This fourth edition of Fundamentals of Research Methodology for Healthcare Professionals has been updated to incorporate the latest trends in research methodology and evidence-based practice. It details the steps involved in planning and undertaking a research project, from identifying and formulating the problem through to reporting findings. It underscores the importance of having a clear understanding of research methodology and terminology for doing the following: reading research reports with critical insight, implementing evidence-based practice, and expanding research. This edition is certain to stimulate awareness of the myriad researchable and research-requiring questions encountered daily in healthcare practice. Key features include: - clearly defined learning objectives to indicate the focus of each chapter - practical examples of research projects or steps in the research process - chapter summaries to reinforce learning - exercises to put the theory into practice - a practical, hands-on introduction to research methodology.

Translating microRNA to the Clinic reviews the possibilities of current methodological tools and experimental approaches used by leading translational researchers. The book features the uses of micro ribonucleic acid as deployed in cancer targeting in biomarkers, diabetes, cardiovascular disease, and neurodegeneration, among many others. Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field, promoting a cross-disciplinary communication between the sub-specialities of medicine, but in common with other books on the topic. In addition, the book emphasizes recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole.

This text is a review of molecular immunohematology (MI). It draws from analyses and case studies around the world and details many techniques used in many labs. It is aimed at anyone interested in how MI is changing blood bank and transfusion medicine.

Genetically-engineered mouse models for cancer research have become invaluable tools for studying cancer biology and evaluating novel therapeutic approaches. This volume focuses on state-of-the-art methods for generating, analyzing and validating such models for studying aspects of human cancer biology. Additionally, these models are emerging as important pre-clinical systems in which to test cancer prevention and therapeutic strategies in order to select compounds for testing in clinical trials.

Breast cancer remains a disease of considerable public health importance worldwide, with over 800,000 new cases diagnosed globally each year. Considerable energy is currently being spent by researchers to further our understanding of this complex disease, however, keeping up with all of the new data is a real challenge given the sheer volume of information that becomes available on a daily basis. The purpose of this book would be to provide a comprehensive review of breast cancer epidemiology, covering the topics of disease burden, etiology, risk factors, prevention, early detection/screening, treatment, and outcomes. The book would be a single comprehensive source of the most recent information on breast cancer epidemiology, and it would serve as a valuable resource for breast cancer researchers across disciplines regardless of what stage of their career they are in. To the knowledge of the editor, no such resource is currently available.

Volume 69 in the internationally acclaimed Advances in Clinical Chemistry contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists. The serial provides the latest and most up-to-date technologies related to the field of Clinical Chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

Point of care testing (POCT) is a new concept in laboratory medicine that is widely used at present. It is the new advent that helps ease medical care in the present day. The knowledge on the POCT medicine is very important and necessary for the general practitioner. In this specific book, the author summarizes, presents and discusses on the concept of POCT, its importance and examples of important POCT tools.

Volume63 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists.The serialprovides the latest and most up-to-date technologies related to the field of Clinical Chemistry andis the benchmark for novel analytical approaches in the clinical laboratory.
Expertise of international contributorsLatest cutting-edge technologiesComprehensive in scope"

In a perfect world, after their clinical rotation, CLSs and MLTs will be working in all four areas of study of medical technology (Microbiology, Chemistry, Hematology and Immunohematology), retain all that they know and live and work happily ever after. But as we all know that is far from the case, more frequently than not, a CLS or MLT will be stuck in one or two specialized area of study. Mycology is a unique sub-subspecialty of Microbiology that both the macroscopic and microscopic part of it require years of experience for a CLS to feel a high level of confidence. CLSs who had been away from the Mycology department for a period of time or never had a chance to work in the Mycology department will need a good refresher course before venturing into this department. This manual does not claim to be able to boost someone's confidence overnight or claim to have all the answers, but instead this manual serves as a guide to re-discovering what one previously knew. My hope is that this manual will serve its purpose and be a source of confidence to those who are brave enough to venture out in the mycology department as a newbee or someone who had been away from it for a period of time.

Volume62 in the internationally acclaimed "Advances in Clinical Chemistry" contains chapters authored by world renowned clinical laboratory scientists, physicians and research scientists.The serialprovides the latest and most up-to-date technologies related to the field of Clinical Chemistry andis the benchmark for novel analytical approaches in the clinical laboratory.
Expertise of international contributorsLatest cutting-edge technologiesComprehensive in scope"

"Laboratory Animals: Regulations and Recommendations for Global Collaborative Research" is the only publication to offer a compilation of standards across the world in the care, welfare and use of animals in research. Timely in the new legislation in numerous regions of the world, this book provides the information in easily accessible, readable language.

For professionals across laboratory animal science and biomedical research, "Laboratory Animals: Regulations and Recommendations for Global Collaborative Research" provides a broad picture of the regulations required in other areas of the world and is essential to appropriately manage animal care and use programs.
Offers a worldwide view and global compilation of regulations, guidelines and recommendations for laboratory animal researchSaves valuable time researching different regional legislation and regulationsProvides insight into factors that play roles in the regulatory framework for countries and geographic regionsWritten in "layman s" terms to easily understand legislation and regulations"

A Guide to Technical Consulting for the Clinical Laboratory offers consulting guidance to provide regulatory instruction to qualified individuals, especially medical technologists who want to pursue a career as a technical consultant for a clinical laboratory. Cathy Manske has more than 40 years' experience working in the field of medical technology as a laboratorian, researcher, and consultant. A Wisconsin transplant to Arizona, she was educated at the University of Wisconsin-Milwaukee, receiving a B.S. in medical technology. Her early work experience was as a generalist in hospitals, and then specializing in microbiology and virology, ultimately becoming a technical consultant to physicians whose offices implemented in-house clinical laboratories. In 2003, she created and incorporated Clinical Laboratory Consultants, Ltd. Since then, she has helped set up more than 60 physicians' office laboratories of varying specialties including pediatric, cardiac, internal, rheumatoid, OBGYN, oncology, endocrinology, urology, and family practice. She also set up six reference laboratories. In addition to starting up clinical labs, she consults with over 20 laboratories in an ongoing technical consultant capacity, and occasionally serving as laboratory director. She successfully guides her clients to full CLIA compliance, while ensuring both accurate testing analysis and profitability. Beyond her thorough knowledge of standard lab practices and prevailing state and federal regulations, the author's strength lies in communicating effectively with CLIA inspectors, doctors, administrators, and laboratory staff. Cathy L. Manske hopes her book will encourage more medical technologists and qualified professionals to pursue the field of laboratory technical consulting. This is her first book. Publisher's website: http: //sbprabooks.com/CathyLManske

"The Path from Biomarker Discovery to Regulatory Qualification "is a unique guide that focuses on biomarker qualification, its history and current regulatory settings in both the US and abroad. This multi-contributed book provides a detailed look at the next step to developing biomarkers for clinical use and covers overall concepts, challenges, strategies and solutions based on the experiences of regulatory authorities and scientists. Members of the regulatory, pharmaceutical and biomarker development communities will benefit the most from using this book-it is a complete and practical guide to biomarker qualification, providing valuable insight to an ever-evolving and important area of regulatory science.

For complimentary access to chapter 13, "'""Classic' Biomarkers of Liver Injury, " by John R. Senior, Associate Director for Science, Food and Drug Administration, Silver Spring, Maryland, USA, please visit the following site: http: //tinyurl.com/ClassicBiomarkers
Contains a collection of experiences of different groups taking different types of biomarkers to different levels of qualification and provides insightful case studies of an important area of regulatory science

Focuses on practical advice, concepts, strategies and overall outcomes to support those working toward biomarker qualification for clinical use

Offers a valuable resource for members of the regulatory, pharmaceutical and biomarker development communities. "

With the first IVF treatments, many skeptics rejected the process due to the possibility of something going wrong. But with time, this new way of conceiving became accepted throughout the world. But there is always a danger that somebody might come up with an unethical and dangerous idea to influence the process of fetal development in order to be able to offer his or her services to the people who would be prepared to pay enormous sums and in this way endanger the lives of the innocent newborn.

With time and effort, some of the ideas, impossible today, might be achievable in the future and it could go beyond our present understanding but we should be on guard that it does not go beyond our control.