This volume provides a full explanation and technical details to perform surgical techniques properly on small and large animal models. The first six chapters of Experimental Neurosurgery in Animal Models focus primarily on the brain, while the next six chapters concern the spinal cord in rodents. The last four chapters provide a description of operative procedures in large animals. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory. Authoritative and practical, Experimental Neurosurgery in Animal Models aims to ensure successful results in the further study of this vital field.

Intraoperative neurophysiological monitoring (IOM) has proven itself a versatile technique that reduces the risks of acquiring intraoperative neurological deficits, shortens operating time, and lowers the costs of medical care and rehabilitation. It can also reduce the risks of medical malpractice suits and serve as a research tool to better understand nervous system disorders and promote improved treatments. In Intraoperative Neurophysiological Monitoring, Second Edition, the premier authority on the subject, Aage R. Moller, has extensively expanded and rewritten his highly regarded first edition to create a comprehensive, up-to-date reference on IOM techniques and their anatomical and physiological basis. In addition, the author has added new material on the monitoring of the spinal motor system, sensory systems, peripheral nerves, and in skull base surgery. Writing as a pioneer and leader in the field, Dr. Moller provides practical information about how to perform electrophysiological recordings in the operating room, interpret the results, and present them to the surgeon. Included are descriptions of methods for guiding the surgeon in such operations as microvascular decompression and the implantation of electrodes for deep brain stimulation and auditory prostheses. Methods for mapping of the cerebral cortex, the brainstem, and the spinal cord are also described, as well as practical procedures for monitoring cranial motor nerves. Practical aspects of IOM including requirements of equipment, reducing electrical and magnetic interference, and how to work with other teams in the operating room are discussed in detail. Comprehensive and up-to-date, Intraoperative Neurophysiological Monitoring, Second Edition, is an authoritative survey of the theoretical and practical knowledge needed to reduce the risks that occur in surgical operations impacting the nervous system.

Advances: H. Duffau: Subpial dissection and subcortical mapping with vasculature and white matter pathways preservation in surgery for brain (low grade) gliomas. - F. Scholtes, G. Brook, D. Martin: Spinal cord injury and its treatment: current management and experimental perspectives. - M. Sindou, M. Messerer, J. Alvernia, G. Saint-Pierre: Percutaneous Biopsy through the Foramen Ovale for Parasellar lesions: Surgical anatomy, Method and Indications. - Technical Standards: C. Raftopoulos, F. Waterkeyn, E. Fomekong, T. Duprez: Percutaneous pedicle screw implantation with robotic intraoperative 2D/3D fluoroscopy for refractory low back pain. I. Zemmoura, S. Velut, P. Francois: The choroidal fissure: anatomy and surgical implications. I. Timofeev, T. Santarius, A.G. Kolias, P.J.A. Hutchinson: Decompressive craniectomy operative technique and perioperative care. - S Fauser, J Zentner: Management of complex cortical dysplasia in epilepsy

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This issue provides a glimpse into how pain can be assessed and managed by several medical disciplines and approaches. It covers classical and conventional techniques as well as innovative techniques.

This issue of Neurosurgery Clinics of North America is devoted to "Minimally Invasive Spine Surgery"?and is edited by Zachary A. Smith, MD and Richard G. Fessler, MD, PhD. Articles in this issue include: Complications and complication avoidance of minimally invasive spine surgery; Radiation exposure risk and avoidance; Current techniques in the management of cervical myelopathy and radiculopathy; Thoracic disc/pathology management through minimally invasive routes; Transforaminal Lumbar Interbody fusion: Long term outcomes and complications; Computer-assisted navigation technique for minimally invasive transforaminal lumbar interbody fusion and lateral interbody fusion; Safety and the Anatomy of the retroperitoneal lateral corridor; Minimally invasive extracavitary transpedicular corpectomy for the management of spinal tumors; Minimally invasive anterolateral corpectomy for spinal tumors; Minimally invasive approaches for the management of intramedullary spinal tumors; Percutaneous fixation of thoracolumbar fractures; Advances and feasibility of advanced minimally invasive techniques in deformity correction; Direct lateral approach: Outcomes and Deformity Correction; and Evidence basis and outcomes.

Integrates basic research and practical clinical information on the neuropsychology of epilepsy under one cover. Provides inside knowledge on how neuropsychological assessments are performed and evaluated. A comprehensive reference that will serve as a clinical resource for working with epilepsy patients. Epilepsy is a prevalent condition affecting approximately 1% of the general population. Its behavioral effects on cognition and memory can be as debilitating as the physical aspects caused by ongoing seizures. This book is intended primarily for clinical neuropsychologists who encounter patients with epilepsy, either through employment in academic medical centers or in general practice. The book is of particular value to those working in a comprehensive epilepsy center, as the volume provides extensive coverage of the many clinical procedures performed in that setting. Procedures reviewed in this volume include neuropsychological testing, the Wada procedures, and brain mapping. Chapters include descriptions of the purpose of these procedures, reviews of the recent literature, clinical vignettes, in addition to concrete recommendations on how to actually conduct the procedures. Many chapters provide examples of test forms and stimuli useful for conducting some of the procedures reviewed in this book. Neurologists and pediatricians will also find this book to be helpful, as many medical practitioners consider the activities of clinical neuropsychologists working in their settings to be somewhat mysterious. This book makes the details of neuropsychological practice in an epilepsy setting more accessible than what has been present in prior literature. Content Level Research Keywords Brain mapping - Children with epilepsy - Cognitive remediation - Epilepsy - Epilepsy in children - FMRI - MEG - Movement disorder - Neuropsychological testing - Refractory seizure - Seizure - Seizure disorder - Wada test Related subjects Neurology - Ne

Integrated Neuroscience argues that in order to make an intelligent diagnosis and provide a rational treatment nervous system disorders, it is necessary to answer the basic questions of clinical neurology. Where is the disease process located, and what is the nature of the disease process? For students to answer these questions, the authors first review the makeup of the cells within the central nervous system and the development of the regions within the central nervous system. A detailed anatomical overview of the nervous system, starting at the spinal cord, proceeding to the brain stem, diencephalon and cerebrum follows. This textbook focuses not only on localized diseases caused by infectious diseases, trauma, tumors, and vascular lesions within the central nervous system, but also these diseases within the systems of the brain and spinal cord. Over 250 real cases with associated MRI or CTs and any pathological findings from these patients illustrate numerous disorders and fully explain the nature of the pathology. The authors have also included six problem solving sessions in which the student must identify the ongoing disease process, what caused it, and how best to treat it. Throughout the discussion in this text the authors also correlate the neurological findings to the underlying anatomy of the region.

Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon's most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better." This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.

Distinguished medical researchers from around the world review novel neural reconstructive techniques that appear to be beneficial for Parkinson's disease and hold promise for treating Huntington's disease, pain, demyelinating diseases, and stroke. The contributors focus on those diseases for which clinical trials are either ongoing or likely to occur in the near future. Among the topics reviewed are results and rationale for some of the leading transplant programs for the treatment of Parkinson's disease, the use of PET scanning for patient evaluation, autopsy studies of transplant recipients, transplant immunology, fetal tissue transplantation for Huntington's disease, cellular transplantation for the treatment of pain and stroke, and transplantation of myelinating cells. A full discussion of the important ethical issues surrounding the use of fetal tissue for transplantation purposes is also included.

Here is the second, completely revised and updated edition of the successful practical guide to image-guided spine intervention. It contains revised text and images as well as new sections and chapters. The updated text thoroughly discusses both well-established and new interventions that are applied to the spine for the purpose of pain relief.

Up to date and evidence-based answers to a wide range of spinal surgical questions that could be asked in the FRCS (Tr & Orth) Viva exam. Using a clear, case-based structure key points emphasise the core information that will improve the performance of every surgical in training. Sections cover all the key areas of Trauma, Degenerative spinal pathology, Spinal cord injury, Spinal deformity, Primary bone tumours, Metastatic disease, Paediatric spinal surgery, Basic sciences, and other topics. Suitable for use by trainees at all levels in orthopaedic surgery and neurosurgery, both in the UK and internationally, and those with an interest in spinal surgery.

This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.
Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research
Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered
All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

Guest Editors Rafael J. Tamargo and Judy Huang have focused on "Cranial Arteriovenous Malformations (AVMs) and Dural Arteriovenous Fistulas (DAVFs) in this issue of Neurosurgery Clinics of North America.? Articles in this issue include: ? Arteriovenous Malformations: Epidemiology and Clinical Presentation; Dural Arteriovenous Fistulas: Epidemiology and Clinical Presentation; Historical Perspective of Treatments of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Imaging of Arteriovenous Malformations and Dural Arteriovenous Fistulas; Classification Schemes for Arteriovenous Malformations; Classification Schemes for Dural Arteriovenous Fistulas; Acute Management of Ruptured Arteriovenous Malformations and Dural Arteriovenous Fistulas; Selection of Treatment Modalities or Observation of Arteriovenous Malformations; Selection of Treatment Modalities or Observation of Dural Arteriovenous Malformations; Surgical Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Anesthesia Considerations and Intraoperative Monitoring During Surgery for Arteriovenous Malformations and Dural Arteriovenous Fistulas; Stereotactic Radiosurgery of Cranial Arteriovenous Malformations and Dural Arteriovenous Fistulas; Endovascular Treatment of Cranial Arteriovenous Malformations and Dural Arteriovenous Malformations; Occlusive Hyperemia Versus Normal Perfusion Pressure Breakthrough after Treatment of Cranial Arteriovenous Malformations; Vein of Galen Malformations: Epidemiology, Clinical Presentation, and Management; Carotid Cavernous Fistulas: Epidemiology, Clinical Presentation, and Management

- All of the contributors are renowned experts in the field, and many are pioneers of radiosurgery (such as L. Dade Lunsford, Douglas Kondziolka, Jason Sheehan, Jean Regis).

Advice for the preparation and execution of clinical and viva components of the Neurosurgical Examinations Comprehensive relevant examination scenarios Key steps in performing the neurological examination Salient points of scientific examination topics

This book presents a comprehensive interdisciplinary team approach to the rehabilitation of acquired brain injury (ABI) survivors. Medical and clinical specialists will receive a deeper understanding of not only each other's roles but of their complementary functions in this field. Many case examples are provided, illustrating a wide range of challenges and stages of recovery. This edition features 3 entirely new chapters and multiple updated chapters by new and returning authors. Featured in the coverage: The role of Robotics in acquired brain injury A comprehensive chapter on physical therapy in ABI Outstanding recoveries woven together by a video news producer who recovered from a meningioma State of the art updates on neurosurgery, neurology, physiatry, neuropsychiatry and neuro-optometry. Updated chapters on neuropsychology, speech-language and occupational therapies including new technology and approaches as well as evidence based practices Psychosocial challenges and treatment following ABI The importance of family as team members Post rehabilitation options and experiences Acquired Brain Injury: An Integrative Neuro-Rehabilitation Approach, 2nd edition provides clarity and context regarding the rehabilitation goals and processes for rehabilitation specialists, interdisciplinary students of neuro-rehabilitation as well as practicing clinicians interested in developing their knowledge in their field.

Robotic spine surgery is one of the fastest growing segments of the spine surgery market. Surgeons specialising in spine surgery are highly motivated to learn and improve their understanding of the indications,application,and future clinical scope of using new technological platforms. Spinal surgeons face time pressures but are hungry for new ways to effectively treat patients. This book presents information in the case study format. By using examples of surgical cases of an advanced nature (e.g. spinal deformity, minimally invasive surgery, combinatorial technology using the robot) this will differ from other texts. Each case study is written by a well-respected expert in the field and represents that surgeon's most monumental case. Each case contains a concise patient history with indications, contraindications and insights to help the reader assimilate expert knowledge. The case studies examine both the unique and technical aspects of robotic planning and surgical execution, and include seminal bullet point sections: Key take away points; Tips and pearls to avoid pitfalls; and "how I could have done this better." This new text provides valuable and practical knowledge for spine surgeons and others involved in robotic surgery.

'Sensational' SUNDAY TIMES NO. BESTSELLER 'Extraordinary...both exhilarating and alarming...fascinating' DAILY MAIL 'Wonderful...a testament to the tenacity of the human spirit' FINANCIAL TIMES Henry Marsh has spent four decades operating on the human brain. In this searing and provocative memoir following his retirement from the NHS, he reflects on the experiences that have shaped his career and life, gaining a deeper understanding of what matters to us all in the end.

Perfect for anyone considering or training in this challenging specialty, Principles of Neurological Surgery, 4th Edition, by Drs. Richard G. Ellenbogen, Laligam N. Sekhar, and Neil Kitchen, provides a clear, superbly illustrated introduction to all aspects of neurosurgery-from general principles to specific techniques. Thorough updates from leading authors ensure that you'll stay abreast of the latest advances in every area of neurosurgery, including pre- and post-operative patient care, neuroradiology, pediatric neurosurgery, neurovascular surgery, trauma surgery, spine surgery, oncology, pituitary adenomas, cranial base neurosurgery, image-guided neurosurgery, treatment of pain, epilepsy surgery, and much more. Offers comprehensive coverage without being encyclopedic - just the right amount of information for those in training or who need an introduction to the field. Provides a strong visual understanding of the essentials of neurosurgery with abundant high-quality illustrations, including imaging, pathology, clinical and operative photographs, surgical line drawings, diagrams, tables, and figures. Presents information in an easy-to-understand, well-written manner, helping you quickly grasp the principles and problems of today's neurosurgery. Features new and improved videos, more emphasis on anatomy and radiology, and new evidence and techniques, keeping you up to date with the latest advances in the field. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Problem Based Neurosurgery is a remarkable fusion of recent advances in neuro-imaging and neurosurgery with modern teaching of integrated system based curricula. It approaches each problem systematically from history, and physical examination to differential diagnosis, investigations and management options. The book captures four decades of advances and experiences in diagnosis and management of patients. The problems upon which the book is based are real patients and cover all aspects of neurosurgical practice with up to date modern images. The blend of new scientific discoveries, modern imaging and the art of smart history and physical examinations underpins the book to improve diagnosis, investigation and the care of neurosurgical patients.The main thrust of this book is that it is based on clinical problems faced by fellows, residents and students, rather than traditional topic based. Problem based learning and management is the modern method of teaching in the new curriculum of teaching neurosurgery. It is a practical handbook that will help students, residents and community doctors alike. There is no similar book on the market that fulfills the objectives of this handbook.

Guest Edited by experts Paul Nyquist, Neeraj Naval, and Rafael Tamargo of Johns Hopkins, this issue covers a wide range of topics related to Aneurysmal Subarachnoid Hemorrhage, including epidemiology, surgical management, endovascular treatment, non-invasive imaging techniques, risk factors and medical management of vasospasm, cerebral salt wasting, outcomes and costs, medical complications, and more.

This book covers the entire spectrum of cerebellopontine angle lesions, from the most common to the rarest. All aspects are considered, including biological and radiological characteristics, neurological presentation, diagnosis, treatment options and follow-up care. The main focus, however, is on surgical management, which is presented in detail with the aid of numerous figures and images documenting technical particularities. Emphasis is placed on an individualized approach tailored to the particular tumor type and extension pattern. Both novice and experienced surgeons will find the book to be an invaluable source of information and guidance. It will enable neurosurgeons in the initial years of training to understand and become familiar with the main steps in surgical management while simultaneously providing their senior colleagues with details and technical tips that will help to improve treatment results.

For this issue, Dr. Michael Lim of Johns Hopkins and Dr. Isaac Yang of UCSF team up to deliver a packed issue on the latest developments in Immunotherapy.? The issue covers hot topics such as immunostimulants, Passive Antibody Mediated Immunotherapy, Clinical Applications of A Peptide Based Vaccine, Challenges for Clinical Design of Immunotherapy Trials, The EGFRv3 Peptide Vaccine, Stem Cell Therapy and Dendritic Cell Vaccines, Dendritic Glioma Fusion Vaccine, Adoptive Cellular Immunotherapy, Virus Mediated Immunotherapy, and so much more.

Unique in the field, Intrinsic and Skull Base Tumors presents commonly encountered skull base and intrinsic neoplasm cases with side-by-side, case-by-case comparisons that clearly show how various experts would handle the same case. This inaugural volume in the Neurosurgery: Case Comparison Series offers multiple opinions from international experts in neurosurgery who provide various approaches and management styles for the same case. This format allows for quick and helpful comparisons of different ways to approach a lesion, advantages and disadvantages of each approach, and what each expert is looking for in how they would manage a particular case. Offers 3 to 4 expert opinions on each case in a templated format designed to help you quickly make side-by-side comparisons-an ideal learning tool for both trainees and practicing neurosurgeons for board review and case preparation. Helps you easily grasp different approaches to brain tumor management with different expert approaches to the same case and summaries from the editors on the advantages and disadvantages to each approach. Features a wide variety of management decisions, from preoperative studies to surgical approach, surgical adjuncts, and postoperative care, from experts in the field who specialize in different aspects of neurosurgery. Covers low and high grade gliomas, metastatic brain cancers, meningiomas, sellar and parasellar lesions, skull base lesions, and other brain lesions such as colloid cyst, cavernoma, hemangioblastoma, brain abscess, and more. Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.