This volume presents a comprehensive perspective on the global scientific, technological, and societal impact of nanotechnology since 2000, and explores the opportunities and research directions in the next decade to 2020. The vision for the future of nanotechnology presented here draws on scientific insights from U.S. experts in the field, examinations of lessons learned, and international perspectives shared by participants from 35 countries in a series of high-level workshops organized by Mike Roco of the National Science Foundation (NSF), along with a team of American co-hosts that includes Chad Mirkin, Mark Hersam, Evelyn Hu, and several other eminent U.S. scientists. The study performed in support of the U.S. National Nanotechnology Initiative (NNI) aims to redefine the R&D goals for nanoscale science and engineering integration and to establish nanotechnology as a general-purpose technology in the next decade. It intends to provide decision makers in academia, industry, and government with a nanotechnology community perspective of productive and responsible paths forward for nanotechnology R&D.

At the heart of this thesis is the young field of free electron laser science, whose experimental and theoretical basics are described here in a comprehensible manner. Extremely bright and ultra short pulses from short wavelength free-electron lasers (FELs) have recently opened the path to new fields of research. The x-ray flashes transform all matter into highly excited plasma states within femtoseconds, while their high spatial and temporal resolution allows the study of fast processes in very small structures. Even imaging of single molecules may be within reach if ultrafast radiation damage can be understood and brought under control. Atomic clusters have proven to be ideal model systems for light-matter interaction studies in all wavelength regimes, being size scalable, easy-to-produce gas phase targets with a simple structure. With FELs, "single cluster imaging and simultaneous ion spectroscopy" makes possible experiments under extremely well defined initial conditions, because the size of the cluster and the FEL intensity can be extracted from the scattering images. For the first time large xenon clusters up to micron radius were generated. Their single cluster scattering images were analyzed for cluster morphology and traces of the ultrafast plasma built-up during the femtosecond FEL pulse. The simultaneously measured single cluster ion spectra yield unprecedented insight into the ion dynamics following the interaction. The results will feed both future experimental effort and theoretical modeling.

This thesis focuses on the controlled synthesis of Pt-Ni bimetallic nanoparticles and the study of their catalytic properties. It discusses in detail the nucleation mechanism and the growth process of bimetallic systems, which is vital for a deeper understanding of the design of bimetallic catalysts. The author presents four pioneering studies: (1) syntheses of water-soluble octahedral, truncated octahedral, and cubic Pt-Ni nanocrystals and the study of their structure-activity relationship in model hydrogenation reactions; (2) a strategy for designing a concave Pt-Ni alloy using controllable chemical etching; (3) defect-dominated shape recovery of nanocrystals, which is a new synthesis strategy for trimetallic catalysts; (4) a sophisticated construction of Au islands on Pt Ni, which is an ideal trimetallic nanoframe catalyst. This thesis inspires researchers working in materials, catalysis as well as other interdisciplinary areas.

Fourth volume of a 40volume series on nano science and nanotechnology, edited by the renowned scientist Challa S.S.R. Kumar. This handbook gives a comprehensive overview about Surface Science Tools for Nanomaterials Characterization. Modern applications and state-of-the-art techniques are covered and make this volume an essential reading for research scientists in academia and industry.

Unlike most natural colours that are based on pigment absorption, the striking iridescent and intense colouration of many butterflies, birds or beetles stems from the interaction of light with periodic sub-micrometer surface or volume patterns, so called "photonic structures". These "structural colours" are increasingly well understood, but they are difficult to create artificially and exploit technologically. In this thesis the field of natural structural colours and biomimetic photonic structures is covered in a wide scope, ranging from plant photonics to theoretical optics. It demonstrates diffractive elements on the petal surfaces of many flowering plant species; these form the basis for the study of the role of structural colours in pollinator attraction. Self-assembly techniques, combined with scale able nanofabrication methods, were used to create complex artificial photonic structures inspired by those found in nature. In particular, the colour effect of a Papilio butterfly was mimicked and, by variation of its design motive, enhanced. All photonic effects described here are underpinned by state-of-the-art model calculations.

This volume is based on some representative contributions presented in the wo- shop: "Trends in nanophysics: theory, experiment, technology," which took place in Sibiu, Romania, 23-29 August 2009, being organized by ICTP-Trieste, IAEA, IFIN-HH - Bucharest and ULB - Sibiu. The aim of this workshop was to faci- tate experts and active researchers to exchange ideas and information on the most recent results in nanophysics and nanotechnology. It was also an opportunity for young researchers and for researchers from developing countries to enlarge their knowledge and to approach new themes in this area. In fact, the articles contained in this book represent written and enriched versions of the workshop oral presentations. The topics covered by them are the following: 1. Ordered atomic-scale structures 2. Nanowires: growth and properties 3. Transport phenomena in nanostructures 4. Optical properties of nanostructures 5. Magnetic nanophases; magnetic and non-magnetic nanocomposites 6. Nano uids and ows at nanoscale 1 Ordered Atomic-Scale Structures The quest of a reliable method for fabricating ordered atomic-scale structures is a prerequisite for future atomic-scale technology - the ultimate goal of nanosciences.

Yanfei Shen and Takashi Nakanishi Exotic Self-Organized Fullerene Materials Based on Uncommon Hydrophobic Amphiphilic Approach Yuming Zhao and Guang Chen C60 Fullerene Amphiphiles as Supramolecular Building Blocks for Organized and Well-Defined Nano scale Objects Anna Troeger, Vito Sgobba and Dirk M. Guldi Multilayer Assembly for Solar Energy Conversion Delphine Felder-Flesch Self- or Induced Organization of 60]Fullerene Hexakisadducts Andres de la Escosura, Olga Trukhina, and Tomas Torres Dual Role of Phthalocyanines in Carbon Nano structure-Based Organic Photovoltaics Riccardo Marega, Davide Giust and Davide Bonifazi Supramolecular Chemistry of Carbon Nano tubes at Interfaces: Toward Applications Stephanie Frankenberger, Johanna A. Januszewski and Rik R. Tykwinski Oligomers from sp-Hybridized Carbon: Cumulenes and Polyynes."

The very first major reference text on this topic, this book provides a unique collection of articles reviewing the state of the art in the field. It gives particular emphasis to emerging technologies, from bioengineering and bio-tissues to nanotechnology. The integration of the different topics is presented via a combination of theoretical and applied methodology to provide a self-contained major reference that is appealing to both the scientist and the engineer.

This book brings together the recent cutting-edge work on computational methods in photonics and their applications. The latest advances in techniques such as the Discontinuous Galerkin Time Domain method, Finite Element Time Domain method, Finite Difference Time Domain method as well as their applications are presented. Key aspects such as modelling of non-linear effects (Second Harmonic Generation, lasing in fibers, including gain nonlinearity in metamaterials), the acousto-optic effect, and the hydrodynamic model to explain electron response in nanoplasmonic structures are included. The application areas covered include plasmonics, metamaterials, photonic crystals, dielectric waveguides, fiber lasers. The chapters give a representative survey of the corresponding area.

This second volume of the series Lecture Notes in Applied and Computational Mechanics is the second part of the compendium of reviewed articles presented at the 11th EUROMECH-MECAMAT conference entitled "Mechanics of microstructured solids: cellular materials, fibre reinforced solids and soft tissues," which took place in Torino (Italy) in March 10-14, 2008, at the Museo Regional delle Scienze. This EUROMECH-MECAMAT conference was jointly organized by the Dipartimento di Matematica dell'Universita di Torino, Italy and the INPL Institute (LEMTA, Nancy-Universite, France). Prof. Franco Pastrone and Prof. Jean-Francois Ganghoffer were the co-chairmen.

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

This book discusses current trends and potential areas of nanotechnology applications in dental materials. Dentistry is undergoing yet another change to benefit mankind via the discipline of nanodentistry. A variety of nanostructures such as nanorobots, nanospheres, nanofibers, nanorods, etc., have been studied for various applications in dentistry and medicine. Preventive dentistry has also utilized nanodentistry to develop the nanomaterials for inclusion in a variety of oral health-care products. Methods to prevent and combat dental problems have been devised, discussed, and implemented since ancient times; however, there is a constant need for improved tools and techniques. This book is relevant academically for undergraduate and post-graduate dental students, dental practitioners, researchers, and faculties of dental universities, as this book explores the application of various nanobiomaterials in dentistry, discusses current research in dental nanomaterials and potential future areas of interest, and examines the use of nanotechnology in various fields of dentistry.

This book presents highlighted results coming up from NanoCarbon2011, a Brazilian Carbon event. The topics cover the latest advances in Brazilian basic and applied research related to different carbon materials. The chapters address reviews on their fundamental and outstanding properties and describe various classes of new promising high-tech applications for carbon materials.

Size effect in structures has been taken into consideration over the last years. In comparison with coatings with micrometer-ranged thickness, nanostructured coatings usually enjoy better and appropriate properties, such as strength and resistance. These coatings enjoy unique magnetic properties and are used with the aim of producing surfaces resistant against erosion, lubricant system, cutting tools, manufacturing hardened sporadic alloys, being resistant against oxidation and corrosion.

This book reviews researches on fabrication and classification of nanostructured coatings with focus on size effect in nanometric scale. Size effect on electrochemical, mechanical and physical properties of nanocoatings are presented.

This book provides an up-to-date review of nanometer-scale magnetism and focuses on the investigation of the basic properties of magnetic nanostructures. It describes a wide range of physical aspects together with theoretical and experimental methods. A broad overview of the latest developments in this emerging and fascinating field of nanostructured materials is given with emphasis on the practical understanding and operation of submicron devices based on nanostructured magnetic materials.

This book deals with topics such as single molecular electronics and photonics, NICE devices, smart soft materials, interfacial dynamic technology, and fabrication and characterization technology.

I ?rst heard of k.p in a course on semiconductor physics taught by my thesis adviser William Paul at Harvard in the fall of 1956. He presented the k.p Hamiltonian as a semiempirical theoretical tool which had become rather useful for the interpre- tion of the cyclotron resonance experiments, as reported by Dresselhaus, Kip and Kittel. This perturbation technique had already been succinctly discussed by Sho- ley in a now almost forgotten 1950 Physical Review publication. In 1958 Harvey Brooks, who had returned to Harvard as Dean of the Division of Engineering and Applied Physics in which I was enrolled, gave a lecture on the capabilities of the k.p technique to predict and 't non-parabolicities of band extrema in semiconductors. He had just visited the General Electric Labs in Schenectady and had discussed with Evan Kane the latter's recent work on the non-parabolicity of band extrema in semiconductors, in particular InSb. I was very impressed by Dean Brooks's talk as an application of quantum mechanics to current real world problems. During my thesis work I had performed a number of optical measurements which were asking for theoretical interpretation, among them the dependence of effective masses of semiconductors on temperature and carrier concentration. Although my theoretical ability was rather limited, with the help of Paul and Brooks I was able to realize the capabilities of the k.p method for interpreting my data in a simple way."

This book provides an introduction to robot-based nanohandling. It presents work on the development of a versatile microrobot-based nanohandling robot station inside a scanning electron microscope (SEM). Those unfamiliar with the subject will find the text, which is complemented throughout by the extensive use of illustrations, clear and simple to understand. The author has published two books and numerous papers in the field, and holds more than 50 patents.

Tian Lu's dissertation describes major advances in ultrathin-layer chromatography (UTLC), liquid chromatography and surface-assisted laser desorption ionization (SALDI), and matrix-enhanced SALDI (ME-SALDI) mass spectrometry. Lu describes the fabrication of electrospun polyvinyl alcohol (PVA) UTLC plates using an in-situ crosslinking electrospinning technique. The author improved the efficiency of PVA plates greatly compared to the efficiency of silica HPTLC plates. Also highlighted in this thesis is an edge-plane based ordered-carbon surface that provides unique selectivity in liquid chromatography. Further developments include polar analytes, such as amino acids, nucleotides and nucleosides which can be well-retained and separated in the edge-plane ordered-carbon stationary phase. Also, the author studied and detected mass spectra of organic polymers as high as 900,000 Da, the highest molecular weight that has been studied by SALDI to date using the carbon nanofibrous substrate. This thesis has led to a number of publications in high-impact journals.

This book introduces the reader to drug delivery with specific emphasis on the use of nanoparticles. It covers properties, characterization, and preparation of different types of nanoparticles and discusses recent advances in their structural design and biomedical application, as well as the issues and challenges associated with their design and use. Some of the topics covered include the potential application of nanoparticles in biomedical fields, hazards associated with use of nanoparticles for drug delivery, size-dependent factors in drug delivery applications, different organic, inorganic and their hybrid systems used in drug delivery, etc. It also highlights use of nanoparticles in controlled and targeted drug delivery, and their application in stimuli-responsive, especially pH-responsive, drug release. Additionally, it also focuses on biomimetic nanoparticles, challenges faced in the designing of nanoparticles for drug delivery in cancer, viral and bacterial diseases. The contents of this volume will be useful to researchers and professionals working on advances in targeted drug delivery systems.

A dense sheet of electrons accelerated to close to the speed of light can act as a tuneable mirror that can generate bright bursts of laser-like radiation in the short wavelength range simply via the reflection of a counter-propagating laser pulse. This thesis investigates the generation of such a relativistic electron mirror structure in a series of experiments accompanied by computer simulations. It is shown that such relativistic mirror can indeed be created from the interaction of a high-intensity laser pulse with a nanometer-scale, ultrathin foil. The reported work gives a intriguing insight into the complex dynamics of high-intensity laser-nanofoil interactions and constitutes a major step towards the development of a relativistic mirror, which could potentially generate bright burst of X-rays on a micro-scale.

Most textbooks explain quantum mechanics as a story where each step follows naturally from the one preceding it. However, the development of quantum mechanics was exactly the opposite. It was a zigzag route, full of personal disputes where scientists were forced to abandon well-established classical concepts and to explore new and imaginative pathways. Some of the explored routes were successful in providing new mathematical formalisms capable of predicting experiments at the atomic scale. However, even such successful routes were painful enough, so that relevant scientists like Albert Einstein and Erwin Schroedinger decided not to support them. In this book, the authors demonstrate the huge practical utility of another of these routes in explaining quantum phenomena in many different research fields. Bohmian mechanics, the formulation of the quantum theory pioneered by Louis de Broglie and David Bohm, offers an alternative mathematical formulation of quantum phenomena in terms of quantum trajectories. Novel computational tools to explore physical scenarios that are currently computationally inaccessible, such as many-particle solutions of the Schroedinger equation, can be developed from it.

Nanomedicine is the field of science that deals with organic applications of medicine at the nano-scale level. It primarily addresses finding, anticipating, and treating sickness, as well as using nanotechnology to assist in controlling human frameworks at the cellular level. The nature of nanotechnology allows it to address numerous medical issues in humans. This book offers comprehensive information to better comprehend and apply multifunctional nanoparticles in nanomedicine, and thus open avenues in the field. Medicating at the nanolevel is an exceptional therapeutic avenue, as it avoids symptoms associated with conventional medicines. This book investigates recent insights into structuring novel drug delivery frameworks. It concentrates on the physical characteristics of drug delivery transporters, and the preliminary procedures involved in their use. The book offers in-depth detail that benefits academics and researchers alike, containing broad research from experts in the field, and serves as a guide for students and researchers in the field of nanomedicine, drug delivery, and nanotechnology.

Metal Oxide Nanoparticles in Organic Solvents discusses recent advances in the chemistry involved for the controlled synthesis and assembly of metal oxide nanoparticles, the characterizations required by such nanoobjects, and their size and shape depending properties.

In the last few years, a valuable alternative to the well-known aqueous sol-gel processes was developed in the form of nonaqueous solution routes. Metal Oxide Nanoparticles in Organic Solvents reviews and compares surfactant- and solvent-controlled routes, as well as providing an overview of techniques for the characterization of metal oxide nanoparticles, crystallization pathways, the physical properties of metal oxide nanoparticles, their applications in diverse fields of technology, and their assembly into larger nano- and mesostructures.

Researchers and postgraduates in the fields of nanomaterials and sol-gel chemistry will appreciate this book s informative approach to chemical formation mechanisms in relation to metal oxides.

This book traces the quest to use nanostructured media for novel and improved optoelectronic devices. Starting with the invention of the heterostructure laser, the progression via thin films to quasi zero-dimensional quantum dots has led to novel device concepts and tremendous improvements in device performance. Along the way sophisticated methods of material preparation and characterization have been developed. Novel physical phenomena have emerged and are now used in devices such as lasers and optical amplifiers. Leading experts - among them Nobel laureate Zhores Alferov - write here about the fundamental concepts behind nano-optoelectronics, the material basis, physical phenomena, device physics and systems.