This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

This issue of Neurosurgery Clinics will focus on subdural hematomas. Articles will include: Imaging of Subdural Hematomas; Chronic Subdural Natural History; Chronic Subdural Medical Management; Chronic Subdural Minimally Invasive Surgery; Chronic Subdural Craniotomy; Chronic Subdural ICU Management; and many more!

Most individuals with brain damage experience a curtailment or loss of lifestyle without rehabilitation. Improved methods and appropriately timed medical interventions now make it possible for more individuals to survive brain insults and to be assisted by rehabilitation neuropsychologists in achieving renewed commitment to life. Damage to the brain -- the organ of human emotions and cognition -- reduces psychological functioning and realistic adaptation, and the patient and his/her family are often encapsulated in the time prior to injury. To regain part or most of the lifestyle lost, an honest, dedicated, and realistic approach is required. Neuropsychological rehabilitation can provide tools for this task, provided that the most comprehensive, elaborate and knowledge-based methods are integrated in the training, and provided that knowledge from many disciplines and from community environments and family is encompassed.
In the present book knowledge representing the development of neuropsychological rehabilitation during the past five years is collected from a conference titled "Progress in Neuropsychological Rehabilitation." The chapters are written by professionals who were invited to share their experiences from different areas within the field because of their expertise with processes involved in neuropsychological rehabilitation. After a historical review, the chapters follow a visible sequence from biology to neuropsychology and neuropharmacology. Experts discuss the most advanced medical knowledge of the effect of injury on states of the organism. The second part of the book is dedicated to the outcome and the economics of rehabilitation as well as plans for the future. Finally, a panel discussion addresses the overall concept: Is rehabilitation worthwhile and ethical? The reactions -- influenced by the cross-cultural exchange of knowledge -- shed light on the essence and practice of today's neurorehabilitation.

The consequences of a brain injury can affect all aspects of our lives, including our personality. Brain injuries do not heal like other injuries and symptoms may appear right away or may not be present for days or weeks after the injury. This issue will include Past, Present, and Future of TBI research; Pathophysiology of TBI; Advances in brain imaging of TBI; and many more articles leading up to Degenerative Disease following Traumatic Brain Injury.

Intraoperative neurophysiological monitoring (IOM) has proven itself a versatile technique that reduces the risks of acquiring intraoperative neurological deficits, shortens operating time, and lowers the costs of medical care and rehabilitation. It can also reduce the risks of medical malpractice suits and serve as a research tool to better understand nervous system disorders and promote improved treatments. In Intraoperative Neurophysiological Monitoring, Second Edition, the premier authority on the subject, Aage R. Moller, has extensively expanded and rewritten his highly regarded first edition to create a comprehensive, up-to-date reference on IOM techniques and their anatomical and physiological basis. In addition, the author has added new material on the monitoring of the spinal motor system, sensory systems, peripheral nerves, and in skull base surgery. Writing as a pioneer and leader in the field, Dr. Moller provides practical information about how to perform electrophysiological recordings in the operating room, interpret the results, and present them to the surgeon. Included are descriptions of methods for guiding the surgeon in such operations as microvascular decompression and the implantation of electrodes for deep brain stimulation and auditory prostheses. Methods for mapping of the cerebral cortex, the brainstem, and the spinal cord are also described, as well as practical procedures for monitoring cranial motor nerves. Practical aspects of IOM including requirements of equipment, reducing electrical and magnetic interference, and how to work with other teams in the operating room are discussed in detail. Comprehensive and up-to-date, Intraoperative Neurophysiological Monitoring, Second Edition, is an authoritative survey of the theoretical and practical knowledge needed to reduce the risks that occur in surgical operations impacting the nervous system.

Advances: H. Duffau: Subpial dissection and subcortical mapping with vasculature and white matter pathways preservation in surgery for brain (low grade) gliomas. - F. Scholtes, G. Brook, D. Martin: Spinal cord injury and its treatment: current management and experimental perspectives. - M. Sindou, M. Messerer, J. Alvernia, G. Saint-Pierre: Percutaneous Biopsy through the Foramen Ovale for Parasellar lesions: Surgical anatomy, Method and Indications. - Technical Standards: C. Raftopoulos, F. Waterkeyn, E. Fomekong, T. Duprez: Percutaneous pedicle screw implantation with robotic intraoperative 2D/3D fluoroscopy for refractory low back pain. I. Zemmoura, S. Velut, P. Francois: The choroidal fissure: anatomy and surgical implications. I. Timofeev, T. Santarius, A.G. Kolias, P.J.A. Hutchinson: Decompressive craniectomy operative technique and perioperative care. - S Fauser, J Zentner: Management of complex cortical dysplasia in epilepsy

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Up to date and evidence-based answers to a wide range of spinal surgical questions that could be asked in the FRCS (Tr & Orth) Viva exam. Using a clear, case-based structure key points emphasise the core information that will improve the performance of every surgical in training. Sections cover all the key areas of Trauma, Degenerative spinal pathology, Spinal cord injury, Spinal deformity, Primary bone tumours, Metastatic disease, Paediatric spinal surgery, Basic sciences, and other topics. Suitable for use by trainees at all levels in orthopaedic surgery and neurosurgery, both in the UK and internationally, and those with an interest in spinal surgery.

Advice for the preparation and execution of clinical and viva components of the Neurosurgical Examinations Comprehensive relevant examination scenarios Key steps in performing the neurological examination Salient points of scientific examination topics

This issue provides a glimpse into how pain can be assessed and managed by several medical disciplines and approaches. It covers classical and conventional techniques as well as innovative techniques.

This issue of Neurosurgery Clinics of North America is devoted to "Minimally Invasive Spine Surgery"?and is edited by Zachary A. Smith, MD and Richard G. Fessler, MD, PhD. Articles in this issue include: Complications and complication avoidance of minimally invasive spine surgery; Radiation exposure risk and avoidance; Current techniques in the management of cervical myelopathy and radiculopathy; Thoracic disc/pathology management through minimally invasive routes; Transforaminal Lumbar Interbody fusion: Long term outcomes and complications; Computer-assisted navigation technique for minimally invasive transforaminal lumbar interbody fusion and lateral interbody fusion; Safety and the Anatomy of the retroperitoneal lateral corridor; Minimally invasive extracavitary transpedicular corpectomy for the management of spinal tumors; Minimally invasive anterolateral corpectomy for spinal tumors; Minimally invasive approaches for the management of intramedullary spinal tumors; Percutaneous fixation of thoracolumbar fractures; Advances and feasibility of advanced minimally invasive techniques in deformity correction; Direct lateral approach: Outcomes and Deformity Correction; and Evidence basis and outcomes.

- All of the contributors are renowned experts in the field, and many are pioneers of radiosurgery (such as L. Dade Lunsford, Douglas Kondziolka, Jason Sheehan, Jean Regis).

Here is the second, completely revised and updated edition of the successful practical guide to image-guided spine intervention. It contains revised text and images as well as new sections and chapters. The updated text thoroughly discusses both well-established and new interventions that are applied to the spine for the purpose of pain relief.

Distinguished medical researchers from around the world review novel neural reconstructive techniques that appear to be beneficial for Parkinson's disease and hold promise for treating Huntington's disease, pain, demyelinating diseases, and stroke. The contributors focus on those diseases for which clinical trials are either ongoing or likely to occur in the near future. Among the topics reviewed are results and rationale for some of the leading transplant programs for the treatment of Parkinson's disease, the use of PET scanning for patient evaluation, autopsy studies of transplant recipients, transplant immunology, fetal tissue transplantation for Huntington's disease, cellular transplantation for the treatment of pain and stroke, and transplantation of myelinating cells. A full discussion of the important ethical issues surrounding the use of fetal tissue for transplantation purposes is also included.

Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon's most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better." This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.

Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon's most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better." This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

This book presents a comprehensive interdisciplinary team approach to the rehabilitation of acquired brain injury (ABI) survivors. Medical and clinical specialists will receive a deeper understanding of not only each other's roles but of their complementary functions in this field. Many case examples are provided, illustrating a wide range of challenges and stages of recovery. This edition features 3 entirely new chapters and multiple updated chapters by new and returning authors. Featured in the coverage: The role of Robotics in acquired brain injury A comprehensive chapter on physical therapy in ABI Outstanding recoveries woven together by a video news producer who recovered from a meningioma State of the art updates on neurosurgery, neurology, physiatry, neuropsychiatry and neuro-optometry. Updated chapters on neuropsychology, speech-language and occupational therapies including new technology and approaches as well as evidence based practices Psychosocial challenges and treatment following ABI The importance of family as team members Post rehabilitation options and experiences Acquired Brain Injury: An Integrative Neuro-Rehabilitation Approach, 2nd edition provides clarity and context regarding the rehabilitation goals and processes for rehabilitation specialists, interdisciplinary students of neuro-rehabilitation as well as practicing clinicians interested in developing their knowledge in their field.

Guest Editors Rafael J. Tamargo and Judy Huang have focused on "Cranial Arteriovenous Malformations (AVMs) and Dural Arteriovenous Fistulas (DAVFs) in this issue of Neurosurgery Clinics of North America.? Articles in this issue include: ? Arteriovenous Malformations: Epidemiology and Clinical Presentation; Dural Arteriovenous Fistulas: Epidemiology and Clinical Presentation; Historical Perspective of Treatments of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Imaging of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Classification Schemes for Arteriovenous Malformations; Classification Schemes for Dural Arteriovenous Fistulas; Acute Management of Ruptured Arteriovenous Malformations and Dural Arteriovenous Fistulas; Selection of Treatment Modalities or Observation of Arteriovenous Malformations; Selection of Treatment Modalities or Observation of Dural Arteriovenous Malformations; Surgical Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Anesthesia Considerations and Intraoperative Monitoring During Surgery for Arteriovenous Malformations and Dural Arteriovenous Fistulas; Stereotactic Radiosurgery of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Endovascular Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Malformations; Occlusive Hyperemia Versus Normal Perfusion Pressure Breakthrough after Treatment of Cranial Arteriovenous Malformations; Vein of Galen Malformations: Epidemiology, Clinical Presentation, and Management; Carotid Cavernous Fistulas: Epidemiology, Clinical Presentation, and Management

Guest Edited by experts Paul Nyquist, Neeraj Naval, and Rafael Tamargo of Johns Hopkins, this issue covers a wide range of topics related to Aneurysmal Subarachnoid Hemorrhage, including epidemiology, surgical management, endovascular treatment, non-invasive imaging techniques, risk factors and medical management of vasospasm, cerebral salt wasting, outcomes and costs, medical complications, and more.

This book covers the entire spectrum of cerebellopontine angle lesions, from the most common to the rarest. All aspects are considered, including biological and radiological characteristics, neurological presentation, diagnosis, treatment options and follow-up care. The main focus, however, is on surgical management, which is presented in detail with the aid of numerous figures and images documenting technical particularities. Emphasis is placed on an individualized approach tailored to the particular tumor type and extension pattern. Both novice and experienced surgeons will find the book to be an invaluable source of information and guidance. It will enable neurosurgeons in the initial years of training to understand and become familiar with the main steps in surgical management while simultaneously providing their senior colleagues with details and technical tips that will help to improve treatment results.

For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy.? The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.

This book follows a context-based approach to management of early-onset scoliosis (EOS) in countries with limited resources in education, finance, and research. Due to the great variety in etiology, onset age, progression rate, and severity associated with EOS, it calls for a unique treatment plan. This book enumerates the optimal provision of surgical and non-surgical services, from education/training of local surgeons, to effective teamwork, to implementing an effective data collection system; helping the surgeon to gain a hands-on experience. It also illustrates the successful execution of deformity correction using real life experiences from countries in Asia, Africa, and Latin America. Key Features Discusses biomedical principles that will help to get universally standard implants that are credible and affordable for countries with limited resources. Specific surgical Guidelines and the ability to develop evidence-based practice for this service would be an interesting read for surgeons working in global organizations as well as to local surgeons. First book to focus on countries with limited resources for the management of early onset scoliosis.

This issue is the last of a two-part series dedicated to Neuroendovasular Management and Guest Edited by Robert Rosenwasser and Pascal Jabbour of Jefferson. Part two covers topics such as Neuroendovascular Management of Carotid Cavernous Fistulae, Endovascular Management of Intracranial Aneurysms, Neuroendovascular Management of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage, Neuroendovascular Management of Acute Ischemic Stroke, and many more.

Minimally invasive procedures are increasingly utilized and are replacing open surgery to reduce scarring and pain, enhance patient recovery, and minimize cost. Minimally Invasive Spine Surgery provides step-by-step guidance, expert instruction, and detailed illustration of current minimally invasive orthopedic spine procedures. With a variety of chapters covering critical developments in the field-including the utilization of biologic materials, image-guided surgery, and bone fusion-this guide delves into discussions of indications, methods for preoperative planning, complication avoidance strategies, and patient outcomes. Covering emerging technologies and biological advances that will result in smaller incisions, less trauma, and enhanced patient rehabilitation, this book: Helps surgeons identify key anatomical structures for minimally invasive access Considers preoperative planning, complications, and outcomes for all operative methods Updates surgeons on significant advances in bone graft substitutes for spine fusion Details decompression and mini-open surgical techniques-all intended to achieve less traumatic surgical treatments and improve patient outcomes Includes a section on needle-based procedures for chronic pain relief

Unique in the field, Intrinsic and Skull Base Tumors presents commonly encountered skull base and intrinsic neoplasm cases with side-by-side, case-by-case comparisons that clearly show how various experts would handle the same case. This inaugural volume in the Neurosurgery: Case Comparison Series offers multiple opinions from international experts in neurosurgery who provide various approaches and management styles for the same case. This format allows for quick and helpful comparisons of different ways to approach a lesion, advantages and disadvantages of each approach, and what each expert is looking for in how they would manage a particular case. Offers 3 to 4 expert opinions on each case in a templated format designed to help you quickly make side-by-side comparisons-an ideal learning tool for both trainees and practicing neurosurgeons for board review and case preparation. Helps you easily grasp different approaches to brain tumor management with different expert approaches to the same case and summaries from the editors on the advantages and disadvantages to each approach. Features a wide variety of management decisions, from preoperative studies to surgical approach, surgical adjuncts, and postoperative care, from experts in the field who specialize in different aspects of neurosurgery. Covers low and high grade gliomas, metastatic brain cancers, meningiomas, sellar and parasellar lesions, skull base lesions, and other brain lesions such as colloid cyst, cavernoma, hemangioblastoma, brain abscess, and more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.