Micro/nano-mechanical systems are a crucial part of the modern world providing a plethora of sensing and actuation functionalities used in everything from the largest cargo ships to the smallest hand-held electronics; from the most advanced scientific and medical equipment to the simplest household items. Over the past few decades, the processes used to produce these devices have improved, supporting dramatic reductions in size, but there are fundamental limits to this trend that require a new production paradigm. The 2004 discovery of graphene ushered in a new era of condensed matter physics research, that of two-dimensional materials. Being only a few atomic layers thick, this new class of materials exhibit unprecedented mechanical strength and flexibility and can couple to electric, magnetic and optical signals. Additionally, they can be combined to form van der Waals heterostructures in an almost limitless number of ways. They are thus ideal candidates to reduce the size and extend the capabilities of traditional micro/nano-mechanical systems and are poised to redefine the technological sphere. This thesis attempts to develop the framework and protocols required to produce and characterise micro/nano-mechanical devices made from two-dimensional materials. Graphene and its insulating analogue, hexagonal boron nitride, are the most widely studied materials and their heterostructures are used as the test-bed for potential device architectures and capabilities. Interlayer friction, electro-mechanical actuation and surface reconstruction are some of the key phenomena investigated in this work.

Up to 40 volumes are planned for this concise monograph series, which focuses on the implementation of various engineering principles in the conception, design, development, analysis and operation of biomedical, biotechnological and nanotechnology systems and applications. The smartness of nano-materials is attributed to their nanoscale and subsequently unique physicochemical properties and their use in glucose sensing has been aimed at improving performance, reducing cost and miniaturizing the sensor and its associated instrumentation. So far, portable (handheld) glucose analysers were introduced for hospital wards, emergency rooms and physicians' offices; single-use strip systems achieved nanolitre sampling for painless and accurate home glucose monitoring; advanced continuous monitoring devices having 2 to 7 days operating life are in clinical and home use; and continued research efforts are being made to develop and introduce increasingly advanced glucose monitoring systems for health as well as food, biotechnology, cell and tissue culture industries. Nanomaterials have touched every aspect of biosensor design and this chapter reviews their role in the development of advanced technologies for glucose sensing, and especially for diabetes. Research shows that overall, nanomaterials help address the problems with conventional optical and electrochemical biosensors, by enhancing the preferential detection of glucose or its oxidation products through better electron transfer kinetics, sensitivity and response time, while lowering the operating over-voltages for energy efficiency and avoid interference. The reproducible production of nano-materials and nano-structures at low cost is vital for the successful development of nano-technologies for glucose sensing. Several products, especially, home glucose monitoring devices, use nano-materials, but the need for reliable long-term CGM is still unmet. Nano-materials and nano-technologies have an important role in achieving the long-awaited CGM technology.

This book provides a broad introductory survey of this remarkable field, aiming to establish and clearly differentiate its physical principles, and also to provide a snapshot portrait of many of the most prominent current applications. Primary emphasis is placed on developing an understanding of the fundamental photonic origin behind the mechanism that operates in each type of effect. To this end, the first few chapters introduce and develop core theory, focusing on the physical significance and source of the most salient parameters, and revealing the detailed interplay between the key material and optical properties. Where appropriate, both classical and photonic (quantum mechanical) representations are discussed. The number of equations is purposely kept to a minimum, and only a broad background in optical physics is assumed. With copious examples and illustrations, each of the subsequent chapters then sets out to explain and exhibit the main features and uses of the various distinct types of mechanism that can be involved in optical nanomanipulation, including some of the very latest developments. To complete the scene, we also briefly discuss applications to larger, biological particles. Overall, this book aims to deliver to the non-specialist an amenable introduction to the technically more advanced literature on individual manipulation methods. Full references to the original research papers are given throughout, and an up-to-date bibliography is provided for each chapter, which directs the reader to other selected, more specialised sources.

This volume is the latest of the "Kirchberg-Proceedings". The previous 11 International Winterschools on Electronic Properties of Novel Materials, all held in Kirchberg, Austria, were devoted to conducting polymers, high temperature superconductors, fullerenes, and carbon nanotubes. Fullerenes and nanotubes are still in the center of interest, but the topic of the school and the proceedings is molecular nanostructures in general. The organizers have attempted to treat carbon nanostructures as a special case of molecular nanostructures, which also include silicon clusters, gold clusters, vanadium oxide tubes, and many others. The Winterschool provides a platform for reviewing and discussing new developments in the field of molecular nanostructures and their applications. Materials discussed include fullerenes, fullerene-derived structures, carbonaceous nanotubes, non-carbonaceous nanotubes, layer by layer systems, molecular clusters, new phases of carbon, endohedral compounds and related materials. The book aims to give an overview of the current status of fullerenes, carbon-nanotubes and related molecular nanostructures. The majority of the contributions present the latest results of experiments and calculations conducted in the field. However, about a dozen contain some degree of instructional material which even newcomers will benefit from.

Nanoscience stands out for its interdisciplinarity. Barriers between disciplines disappear and the fields tend to converge at the very smallest scale, where basic principles and tools are universal. Novel properties are inherent to nanosized systems due to quantum effects and a reduction in dimensionality: nanoscience is likely to continue to revolutionize many areas of human activity, such as materials science, nanoelectronics, information processing, biotechnology and medicine. This textbook spans all fields of nanoscience, covering its basics and broad applications. After an introduction to the physical and chemical principles of nanoscience, coverage moves on to the adjacent fields of microscopy, nanoanalysis, synthesis, nanocrystals, nanowires, nanolayers, carbon nanostructures, bulk nanomaterials, nanomechanics, nanophotonics, nanofluidics, nanomagnetism, nanotechnology for computers, nanochemistry, nanobiology, and nanomedicine. Consequently, this broad yet unified coverage addresses research in academia and industry across the natural scientists. Didactically structured and replete with hundreds of illustrations, the textbook is aimed primarily at graduate and advanced-undergraduate students of natural sciences and medicine, and their lecturers.

The Symposium on Magnetic Ultrathin Films, Multilayers and
Surfaces, hosted by the European Materials Research Society, was
held at the Palais de la Musique et des Congre in
Strasbourg, France on June 4-7, 1996. Its central theme was the
relationship of magnetic properties and device performance to
structure at the nano and micrometer length scale. Research on
the magnetism of surfaces, ultrathin films and multilayers has
increased dramatically during recent years. This development was
triggered by the discovery of coupling between ferromagnetic
layers across nonmagnetic spacer layers and of the giant
magnetoresistance effect in systems of reduced dimension using
various micro and nanofabrication techniques has become a subject
of special interest. It is certainly the promising application
potential of these effects in new magnetic recording device
geometries which causes this intensive research, which is done
both by companies and at universities and research
institutes.

A selection of invited and contributed papers
presented at the Symposium and accepted for publication is
contained in this volume. The contents of these proceedings are
organized into seven sections.

A. Nanowires, Nanoparticles,
Nanostructuring

B. Ultrathin Films and Surfaces,
Characterization

C. Giant Magnetoresistance

D. Coupling,
Tunneling

E. Growth, Structure, Magnetism

F. Growth,
Structure, Magnetoresistance

G. Coupling, Magnetic processes,
Magneto-optics.

The first four sections contain invited and
oral contributed papers in the listed research domains, while the
last three sections contain the contributions presented during
three large poster sessions.

The title "Nano Biotechnology for Biomedical and Diagnostics Research" will address research aspects related to nanomaterial in imaging and biological research, nanomaterials as a biosensing tool, DNA nanotechnology, nanomaterials for drug delivery, medicinal and therapeutic application and cytotoxicity of nanomaterials. These topics will be covered by 16 different manuscripts. Amongst the authors that will contribute to the book are major scientific leaders such as S. Weiss - UCLA, I. Willner, and G. Golomb -- HUJI, S. Esener - UCSD, E.C. Simmel - Tech. Univ. Munchen, I. Medintz -- NRL, N. Hildebrandt - Universit Paris and more. The manuscripts in the book intend to present specifically biological, diagnostics and medical problems with their potential solution by nano technology or materials. In this respect this book is unique, since it would arise from the biological problems to the nano technology possible solution and not vice versa.

Bringing together nanoscience with stem cell and bacterial cell biology, this thesis is truly interdisciplinary in scope. It shows that the creation of superparamagnetic nanoparticles inside a protein coat, followed by chemical functionalisation of the protein surface, provides a novel methodology for cell magnetisation using incubation times as short as one minute. Crucially, stem cell proliferation and multi-lineage differentiation capacity is not impaired after labelling. Due to the unspecific labelling mechanism, this thesis also shows that the same magnetic protein nanoparticles can be used for rapid bacterial magnetisation. Thus, it is possible to magnetically capture and concentrate pathogens from clinical samples quickly and highly efficiently.

Building on the success of its predecessor, Carbon Nanotubes: Synthesis, Structure, Properties and Applications, this second volume focuses on those areas that have grown rapidly in the past few years. Contributing authors reflect the multidisciplinary nature of the book and are all leaders in their particular areas of research. Among the many topics they cover are graphene and other carbon-like and tube-like materials, which are likely to affect and influence developments in nanotubes within the next five years. Extensive use of illustrations enables you to better understand and visualize key concepts and processes.

This multi-authored book provides a comprehensive overview of the latest developments in porous CO2 capture materials, including ionic liquid derived carbonaceous adsorbents, porous carbons, metal-organic frameworks, porous aromatic frameworks, micro porous organic polymers. It also reviews the sorption techniques such as cyclic uptake and desorption reactions and membrane separations. In each category, the design and fabrication, the comprehensive characterization, the evaluation of CO2 sorption/separation and the sorption/degradation mechanism are highlighted. In addition, the advantages and remaining challenges as well as future perspectives for each porous material are covered.

This book is aimed at scientists and graduate students in such fields as separation, carbon, polymer, chemistry, material science and technology, who will use and appreciate this information source in their research. Other specialists may consult specific chapters to find the latest, authoritative reviews.

Dr. An-Hui Lu is a Professor at the State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, China.

Dr. Sheng Dai is a Corporate Fellow and Group Leader in the Chemical Sciences Division at Oak Ridge National Laboratory (ORNL) and a Professor of Chemistry at the University of Tennessee, USA."

This book introduces an innovative and high-efficiency technology for mechanical energy harvesting. The book covers the history and development of triboelectric nanogenerators, basic structures, working principles, performance characterization, and potential applications. It is divided into three parts: Part A illustrates the fundamental working modes of triboelectric nanogenerators with their prototype structures and theoretical analysis; Part B and Part C introduce two categories of applications, namely self-powered systems and self-powered active sensors. The book will be an ideal guide to scientists and engineers beginning to study triboelectric nanogenerators or wishing to deepen their knowledge of the field. Readers will be able to place the technical details about this technology in context, and acquire the necessary skills to reproduce the experimental setups for fabrication and measurement.

Personalized health care to manage diseases and optimized treatment is crucial for everyone to maintain health quality. Significant efforts have been made to design and develop novel nano-enabling therapeutic strategies to cure and monitor diseases for personalized health care. As state-of-the-art, various strategies have been reported to develop personalized nanomedicine to combat against target diseases with no side effects. In this book proposal, we are trying to describe fundamentals of personalized nanomedicine, novel nanomaterials for drug delivery, role of nanotechnology for efficient therapeutics approach, nano-pharmacology, targeted CNS drug delivery, stimuli responsive drug release and nanotechnology for diseases management. This book would serve as a platform for new scholars to understand state-of-the-art of nanotechnology for therapeutics and designing their future research to develop effective personalized nanomedicine against targeted diseases. As of now, various studies have been reported to design and develop nanomedicines of higher efficacy but unfortunately, such products are up to laboratory research only and need to be well-tested using pre-clinical or human models. Our book would be a call for experts to explore multidisciplinary research for developing novel and efficient approaches to explore smart efficient nanocarriers for site-specific on-demand controlled drug delivery to combat against targeted diseases to personalized health care.

Transmission electron microscopy (TEM) is now recognized as a crucial tool in materials science. This book, authored by a team of expert Chinese and international authors, covers many aspects of modern electron microscopy, from the architecture of novel electron microscopes, advanced theories and techniques in TEM and sample preparation, to a variety of hands-on examples of TEM applications. Volume I concentrates on the newly developed concepts and methods which are making TEM a powerful and indispensible tool in materials science.

This comprehensive book covers flexible fiber-shaped devices in the area of energy conversion and storage. The first part of the book introduces recently developed materials, particularly, various nanomaterials and composite materials based on nanostructured carbon such as carbon nanotubes and graphene, metals and polymers for the construction of fiber electrodes. The second part of the book focuses on two typical twisted and coaxial architectures of fiber-shaped devices for energy conversion and storage. The emphasis is placed on dye-sensitized solar cells, polymer solar cells, lithium-ion batteries, electrochemical capacitors and integrated devices. The future development and challenges of these novel and promising fiber-shaped devices are summarized in the final part. This book is the first to introduce fiber-shaped electronic devices, which offer many fascinating advantages compared with the conventional planar structure. It is particularly designed to review the state-of-art developments in fiber-shaped devices for energy conversion and storage. The book will provide a valuable resource for researchers and students working in a wide variety of fields such as advanced materials, new energy, electrochemistry, applied physics, nanoscience and nanotechnology, and polymer science and engineering. Huisheng Peng, PhD, is a Professor and Associate Chair of the Department of Macromolecular Science and PI of the Laboratory of Advanced Materials, Fudan University, Shanghai, China.

Transmission electron microscopy (TEM) is now recognized as a crucial tool in materials science. This book, authored by a team of expert Chinese and international authors, covers many aspects of modern electron microscopy, from the architecture of novel electron microscopes, advanced theories and techniques in TEM and sample preparation, to a variety of hands-on examples of TEM applications. Volume II illustrates the important role that TEM is playing in the development and characterization of advanced materials, including nanostructures, interfacial structures, defects, and macromolecular complexes.

Heat transfer laws for conduction, radiation and convection change when the dimensions of the systems in question shrink. The altered behaviours can be used efficiently in energy conversion, respectively bio- and high-performance materials to control microelectronic devices. To understand and model those thermal mechanisms, specific metrologies have to be established. This book provides an overview of actual devices and materials involving micro-nanoscale heat transfer mechanisms. These are clearly explained and exemplified by a large spectrum of relevant physical models, while the most advanced nanoscale thermal metrologies are presented.

This book provides a comprehensive description of microsensors for mechanical quantities (flow, pressure, force, inertia) fabricated by silicon micromachining. Since the design of such sensors requires interdisciplinary teamwork, the presentation is made accessible to engineers trained in electrical and mechanical engineering, physics and chemistry. The reader is guided through the micromachining fabrication process. A chapter on microsensor packaging completes the discussion of technological problems. The description of the basic physics required for sensor design includes the mechanics of deformation and the piezoresistive transduction to electrical signals. There is also a comprehensive discussion of resonant sensors, the hydrodynamics and heat transfer relevant for flow sensors, and, finally, electronic interfacing and readout circuitry. Numerous up-to-date case studies are presented, together with the working, fabrication and design of the sensors.

The application of nanotechnology in different consumer products has delivered new products with highly desirable properties, but at same time has opened a new window for a wide group of emerging contaminants and a new type of human exposure which needs to be assessed.

Most of the current human toxicological information on nanomaterials comes from nano-sized particles in air, and their effects via inhalation. Other routes of human exposure, such as water and food, and the effects on human health and the environment have been less studied. It is the recent research in these areas that is highlighted here in one of the first books covering the analysis and ecotoxicological evaluation of nanomaterials in food and the environment, with both matrices being of considerable interest. In addition to providing a global summary of recent research, this book shows how widely used chromatographic and spectroscopic methods can be added to the analytical arsenal of microscopic techniques that have commonly been used to characterize nanomaterials.
Describes the analytical techniques used to characterize nanomaterials and their applications in environmental or food samplesIncludes analysis and ecotoxicological evaluation of nanomaterials in food and environmental matricesTakes a detailed look at the research on emerging fields of human exposure to nanomaterials and their environmental risks

This is the first book about functional nanostructures. Nanocrystalline materials exhibit outstanding properties and represent a new class of structural materials having a wide range of applications. In particular, there is considerable interest in developing nanocrystalline materials to be used as functional materials in aerospace applications, automotive industry, wear applications, etc. Future progress in these high technological applications of nanocrystalline materials depends on development of new methods of their fabrication and understanding of the underlying nano-scale and interface effects causing their unique mechanical properties.

This book covers the latest research on porous materials at the submicron scale and inspires readers to better understand the porosity of materials, as well as to develop innovative new materials. A comprehensive range of materials are covered, including carbon-based and organic-based porous materials, porous anodic alumina, silica, and titania-based sol-gel materials. The fabrication, characterization, and applications of these materials are all explored, with applications ranging from sensors, thermoelectrics, catalysis, energy storage, to photovoltaics. Also of practical use for readers are chapters that describe the basics of porous silicon fabrication and its use in optical sensing and drug delivery applications; how thermal transport is affected in porous materials; how to model diffusion in porous materials; and a unique chapter on an innovative spectroscopic technique used to characterize materials' porosity. This is an ideal book for graduate students, researchers, and professionals who work with porous materials.

Less than twenty years ago photolithography and medicine were total strangers to one another. They had not yet met, and not even looking each other up in the classi?eds. And then, nucleic acid chips, micro?uidics and microarrays entered the scene, and rapidly these strangers became indispensable partners in biomedicine. Asrecentlyastenyearsagothenotionofapplyingnanotechnologytothe?ghtagainstd- ease was dominantly the province of the ?ction writers. Thoughts of nanoparticle-vehicled deliveryoftherapeuticalstodiseasedsiteswereanexerciseinscienti?csolitude,andgrounds for questioning one's ability to think "like an established scientist". And today we have nanoparticulate paclitaxel as the prime option against metastatic breast cancer, proteomic pro?lingdiagnostictoolsbasedontargetsurfacenanotexturing,nanoparticlecontrastagents for all radiological modalities, nanotechnologies embedded in high-distribution laboratory equipment, and no less than 152 novel nanomedical entities in the regulatory pipeline in the US alone. Thisisatransformingimpact,byanymeasure,withclearevidenceoffurtheracceleration, supported by very vigorous investments by the public and private sectors throughout the world. Even joining the dots in a most conservative, linear fashion, it is easy to envision scenarios of personalized medicine such as the following: patient-speci?c prevention supplanting gross, faceless intervention strategies; early detection protocols identifying signs of developing disease at the time when the disease is most easily subdued; personally tailored intervention strategies that are so routinely and inexpensively realized, that access to them can be secured by everyone; technologies allowing for long lives in the company of disease, as good neighbors, without impairment of the quality of life itself.

A compendium of novel information on molecular-scale science and the application of nanocarbon, nanosilicon and biopolymer integrated nanosystems.

During the 20th century, molecular-scale science and nanotechnology developed rapidly, leading to the construction of innovative materials - nanosystens from molecules (fullerenes), supramolecules (nanotubes, peapods, polymers, biopolymers (DNA, protein and their complexes) and semiconductor nanoparticles (nano-Si, SiOx, Si/SiGe dots, metal nanowires). This book presents exciting new developments of the early 21st century. Significant progress has been made in nanotechnology of building blocks for integrated nanosystems, single and assembled molecules, nanoparticles characterisation, and multifunctional applications of nanosystems.

The realisation and the application of novel multifunctional nanosystems in electronics, optics, biomedicine (nano-bioelectronic devices based on DNA and proteins, silicon nanocrystal memory devices, monolithically integrated silicon photonics, nanocapsules, biosensor nanosystems) are described by well known experts.

A presentation and discussion of the most recent advances in the field by the world's leading experts. Topics dealt with include new organic metals with quasi-two-dimensional structure, new organic superconductors, conducting and magnetic hybrid organic-inorganic materials, and highly conducting organic composites. Also reported are very interesting, significant results on optically controllable gratings in liquid crystals and polymers, organic electroluminescent materials, functionalised polymers and photonics, and nonlinear optics. Some new, fascinating fullerene derivatives and organic and metallic clusters are also presented. The chemical design of logic gates and molecular logic machines and the analysis of the roles of defects in clusters are attracting great interest. The properties of semiconducting quantum wires, electronic transport through magnetic molecular nanostructure and electronic transport properties of nanostructures containing both ferromagnetic and superconductors are also presented and discussed.

Technology of Quantum Devices offers a multi-disciplinary overview of solid state physics, photonics and semiconductor growth and fabrication.

Readers will find up-to-date coverage of compound semiconductors, crystal growth techniques, silicon and compound semiconductor device technology, in addition to intersubband and semiconductor lasers. Recent findings in quantum tunneling transport, quantum well intersubband photodetectors (QWIP) and quantum dot photodetectors (QWDIP) are described, along with a thorough set of sample problems.

This book describes the design, construction, and characterization of a new type of aberration-corrected, neutral-atom lens. Atom beam control plays a crucial role in many different fields, ranging from fundamental physics research and materials science to applied nanotechnology. Despite this, atom-optical elements like lenses and mirrors remain relatively underdeveloped compared to their counterparts in other optics fields. Although aberration correction is addressed quite comprehensively in photon and electron lenses, no credible research efforts have yet produced the same technology for neutral atoms. It reports on progress towards a neutral atom imaging device that will be useful in a range of applications, including nanofabrication and surface microscopy. It presents a novel technique for improving refractive power and correcting chromatic aberration in atom lenses based on a fundamental paradigm shift from continuous, two-dimensional focusing to a pulsed, three-dimensional approach. Simulations of this system suggest that it will pave the way towards the long-sought goal of true atom imaging on the nanoscale. The book further describes the construction of a prototype lens, and shows that all of the technological requirements for the proposed system are easily satisfied. Using metastable neon from a supersonic source, the prototype was characterized for three different focal lengths and a diverse range of apertures. Despite some manufacturing imperfections, lower distortion and higher resolution than has been shown in any previous hexapole lens was observed. Comparison with simulations corroborates the underlying theory and encourages further refinement of the process.