehydrogenases.- 21. Cloning and Characterization of Genes Encoding Four Additional Human Aldehyde Dehydrogenase Isozymes.- 22. New Human Aldehyde Dehydrogenases.- 23. Retinoic Acid Synthesizing Enzymes in the Embryonic and Adult Vertebrate.- 24. Retinoic Acid Synthesis in the Developing Spinal Cord.- 25. Structure and Mechanism of Aldehyde Reductase.- 26. Expression of Human and Rat Carbonyl Reductase in E. coli: Comparison of the Recombinant Enzymes.- 27. Molecular Cloning and Sequencing of Mouse Hepatic 11ss-Hydroxysteroid Dehydrogenase/Carbonyl Reductase: A Member of the Short Chain Dehydrogenase Superfamily.- 28. Molecular Modelling Calculations on the Binding of D- and L-Xylose to Wild-Type Aldose Reductase and Its H11OQ and H11OA Mutants.- 29. Stopped-Flow Studies of Human Aldose Reductase Reveal which Enzyme Form Predominates during Steady-State Turnover in Either Reaction direction.- 30. Lysine Residues in the Coenzyme-Binding Region of Mouse Lung Carbonyl Reductase.- 31. Substrate Specificity and Kinetic Mechanism of Tetrahymena 20?-Hydroxysteroid Dehydrogenase.- 32. Purification and Characterization of Recombinant Human Placental and Rat Lens Aldose Reductases Expressed in Escherichia coli.- 33. Rat and Human Bile Acid Binders Are Members of the Monomeric Reductase Gene Family.- 34. The Alcohol Dehydrogenase System.- 35. Promoters of the Mammalian Class III Alcohol Dehydrogenase Genes.- 36. Class I and Class Iv Alcohol Dehydrogenase (Retinol Dehydrogenase) Gene Expression in Mouse Embryos.- 37. Molecular Evolution of Class I Alcohol Dehydrogenases in Primates: Models for Gene Evolution and Comparison of 3? Untranslated Regions of cDNAS.- 38. the Role of Leucine 116 in Determining Substrate Specificity in Human B1 Alcohol Dehydrogenase.- 39. Mutations of Human Class III Alcohol Dehydrogenase.- 40. Human and Rat Class IV Alcohol Dehydrogenases: Correlations of Primary Structures with Enzymatic Properties.- 41. Cloning and Expression of a Human Stomach Alcohol Dehydrogenase Isozyme.- 42. Purification and Properties of Murine Corneal Alcohol Dehydrogenase: Evidence for Class IV ADH P

The Reverend Sabine Baring-Gould (1834 - 1924) was an English hagiographer, antiquarian, novelist and eclectic scholar. His folkloric studies resulted in The Book of Werewolves, one of the most frequently cited studies of lycanthropy.

The Biology and Identification of the Coccidia (Apicomplexa) of Marsupials of the World contains the most up-to-date information on the former order marsupial that is now partitioned by mammalogists into seven separate orders that contain 20 families, 86 genera, and 318 species that live on land or in trees in Oceania and the Americas. Marsupials, like other vertebrate animals have many different kinds of parasites (e.g. viruses, protozoa, worms, arthropods, etc.), but there is no definitive text that covers any one of these groups found in all marsupials. Coccidiosis is a serious global problem in most domesticated animals, and under increasing circumstances of loss of habitat and crowding, may also affect some wild animal populations, thus, there is a real need for their identification and control.

With the substantial advances in the miniaturization of electronic components, wildlife biologists now routinely monitor the movements of free-ranging animals with radio-tracking devices. This book explicates the many analytical techniques and computer programs available to extract biological information from the radio tracking data.
Key Features:
* Presentation of software programs for solving specific problems
* Design of radio-tracking studies
* Mechanics of data collection
* Estimation of position by triangulation
* Graphic presentation of animal migration, dispersal, fidelity, and association
* Home range estimation, habitat utilization, and estimation of survival rates and population size

A review of our understanding of this area of the brain, showing how it fits into the general picture of those areas concerned with modulating mammalian behavior. The chapters, all written by leading figures in behavioral neuroscience, discuss the anatomy, neurochemistry, physiology, and behavioral relations in the septal area. Due to the great deal of current research shown in the related areas of hippocampus and the amygdala, this book will be of great interest to all those who research the hippocampus and the amygdala in addition to the septum itself.

From the Preface
The major change in the format of the fifth edition is the presentation of the book in two volumes, necessitated by the rapidly increasing knowledge of metabolism, interactions, and requirements of trace elements. The guiding principle was to present the minimum of results that would serve as a logical foundation for the description of the present state of knowledge.

This book addresses how skeletons can inform us about behavior by describing skeletal lesions in the Gombe chimpanzees, relating them to known life histories whenever possible, and analyzing demographic patterns in the sample. This is of particular interest to both primatologists and skeletal analysts who have benefited from published data on a smaller, earlier skeletal sample from Gombe. The Gombe skeletal collection is the largest collection of wild chimpanzees with known life histories in existence, and this work significantly expands the skeletal sample from this long-term research site (49 chimpanzees). The book explores topics of general interest to skeletal analysts such as demographic patterns, which injuries leave signs on the skeleton, and rates of healing, and discusses both qualitative and quantitative analysis of the patterning of lesions. The book presents the data in a narrative style similar to that employed in Dr. Goodall's seminal work The Chimpanzees of Gombe. Readers already familiar with the Gombe chimpanzees are likely to appreciate summaries of life events correlated to observable skeletal features. The book is especially relevant at this time to remind primate conservationists of the importance of the isolated chimpanzee population at Gombe National Park as well as the availability of the skeletons for study, both within the park itself as well as at the University of Minnesota.

The field of marine mammal science has made enormous strides in the last ten years of the 20th century, as well as attracting a large amount of interest, due no doubt to the public appeal of whales, dolphins, and seals, which are never out of media attention. The purpose of this book is to review key topics through chapters on the major disciplines from invited authorities around the world. Subjects covered include evolution and genetics, life histories, ecology, physiology, behaviour, medicine (diseases, parasitology), survey methodology, and all the main conservation issues (pollution, fisheries interactions, and sound disturbance). The book has an ecological and conservation emphasis since these are subject areas calling for the most attention in the modern world, but other areas such as evolution, physiology, and medicine are also given in-depth treatment. The book is written at the level of the undergraduate or above, although its style should appeal to anyone with a serious interest in marine mammal science.

Woolly monkeys are large, attractive and widespread primates found throughout many parts of the Amazon basin. It is only in the last twenty-five years or so that long-term studies of woollies in their forest habitat have been successful; they have not generally been successfully kept in captivity. But now, especially because of their size, these creatures are pressed on all sides by bush meat hunters and forest fragmentation. Their future is becoming critically precarious and the editors feel that it is time to showcase these animals with a full book.

The editors draw together a number of recent woolly monkey studies from three Amazonian countries, including five taxa of woolly monkeys, four of which have recently been reclassified without using new biological criteria as species rather than subspecies (Groves, 2001, 2005; Rylands & Mittermeier, 2009). This volume provides a diversity of studies by well-known researchers and advanced students on a wide range of subjects using newly generated data, including a criticism of the recent taxonomic changes. The varied information contained within "The Woolly Monkey: Behavior, Ecology, Systematics and Captive Research "will help readers understand these handsome animals and will, we hope, energize them to contribute to their conservation.

From the Preface
The major change in the format of the fifth edition is the presentation of the book in two volumes, necessitated by the rapidly increasing knowledge of metabolism, interactions, and requirements of trace elements ... The guiding principle was to present the minimum of results that would serve as a logical foundation for the description of the present state of knowledge.
Recent results of research were accommodated by devoting new chapters to the subjects "Methodology of Trace Element Research" and "Quality Assurance for Trace Element Analysis" and by expanding the discussion of lithium and aluminum in separate, new chapters. The first two subjects are of outstanding importance as determinants of future progress. The concern for the quality of analytical data motivated the authors of the individual chapters to review critically and, where necessary, revise analytical data presented in the previous editions. The rapid progress of trace analytical methodology since the mid-1970s has changed what had been accepted as normal for the concentrations of many trace elements in tissues and foods. The new data reflect the present state of the art in trace element analysis, but they may be subject to future revision.

This volume presents the latest research on herbivores, aquatic and terrestrial mammals and insects. The Second Edition, written almost entirely by new authors, effectively complements the initial work. It includes advances in molecular biology and microbiology, ecology, and evolutionary theory that have been achieved since the first edition was published in 1979. The book also incorporates relatively new methodologies in the area of molecular biology, like protein purification and gene cloning. Volume II, Ecological and Evolutionary Processes, also opens up entirely new subjects: The discussions of interactions have expanded to include phenomena at higher trophic levels, such as predation and microbial processing and other environmental influences.
Both this and Volume I, The Chemical Participants, will be of interest to chemists, biochemists, plant and insect ecologists, evolutionary biologists, physiologists, entomologists, and agroecologists interested in both crop and animal science.
Key Features
* Presents coevolution of herbivores and host plants
* Examines resource availability and its effects on secondary metabolism and herbivores
Studies physiology and biochemistry of adaptation to hosts
* Includes tri-trophic interactions involving predators and microbes

This book brings together scientific evidence and experience relevant to the practical conservation of bats. The authors worked with an international group of bat experts and conservationists to develop a global list of interventions that could benefit bats. For each intervention, the book summarises studies captured by the Conservation Evidence project, where that intervention has been tested and its effects on bats quantified. The result is a thorough guide to what is known, or not known, about the effectiveness of bat conservation actions throughout the world. Bat Conservation is the fifth in a series of Synopses that will cover different species groups and habitats, gradually building into a comprehensive summary of evidence on the effects of conservation interventions for all biodiversity throughout the world. By making evidence accessible in this way, we hope to enable a change in the practice of conservation, so it can become more evidence-based. We also aim to highlight where there are gaps in knowledge. Evidence from all around the world is included. If there appears to be a bias towards evidence from northern European or North American temperate environments, this reflects a current bias in the published research that is available to us. Conservation interventions are grouped primarily according to the relevant direct threats, as defined in the International Union for the Conservation of Nature (IUCN)'s Unified Classification of Direct Threats (www.iucnredlist.org/technical-documents/classification-schemes).

This volume presents the latest protocols for both laboratory and bioinformatics based analyses in the field of marine genomics. The chapters presented in the book cover a wide range of topics, including the sampling and genomics of bacterial communities, DNA extraction in marine organisms, high-throughput sequencing of whole mitochondrial genomes, phylogenomics, SNP discovery, SNP-arrays for species identification, digital PCR-based quantification methods, environment DNA for invasive species surveillance and monitoring, microarrays for the detection of waterborne pathogens, DNA barcoding of marine biodiversity, metabarcoding protocols for marine eukaryotes, analytical protocols for the visualization of eukaryotic diversity, and applications for genomic data to benthic indices for environmental monitoring. Written in the highly successful Methods in Molecular Biology series format, chapters include introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Marine Genomics: Methods and Protocols is a valuable resource for researchers, students, and policy makers in the field of marine biology.

"The Biology and Identification of the Coccidia (Apicomplexa) of Rabbits of the World" is a taxonomic summation of a damaging intestinal parasite found in rabbits and transmissible to other species, including humans. This book conceptually and historically summarizes the world's literature on the parasite and also provides a quick guide to isolation procedures, identification, strategies for management, and available chemotherapy. It is a vital source of knowledge about coccidia s real and potential transmission to humans, which can lead to dangerous health problems, like severe dehydration, vomiting, lethargy and even death.

Coccidiosis is an intestinal disease that affects several different animal species, including canines and humans, and is one of the most prevalent protozoal infections in North America. The causative agent is a protozoan that has the ability to multiply rapidly and cause major damage in the intestinal wall, rupturing the cells of the intestinal lining. The final stage, the oocyst, is extremely resistant to environmental stress and is difficult to completely remove from the environment. Oocysts are frequent contaminants of feed and water and when the sporulated oocysts are ingested by other animals, they start the life cycle over in the new host. With the demand for rabbits in scientific research and for rabbit meat for human consumption increasingly globally each year, rabbits are of epidemiologic significance for laboratory workers, university researchers, veterinarians, pet owners, and breeders.
Evaluates the scientific and scholarly merit of each of the publications written about coccidian from every rabbit species, providing a complete historical renditionA treatise for the identification of coccidia and their treatment as neededWritten in a style that can be understood by most educated lay persons and laboratory workersWritten by the first ranked author team among the world-class parasitologists who study coccidiaCombined in one single source, this book follows the gold standards in coccidian biology and identificationBrings all that information together in one volume and solves the problems faced by researchers, veterinarians, students and others in trying to find and navigate through this scattered literature"

Mammals range in body size from the gigantic blue whale to the tiny Etruscan shrew. Elephants and man may live for nearly one hundred years, while most shrews die before they are three months old. During the past decade, mammalogists and evolutionary biologists have begun to unravel the numerous factors that shape the enormous diversity of mammal life histories. In this volume, leading scientists provide a variety of perspectives on the newest theories in this active field of study. The principle uniting all studies of life history evolution is adaptation by natural selection. The first chapters in the book discuss this topic, offering evolutionary interpretations of geographic variation in mammal life histories, explaining how natural selection operates in fluctuating environments, introducing evolutionary predictions of demographic mathematics, and integrating life histories with behavioral ecology. The next chapters offer functional interpretations of the importance of body size in the life history. Next, several essays explain how developments in quantitative genetics have enabled us to distinguish between genetic and environmental components of variation within and between species. With this as a basis, the chapters that follow draw from principles of natural selection, allometry, and genetics to interpret differences among species of mammals. The book concludes with speculations on various areas where research seems most urgent for the development of a comprehensive understanding of mammal life history evolution. According to the authors, the field is rich with questions, and opportunities abound for both theoretical and empirical research.

Why do females in male-philopatric species seem to show larger variation in their life history strategies than males in female-philopatric species? Why did females in human societies come to show enormous variation in the patterns of marriage, residence and mating activities? To tackle these important questions, this book presents the latest knowledge about the dispersing females in male-philopatric non-human primates and in human societies. The non-human primates that are covered include muriquis, spider monkeys, woolly monkeys, gorillas, chimpanzees, bonobos and some species of colobine monkeys. In these non-human primate species females typically leave their natal group before sexual maturation and start reproduction in other groups into which they immigrate. However, there is a large variation as some females may breed in their natal group with some risks of inbreeding with their male relatives and some females may associate with males of multiple groups at the same time after leaving their natal group. Such variation seems to provide better strategies for reproduction depending on local circumstances. Although knowledge about female dispersal patterns and life history is indispensable for understanding the dynamic structure of primate societies, it is still not known how females behave after leaving their natal groups, how many groups they visit before finally settling down and which kinds of groups they choose to immigrate into, due to the large variation and flexibility and the difficulty of tracking females after natal dispersal. To encourage further progress in this important field, this volume provides new insights on evolution of female dispersal by describing factors influencing variations in the dispersal pattern across primates and a hypothesis for the formation of human families from the perspectives of female life history. This book is recommended reading for researchers and students in primatology, anthropology, animal behavior and evolution and for anyone interested in primate societies and human evolution.

Mammary Development: Growth and Growth Factors: The Environment of the Mammary Secretory Cell (C.H. Knight). Role of Bovine Placental Lactogen in Intercellular Signalling during Mammary Growth and Lactation (R.J. Collier et al.). Expression of Hox Genes in Normal and Neoplastic Mouse Mammary Gland (Y. Friedmann, C.W. Daniel). Apoptosis in Mammary Gland Involution: Isolation and Characterization of Apoptosisspecific Genes (W. Bielke et al.). Mammary Development: Differentiation and Gene Expression: Extracellular Matrix Dependent Gene Regulation in Mammary Epithelial Cells (C. Schmidhauser et al.). Regulation of Milk Secretion and Composition by Growth Hormone and Prolactin (D.J. Flint). Basement Membrane in the Control of Mammary Gland Function (C.H. Streuli). Heterogeneous Expression and Synthesis of Human Serum Albumin in the Mammary Gland of Transgenic Mice (I. Barash et al). Milk Secretion: Autocrine Control of Milk Secretion: Development of the Concept (M. Peaker). Endocrine and Autocrine Strategies for the Control of Lactation in Women and Sows (P.E. Hartmann et al.). Autocrine Control of Milk Secretion: From Concept to Application (C.J. Wilde et al.). A Role for Mediumchain Fatty Acids in the Regulation of Lipid Synthesis in Milk Stasis? (D.H. Williamson et al.). 41 additional articles. Appendix. Index.

The list of challenges facing nonhuman primates in the 21st century is a long one. The expansion of palm oil plantations to feed a growing consumer class is eating away at ape and monkey habitats in Southeast Asia and Central Africa. Lemurs are hunted for food in the poorest parts of Madagascar while monkeys are used as medicine in Brazil. Traditional cultural beliefs are maintaining demand for animal body parts in West African markets while viral YouTube videos of "cute" and "cuddly" lorises have increased their market value as pets and endangered their populations. These and other issues are addressed in this book by leading researchers in the field of ethnoprimatology, the study of human/nonhuman primate interactions that combines traditional primatological methodologies with cultural anthropology in an effort to better understand the nuances of our economic, ritualistic, and ecologic relationships.

This is a careful study of obstetrical mechanics in monkeys, apes, and extinct hominids in order to understand the present crisis in human reproduction. Current obstetrical problems have an anthropological origin. Cesarean section, almost unknown at the beginning of the century, is now considered necessary in more than 25% of deliveries. By studying the evolution of anatomical structures and the mode of delivery among other primates, strong reasons are apparent for the present crisis in human labor and delivery. This unique study points the way to further evolution of the human birth process.

Spider monkeys are one of the most widespread New World primate genera, ranging from southern Mexico to Bolivia. Although they are common in zoos, spider monkeys are traditionally very difficult to study in the wild, because they are fast moving, live high in the canopy and are almost always found in small subgroups that vary in size and composition throughout the day. The past decade has seen an expansion in research being carried out on this genus and this book is an assimilation of both published and previously unpublished research. It is a comprehensive source of information for academic researchers and graduate students interested in primatology, evolutionary anthropology and behavioral ecology and covers topics such as taxonomy, diet, sexuality and reproduction, and conservation.

Illustrated throughout with 200 outstanding colour photographs, Endangered Animals presents an in-depth look at around 100 species of animal from around the world, all of which are currently endangered or threatened according to the annual list drawn up by the World Conservation Union (IUCN). The selection spans a broad spectrum of wildlife, from large, charismatic mammals such as the Bengal tiger to lesser-known species such as New Zealand's kakapo, the world's only flightless parrot, which was once presumed to be extinct. Each continent is covered, with examples carefully drawn from every habitat - from the mysterious aye-aye of Madagascar's shrinking rainforest, to the shy spectacled bear of the high Andes. Arranged geographically, each photographic entry is supported by a fascinating caption, which explains the animal's current plight and whether it is critically endangered or classified as vulnerable. From the Ethiopian wolf to the Bengal tiger to monk seal and dugong, Endangered Animals is a fascinating introduction to some of the most threatened species on the planet.

The immune systems of human and non-human primates have diverged over time, such that some species differ considerably in their susceptibility, symptoms, and survival of particular infectious diseases. Variation in primate immunity is such that major human pathogens - such as immunodeficiency viruses, herpesviruses and malaria-inducing species of"Plasmodium"- elicit striking differences in immune response between closely related species and within primate populations. These differences in immunity are the outcome of complex evolutionary processes that include interactions between the host, its pathogens and symbiont/commensal organisms. The success of some pathogens in establishing persistent infections inhumans and other primateshas been determined not just by the molecular evolution of the pathogen and its interactions with the host, but also by the evolution of primate behavior and ecology, microflora, immune factors and the evolution of other biological systems.

To explore how interactions between primates and their pathogenshave shaped their mutual molecular evolution, "Primates, Pathogens and Evolution"brings together research that explorescomparativeprimate immune function, the emergence of major and neglected primatediseases, primate-microorganism molecular interactions, and related topics. Thisbookwill be of interest to anyone curious as to why infectious diseases manifest differently in humans and their closest relatives. It will be of particular interest to scholars specializing in humanand non-human primate evolution, epidemiology and immunology, and disease ecology."Primates, Pathogens and Evolution"offers anoverview and discussion of current findings on differences in the molecular mechanics of primate immune response, as well as on pathogen-mediated primate evolution and human and non-human primate health."