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Books > Medicine > Clinical & internal medicine > Musculoskeletal medicine

Understanding the Head & Neck Paper Poster (Poster): Scientific Publishing Understanding the Head & Neck Paper Poster (Poster)
Scientific Publishing
R241 Discovery Miles 2 410 Ships in 12 - 17 working days
Living the Best Life with Fibromyalgia (Paperback): Alisha Nurse M a Living the Best Life with Fibromyalgia (Paperback)
Alisha Nurse M a
R186 Discovery Miles 1 860 Ships in 10 - 15 working days
Bursitis of Major Joints (Hardcover): Alessandro Aprato Bursitis of Major Joints (Hardcover)
Alessandro Aprato
R3,959 Discovery Miles 39 590 Ships in 12 - 17 working days

Inflammation or irritation of the bursa in the major joints is most often caused by repetitive, minor impact on the area, or from a sudden, more serious injury. Age also plays a role. Overuse or injury to the joint at work or play can also increase a person's risk of bursitis. Incorrect posture at work or home and poor stretching or conditioning before exercise can also lead to bursitis. Anatomic deformities may also add stress on a bursa sac, causing bursitis. Stress or inflammation from other conditions, such as rheumatoid arthritis, gout, psoriatic arthritis, thyroid disorders, or unusual medication reactions may also increase a person's risk. In addition, an infection can occasionally lead to inflammation of a bursa. The most common symptoms of bursitis are pain, stiffness and swelling. The pain may build up gradually or be sudden and severe, especially if calcium deposits are present. Bursitis diagnosis may occur after a clinical examination and it is usually confirmed by imaging such as with an ultrasound or MRI. X-ray images can't positively establish the diagnosis of bursitis, but they can help to exclude other causes of your discomfort. Bursitis can be treated in a number of ways, including rest, nonsteroidal anti-inflammatory drugs, corticosteroids, injections of local anaesthetic or corticosteroids, physical therapy and, in rare cases, surgery. The authors also discuss the treatment options for bursitis in this book.

Fundamental Role of Muscle Contractures in Musculoskeletal Diseases - An Introduction to Brachymyotherapy (Hardcover): Jan Polak Fundamental Role of Muscle Contractures in Musculoskeletal Diseases - An Introduction to Brachymyotherapy (Hardcover)
Jan Polak
R5,029 Discovery Miles 50 290 Ships in 12 - 17 working days

In the explanation of musculoskeletal disorders, the skeleton is usually put forward, and the muscles tend to be forgotten. This seems to be a mistake, and leads to some common misunderstandings, like osteoarthritis being the cause of joint pain, rheumatoid arthritis being an auto-immune disease, disc herniation as the cause of low back pain, meniscal injury as the cause of knee pain, etc. This in turn will lead to inappropriate treatments like painkillers - which sometimes kill the patient, and anyway never treat the root of the pain - or to avoidable surgery. Misunderstanding the role of muscle contractures in other ailments like scoliosis or migraine has not allowed so far a disease-modifying treatment. All the above-mentioned disorders can however be cured, in most cases, by manually treating the causal muscle contractures, which is rather simple. This book explains the origin, the mechanism and the consequences of muscle contractures, as well as the pathomechanisms of joint pains, scoliosis, migraine, and several other diseases, and the principles of their treatment. We will present several research studies showing the efficiency of a simple manual treatment of the contractured muscles that are the prime movers of these diseases.

Pelvic Pain - A Musculoskeletal Approach for Treatment (Paperback): Peter Dornan Pelvic Pain - A Musculoskeletal Approach for Treatment (Paperback)
Peter Dornan
R1,196 Discovery Miles 11 960 Ships in 10 - 15 working days

Over the last ten years, and after treating nearly 6,000 patients, physiotherapist Peter Dornan has found that many conditions that may have -resisted -traditional medical intervention such as:pain in the scrotum, labia, perineum or anorectal region, penis;dysuria (painful urination);urinary and faecal urge incontinence;pain during or after ejaculation;sexual and erectile dysfunction;are often associated with pelvic girdle dysfunction -involving the -sacroiliac joint.In this book he outlines methods and -evidence-based treatment for the dysfunction and management of symptoms, using helpful -illustrations and photos to highlight the concepts and techniques that are covered.Pelvic Pain: a Musculosketal Approach for Treatment will prove useful to patients as well as health professionals who have an -interest in pelvic pain, particularly musculoskeletal therapists.

Body Mechanics in Health and Disease (Paperback): Joel E Goldthwait, Lloyd T Brown, Loring T Swaim Body Mechanics in Health and Disease (Paperback)
Joel E Goldthwait, Lloyd T Brown, Loring T Swaim
R750 Discovery Miles 7 500 Ships in 10 - 15 working days
Musculoskeletal Diseases - Types, Causes & Treatments (Paperback): Greg Reed Musculoskeletal Diseases - Types, Causes & Treatments (Paperback)
Greg Reed
R2,887 Discovery Miles 28 870 Ships in 12 - 17 working days

Musculoskeletal Disorders (MSD) are one of the leading classes of health effects and can be caused by various factors, work related and non-work related. MSD refers to health related problems of the locomotor apparatus, i.e. health problems of the skeleton, ligament, muscles, tendons, joints, nerves and cartilage. Rates of musculoskeletal disorders vary by population, their age groups, genders, socioeconomic aspects and other factors. These factors can affect our understanding of the prevalence, incidence, and costs of musculoskeletal disorders aside from the variability of actual prevalence or incidence rates due to etiologic issues or costs due to illness or injury severity or treatment response and recovery. This book provides an analysis of costs of musculoskeletal disorders of employed individuals. It also discusses the application of differential scanning calorimetry for the diagnosis of musculoskeletal disorders, and the effects of stretching and sensory motor training for older adults with musculoskeletal disorders.

Manual der OSTEOSYNTHESE - AO-Technik (German, Paperback, 3. Aufl. 1992. Softcover reprint of the original 3rd ed. 1992): S.M.... Manual der OSTEOSYNTHESE - AO-Technik (German, Paperback, 3. Aufl. 1992. Softcover reprint of the original 3rd ed. 1992)
S.M. Perren; Maurice E. Muller; Edited by (board members) Martin Allgoewer; Martin Allgoewer, Robert Schneider, …
R2,221 Discovery Miles 22 210 Ships in 12 - 17 working days

Dank verbessertem Instrumentarium und besserem Verstandnis fur die Prinzipien (Behrens und Searls 1986) zum sicheren und wirkungsvollen Gebrauch, wurde der Fixateur externe zu einem unersetzbaren Werkzeug eines jeden erfahrenen Traumatologen. Als wichtigste Indikationen fur den Fixateur externe gelten die 2 Degrees und 3 Degrees offenen Frakturen, infizierte Pseudarthrosen sowie Korrektureingriffe bei Achsenabweichungen und Langendifferenz. Der Fixateur externe wird weiter eingesetzt zur raschen, initialenRuhigstellungvon Weich- teilverletzungen und Frakturen bei Schwerstverletzten, zur Ruhigstellung geschlossener Frakturen mit schwerem Weichteiltrauma (Quetschung des Weichteilmantels, Verbrennun- gen, dermatologische Erkrankungen), bei ausgedehnten Schaft-und periartikularen Bru- chen, zur vorubergehenden gelenkuberbruckenden Ruhigstellung schwerer Weichteil-und Bandverletzungen, bei bestimmten Beckenringverletzungen und ausgewahlten Kinderfrak- turen sowie fur Arthrodesen und Osteotomien. Der Fixateur externe besitzt die einzigartige Moeglichkeit, Knochen-und Weichteile weit ausserhalb der Operations-oder Verletzungszone zu stabilisieren. Falls korrekt angewendet, gewahrt er ungehinderten Zugang zu den entscheidenden Skelett-und Weichteilstrukturen, so dass sowohl Initialversorgung als auch sekundare Wiederherstellung des Knochens und Weichteilmantels ermoeglicht wird. Durch die Verwendung des Fixateur externe bleibt das zusatzliche Gewebetrauma zur primaren Skelett- und Weichteilverletzung sehr gering. Auch das Infektrisiko ist geringer als das bei einer "inneren" Osteosynthese.

Schulterendoprothetik (German, Paperback, Softcover Reprint of the Original 1st 1987 ed.): Reinhard Koelbel, Bodo Helbig,... Schulterendoprothetik (German, Paperback, Softcover Reprint of the Original 1st 1987 ed.)
Reinhard Koelbel, Bodo Helbig, Walter Blauth
R1,960 Discovery Miles 19 600 Ships in 12 - 17 working days

Unter den zahlreichen Kunstgelenken, die in den letzten 21ahrzehnten entwickelt und implantiert worden sind, spielen Schultergelenkendoprothesen noch eine ver- gleichsweise geringe Rolle. Dies hangt v.a. mit den anatomischen, biomechani- schen und funktionellen Besonderheiten des Schultergelenks zusammen. Nur an wenigen Kliniken liegen im deutschen Sprachraum bisher gr613ere Erfah- rungen mit der Schuiterendoprothetik vor. Sie beziehen sich hauptsachlich auf Pati- enten mit Gelenkzerst6rungen nach schweren Unfallfolgen, Knochentumoren, rheumatoider Arthritis oder degenerativen Schultererkrankungen. So wird viel- leicht verstandlich, warum das Thema "ktinstlicher Schultergelenkersatz" auf unse- ren Kongressen und Symposien bisher kaum zur Sprache kam. Es lag deshalb nahe, die 35. lahrestagung Nordwestdeutscher Orthopaden im lu- ni 1985 in Kiel zum Anlal3 zu nehmen, den gegenwartigen Stand der Schulterendo- prothetik einmal ausfUhrlich darzustellen und zu diskutieren. Dazu wurden viele der fUhrenden Spezialisten aus dem europaischen Ausland, aus Ubersee und dem deutschen Sprachraum eingeladen, urn tiber ihre Erfahrungen zu berichten. Die Veranstaltung erstreckte sich tiber 2Y2 Tage, die Teilnehmerzahl war auf etwa 100 begrenzt. Eine hervorragende Simultantibersetzung durch Frau Dr. med. A. Beisel, Heidel- berg (Leitung), Mrs. K. Band und Herrn Dip\.-Volksw. E. Feldberg, alle Konferenz- dolmetscher A. I. I. C, sorgte fUr einen lebendigen Gedankenaustausch aller Teil- nehmer, der in keiner Weise zeitlich eingeschrankt war. In der vorliegenden Monographie sind samtliche Beitrage und die wesentlichen Diskussionsbemerkungen zusammengefal3t.

Osteoarthritis: The Facts (Paperback, 2nd Revised edition): Daniel Prieto-Alhambra, Nigel Arden, David J Hunter Osteoarthritis: The Facts (Paperback, 2nd Revised edition)
Daniel Prieto-Alhambra, Nigel Arden, David J Hunter
R613 Discovery Miles 6 130 Ships in 12 - 17 working days

Osteoarthritis: The Facts helps patients and their carers better understand the condition, empowering patients with the knowledge and skills to actively take charge of their own health by knowing as much as they can about osteoarthritis, and finding out how this can be best managed. Part 1 details what osteoarthritis is, what causes it, who it affects, what the main symptoms are, how it is diagnosed, and what the long-term outcome is. Part 2 explains the potential aspects of management that can be used for osteoarthritis, including self-management strategies, exercise, diet, medications, surgical treatments, and alternative therapies. Osteoarthritis: The Facts also includes a useful resources section, including information on support groups and websites, providing the reader with an opportunity to educate and empower themselves with tools that will help reduce their suffering.

Psoriatic Arthritis (Paperback, New): Dafna Gladman, Cheryl F. Rosen, Vinod Chandran Psoriatic Arthritis (Paperback, New)
Dafna Gladman, Cheryl F. Rosen, Vinod Chandran
R1,333 Discovery Miles 13 330 Ships in 10 - 15 working days

Over the past 30 years, there has been increasing recognition of psoriatic arthritis as a distinct clinical entity. Psoriatic arthritis occurs mostly in patients with psoriasis and may affect up to 1% of the general population. It has many similarities to other forms of spondyloarthritis, and must be differentiated from related conditions. Given that most patients with psoriatic arthritis have skin and musculoskeletal diseases that significantly affect their quality of life and function, patients are ideally managed in a multidisciplinary clinic with rheumatologists, dermatologists and a nurse specialist, physical therapist and occupational therapist. Psoriatic Arthritis covers the epidemiology and diagnostic and classification criteria, describing the clinical features of the disease, including skin and nail involvement, articular, and other extra-articular manifestations. Laboratory features and imaging characteristics are covered in detail, along with co-morbidities and their impact. A comprehensive review of skin disease therapy is also provided, along with the various treatment options for joint disease, including traditional disease modifying therapy and newer biologic agents . This comprehensive yet concise and practical volume is the perfect guide to psoriatic arthritis for the busy practitioner, and will be of interest to trainees and specialists in rheumatology and dermatology.

Gelenkpathologie - Historische Grundlagen, Ursachen und Entwicklungen von Gelenkleiden und ihre Pathomorphologie (German,... Gelenkpathologie - Historische Grundlagen, Ursachen und Entwicklungen von Gelenkleiden und ihre Pathomorphologie (German, Paperback, Softcover reprint of the original 1st ed. 2000)
Winfried Mohr; Assisted by R. Endres-Klein
R2,941 Discovery Miles 29 410 Ships in 12 - 17 working days

Dieser umfassende Uberblick vermittelt Ihnen klinikbezogen das aktuelle Wissen zur allgemeinen und speziellen Pathologie der Gelenkerkrankungen und des Bindegewebes.
Didaktisch klar, mit umfangreichem Abbildungsmaterial
- Fundierte Darstellung der Pathogenese und Morphologie
- Detaillierte Beschreibung der einzelnen Krankheiten
- Mikroskopischer, makroskopischer und Rontgenbefund ubersichtlich in synoptischen Tableaus
Ein Handbuch und Nachschlagewerk, das Ihnen praktische Entscheidungshilfen fur die Befundinterpretation und Therapie liefert."

Musculoskeletal Imaging Cases (Paperback): Mark W. Anderson, Stacy E. Smith Musculoskeletal Imaging Cases (Paperback)
Mark W. Anderson, Stacy E. Smith
R3,528 Discovery Miles 35 280 Ships in 10 - 15 working days

Through 145 clinically-relevant cases, Musculoskeletal Imaging Cases covers the full spectrum of imaging for this field. Part of the Cases in Radiology series, this book follows the easy-to-learn case format of question and answer, complete with concise summaries and a generous amount of top-quality images. Pathologies addressed in the cases include: arthritis, bone and soft tissue tumors and tumor-like conditions, infection, trauma, internal derangement of joints, metabolic and hematologic disorders affecting the MSK system, bone marrow, infection, and pediatric problems. Within their sections, cases appear in a random order for the beneficial self-assessment experience of the reading cases as unknowns. Musculoskeletal Imaging Cases is ideal for the resident preparing for the boards, or the radiologist in need of a quick review.

100 Cases in Orthopaedics and Rheumatology (Paperback, New): Parminder Singh, Catherine Swales 100 Cases in Orthopaedics and Rheumatology (Paperback, New)
Parminder Singh, Catherine Swales
R1,110 Discovery Miles 11 100 Ships in 9 - 15 working days

A 24-year-old woman attends rheumatology outpatients with an eight-week history of painful hands. On examination she is tearful and thin. You are the medic on duty... 100 Cases in Orthopaedics and Rheumatology presents 100 scenarios commonly seen by medical students and junior doctors in orthopaedic and rheumatology clinics, or in the emergency department. A succinct summary of the patient's history, examination and initial investigations, with clinical and/or imaging photographs, is followed by questions on the diagnosis and management of each case. The answer includes a detailed discussion on each topic, with further illustration where appropriate, providing an essential revision aid as well as a practical guide for students and junior doctors. Making clinical decisions and choosing the best course of action is one of the most challenging and difficult parts of training to become a doctor. These cases will teach students and junior doctors to recognize important symptoms and signs and, where appropriate, their relationship to other medical conditions, and to develop their diagnostic and management skills.

Mesenchymal Stem Cells and Skeletal Regeneration (Paperback, New): Peter Giannoudis, Elena Jones, Xuebin Yang, Dennis McGonagle Mesenchymal Stem Cells and Skeletal Regeneration (Paperback, New)
Peter Giannoudis, Elena Jones, Xuebin Yang, Dennis McGonagle
R964 Discovery Miles 9 640 Ships in 10 - 15 working days

This book covers our current understanding of the role of mesenchymal stem cells (MSCs) and other mesenchymal progenitors in skeletal regeneration, encompassing bone, cartilage and whole joint regeneration. The expansion reflects developments in the field to include data on the use of MSCs in drug development, growth factors, scaffolds and biomechanical manipulations for skeletal trauma and diseases, including osteoporosis and arthritis.

Written for an audience of clinicians and young researchers who are exposed to MSCs in their work, this work summarizes recent findings pertaining to the definition and characterization of MSCs in skeletal tissues and discusses the mechanisms of their actions in regeneration of bone in vivo. The authors describe recent findings pertaining to the efficacy of MSC therapies in animal models and in human clinical trials and bring together literature showing that the ways MSCs are extracted, expanded and implanted can considerably affect bone formation outcomes. Finally, it presents the latest knowledge on the nature of native MSCs in skeletal tissues, which provide a platform for novel in situ tissue regeneration approaches for systemic bone disease such as osteoporosis.
Focuses specifically on the use of stem cells in skeletal tissue generation for a broad audience of stem cell, cancer, and bone biologists, orthopedists, oncologists, and regenerative medicine specialistsProvides a short historical detour and foundational information on founding concepts, discoveries and personalities in MSC researchAssists a new generation of scientists and clinicians in digesting the multitude of journal articles on the topic by providing easily-absorbed and condensed foundational context"

Osteoblasts - Morphology, Functions & Clinical Implications (Hardcover): Hugo Scheurer Osteoblasts - Morphology, Functions & Clinical Implications (Hardcover)
Hugo Scheurer
R4,312 Discovery Miles 43 120 Ships in 12 - 17 working days

Osteoblasts are highly specialised mesenchymal cells that are mainly responsible for the formation and maintenance of the skeletal architecture. They produce extracellular matrix proteins and are regulators of matrix mineralisation during bone formation and remodelling. In this book, the authors discuss the morphology, functions and clinical implications of osteoblasts. Topics include osteoblasts under mechanical strain; mesenchymal stem cells (MSC) into osteoblasts for bone tissue engineering; osteoblast function and their role in skeletal bone diseases; bone morphogenetic proteins (BMP) and osteoblastogenesis inhibitors; the effect of molecular and biochemical differentiation agents on bone formation; and the evaluation of characteristics of osteoblasts and factors related to osteoblastic differentiation and mineralisation.

Scoliosis - Causes, Symptoms & Treatment (Paperback, New): Absolon Bessette, Coralie M Rousseau Scoliosis - Causes, Symptoms & Treatment (Paperback, New)
Absolon Bessette, Coralie M Rousseau
R1,775 Discovery Miles 17 750 Ships in 12 - 17 working days

Scoliosis is a lateral spinal deformity often coupled with vertebral rotation with most of the cases presenting as idiopathic. In this book, the authors present topical research in the study of the causes, symptoms and treatment of scoliosis. Topics discussed include the history and classification of scoliosis; the connection between idiopathic scoliosis, orthodontics and occlusion and their therapeutic implications; the trunk posture of the elderly population in Southern Brazil using the Shadow Moire Technique; new physical therapy interventions for scoliosis; effects of load carriage on children with scoliosis; and the relationship of the pineal gland, melatonin and scoliosis.

Electromyography - New Developments, Procedures & Applications (Hardcover): Hiroki Takada Electromyography - New Developments, Procedures & Applications (Hardcover)
Hiroki Takada
R4,062 Discovery Miles 40 620 Ships in 12 - 17 working days

Italian physician L Galvani demonstrated the relationship between electricity and muscle contraction that occurs in the electric fluid carried to the muscles by the nerves. He coined the term animal electricity to describe the muscle-activating force. One hundred and fifty years after he determined that muscle activation is generated by an electric fluid carried by the nerves, mathematician N. Wiener studied an artificial hand controlled by an electrical current produced in the muscles. This book discusses new developments, procedures and applications of electromyography.

Knee - Current Concepts in Kinematics, Injury Types & Treatment Options (Hardcover, New): Randy Mascarenhas Knee - Current Concepts in Kinematics, Injury Types & Treatment Options (Hardcover, New)
Randy Mascarenhas
R3,974 Discovery Miles 39 740 Ships in 12 - 17 working days

Knee injuries are common occurrences that affect the young active population and can lead to subsequent long term joint degeneration. This book provides an overview of current research examining knee injury mechanisms, prevention, and treatment options. Detailed discussions are included related to current treatment options for ACL injury, PCL injury, meniscal tears, patellofemoral instability, and combined knee pathology. Additionally, current advances in tissue engineering in ACL reconstruction and results following transphyseal ACL reconstruction in adolescents are examined. Furthermore, biomechanical studies and computerised modelling techniques are highlighted as methods for determining the mechanisms and sequelae of knee injuries, thus aiding in the development of injury prevention programs.

Bone Morphogenetic Proteins - New Research (Hardcover, New): Anja Nohe Bone Morphogenetic Proteins - New Research (Hardcover, New)
Anja Nohe
R5,026 Discovery Miles 50 260 Ships in 12 - 17 working days

This book summarises the new advances in bone morphogenetic protein (BMP) research. It introduces current concepts and dogmas and details clinical applications. It especially highlights the potential of BMPs as powerful therapeutics regulating diverse functions during embryonic development, stem cell differentiation and organ physiology. This book also challenges current knowledge and introduces new research questions and mechanisms. These mechanisms range from crosstalk on the molecular level to the role of BMPs in the urethra and exocrine glands. Additionally, it describes the drawback and advantages of BMPs currently used in clinical applications.

Sarcoma - Symptoms, Causes & Treatments (Hardcover): Eric J. Butler Sarcoma - Symptoms, Causes & Treatments (Hardcover)
Eric J. Butler
R2,910 Discovery Miles 29 100 Ships in 12 - 17 working days

Sarcomas are a group of rare malignant tumors that constitute less than 1% of all cancers, arising from the mesenchymal system. About 80% originate in soft tissue (muscle, nerves, joints, blood vessels, deep skin tissues, and fat), while the remainder originate in bone and cartilage. In this book, the authors present topical research on the symptoms, causes and treatments of sarcoma. Some of the topics discussed include clinical-histopathologic diagnosis of the kaposi's sarcoma; ovarian sarcoma in mice; advances in chondrosarcoma treatment; the potential of suicide plus immune gene therapy for treating osteosarcoma; new concepts of limb salvage surgery in musculoskeletal sarcomas with acridine orange therapy; the role of surgery in children with head and neck rhabdomyosarcoma and gastrointestinal kaposi's sarcoma. (Imprint: Nova biomedical)

10 Best Questions for Living with Fibromyalgia - The Script You Need to Take Control of Your Health (Paperback): Dede Bonner,... 10 Best Questions for Living with Fibromyalgia - The Script You Need to Take Control of Your Health (Paperback)
Dede Bonner, Wood
R504 Discovery Miles 5 040 Ships in 10 - 15 working days

An indispensable resource that empowers fibromyalgia patients to take charge of a debilitating disease and get the health care they deserve.
Fibromyalgia--a painful, exhausting, and often misdiagnosed disease--affects up to 12 million Americans (90 percent of them women). And because many health care professionals are still learning how to diagnosis and treat its confusing symptoms, patients living with the disorder must become proactive and informed consumers for their own health. The expert advice found within The 10 Best Questions(TM) for Living with Fibromyalgia gives readers the answers they need to get the best care possible and enjoy a more normal life. This essential book provides the Best Questions that patients should ask their doctors, partners, children, and friends, accompanied by the "best answers" drawn from cutting edge research and extensive interviews with the top experts in the field. There are chapters on what to ask about your diagnosis, test results, second opinions, for ongoing disease management, to lose weight, get more sleep, and to make other healthy lifestyle changes. This practical and holistic book also offers Best Questions and advice for fibromyalgia patients for their relationships with partners, children, friends to ensure emotional, financial, and spiritual health. Each chapter concludes with The Magic Question(TM), the one crucial question most people never think to ask until it's too late.

Skeletal Muscle Circulation (Paperback): Ronald Korthuis Skeletal Muscle Circulation (Paperback)
Ronald Korthuis
R1,301 Discovery Miles 13 010 Ships in 10 - 15 working days

The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated (exercise hyperemia) to meet the increased demand for oxygen and other substrates during exercise, mechanisms underlying the beneficial effects of regular physical activity on cardiovascular health, the regulation of transcapillary fluid filtration and protein flux across the microvascular exchange vessels, and the role of changes in the skeletal muscle circulation in pathologic states. Skeletal muscle is unique among organs in that its blood flow can change over a remarkably large range. Compared to blood flow at rest, muscle blood flow can increase by more than 20-fold on average during intense exercise, while perfusion of certain individual white muscles or portions of those muscles can increase by as much as 80-fold. This is compared to maximal increases of 4- to 6-fold in the coronary circulation during exercise. These increases in muscle perfusion are required to meet the enormous demands for oxygen and nutrients by the active muscles. Because of its large mass and the fact that skeletal muscles receive 25% of the cardiac output at rest, sympathetically mediated vasoconstriction in vessels supplying this tissue allows central hemodynamic variables (e.g., blood pressure) to be spared during stresses such as hypovolemic shock. Sympathetic vasoconstriction in skeletal muscle in such pathologic conditions also effectively shunts blood flow away from muscles to tissues that are more sensitive to reductions in their blood supply that might otherwise occur. Again, because of its large mass and percentage of cardiac output directed to skeletal muscle, alterations in blood vessel structure and function with chronic disease (e.g., hypertension) contribute significantly to the pathology of such disorders. Alterations in skeletal muscle vascular resistance and/or in the exchange properties of this vascular bed also modify transcapillary fluid filtration and solute movement across the microvascular barrier to influence muscle function and contribute to disease pathology. Finally, it is clear that exercise training induces an adaptive transformation to a protected phenotype in the vasculature supplying skeletal muscle and other tissues to promote overall cardiovascular health. Table of Contents: Introduction / Anatomy of Skeletal Muscle and Its Vascular Supply / Regulation of Vascular Tone in Skeletal Muscle / Exercise Hyperemia and Regulation of Tissue Oxygenation During Muscular Activity / Microvascular Fluid and Solute Exchange in Skeletal Muscle / Skeletal Muscle Circulation in Aging and Disease States: Protective Effects of Exercise / References

Rheumatoid Arthritis (Paperback, New): Michael H. Weisman Rheumatoid Arthritis (Paperback, New)
Michael H. Weisman
R1,689 Discovery Miles 16 890 Ships in 10 - 15 working days

Rheumatoid arthritis is a common but often debilitating disorder. Given the intricate and challenging nature of treating rheumatoid arthritis, it is imperative to educate physicians on the disease's initial symptoms and complications, as well as to provide accurate and up-to-date information regarding effective treatment. Designed to help eradicate misconceptions concerning rheumatoid arthritis and its treatment, this concise volume helps clinicians to understand and then effectively diagnose and treat patients with the condition.
Part of the Oxford American Rheumatology Library, this concise guide serves as a practical, user-friendly reference for rheumatologists and other healthcare professionals. The book provides an overview of rheumatoid arthritis, including its epidemiology, symptoms, signs, and pathophysiology. Using the most current information available, the author evaluates both traditional and innovative treatment methods. A thorough glossary defines key terms and the appendix includes related resource information - associations, journals and doctors/researchers - all devoted to the study and treatment of rheumatoid arthritis.

Oxford Handbook of Orthopaedic and Trauma Nursing (Paperback): Rebecca Jester, Julie Santy, Jean Rogers MSC Oxford Handbook of Orthopaedic and Trauma Nursing (Paperback)
Rebecca Jester, Julie Santy, Jean Rogers MSC
R766 Discovery Miles 7 660 Ships in 2 - 4 working days

Providing busy practitioners with the information they need to deliver care, and nursing students with a clear overview of the field, the Oxford Handbook of Orthopaedic and Trauma Nursing is an easily accessible, practical, and comprehensive guide to all aspects of practice. Orthopaedics and trauma is a major sector of acute hospital and community care, and one in which nurses and Allied Health Professionals play a pivotal role, covering the continuum from birth to death and managing everything from emergency care to rehabilitation and discharge. This handbook is the ideal companion, presenting a broad spectrum of care and treatment across trauma and orthopaedics. It provides an evidence-based synopsis of contemporary care and treatment as well as an applied assessment framework for those wishing to advance their practice.
Clearly laid-out, well-illustrated and written in a readable, note-based style, the Oxford Handbook of Orthopaedic and Trauma Nursing brings together the authors' many years of collective experience in one easy-to-use format which the practitioner and student won't want to be without.

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